Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β pathways

Structure

Volumn 20, Issue 10, 2012, Pages 1726-1736

  Aragón, Eric ^a   Goerner, Nina ^a,e   Xi, Qiaoran ^b   Gomes, Tiago ^a   Gao, Sheng ^b,f   Massagué, Joan ^b,c   MacIas, Maria J ^a,d  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^e BIOCRATES LIFE SCIENCES AG   (Austria)

^f MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR; GLYCOGEN SYNTHASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN SMURF1; PROTEIN SMURF2; REGULATOR PROTEIN; SMAD7 PROTEIN; TRANSCRIPTION FACTOR YAP1; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; CALORIMETRY; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; HUMANS; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, SECONDARY; SIGNAL TRANSDUCTION; SMAD7 PROTEIN; SURFACE PROPERTIES; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN-PROTEIN LIGASES;

EID: 84867372419     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.07.014     Document Type: Article

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