-
1
-
-
70350780570
-
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways
-
Alarcon C, Zaromytidou AI, Xi Q, Gao S, Yu J, et al. Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell. 2009;139:757-69.
-
(2009)
Cell
, vol.139
, pp. 757-769
-
-
Alarcon, C.1
Zaromytidou, A.I.2
Xi, Q.3
Gao, S.4
Yu, J.5
-
2
-
-
33751253145
-
Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain
-
Anbanandam A, Albarado DC, Nguyen CT, Halder G, Gao X, et al. Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain. Proc Natl Acad Sci U S A. 2006;103:17225-30.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17225-17230
-
-
Anbanandam, A.1
Albarado, D.C.2
Nguyen, C.T.3
Halder, G.4
Gao, X.5
-
3
-
-
0028648838
-
WWP, a new amino acid motif present in single or multiple copies in various proteins including dystrophin and the SH3-binding Yes-associated protein YAP65
-
Andre B, Springael JY. WWP, a new amino acid motif present in single or multiple copies in various proteins including dystrophin and the SH3-binding Yes-associated protein YAP65. Biochem Biophys Res Commun. 1994;205:1201-5.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1201-1205
-
-
Andre, B.1
Springael, J.Y.2
-
4
-
-
79959640061
-
A Smad action turnover switch operated by WW domain readers of a phosphoserine code
-
Aragon E, Goerner N, Zaromytidou AI, Xi Q, Escobedo A, et al. A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev. 2011;25:1275-88.
-
(2011)
Genes Dev
, vol.25
, pp. 1275-1288
-
-
Aragon, E.1
Goerner, N.2
Zaromytidou, A.I.3
Xi, Q.4
Escobedo, A.5
-
5
-
-
33749334018
-
A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization
-
Aylon Y, Michael D, Shmueli A, Yabuta N, Nojima H, et al. A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. Genes Dev. 2006;20:2687-700.
-
(2006)
Genes Dev
, vol.20
, pp. 2687-2700
-
-
Aylon, Y.1
Michael, D.2
Shmueli, A.3
Yabuta, N.4
Nojima, H.5
-
6
-
-
78049435859
-
The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1
-
Aylon Y, Ofir-Rosenfeld Y, Yabuta N, Lapi E, Nojima H, et al. The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1. Genes Dev. 2010;24:2420-9.
-
(2010)
Genes Dev
, vol.24
, pp. 2420-2429
-
-
Aylon, Y.1
Ofir-Rosenfeld, Y.2
Yabuta, N.3
Lapi, E.4
Nojima, H.5
-
7
-
-
0037415643
-
The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density
-
Balda MS, Garrett MD, Matter K. The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density. J Cell Biol. 2003;160:423-32.
-
(2003)
J Cell Biol
, vol.160
, pp. 423-432
-
-
Balda, M.S.1
Garrett, M.D.2
Matter, K.3
-
8
-
-
0037249343
-
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73 mediated apoptosis
-
Basu S, Totty NF, Irwin MS, Sudol M, Downward J. Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73 mediated apoptosis. Mol Cell. 2003;11:11-23.
-
(2003)
Mol Cell
, vol.11
, pp. 11-23
-
-
Basu, S.1
Totty, N.F.2
Irwin, M.S.3
Sudol, M.4
Downward, J.5
-
9
-
-
0027988814
-
The WW domain: A signalling site in dystrophin?
-
Bork P, Sudol M. The WW domain: a signalling site in dystrophin? Trends Biochem Sci. 1994;19:531-3.
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 531-533
-
-
Bork, P.1
Sudol, M.2
-
10
-
-
77957234538
-
Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq
-
Bottomly D, Kyler SL, McWeeney SK, Yochum GS. Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq. Nucleic Acids Res. 2010;38:5735-45.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 5735-5745
-
-
Bottomly, D.1
Kyler, S.L.2
McWeeney, S.K.3
Yochum, G.S.4
-
11
-
-
79953223677
-
Hippo pathway-independent restriction of TAZ and YAP by angiomotin
-
Chan SW, Lim CJ, Chong YF, Pobbati AV, Huang C, et al. Hippo pathway-independent restriction of TAZ and YAP by angiomotin. J Biol Chem. 2011;286:7018-26.
