Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet

Journal of Biological Chemistry

Volumn 283, Issue 26, 2008, Pages 18365-18376

  Althage, Matthew C ^a   Ford, Eric L ^a   Wang, Songyan ^a   Tso, Patrick ^b   Polonsky, Kenneth S ^a   Wice, Burton M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; ANIMALS; ANTHROPOMETRY; CELLS; ENDOCRINOLOGY; GLUCOSE; HORMONES; INSULIN; LAWS AND LEGISLATION; NUTRITION; PLANTS (BOTANY); PLASMAS;

BLOOD GLUCOSE LEVELS; BODY WEIGHTS; CELL NUMBERS; CELL TYPES; DIPHTHERIA TOXINS; ENERGY EXPENDITURES; FOOD INTAKES; GLUCOSE HOMEOSTASISES; IN CONTROLS; INSULIN RESISTANCES; INSULIN SENSITIVITIES; INSULINOTROPIC POLYPEPTIDES; INTRAPERITONEAL; KNOCK OUTS; LONG TERMS; REGULATORY ELEMENTS; SMALL INTESTINES; TRANSGENIC; TRANSGENIC ANIMALS; TRANSGENIC MOUSE; WEIGHT GAINS; WEIGHT LOSSES; WILD TYPES;

CYTOLOGY;

DIPHTHERIA TOXIN; GASTRIC INHIBITORY POLYPEPTIDE; GENE THERAPY AGENT; GLUCOSE; INCRETIN; INSULIN; LEPTIN; UNCLASSIFIED DRUG; XENIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENERGY EXPENDITURE; FOOD INTAKE; GENE; GENE THERAPY; GIP DP GENE; GLUCOSE HOMEOSTASIS; HORMONE RELEASE; INSULIN LIKE ACTIVITY; INSULIN RESISTANCE; KILLER CELL; LIPID DIET; MOUSE; NEUROSECRETORY CELL; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC MOUSE; WEIGHT GAIN; ANIMAL; ANIMAL FOOD; BIOLOGICAL MODEL; FAT INTAKE; GENETICS; GLUCOSE TOLERANCE TEST; METABOLISM; RAT; TIME; TRANSGENE;

ANIMALIA; MUS; MUS MUSCULUS; RATTUS;

ANIMAL FEED; ANIMALS; DIETARY FATS; GASTRIC INHIBITORY POLYPEPTIDE; GLUCOSE TOLERANCE TEST; INCRETINS; INSULIN RESISTANCE; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; OBESITY; PROMOTER REGIONS (GENETICS); RATS; TIME FACTORS; TRANSGENES;

EID: 49649125933     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M710466200     Document Type: Article

References (72)

