메뉴 건너뛰기




Volumn 7, Issue 5, 2012, Pages

The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ; CHROMOGRANIN A; GASTRIC INHIBITORY POLYPEPTIDE; GASTRIN; GHRELIN; GLUCAGON LIKE PEPTIDE 1; HOMEODOMAIN PROTEIN; NEUROGENIN 3; PROTEIN ARX; SECRETIN; SEROTONIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PAX4; UNCLASSIFIED DRUG;

EID: 84860536527     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036449     Document Type: Article
Times cited : (76)

References (34)
  • 1
    • 0033679897 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
    • Date Y, Kojima M, Hosoda H, Sawaguchi A, Mondal MS, et al. (2000) Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 141: 4255-4261.
    • (2000) Endocrinology , vol.141 , pp. 4255-4261
    • Date, Y.1    Kojima, M.2    Hosoda, H.3    Sawaguchi, A.4    Mondal, M.S.5
  • 2
    • 0036171253 scopus 로고    scopus 로고
    • Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract
    • Sakata I, Nakamura K, Yamazaki M, Matsubara M, Hayashi Y, et al. (2002) Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract. Peptides 23: 531-536.
    • (2002) Peptides , vol.23 , pp. 531-536
    • Sakata, I.1    Nakamura, K.2    Yamazaki, M.3    Matsubara, M.4    Hayashi, Y.5
  • 3
    • 33845998516 scopus 로고    scopus 로고
    • The role of gut hormones in glucose homeostasis
    • Drucker DJ, (2007) The role of gut hormones in glucose homeostasis. JClinInvest 117: 24-32.
    • (2007) JClinInvest , vol.117 , pp. 24-32
    • Drucker, D.J.1
  • 4
    • 33845875966 scopus 로고    scopus 로고
    • Gut hormones and the regulation of energy homeostasis
    • Murphy KG, Bloom SR, (2006) Gut hormones and the regulation of energy homeostasis. Nature 444: 854-859.
    • (2006) Nature , vol.444 , pp. 854-859
    • Murphy, K.G.1    Bloom, S.R.2
  • 5
    • 77951849336 scopus 로고    scopus 로고
    • Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival
    • Mellitzer G, Beucher A, Lobstein V, Michel P, Robine S, et al. (2010) Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival. J Clin Invest 120: 1708-1721.
    • (2010) J Clin Invest , vol.120 , pp. 1708-1721
    • Mellitzer, G.1    Beucher, A.2    Lobstein, V.3    Michel, P.4    Robine, S.5
  • 6
    • 34249987090 scopus 로고    scopus 로고
    • Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis
    • Shroyer NF, Helmrath MA, Wang VY, Antalffy B, Henning SJ, et al. (2007) Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis. Gastroenterology 132: 2478-2488.
    • (2007) Gastroenterology , vol.132 , pp. 2478-2488
    • Shroyer, N.F.1    Helmrath, M.A.2    Wang, V.Y.3    Antalffy, B.4    Henning, S.J.5
  • 7
    • 0035824487 scopus 로고    scopus 로고
    • Requirement of Math1 for secretory cell lineage commitment in the mouse intestine
    • Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY, (2001) Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294: 2155-2158.
    • (2001) Science , vol.294 , pp. 2155-2158
    • Yang, Q.1    Bermingham, N.A.2    Finegold, M.J.3    Zoghbi, H.Y.4
  • 8
    • 0037011171 scopus 로고    scopus 로고
    • Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium
    • Jenny M, Uhl C, Roche C, Duluc I, Guillermin V, et al. (2002) Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J 21: 6338-6347.
    • (2002) EMBO J , vol.21 , pp. 6338-6347
    • Jenny, M.1    Uhl, C.2    Roche, C.3    Duluc, I.4    Guillermin, V.5
  • 9
    • 0037097981 scopus 로고    scopus 로고
    • Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity
    • Lee CS, Perreault N, Brestelli JE, Kaestner KH, (2002) Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Genes and Development 16: 1488-1497.
    • (2002) Genes and Development , vol.16 , pp. 1488-1497
    • Lee, C.S.1    Perreault, N.2    Brestelli, J.E.3    Kaestner, K.H.4
  • 10
    • 0034652287 scopus 로고    scopus 로고
    • neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
    • Gradwohl G, Dierich A, LeMeur M, Guillemot F, (2000) neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 97: 1607-1611.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1607-1611
    • Gradwohl, G.1    Dierich, A.2    LeMeur, M.3    Guillemot, F.4
  • 11
    • 33748251457 scopus 로고    scopus 로고
    • The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells
    • Gierl MS, Karoulias N, Wende H, Strehle M, Birchmeier C, (2006) The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells. Genes and Development 20: 2465-2478.