-
(2011)
J Biol Chem
, vol.286
, pp. 7018-7026
-
-
Chan, S.W.1
Lim, C.J.2
Chong, Y.F.3
Pobbati, A.V.4
Huang, C.5
-
12
-
-
0030858496
-
Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands
-
Chen HI, Einbond A, Kwak SJ, Linn H, Koepf E, et al. Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. J Biol Chem. 1997;272:17070-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 17070-17077
-
-
Chen, H.I.1
Einbond, A.2
Kwak, S.J.3
Linn, H.4
Koepf, E.5
-
13
-
-
0029099161
-
The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules
-
Chen HI, Sudol M. The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules. Proc Natl Acad Sci U S A. 1995;92:7819-23.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7819-7823
-
-
Chen, H.I.1
Sudol, M.2
-
14
-
-
79953145500
-
Structural and functional insights into the TEAD-YAP complex in the Hippo signaling pathway
-
Chen L, Loh PG, Song H. Structural and functional insights into the TEAD-YAP complex in the Hippo signaling pathway. Protein Cell. 2010;1:1073-83.
-
(2010)
Protein Cell
, vol.1
, pp. 1073-1083
-
-
Chen, L.1
Loh, P.G.2
Song, H.3
-
15
-
-
84861986053
-
Wnt/beta-catenin signaling and disease
-
Clevers H, Nusse R. Wnt/beta-catenin signaling and disease. Cell. 2012;149:1192-205.
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
16
-
-
37349005990
-
Yes-associated protein (YAP) is a critical mediator of c-Jun-dependent apoptosis
-
Danovi SA, Rossi M, Gudmundsdottir K, Yuan M, Melino G, et al. Yes-associated protein (YAP) is a critical mediator of c-Jun-dependent apoptosis. Cell Death Differ. 2008;15:217-9.
-
(2008)
Cell Death Differ
, vol.15
, pp. 217-219
-
-
Danovi, S.A.1
Rossi, M.2
Gudmundsdottir, K.3
Yuan, M.4
Melino, G.5
-
17
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, et al. Role of YAP/TAZ in mechanotransduction. Nature. 2011;474:179-83.
-
(2011)
Nature
, vol.474
, pp. 179-183
-
-
Dupont, S.1
Morsut, L.2
Aragona, M.3
Enzo, E.4
Giulitti, S.5
-
18
-
-
0029915066
-
Towards prediction of cognate complexes between the WW domain and proline-rich ligands
-
Einbond A, Sudol M. Towards prediction of cognate complexes between the WW domain and proline-rich ligands. FEBS Lett. 1996;384:1-8.
-
(1996)
FEBS Lett
, vol.384
, pp. 1-8
-
-
Einbond, A.1
Sudol, M.2
-
19
-
-
80054912552
-
Deciphering tumor-suppressor signaling in fl ies: Genetic link between Scribble/Dlg/Lgl and the Hippo pathways
-
Enamoto M, Igaki T. Deciphering tumor-suppressor signaling in fl ies: genetic link between Scribble/Dlg/Lgl and the Hippo pathways. J Genet Genomics. 2011;38:461-70.
-
(2011)
J Genet Genomics
, vol.38
, pp. 461-470
-
-
Enamoto, M.1
Igaki, T.2
-
20
-
-
0035957958
-
Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains
-
Espanel X, Sudol M. Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains. J Biol Chem. 2001;276:14514-23.
-
(2001)
J Biol Chem
, vol.276
, pp. 14514-14523
-
-
Espanel, X.1
Sudol, M.2
-
21
-
-
0037173716
-
Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling
-
Ferrigno O, Lallemand F, Verrecchia F, L'Hoste S, Camonis J, et al. Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling. Oncogene. 2002;21:4879-84.
-
(2002)
Oncogene
, vol.21
, pp. 4879-4884
-
-
Ferrigno, O.1
Lallemand, F.2
Verrecchia, F.3
L'Hoste, S.4
Camonis, J.5
-
22
-
-
33749547958
-
The tyrosine kinase c-Abl protects c-Jun from ubiquitination-mediated degradation in T cells
-
Gao B, Lee SM, Fang D. The tyrosine kinase c-Abl protects c-Jun from ubiquitination-mediated degradation in T cells. J Biol Chem. 2006;281:29711-8.
-
(2006)
J Biol Chem
, vol.281
, pp. 29711-29718
-
-
Gao, B.1
Lee, S.M.2
Fang, D.3
-
23
-
-
34047250808
-
RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network
-
Guo C, Tommasi S, Liu L, Yee JK, Dammann R, et al. RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network. Curr Biol. 2007;17:700-5.
-
(2007)
Curr Biol
, vol.17
, pp. 700-705
-
-
Guo, C.1
Tommasi, S.2
Liu, L.3
Yee, J.K.4
Dammann, R.5
-
24
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-74.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
25
-
-
41949138130
-
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
-
Hao Y, Chun A, Cheung K, Rashidi B, Yang X. Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem. 2008;283:5496-509.
