TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids

eLife

Volumn 3, Issue , 2014, Pages

  Muir, Alexander ^a   Ramachandran, Subramaniam ^a   Roelants, Françoise M ^a   Timmons, Garrett ^a   Thorner, Jeremy ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

biochemistry; cell biology; lipids; mutants; phosphorylation; plasma membrane; regulation; S. cerevisiae; substrates

Indexed keywords

CALCINEURIN; DIHYDROCERAMIDE DESATURASE; GLYCOGEN SYNTHASE KINASE 3; LAC1 PROTEIN, S CEREVISIAE; LAG1 PROTEIN, S CEREVISIAE; MCK1 PROTEIN, S CEREVISIAE; MEMBRANE PROTEIN; MULTIPROTEIN COMPLEX; OXIDOREDUCTASE; PHOSPHOSERINE; SACCHAROMYCES CEREVISIAE PROTEIN; SPHINGOLIPID; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

AUTOPHAGY; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL SURVIVAL; CYTOLOGY; DOWN REGULATION; ENZYME SPECIFICITY; ENZYMOLOGY; HEAT SHOCK RESPONSE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; UPREGULATION;

AUTOPHAGY; CALCINEURIN; CELL SURVIVAL; DOWN-REGULATION; GLYCOGEN SYNTHASE KINASE 3; HEAT-SHOCK RESPONSE; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MULTIPROTEIN COMPLEXES; OXIDOREDUCTASES; PHOSPHORYLATION; PHOSPHOSERINE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; SPHINGOLIPIDS; STRESS, PHYSIOLOGICAL; SUBSTRATE SPECIFICITY; TOR SERINE-THREONINE KINASES; UP-REGULATION;

EID: 85001819551     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.03779     Document Type: Article

References (0)