1. Aiken, K. D., Kisslinger, J. A., and Roth, K. A. (1994) Dev. Dyn. 201, 636-670
2. Roth, K. A., and Gordon, J. I. (1990) Proc. Natl. Acad. Sci. 87, 6408-6412
3. Sjolund, K., Sanden, G., Hakanson, R., and Sundler, F. (1983) Gastroenterology 85, 1120-1130
4. Brand, S. J., and Schmidt, W. E. (1995) in Textbook of Gastroenterology (Yamada, T., ed) pp. 25-741, JB Lippincott Company, Philadelphia
5. Walsh, J. H. (1994) in Physiology of the Gastrointestinal Tract (Johnson, L. R., ed) pp. 1-128, Raven Press, New York
6. Miller, L. J. (1999) in Textbook of Gastroenterology (Yamada, T., Alpers, D. H., Laine, L., Owyang, C., and Powell, D. W., eds) pp. 35-66, Lippincott Williams & Wilkens, Philadelphia
7. Nakazato, M., Murakami, N., Date, Y., Kojima, M., Matsuo, H., Kangawa, K., and Matsukura, S. (2001) Nature 409, 194-198
8. Tschop, M., Smiley, D. L., and Heiman, M. L. (2000) Nature 407, 908-913
9. Asakawa, A., Inui, A., Kaga, T., Yuzuriha, H., Nagata, T., Ueno, N., Makino, S., Fujimiya, M., Niijima, A., Fujino, M. A., and Kasuga, M. (2001) Gastroenterology 120, 337-345
10. Schwartz, M. W., Woods, S. C., Porte, D. J., Seeley, R. J., and Baskin, D. G. (2000) Nature 404, 661-671
11. Batterham, R. L., Cowley, M. A., Small, C. J., Herzog, H., Cohen, M. A., Dakin, C. L., Wren, A. M., Brynes, A. E., Low, M. J., Ghatei, M. A., Cone, R. D., and Bloom, S. R. (2002) Nature 418, 650-654
12. Tseng, C., Jarboe, L. A., and Wolfe, M. M. (1994) Am. J. Physiol. 266, G887-G891
13. Fehmann, H., Goke, R., and Goke, B. (1995) Endocrine Rev. 16, 390-410
14. Drucker, D. J. (1998) Diabetes 47, 159-169
15. Cataland, S., Crockett, S. E., Brown, J. C., and Mazzaferri, E. L. (1974) J. Clin. Endocrinol. Metabol. 39, 223-228
16. Sykes, S., Morgan, L. M., English, J., and Marks, V. (1980) J. Endocrinol. 85, 201-207
17. Wolfe, M. M., Zhao, K. B., Glazier, K. D., Jarboe, L. A., and Tseng, C. C. (2000) Am. J. Physiol. 279, G561-G566
18. Thomas, F. B., Mazzaferri, E. L., Crockett, S. E., Mekhjian, H. S., Gruemer, H. D., and Cataland, S. (1976) Gastroenterology 70, 523-527
19. Falko, J. M., Crockett, S. E., Cataland, S., and Mazzaferri, E. L. (1975) J. Clin. Endocrinol. Metabol. 41, 260-265
20. Bailey, C. J., Flatt, P. R., Kwasowski, P., Powell, C. J., and Marks, V. (1986) Acta Endocrinol. (Copenh) 112, 224-229
21. Miyawaki, K., Yamada, Y., Ban, N., Ihara, Y., Tsukiyama, K., Zhou, H., Fujimoto, S., Oku, A., Tsuda, K., Toyokuni, S., Hiai, H., Mizunoya, W., Fushiki, T., Holst, J. J., Makino, M., Tashita, A., Kobara, Y., Tsubamoto, Y., Jinnouchi, T., Jomori, T., and Seino, Y. (2002) Nat. Med. 8, 738-742
22. Yip, R. G., Boylan, M. O., Kieffer, T. J., and Wolfe, M. M. (1998) Endocrinology 139, 4004-4007
23. Hauner, H., Glatting, G., Kaminska, D., and Pfeiffer, E. F. (1988) Ann. Nutr. Metab. 32, 282-288
24. Starich, G. H., Bar, R. S., and Mazzaferri, E. L. (1985) Am. J. Physiol. 249, E603-E607
25. Eckel, R. H., Fujimoto, W. Y., and Brunzell, J. D. (1979) Diabetes 28, 1141-1142
26. Knapper, J. M., Puddicombe, S. M., Morgan, L. M., Fletcher, J. M., and Marks, V. (1993) Biochem. Soc. Trans. 21, 135S
27. Wasada, T., McCorkle, K., Harris, V., Kawai, K., Howard, B., and Unger, R. H. (1981) J. Clin. Invest. 68, 1106-1107
28. Ebert, R., Nauck, M., and Creutzfeldt, W. (1991) Horm. Metab. Res. 23, 517-521
29. Beck, B., Max, J. P., and Villaume, C. (1988) Int. J. Obes. 12, 41-47
30. Oben, J., Morgan, L., Fletcher, J., and Marks, V. (1991) J. Endocrinol. 130, 267-272
31. Baba, A. S., Harper, J. M., and Buttery, P. J. (2000) Comp. Biochem. Physiol. B Biochem. Mol. Biol. 127, 173-182
32. Salera, M., Giacomoni, P., Pironi, L., Cornia, G., Capelli, M., Marini, A., Benfenati, F., Miglioli, M., and Barbara, L. (1982) J. Clin. Endocrinol. Metab. 55, 329-336
33. Morgan, L. M., Hampton, S. M., Tredger, J. A., Cramb, R., and Marks, V. (1988) Br. J. Nutr. 59, 373-380
34. Elahi, D., Andersen, D. K., Muller, D. C., Tobin, J. D., Brown, J. C., and Andres, R. (1984) Diabetes 33, 950-957
35. Creutzfeldt, W., Ebert, R., Willms, B., Frerichs, H., and Brown, J. C. (1978) Diabetologia 14, 15-24
36. Ebert, R., Frerichs, H., and Creutzfeldt, W. (1979) Eur J. Clin. Invest. 9, 129-135
37. Drucker, D. J. (2007) J. Clin. Invest. 117, 24-32