-
(2008)
J Biol Chem
, vol.283
, pp. 5496-5509
-
-
Hao, Y.1
Chun, A.2
Cheung, K.3
Rashidi, B.4
Yang, X.5
-
26
-
-
79955405757
-
Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size
-
Heallen T, Zhang M, Wang J, Bonilla-Claudio M, Klysik E, et al. Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size. Science. 2011;332: 458-61.
-
(2011)
Science
, vol.332
, pp. 458-461
-
-
Heallen, T.1
Zhang, M.2
Wang, J.3
Bonilla-Claudio, M.4
Klysik, E.5
-
27
-
-
0028831959
-
The rsp5-domain is shared by proteins of diverse functions
-
Hofmann K, Bucher P. The rsp5-domain is shared by proteins of diverse functions. FEBS Lett. 1995;358:153-7.
-
(1995)
FEBS Lett
, vol.358
, pp. 153-157
-
-
Hofmann, K.1
Bucher, P.2
-
28
-
-
84866621687
-
The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway
-
Hong W, Guan KL. The YAP and TAZ transcription co-activators: key downstream effectors of the mammalian Hippo pathway. Semin Cell Dev Biol. 2012;23:785-93.
-
(2012)
Semin Cell Dev Biol
, vol.23
, pp. 785-793
-
-
Hong, W.1
Guan, K.L.2
-
29
-
-
0037097982
-
JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiledcoil-mediated interaction
-
Hu YF, Li R. JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiledcoil-mediated interaction. Genes Dev. 2002;16:1509-17.
-
(2002)
Genes Dev
, vol.16
, pp. 1509-1517
-
-
Hu, Y.F.1
Li, R.2
-
30
-
-
84876926465
-
YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14
-
Jun 11 [Epub ahead of print]
-
Huang JM, Nagatomo I, Suzuki E, Mizuno T, Kumagai T, et al. YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14. Oncogene. 2012. Jun 11 [Epub ahead of print]
-
(2012)
Oncogene
-
-
Huang, J.M.1
Nagatomo, I.2
Suzuki, E.3
Mizuno, T.4
Kumagai, T.5
-
31
-
-
84858002052
-
A molecular mechanism that links Hippo signaling to the inhibition of Wnt/beta-catenin signaling
-
Imajo M, Miyyatake K, Iimura A, Miyamoto A, Nishida E. A molecular mechanism that links Hippo signaling to the inhibition of Wnt/beta-catenin signaling. EMBO J. 2012;31:1109-22.
-
(2012)
EMBO J
, vol.31
, pp. 1109-1122
-
-
Imajo, M.1
Miyyatake, K.2
Iimura, A.3
Miyamoto, A.4
Nishida, E.5
-
32
-
-
17744380191
-
TAZ: A novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
-
Kanai F, Marignani PA, Sarbassova D, Yagi R, Hall RA, et al. TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. EMBO J. 2000;19:6778-91.
-
(2000)
EMBO J
, vol.19
, pp. 6778-6791
-
-
Kanai, F.1
Marignani, P.A.2
Sarbassova, D.3
Yagi, R.4
Hall, R.A.5
-
33
-
-
0042858208
-
WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
-
Komuro A, Nagai M, Navin NE, Sudol M. WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J Biol Chem. 2003;278:33334-41.
-
(2003)
J Biol Chem
, vol.278
, pp. 33334-33341
-
-
Komuro, A.1
Nagai, M.2
Navin, N.E.3
Sudol, M.4
-
34
-
-
84859516537
-
Wnt/beta-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells
-
Konsavage Jr WM, Kyler SL, Rennoll SA, Jin G, Yochum GS. Wnt/beta-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells. J Biol Chem. 2012;287:11730-9.
-
(2012)
J Biol Chem
, vol.287
, pp. 11730-11739
-
-
Konsavage, W.M.1
Kyler, S.L.2
Rennoll, S.A.3
Jin, G.4
Yochum, G.S.5
-
35
-
-
0037462927
-
Characterization of KIBRA, a novel WW domain-containing protein
-
Kremerskothen J, Plaas C, Buther K, Finger I, Veltel S, et al. Characterization of KIBRA, a novel WW domain-containing protein. Biochem Biophys Res Commun. 2003;300:862-7.
-
(2003)
Biochem Biophys Res Commun
, vol.300
, pp. 862-867
-
-
Kremerskothen, J.1
Plaas, C.2
Buther, K.3
Finger, I.4
Veltel, S.5
-
36
-
-
79953310106
-
Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF
-
Lai D, Ho KC, Hao Y, Yang X. Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Res. 2011;71:2728-38.
