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Volumn 154, Issue 10, 2013, Pages 3552-3564

GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; SHORT CHAIN FATTY ACID; SUBSTANCE P;

EID: 84884693129     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1142     Document Type: Article
Times cited : (462)

References (49)
  • 2
    • 0019807278 scopus 로고
    • The diffuse endocrine-paracrine system of the gut in health and disease: Ultrastructural features
    • Solcia E, Capella C, Buffa R, et al. The diffuse endocrine-paracrine system of the gut in health and disease: ultrastructural features. Scand J Gastroenterol Suppl. 1981;70:25-36. (Pubitemid 12166289)
    • (1981) Scandinavian Journal of Gastroenterology, Supplement , vol.16 , Issue.SUPPL. 70 , pp. 25-36
    • Solcia, E.1    Capella, C.2    Buffa, R.3
  • 3
    • 56749154840 scopus 로고    scopus 로고
    • A gut feeling for obesity: 7TM sensors on enteroendocrine cells
    • Engelstoft MS, Egerod KL, Holst B, Schwartz TW. A gut feeling for obesity: 7TM sensors on enteroendocrine cells. Cell Metab. 2008;8:447-449.
    • (2008) Cell Metab , vol.8 , pp. 447-449
    • Engelstoft, M.S.1    Egerod, K.L.2    Holst, B.3    Schwartz, T.W.4
  • 4
    • 0018681487 scopus 로고
    • Somatostatin cell processes as pathways for paracrine secretion
    • Larsson LI, Goltermann N, de Magistris L, Rehfeld JF, Schwartz TW. Somatostatin cell processes as pathways for paracrine secretion. Science. 1979;205:1393-1395. (Pubitemid 10226649)
    • (1979) Science , vol.205 , Issue.4413 , pp. 1393-1395
    • Larsson, L.-I.1    Goltermann, N.2    De Magistris, L.3
  • 6
    • 77956803753 scopus 로고    scopus 로고
    • An enteroendocrine full package solution
    • Schwartz TW, Holst B. An enteroendocrine full package solution. Cell Metab. 2010;11:445-447.
    • (2010) Cell Metab , vol.11 , pp. 445-447
    • Schwartz, T.W.1    Holst, B.2
  • 8
    • 84862743498 scopus 로고    scopus 로고
    • Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry
    • Habib AM, Richards P, Cairns LS, et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology. 2012;153:3054-3065.
    • (2012) Endocrinology , vol.153 , pp. 3054-3065
    • Habib, A.M.1    Richards, P.2    Cairns, L.S.3
  • 9
    • 84870225450 scopus 로고    scopus 로고
    • A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin
    • Egerod KL, Engelstoft MS, Grunddal KV, et al. A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin. Endocrinology. 2012;153:5782-5795.
    • (2012) Endocrinology , vol.153 , pp. 5782-5795
    • Egerod, K.L.1    Engelstoft, M.S.2    Grunddal, K.V.3
  • 12
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • Tremaroli V, Backhed F. Functional interactions between the gut microbiota and host metabolism. Nature. 2012;489:242-249.
    • (2012) Nature , vol.489 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 13
    • 0031893151 scopus 로고    scopus 로고
    • Contributions of microbes in vertebrate gastrointestinal tract to production and conservation of nutrients
    • Stevens CE, Hume ID. Contributions of microbes in vertebrate gastrointestinal tract to production and conservation of nutrients. Physiol Rev. 1998;78:393-427. (Pubitemid 28182899)
    • (1998) Physiological Reviews , vol.78 , Issue.2 , pp. 393-427
    • Stevens, C.E.1    Hume, I.D.2
  • 14
    • 0023276469 scopus 로고
    • Short chain fatty acids in human large intestine, portal, hepatic and venous blood
    • Cummings JH, Pomare EW, Branch WJ, Naylor CP, Macfarlane GT. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut. 1987;28:1221-1227. (Pubitemid 17156038)
    • (1987) Gut , vol.28 , Issue.10 , pp. 1221-1227
    • Cummings, J.H.1    Pomare, E.W.2    Branch, W.J.3    Naylor, C.P.E.4    Macfarlane, G.T.5
  • 15
    • 0022271951 scopus 로고
    • Contractile effect of short-chain fatty acids on the isolated colon of the rat
    • Yajima T. Contractile effect of short-chain fatty acids on the isolated colon of the rat. J Physiol. 1985;368:667-678. (Pubitemid 16192443)
    • (1985) Journal of Physiology , vol.VOL. 368 , pp. 667-678
    • Yajima, T.1
  • 16
    • 0023787620 scopus 로고
    • Luminal propionate-induced secretory response in the rat distal colon in vitro
    • Yajima T. Luminal propionate-induced secretory response in the rat distal colon in vitro. J Physiol. 1988;403:559-575.