    • (2006) Genes and Development , vol.20 , pp. 2465-2478
    • Gierl, M.S.1    Karoulias, N.2    Wende, H.3    Strehle, M.4    Birchmeier, C.5
  • 12
    • 0030886674 scopus 로고    scopus 로고
    • Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice
    • Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo FJ, et al. (1997) Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev 11: 2323-2334.
    • (1997) Genes Dev , vol.11 , pp. 2323-2334
    • Naya, F.J.1    Huang, H.P.2    Qiu, Y.3    Mutoh, H.4    DeMayo, F.J.5
  • 13
    • 70949092295 scopus 로고    scopus 로고
    • Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice
    • Ye DZ, Kaestner KH, (2009) Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice. Gastroenterology 137: 2052-2062.
    • (2009) Gastroenterology , vol.137 , pp. 2052-2062
    • Ye, D.Z.1    Kaestner, K.H.2
  • 14
    • 37349015334 scopus 로고    scopus 로고
    • Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine
    • Desai S, Loomis Z, Pugh-Bernard A, Schrunk J, Doyle MJ, et al. (2008) Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine. Dev Biol 313: 58-66.
    • (2008) Dev Biol , vol.313 , pp. 58-66
    • Desai, S.1    Loomis, Z.2    Pugh-Bernard, A.3    Schrunk, J.4    Doyle, M.J.5
  • 16
    • 0030897629 scopus 로고    scopus 로고
    • The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas
    • Sosa-Pineda B, Chowdhury K, Torres M, Oliver G, Gruss P, (1997) The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature 386: 399-402.
    • (1997) Nature , vol.386 , pp. 399-402
    • Sosa-Pineda, B.1    Chowdhury, K.2    Torres, M.3    Oliver, G.4    Gruss, P.5
  • 18
    • 34147092649 scopus 로고    scopus 로고
    • Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression
    • Collombat P, Hecksher-Sorensen J, Krull J, Berger J, Riedel D, et al. (2007) Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression. JClinInvest 117: 961-970.
    • (2007) JClinInvest , vol.117 , pp. 961-970
    • Collombat, P.1    Hecksher-Sorensen, J.2    Krull, J.3    Berger, J.4    Riedel, D.5
  • 19
    • 68149162957 scopus 로고    scopus 로고
    • The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells
    • Collombat P, Xu X, Ravassard P, Sosa-Pineda B, Dussaud S, et al. (2009) The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells. Cell 138: 449-462.
    • (2009) Cell , vol.138 , pp. 449-462
    • Collombat, P.1    Xu, X.2    Ravassard, P.3    Sosa-Pineda, B.4    Dussaud, S.5
  • 20
    • 23144432613 scopus 로고    scopus 로고
    • The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas
    • Collombat P, Hecksher-Sorensen J, Broccoli V, Krull J, Ponte I, et al. (2005) The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas. Development 132: 2969-2980.
    • (2005) Development , vol.132 , pp. 2969-2980
    • Collombat, P.1    Hecksher-Sorensen, J.2    Broccoli, V.3    Krull, J.4    Ponte, I.5
  • 21
    • 38149057252 scopus 로고    scopus 로고
    • Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum
    • Wang Q, Elghazi L, Martin S, Martins I, Srinivasan RS, et al. (2008) Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum. Dev Dyn 237: 51-61.
    • (2008) Dev Dyn , vol.237 , pp. 51-61
    • Wang, Q.1    Elghazi, L.2    Martin, S.3    Martins, I.4    Srinivasan, R.S.5
  • 22
    • 72749102467 scopus 로고    scopus 로고
    • Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells
    • Chen C, Fang R, Davis C, Maravelias C, Sibley E, (2009) Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells. Am J Physiol Gastrointest Liver Physiol 297: G1126-1137.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.297
    • Chen, C.1    Fang, R.2    Davis, C.3    Maravelias, C.4    Sibley, E.5
  • 23
    • 0025296197 scopus 로고
    • Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression
    • Rindi G, Grant SG, Yiangou Y, Ghatei MA, Bloom SR, et al. (1990) Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression. Am J Pathol 136: 1349-1363.