-
(2011)
Cancer Res
, vol.71
, pp. 2728-2738
-
-
Lai, D.1
Ho, K.C.2
Hao, Y.3
Yang, X.4
-
37
-
-
38949123978
-
Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage
-
Levy D, Adamovich Y, Reuven N, Shaul Y. Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage. Mol Cell. 2008;29:350-61.
-
(2008)
Mol Cell
, vol.29
, pp. 350-361
-
-
Levy, D.1
Adamovich, Y.2
Reuven, N.3
Shaul, Y.4
-
38
-
-
76149138881
-
Structural insights into the YAP and TEAD complex
-
Li Z, Zhao B, Wang P, Chen F, Dong Z, et al. Structural insights into the YAP and TEAD complex. Genes Dev. 2010;24:235-40.
-
(2010)
Genes Dev
, vol.24
, pp. 235-240
-
-
Li, Z.1
Zhao, B.2
Wang, P.3
Chen, F.4
Dong, Z.5
-
39
-
-
80052684667
-
Tyrosine phosphorylation of transcriptional coactivator WW-domain binding protein 2 regulates estrogen receptor alpha function in breast cancer via the Wnt pathway
-
Lim SK, Orhant-Prioux M, Toy W, Tan KY, Lim YP. Tyrosine phosphorylation of transcriptional coactivator WW-domain binding protein 2 regulates estrogen receptor alpha function in breast cancer via the Wnt pathway. FASEB J. 2011;9:3004-18.
-
(2011)
FASEB J
, vol.9
, pp. 3004-3018
-
-
Lim, S.K.1
Orhant-Prioux, M.2
Toy, W.3
Tan, K.Y.4
Lim, Y.P.5
-
40
-
-
77950626836
-
MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties
-
Liu AM, Poon RT, Luk JM. MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties. Biochem Biophys Res Commun. 2010;394:623-7.
-
(2010)
Biochem Biophys Res Commun
, vol.394
, pp. 623-627
-
-
Liu, A.M.1
Poon, R.T.2
Luk, J.M.3
-
41
-
-
84874788083
-
PTPN14 interacts with and negatively regulates the oncogenic function of YAP
-
Apr 23. Epub ahead of print
-
Liu X, Yang N, Figel SA, Wilson KE, Morrison CD, et al. PTPN14 interacts with and negatively regulates the oncogenic function of YAP. Oncogene. 2012;Apr 23. Epub ahead of print.
-
(2012)
Oncogene
-
-
Liu, X.1
Yang, N.2
Figel, S.A.3
Wilson, K.E.4
Morrison, C.D.5
-
42
-
-
84862605178
-
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
-
Liu-Chittenden Y, Huang B, Shim JS, Chen Q, Lee SJ, et al. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev. 2012;26:1300-5.
-
(2012)
Genes Dev
, vol.26
, pp. 1300-1305
-
-
Liu-Chittenden, Y.1
Huang, B.2
Shim, J.S.3
Chen, Q.4
Lee, S.J.5
-
43
-
-
0029775570
-
Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide
-
Macias MJ, Hyvonen M, Baraldi E, Schultz J, Sudol M, et al. Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide. Nature. 1996;382:646-9.
-
(1996)
Nature
, vol.382
, pp. 646-649
-
-
Macias, M.J.1
Hyvonen, M.2
Baraldi, E.3
Schultz, J.4
Sudol, M.5
-
44
-
-
0031685620
-
TGF-beta signal transduction
-
Massague J. TGF-beta signal transduction. Annu Rev Biochem. 1998;67:753-91.
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
45
-
-
84859583470
-
Integrating developmental signals: A Hippo in the (path) way
-
Mauviel A, Nallet-Staub F, Varelas X. Integrating developmental signals: a Hippo in the (path) way. Oncogene. 2012;31:1743-56.
-
(2012)
Oncogene
, vol.31
, pp. 1743-1756
-
-
Mauviel, A.1
Nallet-Staub, F.2
Varelas, X.3
-
46
-
-
80555131518
-
Epithelial organization, cell polarity and tumorigenesis
-
McCaffrey LM, Macara IG. Epithelial organization, cell polarity and tumorigenesis. Trends Cell Biol. 2011;21:727-35.
