WW domains of the yes-kinase-associated-protein (YAP) transcriptional regulator behave as independent units with different binding preferences for PPxY motif-containing ligands

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Iglesias Bexiga, Manuel ^a,c   Castillo, Francisco ^a   Cobos, Eva S ^a   Oka, Tsutomu ^b   Sudol, Marius ^b   Luque, Irene ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b WEIS CENTER FOR RESEARCH   (United States)

^c INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; LATS KINASE; LIGAND; PHOSPHOTRANSFERASE; PROTEIN PATCHED 1; REGULATOR PROTEIN; TRYPTOPHAN; UNCLASSIFIED DRUG; YES KINASE ASSOCIATED PROTEIN; CELL SURFACE RECEPTOR; LATS1 PROTEIN, HUMAN; PATCHED RECEPTORS; PEPTIDE; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

ARTICLE; BIOPHYSICS; CALORIMETRY; CONTROLLED STUDY; PHAGE DISPLAY; PPXY MOTIF; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING; SIGNAL TRANSDUCTION; STATIC ELECTRICITY; CHEMISTRY; GENETICS; METABOLISM; PROTEIN TERTIARY STRUCTURE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID MOTIFS; LIGANDS; PEPTIDES; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, CELL SURFACE;

EID: 84954481183     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113828     Document Type: Article

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