Cooperation of factor vii-activating protease and serum dnase i in the release of nucleosomes from necrotic cells

Arthritis and Rheumatology

Volumn 66, Issue 3, 2014, Pages 686-693

  Stephan, Femke ^a   Marsman, Gerben ^a   Bakker, Liza M ^a   Bulder, Ingrid ^a   Stavenuiter, Fabian ^a   Aarden, Lucien A ^a   Zeerleder, Sacha ^a  

^a CENTRAL LABORATORY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7 ACTIVATING PROTEASE; CELL DNA; DEOXYRIBONUCLEASE I; HISTONE H1; PROTEINASE; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ARTICLE; CELL DEATH; CHROMATIN; CONTROLLED STUDY; DNA CONTENT; DNA FRAGMENTATION; DNA STRAND BREAKAGE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MONONUCLEOSOME; NUCLEOSOME; PLASMINOGEN ACTIVATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUANTITATIVE ANALYSIS; SUPERNATANT; T LYMPHOCYTE;

CD4-POSITIVE T-LYMPHOCYTES; DEOXYRIBONUCLEASE I; HUMANS; JURKAT CELLS; NECROSIS; NUCLEOSOMES; SERINE ENDOPEPTIDASES;

EID: 84896289533     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38265     Document Type: Article

References (25)

1. Lauber K, Blumenthal SG, Waibel M, Wesselborg S. Clearance of apoptotic cells: getting rid of the corpses. Mol Cell 2004;14: 277-87.
2. Casciola-Rosen LA, Anhalt G, Rosen A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 1994; 179:1317-30.
3. Herrmann M, Voll RE, Zoller OM, Hagenhofer M, Ponner BB, Kalden Jr. Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus. Arthritis Rheum 1998;41:1241-50.
4. Walport MJ. Lupus, DNase and defective disposal of cellular debris. Nat Genet 2000;25:135-6.
5. Amoura Z, Chabre H, Bach JF, Koutouzov S. Antinucleosome antibodies and systemic lupus erythematosus. Adv Nephrol Necker Hosp 1997;26:303-16.
6. Amoura Z, Piette JC, Chabre H, Cacoub P, Papo T, Wechsler B, et al. Circulating plasma levels of nucleosomes in patients with systemic lupus erythematosus: correlation with serum antinucleosome antibody titers and absence of clear association with disease activity. Arthritis Rheum 1997;40:2217-25.
7. Chabre H, Amoura Z, Piette JC, Godeau P, Bach JF, Koutouzov S. Presence of nucleosome-restricted antibodies in patients with systemic lupus erythematosus. Arthritis Rheum 1995;38:1485-91.
8. Van Bruggen MC, Kramers C, Walgreen B, Elema JD, Kallenberg CG, Van Den Born J, et al. Nucleosomes and histones are present in glomerular deposits in human lupus nephritis. Nephrol Dial Transplant 1997;12:57-66.
9. Napirei M, Wulf S, Mannherz HG. Chromatin breakdown during necrosis by serum Dnase1 and the plasminogen system. Arthritis Rheum 2004;50:1873-83.
10. Chitrabamrung S, Rubin RL, Tan EM. Serum deoxyribonuclease I and clinical activity in systemic lupus erythematosus. Rheumatol Int 1981;1:55-60.
11. Sallai K, Nagy E, Derfalvy B, Muzes G, Gergely P. Antinucleosome antibodies and decreased deoxyribonuclease activity in sera of patients with systemic lupus erythematosus. Clin Diagn Lab Immunol 2005;12:56-9.
12. Zeerleder S, Zwart B, te Velthuis H, Manoe R, Bulder I, Rensink I, et al. A plasma nucleosome releasing factor (NRF) with serine protease activity is instrumental in removal of nucleosomes from secondary necrotic cells. FEBS Lett 2007;581:5382-8.
13. Zeerleder S, Zwart B, te Velthuis H, Stephan F, Manoe R, Rensink I, et al. Nucleosome-releasing factor: a new role for factor VII-activating protease (FSAP). FASEB J 2008;22:4077-84.
14. Etscheid M, Hunfeld A, Konig H, Seitz R, Dodt J. Activation of proPHBSP, the zymogen of a plasma hyaluronan binding serine protease, by an intermolecular autocatalytic mechanism. Biol Chem 2000;381:1223-31.
15. Stephan F, Hazelzet JA, Bulder I, Boermeester MA, van Till JO, van Der Poll T, et al. Activation of factor VII-activating protease in human inflammation: a sensor for cell death. Crit Care 2011;15: R110.
16. Stephan F, Dienava-Verdoold I, Bulder I, Wouters D, Mast AE, te Velthuis H, et al. Tissue factor pathway inhibitor is an inhibitor of factor VII-activating protease. J Thromb Haemost 2012;10: 1165-71.
17. Yamamichi S, Fujiwara Y, Kikuchi T, Nishitani M, Matsushita Y, Hasumi K. Extracellular histone induces plasma hyaluronanbinding protein (factor VII activating protease) activation in vivo. Biochem Biophys Res Commun 2011;409:483-8.
18. 2-antiplasmin complex with a novel monoclonal antibody based radioimmunoassay. Thromb Haemost 1992;67:111-6.
19. Van Nieuwenhuijze AE, van Lopik T, Smeenk RJ, Aarden LA. Time between onset of apoptosis and release of nucleosomes from apoptotic cells: putative implications for systemic lupus erythematosus. Ann Rheum Dis 2003;62:10-4.
20. Stavenuiter F, Dienava-Verdoold I, Boon-Spijker MG, Brinkman HJ, Meijer AB, Mertens K. Factor seven activating protease (FSAP): does it activate factor VII? J Thromb Haemost 2012;10: 859-66.
21. Kuijpers TW, Nguyen M, Hopman CT, Nieuwenhuys E, Dewald G, Lankester AC, et al. Complement factor 7 gene mutations in relation to meningococcal infection and clinical recurrence of meningococcal disease. Mol Immunol 2010;47:671-7.
22. Gauthier VJ, Tyler LN, Mannik M. Blood clearance kinetics and liver uptake of mononucleosomes in mice. J Immunol 1996;156: 1151-6.
23. Macanovic M, Lachmann PJ. Measurement of deoxyribonuclease I (DNase) in the serum and urine of systemic lupus erythematosus (SLE)-prone NZB/NZW mice by a new radial enzyme diffusion assay. Clin Exp Immunol 1997;108:220-6.
24. Wygrecka M, Morty RE, Markart P, Kanse SM, Andreasen PA, Wind T, et al. Plasminogen activator inhibitor-1 is an inhibitor of factor VII-activating protease in patients with acute respiratory distress syndrome. J Biol Chem 2007;282:21671-82.
25. Gaipl US, Beyer TD, Heyder P, Kuenkele S, Bottcher A, Voll RE, et al. Cooperation between C1q and DNase I in the clearance of necrotic cell-derived chromatin. Arthritis Rheum 2004;50:640-9.