-
(2011)
Trends Cell Biol
, vol.21
, pp. 727-735
-
-
McCaffrey, L.M.1
Macara, I.G.2
-
47
-
-
85193176940
-
Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions
-
Jun 4 [Epub ahead of print]
-
Mihlan S, Reiss C, Thalheimer P, Herterich S, Gaetzner S, et al. Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions. Oncogene. 2012. Jun 4 [Epub ahead of print]
-
(2012)
Oncogene
-
-
Mihlan, S.1
Reiss, C.2
Thalheimer, P.3
Herterich, S.4
Gaetzner, S.5
-
48
-
-
0033571594
-
Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50
-
Mohler PJ, Kreda SM, Boucher RC, Sudol M, Stutts MJ, et al. Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50. J Cell Biol. 1999;147:879-90.
-
(1999)
J Cell Biol
, vol.147
, pp. 879-890
-
-
Mohler, P.J.1
Kreda, S.M.2
Boucher, R.C.3
Sudol, M.4
Stutts, M.J.5
-
49
-
-
79952304497
-
YAP is a candidate oncogene for esophageal squamous cell carcinoma
-
Muramatsu T, Imoto I, Matsui T, Kozaki K, Haruki S, et al. YAP is a candidate oncogene for esophageal squamous cell carcinoma. Carcinogenesis. 2011;32:389-98.
-
(2011)
Carcinogenesis
, vol.32
, pp. 389-398
-
-
Muramatsu, T.1
Imoto, I.2
Matsui, T.3
Kozaki, K.4
Haruki, S.5
-
50
-
-
0033617369
-
Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells
-
Ogata M, Takada T, Mori Y, Oh-hora M, Uchida Y, et al. Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells. J Biol Chem. 1999a;274:12905-9.
-
(1999)
J Biol Chem
, vol.274
, pp. 12905-12909
-
-
Ogata, M.1
Takada, T.2
Mori, Y.3
Oh-Hora, M.4
Uchida, Y.5
-
51
-
-
0033575321
-
Regulation of phosphorylation level and distribution of PTP36, a putative protein tyrosine phosphatase, by cell-substrate adhesion
-
Ogata M, Takada T, Mori Y, Uchida Y, Miki T, et al. Regulation of phosphorylation level and distribution of PTP36, a putative protein tyrosine phosphatase, by cell-substrate adhesion. J Biol Chem. 1999b;274:20717-24.
-
(1999)
J Biol Chem
, vol.274
, pp. 20717-20724
-
-
Ogata, M.1
Takada, T.2
Mori, Y.3
Uchida, Y.4
Miki, T.5
-
52
-
-
55549098921
-
Mst2 and Lats kinases regulate apoptotic function of YAP
-
Oka T, Mazack V, Sudol M. Mst2 and Lats kinases regulate apoptotic function of YAP. J Biol Chem. 2008;283:27534-46.
-
(2008)
J Biol Chem
, vol.283
, pp. 27534-27546
-
-
Oka, T.1
Mazack, V.2
Sudol, M.3
-
53
-
-
65449154339
-
Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZbinding motif
-
Oka T, Sudol M. Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZbinding motif. Genes Cells. 2009;14:607-15.
-
(2009)
Genes Cells
, vol.14
, pp. 607-615
-
-
Oka, T.1
Sudol, M.2
-
54
-
-
78649892579
-
Functional complex between YAP2 and ZO-2 is PDZ domain dependent, regulates YAP2 nuclear localization and signaling
-
Oka T, Remue E, Meerschaert K, Vanloo B, Boucherie C, Gfeller D, et al. Functional complex between YAP2 and ZO-2 is PDZ domain dependent, regulates YAP2 nuclear localization and signaling. Biochem J. 2010;432:461-72.
-
(2010)
Biochem J
, vol.432
, pp. 461-472
-
-
Oka, T.1
Remue, E.2
Meerschaert, K.3
Vanloo, B.4
Boucherie, C.5
Gfeller, D.6
-
55
-
-
84855344741
-
Opposing roles of angiomotin-like-1 and zona occludens-2 on proapoptotic function of YAP
-
Oka T, Schmitt AP, Sudol M. Opposing roles of angiomotin-like-1 and zona occludens-2 on proapoptotic function of YAP. Oncogene. 2012;31:128-34.
-
(2012)
Oncogene
, vol.31
, pp. 128-134
-
-
Oka, T.1
Schmitt, A.P.2
Sudol, M.3
-
56
-
-
77957883342
-
The hippo signaling pathway in development and cancer
-
Pan D. The hippo signaling pathway in development and cancer. Dev Cell. 2010;19:491-505.