    • (1988) J Physiol , vol.403 , pp. 559-575
    • Yajima, T.1
  • 17
    • 34547965812 scopus 로고    scopus 로고
    • Dietary non-digestible carbohydrates promote L-cell differentiation in the proximal colon of rats
    • DOI 10.1017/S0007114507691648, PII S0007114507691648
    • Cani PD, Hoste S, Guiot Y, Delzenne NM. Dietary non-digestible carbohydrates promote L-cell differentiation in the proximal colon of rats. Br J Nutr. 2007;98:32-37. (Pubitemid 47272144)
    • (2007) British Journal of Nutrition , vol.98 , Issue.1 , pp. 32-37
    • Cani, P.D.1    Hoste, S.2    Guiot, Y.3    Delzenne, N.M.4
  • 18
    • 84859587827 scopus 로고    scopus 로고
    • Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms
    • Lin HV, Frassetto A, Kowalik EJ Jr, et al. Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. PLoS One. 2012;7:e35240.
    • (2012) PLoS One , vol.7
    • Lin, H.V.1    Frassetto, A.2    Kowalik Jr., E.J.3
  • 20
    • 0026633897 scopus 로고
    • Propionate induces polymorphonuclear leukocyte activation and inhibits formylmethionyl-leucyl-phenylalanine-stimulated activation
    • Brunkhorst BA, Kraus E, Coppi M, Budnick M, Niederman R. Propionate induces polymorphonuclear leukocyte activation and inhibits formylmethionyl- leucyl-phenylalanine-stimulated activation. Infection Immun. 1992;60:2957-2968.
    • (1992) Infection Immun , vol.60 , pp. 2957-2968
    • Brunkhorst, B.A.1    Kraus, E.2    Coppi, M.3    Budnick, M.4    Niederman, R.5
  • 21
    • 0023805092 scopus 로고
    • Propionic acid-induced calcium mobilization in human neutrophils
    • Naccache PH, Faucher N, Caon AC, McColl SR. Propionic acid-induced calcium mobilization in human neutrophils. J Cell Physiol. 1988;136:118-124.
    • (1988) J Cell Physiol , vol.136 , pp. 118-124
    • Naccache, P.H.1    Faucher, N.2    Caon, A.C.3    McColl, S.R.4
  • 22
    • 0023147138 scopus 로고
    • Short-chain fatty acids produced by anaerobic bacteria alter the physiological responses of human neutrophils to chemotactic peptide
    • Eftimiadi C, Buzzi E, Tonetti M, et al. Short-chain fatty acids produced by anaerobic bacteria alter the physiological responses of humanneutrophils to chemotactic peptide. J Infect. 1987;14:43-53. (Pubitemid 17229219)
    • (1987) Journal of Infection , vol.14 , Issue.1 , pp. 43-53
    • Eftimiadi, C.1    Buzzi, E.2    Tonetti, M.3
  • 23
    • 0026614980 scopus 로고
    • Alteration of cytoplasmic Ca2+ in resting and stimulated human neutrophils by short-chain carboxylic acids at neutral pH
    • Nakao S, Fujii A, Niederman R. Alteration of cytoplasmic Ca2+ in resting and stimulated human neutrophils by short-chain carboxylic acids at neutral pH. Infect Immun. 1992;60:5307-5311.
    • (1992) Infect Immun , vol.60 , pp. 5307-5311
    • Nakao, S.1    Fujii, A.2    Niederman, R.3
  • 24
    • 73349123182 scopus 로고    scopus 로고
    • Gprotein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation
    • Sina C, Gavrilova O, Forster M, et al. Gprotein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation. J Immunol. 2009;183:7514-7522.