    • (1990) Am J Pathol , vol.136 , pp. 1349-1363
    • Rindi, G.1    Grant, S.G.2    Yiangou, Y.3    Ghatei, M.A.4    Bloom, S.R.5
  • 24
    • 0036844387 scopus 로고    scopus 로고
    • Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans
    • Kitamura K, Yanazawa M, Sugiyama N, Miura H, Iizuka-Kogo A, et al. (2002) Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans. Nat Genet 32: 359-369.
    • (2002) Nat Genet , vol.32 , pp. 359-369
    • Kitamura, K.1    Yanazawa, M.2    Sugiyama, N.3    Miura, H.4    Iizuka-Kogo, A.5
  • 26
  • 27
    • 0036139165 scopus 로고    scopus 로고
    • Hepatic nuclear factor-3 (HNF-3 or Foxa2) regulates glucagon gene transcription by binding to the G1 and G2 promoter elements
    • Gauthier BR, Schwitzgebel VM, Zaiko M, Mamin A, Ritz-Laser B, et al. (2002) Hepatic nuclear factor-3 (HNF-3 or Foxa2) regulates glucagon gene transcription by binding to the G1 and G2 promoter elements. Mol Endocrinol 16: 170-183.
    • (2002) Mol Endocrinol , vol.16 , pp. 170-183
    • Gauthier, B.R.1    Schwitzgebel, V.M.2    Zaiko, M.3    Mamin, A.4    Ritz-Laser, B.5
  • 28
    • 0033557490 scopus 로고    scopus 로고
    • Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo
    • Kaestner KH, Katz J, Liu Y, Drucker DJ, Schutz G, (1999) Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo. Genes Dev 13: 495-504.
    • (1999) Genes Dev , vol.13 , pp. 495-504
    • Kaestner, K.H.1    Katz, J.2    Liu, Y.3    Drucker, D.J.4    Schutz, G.5
  • 29
    • 0026628841 scopus 로고
    • The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells
    • Leonard J, Serup P, Gonzalez G, Edlund T, Montminy M, (1992) The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells. Proc Natl Acad Sci U S A 89: 6247-6251.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 6247-6251
    • Leonard, J.1    Serup, P.2    Gonzalez, G.3    Edlund, T.4    Montminy, M.5
  • 30
    • 10744222257 scopus 로고    scopus 로고
    • Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation
    • Kato M, Das S, Petras K, Kitamura K, Morohashi K, et al. (2004) Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation. Hum Mutat 23: 147-159.
    • (2004) Hum Mutat , vol.23 , pp. 147-159
    • Kato, M.1    Das, S.2    Petras, K.3    Kitamura, K.4    Morohashi, K.5
  • 31
    • 34548859235 scopus 로고    scopus 로고
    • [Severe diarrhea associated with X-linked lissencephaly with absent corpus callosum and abnormal genitalia: a case report of successful treatment with the somatostatin analogue octreotide]
    • Nanba Y, Oka A, Ohno K, (2007) [Severe diarrhea associated with X-linked lissencephaly with absent corpus callosum and abnormal genitalia: a case report of successful treatment with the somatostatin analogue octreotide]. No To Hattatsu 39: 379-382.
    • (2007) No To Hattatsu , vol.39 , pp. 379-382
    • Nanba, Y.1    Oka, A.2    Ohno, K.3
  • 32
    • 77957320355 scopus 로고    scopus 로고
    • Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: consideration of pancreas differentiation
    • Itoh M, Takizawa Y, Hanai S, Okazaki S, Miyata R, et al. (2010) Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: consideration of pancreas differentiation. Differentiation 80: 118-122.
    • (2010) Differentiation , vol.80 , pp. 118-122
    • Itoh, M.1    Takizawa, Y.2    Hanai, S.3    Okazaki, S.4    Miyata, R.5
  • 33
    • 33746093870 scopus 로고    scopus 로고
    • Mutant neurogenin-3 in congenital malabsorptive diarrhea
    • Wang J, Cortina G, Wu SV, Tran R, Cho JH, et al. (2006) Mutant neurogenin-3 in congenital malabsorptive diarrhea. NEnglJMed 355: 270-280.
    • (2006) NEnglJMed , vol.355 , pp. 270-280
    • Wang, J.1    Cortina, G.2    Wu, S.V.3    Tran, R.4    Cho, J.H.5
  • 34
    • 0030601949 scopus 로고    scopus 로고
    • Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors
    • Gradwohl G, Fode C, Guillemot F, (1996) Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors. Dev Biol 180: 227-241.
    • (1996) Dev Biol , vol.180 , pp. 227-241
    • Gradwohl, G.1    Fode, C.2    Guillemot, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.