-
(2010)
Dev Cell
, vol.19
, pp. 491-505
-
-
Pan, D.1
-
57
-
-
80053363788
-
Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor
-
Paramasivam M, Sarkeshik A, Yates 3rd JR, Fernandes MJ, McCollum D. Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor. Mol Biol Cell. 2011;22:3725-33.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3725-3733
-
-
Paramasivam, M.1
Sarkeshik, A.2
Yates Iii, J.R.3
Fernandes, M.J.4
McCollum, D.5
-
58
-
-
0842346438
-
Specificity in signal transduction: From phosphotyrosine-SH2 domain interactions to complex cellular systems
-
Pawson T. Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems. Cell. 2004;116:191-203.
-
(2004)
Cell
, vol.116
, pp. 191-203
-
-
Pawson, T.1
-
59
-
-
84857993243
-
Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation
-
Poernbacher I, Baumgartner R, Marada SK, Edwards K, Stocker H. Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation. Curr Biol. 2012;22:389-96.
-
(2012)
Curr Biol
, vol.22
, pp. 389-396
-
-
Poernbacher, I.1
Baumgartner, R.2
Marada, S.K.3
Edwards, K.4
Stocker, H.5
-
60
-
-
0027408247
-
Identification of a ten-amino acid proline-rich SH3 binding site
-
Ren R, Mayer BJ, Cicchetti P, Baltimore D. Identification of a ten-amino acid proline-rich SH3 binding site. Science. 1993;259:1157-61.
-
(1993)
Science
, vol.259
, pp. 1157-1161
-
-
Ren, R.1
Mayer, B.J.2
Cicchetti, P.3
Baltimore, D.4
-
61
-
-
79952298459
-
Yap1 acts downstream of alpha-catenin to control epidermal proliferation
-
Schlegelmilch K, Mohseni M, Kirak O, Pruszak J, Rodriguez JR, et al. Yap1 acts downstream of alpha-catenin to control epidermal proliferation. Cell. 2011;144:782-95.
-
(2011)
Cell
, vol.144
, pp. 782-795
-
-
Schlegelmilch, K.1
Mohseni, M.2
Kirak, O.3
Pruszak, J.4
Rodriguez, J.R.5
-
62
-
-
79957462240
-
Alpha-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1
-
Silvis MR, Kreger BT, Lien WH, Klezovitch O, Rudakova GM, et al. Alpha-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1. Sci Signal. 2011;4:ra33.
-
(2011)
Sci Signal
, vol.4
, pp. ra33
-
-
Silvis, M.R.1
Kreger, B.T.2
Lien, W.H.3
Klezovitch, O.4
Rudakova, G.M.5
-
63
-
-
84860484234
-
YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation
-
Skouloudaki K, Walz G. YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation. PLoS One. 2012;7:e35735.
-
(2012)
PLoS One
, vol.7
, pp. e35735
-
-
Skouloudaki, K.1
Walz, G.2
-
64
-
-
0028990361
-
Pez: A novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains
-
Smith AL, Mitchell PJ, Shipley J, Gusterson BA, Rogers MV, et al. Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains. Biochem Biophys Res Commun. 1995;209:959-65.
-
(1995)
Biochem Biophys Res Commun
, vol.209
, pp. 959-965
-
-
Smith, A.L.1
Mitchell, P.J.2
Shipley, J.3
Gusterson, B.A.4
Rogers, M.V.5
-
65
-
-
0035805487
-
Physical interaction with Yesassociated protein enhances p73 transcriptional activity
-
Strano S, Munarriz E, Rossi M, Castagnoli L, Shaul Y, et al. Physical interaction with Yesassociated protein enhances p73 transcriptional activity. J Biol Chem. 2001;276:15164-73.
-
(2001)
J Biol Chem
, vol.276
, pp. 15164-15173
-
-
Strano, S.1
Munarriz, E.2
Rossi, M.3
Castagnoli, L.4
Shaul, Y.5
-
66
-
-
0028283579
-
Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product
-
Sudol M. Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product. Oncogene. 1994;9:2145-52.
-
(1994)
Oncogene
, vol.9
, pp. 2145-2152
-
-
Sudol, M.1
-
67
-
-
0028997651
-
Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain
-
Sudol M, Bork P, Einbond A, Kastury K, Druck T, et al. Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain. J Biol Chem. 1995;270:14733-41.
-
(1995)
J Biol Chem
, vol.270
, pp. 14733-14741
-
-
Sudol, M.1
Bork, P.2
Einbond, A.3
Kastury, K.4
Druck, T.5
-
68
-
-
23044485188
-
WW domain
-
Cesareni G, Gimona M, Sudol M, Yaffe M, editors, Weinheim: Wiley VCH, Verlag Gmbh & Co
-
Sudol M. WW domain. In: Cesareni G, Gimona M, Sudol M, Yaffe M, editors. Modular protein domains. Weinheim: Wiley VCH, Verlag Gmbh & Co; 2004. p. 59-72.