38. Miyawaki, K., Yamada, Y., Yano, H., Niwa, H., Ban, N., Ihara, Y., Kubota, A., Fujimoto, S., Kajikawa, M., Kuroe, A., Tsuda, K., Hashimoto, H., Yamashita, T., Jomori, T., Tashiro, F., Miyazaki, J., and Seino, Y. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 14843-14847
39. Pamir, N., Lynn, F. C., Buchan, A. M., Ehses, J., Hinke, S. A., Pospisilik, J. A., Miyawaki, K., Yamada, Y., Seino, Y., McIntosh, C. H., and Pederson, R. A. (2003) Am. J. Physiol. Endocrinol. Metab. 284, E931-E939
40. Ramshur, E. B., Rull, T. R., and Wice, B. M. (2002) J. Cell. Physiol. 192, 339-350
41. Wang, S. Y., Chi, M. M., Li, L., Moley, K. H., and Wice, B. M. (2003) Am. J. Physiol. Endocrinol. 284, E988-E1000
42. Wang, S. Y., Liu, J., Li, L., and Wice, B. M. (2004) J. Histochem. Cytochem. 52, 53-63
43. Li, L., and Wice, B. M. (2005) Am. J. Physiol. Endocrinol. Metab. 288, E208-E215
44. Anlauf, M., Weihe, E., Hartschuh, W., Hamscher, G., and Feurle, G. E. (2000) J. Histochem. Cytochem. 48, 1617-1626
45. Silvestre, R. A., Rodriguez-Gallardo, J., Egido, E. M., Hernandez, R., and Marco, J. (2003) Regul. Pept. 115, 25-29
46. Feurle, G. E. (1998) Peptides 19, 609-615
47. Feurle, G. E., Hamscher, G., Kusiek, R., Meyer, H. E., and Metzger, J. W. (1992) J. Biol. Chem. 267, 22305-22309
48. Feurle, G. E., Heger, M., Niebergall-Roth, E., Teyssen, S., Fried, M., Eberle, C., Singer, M. V., and Hamscher, G. (1997) J. Pept. Res. 49, 324-330
49. Heuser, M., Kleiman, I., Popken, O., Nustede, R., and Post, S. (2002) Regul. Pept. 107, 23-27
50. Higashimoto, Y., and Liddle, R. A. (1993) Biochem. Biophys. Res. Commun. 193, 182-190
51. Maxwell, F., Maxwell, I. H., and Glode, L. M. (1987) Mol. Cell Biol. 7, 1576-1579
52. Wice, B. M., and Gordon, J. I. (1998) J. Biol. Chem. 273, 25310-25319
53. Preitner, F., Ibberson, M., Franklin, I., Binnert, C., Pende, M., Gjinovci, A., Hansotia, T., Drucker, D. J., Wollheim, C., Burcelin, R., and Thorens, B. (2004) J. Clin. Invest. 113, 635-645
54. Cani, P. D., Holst, J. J., Drucker, D. J., Delzenne, N. M., Thorens, B., Burcelin, R., and Knauf, C. (2007) Mol. Cell Endocrinol. 276, 18-23
55. Hansotia, T., Maida, A., Flock, G., Yamada, Y., Tsukiyama, K., Seino, Y., and Drucker, D. J. (2007) J. Clin. Invest. 117, 143-152
56. Abbott, C. R., Small, C. J., Sajedi, A., Smith, K. L., Parkinson, J. R., Broadhead, L. L., Ghatei, M. A., and Bloom, S. R. (2006) Int. J. Obes. (Lond.) 30, 288-292
57. Jandacek, R. J., Heubi, J. E., and Tso, P. (2004) Gastroenterology 127, 139-144
58. Persson, K., Gingerich, R. L., Nayak, S., Wada, K., Wada, E., and Ahren, B. (2000) Am. J. Physiol. 279, E956-E962
59. Lu, W. J., Yang, Q., Sun, W., Woods, S. C., D'Alessio, D., and Tso, P. (2007) Am. J. Physiol. 293, G963-G971
60. Cheung, A. T., Dayanandan, B., Lewis, J. T., Korbutt, G. S., Rajotte, R. V., Bryer-Ash, M., Boylan, M. O., Wolfe, M. M., and Kieffer, T. J. (2000) Science 290, 1959-1962
61. Breitman, M. L., Bryce, D. M., Giddens, E., Clapoff, S., Goring, D., Tsui, L. C., Klintworth, G. K., and Bernstein, A. (1989) Development 106, 457-463
62. Breitman, M. L., Rombola, H., Maxwell, I. H., Klintworth, G. K., and Bernstein, A. (1990) Mol. Cell Biol. 10, 474-479
63. Palmiter, R. D., Behringer, R. R., Quaife, C. J., Maxwell, F., Maxwell, I. H., and Brinster, R. L. (1987) Cell 50, 435-443
64. Garabedian, E. M., Roberts, L. J., McNevin, M. S., and Gordon, J. I. (1997) J. Biol. Chem. 272, 23729-23740
65. Itoh, H., Beck, P. L., Inoue, N., Xavier, R., and Podolsky, D. K. (1999) J. Clin. Invest. 104, 1539-1547
66. Liddle, R. A. (1997) Annu. Rev. Physiol. 59, 221-242
67. Theodorakis, M. J., Carlson, O., Michopoulos, S., Doyle, M. E., Juhaszova, M., Petraki, K., and Egan, J. M. (2006) Am. J. Physiol. 290, E550-E559
68. Mortensen, K., Christensen, L. L., Holst, J. J., and Orskov, C. (2003) Regul. Pept. 114, 189-196
69. Tseng, C., Boylan, M. O., Jarboe, L. A., Williams, E. K., Sunday, M. E., and Wolfe, M. M. (1995) Mol. Cell. Endocrinol. 115, 13-19
70. Zhou, L., Nian, M., Gu, J., and Irwin, D. M. (2006) Am. J. Physiol. 290, R634-R641
71. Hamscher, G., Meyer, H. E., and Feurle, G. E. (1996) Peptides 17, 889-893
72. Feurle, G. E., Ikonomu, S., Partoulas, G., Stoschus, B., and Hamscher, G. (2003) Regul. Pept. 111, 153-159