DAMP and DIC: The role of extracellular DNA and DNA-binding proteins in the pathogenesis of DIC

Blood Reviews

Volumn 30, Issue 4, 2016, Pages 257-261

  Liaw, Patricia C ^a   Ito, Takashi ^b   Iba, Toshiaki ^c   Thachil, Jecko ^d   Zeerleder, Sacha ^e  

^a MCMASTER UNIVERSITY   (Canada)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Damage associated molecular pattern; DAMP; DIC; Disseminated intravascular coagulation; Extracellular cell free DNA; Factor VII activating protease; FSAP; High mobility group box 1; Histones; NET; Neutrophil extracellular traps

Indexed keywords

BIOLOGICAL FACTOR; CELL FREE DNA; DAMAGE ASSOCIATED MOLECULAR PATTERN; DNA; DNA BINDING PROTEIN; EXTRACELLULAR DNA; FACTOR 7 ACTIVATING PROTEASE; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE; SERINE PROTEINASE; UNCLASSIFIED DRUG;

BLEEDING; BLOOD CLOT; BLOOD CLOTTING; CELL ACTIVATION; CELL DEATH; CIRCULATION; CYTOTOXICITY; DISSEMINATED INTRAVASCULAR CLOTTING; DNA STRUCTURE; EXTRACELLULAR TRAP; FIBRINOLYSIS; HEMATOPOIETIC CELL; HEMOSTASIS; HUMAN; INJURY; LEUKOCYTE ACTIVATION; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SECRETION; REVIEW; SEPSIS; THROMBOCYTE AGGREGATION; THROMBOSIS; GENETICS;

BLOOD COAGULATION; DISSEMINATED INTRAVASCULAR COAGULATION; DNA-BINDING PROTEINS; HUMANS; NEUTROPHIL ACTIVATION;

EID: 84953431903     PISSN: 0268960X     EISSN: 15321681     Source Type: Journal    
DOI: 10.1016/j.blre.2015.12.004     Document Type: Review

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