-
(2004)
Modular Protein Domains
, pp. 59-72
-
-
Sudol, M.1
-
69
-
-
78049290801
-
Modularity in the Hippo signaling pathway
-
Sudol M, Harvey KF. Modularity in the Hippo signaling pathway. Trends Biochem Sci. 2010;35:627-33.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 627-633
-
-
Sudol, M.1
Harvey, K.F.2
-
70
-
-
84866634953
-
Structures of YAP protein domains reveal promising targets for development of new cancer drugs
-
Sudol M, Shields DC, Farooq A. Structures of YAP protein domains reveal promising targets for development of new cancer drugs. Semin Cell Dev Biol. 2012;23:827-33.
-
(2012)
Semin Cell Dev Biol
, vol.23
, pp. 827-833
-
-
Sudol, M.1
Shields, D.C.2
Farooq, A.3
-
71
-
-
79953149145
-
Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF
-
Tamm C, Bower N, Anneren C. Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF. J Cell Sci. 2011;124:1136-44.
-
(2011)
J Cell Sci
, vol.124
, pp. 1136-1144
-
-
Tamm, C.1
Bower, N.2
Anneren, C.3
-
72
-
-
33750510904
-
Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence
-
Takahashi A, Ohtani N, Yamakoshi K, Iida S, Tahara H, et al. Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence. Nat Cell Biol. 2006;8:1291-7.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1291-1297
-
-
Takahashi, A.1
Ohtani, N.2
Yamakoshi, K.3
Iida, S.4
Tahara, H.5
-
73
-
-
77952116604
-
Structural and functional analysis of the YAP-binding domain of human TEAD2
-
Tian W, Yu J, Tomchick DR, Pan D, Luo X. Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc Natl Acad Sci U S A. 2010;107:7293-8.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7293-7298
-
-
Tian, W.1
Yu, J.2
Tomchick, D.R.3
Pan, D.4
Luo, X.5
-
74
-
-
79551509783
-
Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner
-
Valis K, Prochazka L, Boura E, Chladova J, Obsil T, et al. Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner. Cancer Res. 2011;71:946-54.
-
(2011)
Cancer Res
, vol.71
, pp. 946-954
-
-
Valis, K.1
Prochazka, L.2
Boura, E.3
Chladova, J.4
Obsil, T.5
-
75
-
-
78649969033
-
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway
-
Varelas X, Samavarchi-Tehrani P, Narimatsu M, Weiss A, Cockburn K, et al. The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway. Dev Cell. 2010;19:831-44.
-
(2010)
Dev Cell
, vol.19
, pp. 831-844
-
-
Varelas, X.1
Samavarchi-Tehrani, P.2
Narimatsu, M.3
Weiss, A.4
Cockburn, K.5
-
76
-
-
84856514914
-
Coordinating developmental signaling: Novel roles for the Hippo pathway
-
Varelas X, Wrana JL. Coordinating developmental signaling: novel roles for the Hippo pathway. Trends Cell Biol. 2012;22:88-96.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 88-96
-
-
Varelas, X.1
Wrana, J.L.2
-
77
-
-
0035873391
-
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
-
Vassilev A, Kaneko KJ, Shu H, Zhao Y, DePamphilis ML. TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm. Genes Dev. 2001;15:1229-41.
-
(2001)
Genes Dev
, vol.15
, pp. 1229-1241
-
-
Vassilev, A.1
Kaneko, K.J.2
Shu, H.3
Zhao, Y.4
Depamphilis, M.L.5
-
78
-
-
0033828668
-
Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation
-
Wadham C, Gamble JR, Vadas MA, Khew-Goodall Y. Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation. J Cell Sci. 2000;113(Pt 17):3117-23.
-
(2000)
J Cell Sci
, vol.113
, pp. 3117-3123
-
-
Wadham, C.1
Gamble, J.R.2
Vadas, M.A.3
Khew-Goodall, Y.4
-
79
-
-
0038308412
-
The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin
-
Wadham C, Gamble JR, Vadas MA, Khew-Goodall Y. The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin. Mol Biol Cell. 2003;14:2520-9.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 2520-2529
-
-
Wadham, C.1
Gamble, J.R.2
Vadas, M.A.3
Khew-Goodall, Y.4
-
80
-
-
0032080043
-
Peptide binding consensus of the NHE-RFPDZ1 domain matches the C-terminal sequence of cysticfibrosis transmembrane conductance regulator (CFTR)
-
Wang S, Raab RW, Schatz PJ, Guggino WB, Li M. Peptide binding consensus of the NHE-RFPDZ1 domain matches the C-terminal sequence of cysticfibrosis transmembrane conductance regulator (CFTR). FEBS Lett. 1998;427:103-8.