    • (2009) J Immunol , vol.183 , pp. 7514-7522
    • Sina, C.1    Gavrilova, O.2    Forster, M.3
  • 25
    • 70350666634 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
    • Maslowski KM, Vieira AT, Ng A, et al. Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature. 2009;461:1282-1286.
    • (2009) Nature , vol.461 , pp. 1282-1286
    • Maslowski, K.M.1    Vieira, A.T.2    Ng, A.3
  • 28
    • 0037453280 scopus 로고    scopus 로고
    • 2R, expressed on leukocytes and activated by short-chain fatty acids
    • DOI 10.1016/S0006-291X(03)00488-1
    • Nilsson NE, Kotarsky K, Owman C, Olde B. Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. Biochem Biophys Res Commun. 2003;303:1047-1052. (Pubitemid 36390250)
    • (2003) Biochemical and Biophysical Research Communications , vol.303 , Issue.4 , pp. 1047-1052
    • Nilsson, N.E.1    Kotarsky, K.2    Owman, C.3    Olde, B.4
  • 29
    • 79956348319 scopus 로고    scopus 로고
    • Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)
    • Kimura I, Inoue D, Maeda T, et al. Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41). Proc Natl Acad Sci USA. 2011;108:8030-8035.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 8030-8035
    • Kimura, I.1    Inoue, D.2    Maeda, T.3
  • 30
    • 0037307761 scopus 로고    scopus 로고
    • LSSIG is a novel murine leukocyte-specific GPCR that is induced by the activation of STAT3
    • DOI 10.1182/blood-2002-06-1881
    • Senga T, Iwamoto S, Yoshida T, et al. LSSIG is a novel murine leukocyte-specificGPCRthat is induced by the activation of STAT3. Blood. 2003;101:1185-1187. (Pubitemid 36139395)
    • (2003) Blood , vol.101 , Issue.3 , pp. 1185-1187
    • Senga, T.1    Iwamoto, S.2    Yoshida, T.3    Yokota, T.4    Adachi, K.5    Azuma, E.6    Hamaguchi, M.7    Iwamoto, T.8
  • 32
    • 55949091259 scopus 로고    scopus 로고
    • Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
    • Samuel BS, Shaito A, Motoike T, et al. Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41. Proc Natl Acad Sci USA. 2008;105:16767-16772.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16767-16772
    • Samuel, B.S.1    Shaito, A.2    Motoike, T.3
  • 33
    • 70149102106 scopus 로고    scopus 로고
    • Expression of short-chain fatty acid receptor GPR41 in the human colon
    • Tazoe H, Otomo Y, Karaki S, et al. Expression of short-chain fatty acid receptor GPR41 in the human colon. Biomed Res. 2009;30:149-156.
    • (2009) Biomed Res , vol.30 , pp. 149-156
    • Tazoe, H.1    Otomo, Y.2    Karaki, S.3
  • 34
    • 84864491110 scopus 로고    scopus 로고
    • Duodenal enteroendocrine I-cells contain mRNA transcripts encoding key endocannabinoid and fatty acid receptors
    • Sykaras AG, Demenis C, Case RM, McLaughlin JT, Smith CP. Duodenal enteroendocrine I-cells contain mRNA transcripts encoding key endocannabinoid and fatty acid receptors. PLoS One. 2012;7:e42373.
    • (2012) PLoS One , vol.7
    • Sykaras, A.G.1    Demenis, C.2    Case, R.M.3    McLaughlin, J.T.4    Smith, C.P.5
  • 35
    • 84874395887 scopus 로고    scopus 로고
    • Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets
    • Ulven T. Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets. Front Endocrinol (Lausanne). 2012;3:111.
    • (2012) Front Endocrinol (Lausanne) , vol.3 , pp. 111
    • Ulven, T.1
  • 36
    • 84856509724 scopus 로고    scopus 로고
    • Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2
    • Tolhurst G, Heffron H, Lam YS, et al. Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes. 2012;61:364-371.
