Platelet activating factor-induced apoptosis is inhibited by ectopic expression of the platelet activating factor G-protein coupled receptor

Journal of Neurochemistry

Volumn 82, Issue 6, 2002, Pages 1502-1511

  Brewer, Cynthia ^a   Bonin, Fanny ^a   Bullock, Paula ^a   Nault, Marie Christine ^a   Morin, Jennifer ^a   Imbeault, Sophie ^a   Shen, T Y ^b   Franks, D J ^a   Bennett, Steffany A L ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Apoptosis; CV3988; G protein coupled receptor; Ginkgolide B; Necrosis; Platelet activating factor

Indexed keywords

[2 METHOXY 3 (N OCTADECYLCARBAMOYLOXY)PROPYL] (2 THIAZOLIOETHYL) PHOSPHATE; G PROTEIN COUPLED RECEPTOR; GINKGOLIDE B; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CELL DEATH; CELL MEMBRANE; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA STRAND BREAKAGE; INFLAMMATION; MICELLE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEINS; HUMANS; IN SITU NICK-END LABELING; MICELLES; NECROSIS; PC12 CELLS; PHEOCHROMOCYTOMA; PLATELET ACTIVATING FACTOR; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; RATS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0036734851     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01094.x     Document Type: Article

References (47)

1. Ahlemeyer B., Möwes A. and Kriglstein J. (1999) Inhibition of serum deprivation- and staurosporine-induced neuronal apoptosis by Ginkgo biloba extract and some of its constituents. Eur. J. Pharmacol. 367, 423-430.
2. Barr R. M., Judge M., Mallet A. I., Kobza-Black A., Barlow R. and Greaves M. W. (1994) Platelet activating factor (PAF) and lyso-PAF in inflamed human skin. Agents Actions 41, Suppl. C2, C260-C261.
3. Bazan N. G. (1998) The neuromessenger platelet-activating factor in plasticity and neurodegeneration. Prog. Brain Res. 118, 281-291.
4. Bazan N. G., Rodriquez de Turco H. B. and Allan G. (1995) Mediators of injury in neurotrama: intracellular signal and gene expression. J. Neurotrama 12, 789-911.
5. Bennett S. A. L., Chen J. H. and Bimboim H. C. (1994) Recovery of a rare clone from a population of unstable retroviral vector-expressing mammalian cells using a new RNA extraction and slot-blot protocol. J. Virol. Meth. 50, 245-255.
6. Bennett S. A. L., Chen J., Pappas B. A., Roberts D. C. S. and Tenniswood M. (1998) Alterations in platelet activating factor receptor expression associated with neuronal apoptosis in an in vivo model of excitotoxicity. Cell Death Differ. 5, 867-875.
7. Birkle D. L., Kurian P., Braquet P. and Bazan N. G. (1998) Platelet activating factor antagonist BN52021 decreases accumulation of free polyunsaturated fatty acid in mouse brain during ischemia and electroconvulsive shock. J. Neurochem. 51, 1900-1905.
8. Bito H., Nakamura M., Honda Z., Izumi T., Iwatsubo T., Seyama Y., Ogura A., Kudo Y. and Shimizu T. (1992) Plate let-activating factor (PAF) receptor in rat brain: PAF mobilizes intracellular Ca2+ in hippocampal neurons. Neuron 9, 285-294.
9. Blank M. L., Lee T., Fitzgerald V. and Snyder F. (1981) A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid). J. Biol. Chem. 256, 175-178.
10. Carmody R. J. and Cotter T. G. (2001) Signaling apoptosis: a radical approach. Redox. Report 6, 77-90.
11. Chen C., Magee J. C., Marcheselli V., Hardy M. and Bazan N. G. (2001) Attenuated LTP in hippocampal dentate gyrus neurons of mice deficient in the PAF receptor. J. Neurophysiol. 85, 384-390.
12. Clark G. D., Happel L. T., Zorumski C. F. and Bazan N. G. (1992) Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor. Neuron 9, 1211-1216.
13. Clark G. D., Happel L. T., Zorumski C. F. and Bazan N. G. (1994) The role of platelet-activating-factor in the release of excitotoxic neurotransmitters. J. Lipid Med. 10, 95-97.
14. DeCoster M. A., Mukherjee P. K., Davis R. J. and Bazan N. G. (1998) Platelet-activating factor is a downstream messenger of kainate-induced activation of mitogen-activated protein kinases in primary hippocampal neurons. J. Neurosci. Res. 53, 297-303.