-
(1998)
FEBS Lett
, vol.427
, pp. 103-108
-
-
Wang, S.1
Raab, R.W.2
Schatz, P.J.3
Guggino, W.B.4
Li, M.5
-
81
-
-
79953010044
-
Angiomotin-like proteins associate with and negatively regulate YAP1
-
Wang W, Huang J, Chen J. Angiomotin-like proteins associate with and negatively regulate YAP1. J Biol Chem. 2011;286:4364-70.
-
(2011)
J Biol Chem
, vol.286
, pp. 4364-4370
-
-
Wang, W.1
Huang, J.2
Chen, J.3
-
82
-
-
2442648882
-
Mutational analysis of the tyrosine phosphatome in colorectal cancers
-
Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science. 2004;304:1164-6.
-
(2004)
Science
, vol.304
, pp. 1164-1166
-
-
Wang, Z.1
Shen, D.2
Parsons, D.W.3
Bardelli, A.4
Sager, J.5
-
83
-
-
48849087797
-
PTP-Pez: A novel regulator of TGFbeta signaling
-
Wyatt L, Khew-Goodall Y. PTP-Pez: a novel regulator of TGFbeta signaling. Cell Cycle. 2008;7:2290-5.
-
(2008)
Cell Cycle
, vol.7
, pp. 2290-2295
-
-
Wyatt, L.1
Khew-Goodall, Y.2
-
84
-
-
77950231070
-
CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma
-
Xu Y, Stamenkovic I, Yu Q. CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma. Cancer Res. 2010;70:2455-64.
-
(2010)
Cancer Res
, vol.70
, pp. 2455-2464
-
-
Xu, Y.1
Stamenkovic, I.2
Yu, Q.3
-
85
-
-
0033522472
-
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
-
Yagi R, Chen LF, Shigesada K, Murakami Y, Ito Y. A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J. 1999;18:2551-62.
-
(1999)
EMBO J
, vol.18
, pp. 2551-2562
-
-
Yagi, R.1
Chen, L.F.2
Shigesada, K.3
Murakami, Y.4
Ito, Y.5
-
86
-
-
3242689902
-
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
-
Yang X, Yu K, Hao Y, Li DM, Stewart R, et al. LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1. Nat Cell Biol. 2004;6:609-17.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 609-617
-
-
Yang, X.1
Yu, K.2
Hao, Y.3
Li, D.M.4
Stewart, R.5
-
87
-
-
1842457741
-
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
-
Zaidi SK, Sullivan AJ, Medina R, Ito Y, van Wijnen AJ, et al. Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J. 2004; 23:790-9.
-
(2004)
EMBO J
, vol.23
, pp. 790-799
-
-
Zaidi, S.K.1
Sullivan, A.J.2
Medina, R.3
Ito, Y.4
Van Wijnen, A.J.5
-
88
-
-
42049120338
-
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
-
Zhang L, Ren F, Zhang Q, Chen Y, Wang B, et al. The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev Cell. 2008;14:377-87.
-
(2008)
Dev Cell
, vol.14
, pp. 377-387
-
-
Zhang, L.1
Ren, F.2
Zhang, Q.3
Chen, Y.4
Wang, B.5
-
89
-
-
78650895035
-
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
-
Zhao B, Li L, Lu Q, Wang LH, Liu CY, Lei Q, et al. Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev. 2011;25:51-63.
-
(2011)
Genes Dev
, vol.25
, pp. 51-63
-
-
Zhao, B.1
Li, L.2
Lu, Q.3
Wang, L.H.4
Liu, C.Y.5
Lei, Q.6
-
90
-
-
59149088576
-
Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein
-
Zhao B, Kim J, Ye X, Lai ZC, Guan KL. Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein. Cancer Res. 2009;69:1089-98.
-
(2009)
Cancer Res
, vol.69
, pp. 1089-1098
-
-
Zhao, B.1
Kim, J.2
Ye, X.3
Lai, Z.C.4
Guan, K.L.5
-
91
-
-
83755195660
-
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance
-
Zhou D, Zhang Y, Wu H, Barry E, Yin Y, et al. Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance. Proc Natl Acad Sci U S A. 2011;108:E1312-20.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. E1312-E1320
-
-
Zhou, D.1
Zhang, Y.2
Wu, H.3
Barry, E.4
Yin, Y.5
|