    • (2012) Diabetes , vol.61 , pp. 364-371
    • Tolhurst, G.1    Heffron, H.2    Lam, Y.S.3
  • 38
    • 0033559118 scopus 로고    scopus 로고
    • Rapid modification of bacterial artificial chromosomes by ET-recombination
    • DOI 10.1093/nar/27.6.1555
    • Muyrers JP, Zhang Y, Testa G, Stewart AF. Rapid modification of bacterial artificial chromosomes by ET-recombination. Nucleic Acids Res. 1999;27:1555-1557. (Pubitemid 29206301)
    • (1999) Nucleic Acids Research , vol.27 , Issue.6 , pp. 1555-1557
    • Muyrers, J.P.P.1    Zhang, Y.2    Testa, G.3    Stewart, A.F.4
  • 39
    • 77950261397 scopus 로고    scopus 로고
    • An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81
    • Ahmed K, Tunaru S, Sassmann A, et al. An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81. Cell Metab. 2010;11:311-319.
    • (2010) Cell Metab , vol.11 , pp. 311-319
    • Ahmed, K.1    Tunaru, S.2    Sassmann, A.3
  • 40
    • 84884687479 scopus 로고    scopus 로고
    • GPR41 and modulators thereof for the treatment of insulin-related disorders
    • PCT Int. Appl. WO 2006052566
    • Boatman PD, Bruce MA, Chu ZL, Leonard JN. GPR41 and modulators thereof for the treatment of insulin-related disorders. PCT Int. Appl. WO 2006052566. 2006.
    • (2006)
    • Boatman, P.D.1    Bruce, M.A.2    Chu, Z.L.3    Leonard, J.N.4
  • 41
    • 84861058085 scopus 로고    scopus 로고
    • LPS counter regulates RNA expression of extracellular proteases and their inhibitors in murine macrophages
    • Hald A, Rono B, Lund LR, Egerod KL. LPS counter regulates RNA expression of extracellular proteases and their inhibitors in murine macrophages. Mediators Inflamm. 2012;2012:157894.
    • (2012) Mediators Inflamm , vol.2012 , pp. 157894
    • Hald, A.1    Rono, B.2    Lund, L.R.3    Egerod, K.L.4
  • 43
    • 0032504227 scopus 로고    scopus 로고
    • Functional characterization of a series of mutant G protein α(q) subunits displaying promiscuous receptor coupling properties
    • DOI 10.1074/jbc.273.28.17886
    • Kostenis E, Zeng FY, Wess J. Functional characterization of a series of mutant G protein αq subunits displaying promiscuous receptor coupling properties. J Biol Chem. 1998;273:17886-17892. (Pubitemid 28355136)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.28 , pp. 17886-17892
    • Kostenis, E.1    Zeng, F.-Y.2    Wess, J.3
  • 45
    • 80051538014 scopus 로고    scopus 로고
    • Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine
    • Poole DP, Pelayo JC, Cattaruzza F, et al. Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine. Gastroenterology. 2011;141:565-575, 575 e561-564.
    • (2011) Gastroenterology , vol.141
    • Poole, D.P.1    Pelayo, J.C.2    Cattaruzza, F.3
  • 47
    • 67349157517 scopus 로고    scopus 로고
    • Characterization of a novel ghrelin cell reporter mouse
    • Sakata I, Nakano Y, Osborne-Lawrence S, et al. Characterization of a novel ghrelin cell reporter mouse. Regul Peptides. 2009;155:91-98.
    • (2009) Regul Peptides , vol.155 , pp. 91-98
    • Sakata, I.1    Nakano, Y.2    Osborne-Lawrence, S.3
  • 48
    • 79954435406 scopus 로고    scopus 로고
    • Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide
    • Kaji I, Karaki SI, Tanaka R, Kuwahara A. Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide. J Mol Histol. 2011;42(1):27-38.
    • (2011) J Mol Histol , vol.42 , Issue.1 , pp. 27-38
    • Kaji, I.1    Karaki, S.I.2    Tanaka, R.3    Kuwahara, A.4
  • 49
    • 84861196704 scopus 로고    scopus 로고
    • Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation
    • Inoue D, Kimura I, Wakabayashi M, et al. Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation. FEBS Lett. 2012;586:1547-1554.
    • (2012) FEBS Lett , vol.586 , pp. 1547-1554
    • Inoue, D.1    Kimura, I.2    Wakabayashi, M.3


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