15. Garcia Rodriguez C., Cundell D. R., Tuomanen E. I., Kolakowski L. F. J., Gerard C. and Gerard N. P. (1995) The role of N-glycosylation for functional expression of the human platelet-activating factor receptor. Glycosylation is required for efficient membrane trafficking. J. Biol. Chem. 270, 25178-25184.
16. Gelbard H. A., Nottet H. S. L. M., Swindells S., Jett M., Dzenko K. A., Genis P., White R., Wang L., Choi Y.-B., Zhang D., Lipton S. A., Tourtellotte W. W., Epstein L. G. and Gendelman H. E. (1994) Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin. J. Virol. 68, 4628-4635.
17. Grassi S., Francescangeli E., Goracci G. and Pettorossi V. E. (2001) Platelet-activating factor and group I metabotropic glutamate receptors interact for full development and maintenance of longterm potentiation in the rat medial vestibular nuclei. Neuroscience 1999, 549-559.
18. Ishii S. and Shimizu T. (2000) Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice. Prog. Lipid Res. 39, 41-82.
19. Ishii I., Saito E., Izumi T., Ui M. and Shimizu T. (1998) Agonist-induced sequestration, recycling, and resensitization of platelet activating factor receptor. J. Biol. Chem. 273, 9878-9885.
20. Izquierdo I., Fin C., Schmitz P. K., Da Silva R. C., Jerusalinsky D., Quillfeldt J. A., Ferreira M. B. G., Medina J. H. and Bazan N. G. (1995) Memory enhancement by intrahippocampal, intraamygdala, or intraentorhinal infusion of platelet-activating factor measured in an inhibitory avoidance task. Proc. Natl Acad. Sci. USA 92, 5047-5051.
21. Kato K. (1999) Modulation of long-term potentiation in the CA1 area of rat hippocampus by platelet-activating factor. Adv. Exp. Med. 469, 221-227.
22. Kato K., Clark G. D., Bazan N. G. and Zorumski C. F. (1994) Platelet-activating factor as a potential retrograde messenger in CA1 hippocampal long-term potentiation. Nature 367, 175-179.
23. Kotelevets L., Noë V., Bruyneel E., Myssiakine E., Chastre E., Mareel M. and Gespach C. (1998) Inhibition by platelet-activating factor of src- and heptocyte growth factor-dependent invasiveness of intestinal and kidney epithelial cells. J. Biol. Chem. 273, 14138-14145.
24. Langley S. M., Chai P. J., Jaggers J. J. and Ungerleider R. M. (1999) Platelet activating factor receptor antagonism improves cerebral recovery after circulatory arrest. Ann. Thorac. Surg. 68, 1578-1584.
25. Marcheselli V. L., Rossowska M., Domingo M. T., Braquet P. and Bazan N. G. (1990) Distinct platelet-activating factor binding sites in synaptic endings and in intracellular membranes of rat cerebral cortex. J. Biol. Chem. 265, 9140-9145.
26. Mori M., Aihara M., Kume K., Hamanoue M., Kohsaka S. and Shimizu T. (1996) Predominant expression of platelet-activating factor receptor in rat brain microglia. J. Neurosci. 16, 3590-3600.
27. Mukherjee P. K., DeCoster M. A., Campbell F. Z., Davis R. J. and Bazan N. G. (1999) Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death. J. Biol. Chem. 274, 6493-6498.
28. Muller E., Dagenais P., Alami N. and Rola-Pleszczynski M. (1993) Identification and functional characterization of platelet activating factor receptors in human leukocyte populations using polyclonal anti-peptide antibodies. Proc. Natl Acad. Sci. USA 90, 5818-5821.
29. Mutoh H., Bito H., Minami M., Nakamura M., Honda Z., Izumi T., Nakata R., Kurachi Y., Terano A. and Shimizu T. (1993) Two different promoters direct expression of two distinct forms of mRNAs of human platelet-activating factor receptor. FEBS Lett. 322, 129-134.
30. Nunez D., Chignard M., Korth R., Le Couedic J. P., Norel X., Spinnewyn B., Braquet P. and Benveniste J. (1986) Specific inhibition of PAF-acether-induced platelet activation by BN 52021 and comparison with the PAF-acether inhibitors kadsurenone and CV 3988. Eur. J. Pharmacol. 123, 197-205.
31. Ohsima N., Ishii S., Izumi T. and Shimizu T. (2002) Receptor-dependent metabolism of platelet-activating factor in murine macrophages. J. Biol. Chem. 277, 9722-9727.
