Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities

Chemistry and Biology

Volumn 8, Issue 3, 2001, Pages 231-241

  Kasanov, Jeremy ^a   Pirozzi, Gregorio ^b   Uveges, Albert J ^c   Kay, Brian K ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b Gene Logic Inc   (United States)

^c Wyeth Ayerst Research   (United States)

Author keywords

Combinatorial peptide; Phage display; Protein domain; Protein interaction module

Indexed keywords

AMINO ACID SUBSTITUTION; GENETIC CONSERVATION; LIGAND; MUTANT PROTEIN; PHAGE DISPLAY; PROTEIN DOMAIN; PROTEIN INTERACTION; SPECIFICITY; UBIQUITIN PROTEIN LIGASE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CONSERVED SEQUENCE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REPETITIVE SEQUENCES, AMINO ACID; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; TRYPTOPHAN;

EUKARYOTA;

EID: 0035071216     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(01)00005-9     Document Type: Article

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