Combination of antithrombin and recombinant thrombomodulin modulates neutrophil cell-death and decreases circulating DAMPs levels in endotoxemic rats

Thrombosis Research

Volumn 134, Issue 1, 2014, Pages 169-173

  Iba, Toshiaki ^a   Miki, Takahiro ^a   Hashiguchi, Naoyuki ^a   Tabe, Yoko ^a   Nagaoka, Isao ^a  

^a JUNTENDO UNIVERSITY   (Japan)

Author keywords

Antithrombin; Cell free DNA; Damage associated molecular patterns (DAMPs); Histone; Recombinant thrombomodulin; Sepsis

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTITHROMBIN; BILIRUBIN; BIOLOGICAL MARKER; CD DNA; CREATININE; FIBRINOGEN; GREEN FLUORESCENT PROTEIN; HISTONE H3; LIPOCORTIN 5; RECOMBINANT THROMBOMODULIN; UNCLASSIFIED DRUG; UREA; RECOMBINANT PROTEIN; THROMBOMODULIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CELL DEATH; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENDOTOXEMIA; FIBRINOGEN BLOOD LEVEL; LEUKOCYTE; LEUKOCYTE COUNT; MACROPHAGE; MONOCYTE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SEPSIS; UREA NITROGEN BLOOD LEVEL; ANIMAL; BLOOD; BLOOD CLOTTING; DRUG EFFECTS; LEUKOCYTE ACTIVATION; METABOLISM; WISTAR RAT;

ANIMALS; ANTITHROMBINS; BLOOD COAGULATION; CELL DEATH; ENDOTOXEMIA; NEUTROPHIL ACTIVATION; NEUTROPHILS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; SEPSIS; THROMBOMODULIN;

EID: 84902547699     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2014.04.015     Document Type: Article

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