32. Pang J. H. S., Hung R. Y., Wu C. J., Fang Y. Y. and Chau L. Y. (1995) Functional characterization of the promoter region of the platelet-activating factor receptor gene. Identification of an initiator element essential for gene expression in myeloid cells. J. Biol. Chem. 270, 14123-14129.
33. Peplow P. V. (1999) Regulation of platelet-activating factor (PAF) activity in human diseases by phospholipase A2 inhibitors, PAF acetylhydrolases, PAF receptor antagonists and free radical scavengers. Prostaglandins Leukot. Essent. Fatty Acids 61, 65-82.
34. Perry S. W., Hamilton J. A., Tjoelker L. W., Dbaibo G., Dzenko K. A., Epstein L. G., Hannun Y., Whittaker J. S., Dewhurst S. and Gelbard H. A. (1998) Platelet activating factor receptor activation. An initiator step in HIV-1 neuropathogenesis. J. Biol. Chem. 273, 17660-17664.
35. Piechaczyk M., Blanchard J. M., Marty L., Dani C., Panabieres F., Sabouty S. E., Fort P. and Jeanteur P. (1984) Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues. Nucleic Acids Res. 12, 6951-6963.
36. Pulliam L., Zhou M., Stubblebine M. and Bitler C. M. (1998) Differential modulation of cell death proteins in human brain cells by tumour necrosis factor alpha and platelet activating factor. J. Neurosci. Res. 54, 530-538.
37. Schifitto G., Sacktor N., Marder K., McDermott M. P., McArthur J. C., Kieburtz K., Small S. and Epstein L. G. (1999) Randomized trial of the platelet-activating factor antagonist lexipafant in HIV-associated cognitive impairment. Neurological AIDS Research Consortium. Neurology 53, 391-396.
38. Serou M. J., DeCoster M. A. and Bazan N. G. (1999) Interleukin-1 beta activates expression of cyclooxygenase-2 and inducible nitric oxide synthase in primary hippocampal neuronal culture: platelet activating factor as a preferential mediator of cycooxygenase-2 expression. J. Neurosci. Res. 58, 593-598.
39. Southall M. D., Isenberg J. S., Nakshatri H., Yi Q., Pei Y., Spandau D. F. and Travers J. B. (2001) The platelet-activating factor receptor protects epidermal cells from TNF {alpha} and TRAIL-induced apoptosis through a NF-kB-dependent process. J. Biol. Chem. 276, 45548-45554.
40. Teather L. A., Packard M. G. and Bazan N. G. (1998) Effects of posttraining intrahippocampal injections of platelet-activating and PAF antagonists on memory. Neurobiol. Learn. Mem. 70, 349-363.
41. Terashita Z., Imura Y., Takatani M., Tsushima S. and Nishikawa K. (1987) CV-6209, a highly potent antagonist of platelet activating factor in vitro and in vivo. J. Pharmacol. Exp. Ther 242, 263-268.
42. Tiemann U., Tomek W., Schneider F., Wollenhaupt K., Kanitz W., Becker F., Pohland R. and Alm H. (2001) PAF-acetylhydrolase (PAF-AH) activity in bovine endometrium at different stages of estrous cycle and early pregnancy. Prostaglandins Other Lipid Med. 65, 125-141.
43. Tong N., Sanchez J. F., Maggirwar S. B., Ramierez S. H., Guo H., Dewhurst S. and Gelbard H. A. (2001) Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons. Eur. J. Neurosci. 13, 1913-1922.
44. Valone F. H. (1985) Inhibition of binding of the platelet-activating factor AGEPC to platelets by the AGEPC analog rac-3-(N-n-octadecylcarbamoyloxy)-2-methoxypropyl 2-thiazolioethyl phosphate (CV-3988). Biochem. Biophys. Res. Commun. 126, 502-508.
45. Westman J., Drieu K. and Sharma H. S. (2000) Antioxidant compounds EGB-761 and BN-520 21 attenuate heat shock protein (HSP 72 kD) response, edema and cell changes following hyperthermic brain injury. An experimental study using immunohistochemistry in the rat. Amino Acids 20, 2835-2847.
46. Wieraszko A., Li G., Kornecki E., Hogan M. V. and Ehrlich Y. H. (1993) Long-term potentiation in the hippocampus induced by platelet-activating factor. Neuron 10, 553-557.
47. Yoshikawa T., Naito Y. and Kondo M. (1999) Ginkgo biloba leaf extract: review of biological actions and clinical applications. Antioxid. Redox. Signal. 1, 469-480.