-
2
-
-
43349096795
-
Inflammation, endothelium, and coagulation in sepsis
-
Schouten M, Wiersinga WJ, Levi M, et al: Inflammation, endothelium, and coagulation in sepsis. J Leukoc Biol 2008; 83:536-545
-
(2008)
J Leukoc Biol
, vol.83
, pp. 536-545
-
-
Schouten, M.1
Wiersinga, W.J.2
Levi, M.3
-
3
-
-
0031436402
-
Effects of inter-alpha-inhibitor in experimental endotoxic shock and disseminated intravascular coagulation
-
Jourdain M, Carrette O, Tournoys A, et al: Effects of inter-alpha-inhibitor in experimental endotoxic shock and disseminated intravascular coagulation. Am J Respir Crit Care Med 1997; 156:1825-1833
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 1825-1833
-
-
Jourdain, M.1
Carrette, O.2
Tournoys, A.3
-
4
-
-
84859802851
-
Tissue factor, blood coagulation, and beyond: An overview
-
Chu AJ: Tissue factor, blood coagulation, and beyond: An overview. Int J Inflam 2011; 2011:367284
-
(2011)
Int J Inflam
, vol.2011
, pp. 367284
-
-
Chu, A.J.1
-
5
-
-
0036910608
-
Antithrombin: A new look at the actions of a serine protease inhibitor
-
Roemisch J, Gray E, Hoffmann JN, et al: Antithrombin: A new look at the actions of a serine protease inhibitor. Blood Coagul Fibrinolysis 2002; 13:657-670
-
(2002)
Blood Coagul Fibrinolysis
, vol.13
, pp. 657-670
-
-
Roemisch, J.1
Gray, E.2
Hoffmann, J.N.3
-
6
-
-
77953504483
-
Regulation of the protein C anticoagulant and antiinflammatory pathways
-
Rezaie AR: Regulation of the protein C anticoagulant and antiinflammatory pathways. Curr Med Chem 2010; 17:2059-2069
-
(2010)
Curr Med Chem
, vol.17
, pp. 2059-2069
-
-
Rezaie, A.R.1
-
7
-
-
0038690407
-
OPTIMIST Trial Study Group: Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: A randomized controlled trial
-
Abraham E, Reinhart K, Opal S, et al; OPTIMIST Trial Study Group: Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: A randomized controlled trial. JAMA 2003; 290: 238-247
-
(2003)
JAMA
, vol.290
, pp. 238-247
-
-
Abraham, E.1
Reinhart, K.2
Opal, S.3
-
8
-
-
0035904368
-
Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: A randomized controlled trial
-
KyberSept Trial Study Group
-
Warren BL, Eid A, Singer P, et al; KyberSept Trial Study Group: Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: A randomized controlled trial. JAMA 2001; 286:1869-1878
-
(2001)
JAMA
, vol.286
, pp. 1869-1878
-
-
Warren, B.L.1
Eid, A.2
Singer, P.3
-
9
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group
-
Bernard GR, Vincent JL, Laterre PF, et al; Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group: Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001; 344:699-709
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
10
-
-
80052397217
-
Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense
-
Loof TG, Mörgelin M, Johansson L, et al: Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense. Blood 2011; 118:2589-2598
-
(2011)
Blood
, vol.118
, pp. 2589-2598
-
-
Loof, T.G.1
Mörgelin, M.2
Johansson, L.3
-
11
-
-
34548667697
-
Fibrinolysis and host response in bacterial infections
-
Bergmann S, Hammerschmidt S: Fibrinolysis and host response in bacterial infections. Thromb Haemost 2007; 98:512-520
-
(2007)
Thromb Haemost
, vol.98
, pp. 512-520
-
-
Bergmann, S.1
Hammerschmidt, S.2
-
12
-
-
61449163214
-
Corruption of innate immunity by bacterial proteases
-
Potempaa J, Pikeb RN: Corruption of innate immunity by bacterial proteases. J Innate Immun 2009; 1:70-87
-
(2009)
J Innate Immun
, vol.1
, pp. 70-87
-
-
Potempaa, J.1
Pikeb, R.N.2
-
13
-
-
34250736946
-
Fibrin and fibrinolysis in infection and host defense
-
Degen JL, Bugge TH, Goguen JD: Fibrin and fibrinolysis in infection and host defense. J Thromb Haemost 2007; 5 Suppl 1:24-31
-
(2007)
J Thromb Haemost
, vol.5
, Issue.SUPPL. 1
, pp. 24-31
-
-
Degen, J.L.1
Bugge, T.H.2
Goguen, J.D.3
-
14
-
-
60849087371
-
Reduced thrombin generation increases host susceptibility to group A streptococcal infection
-
Sun H, Wang X, Degen JL, et al: Reduced thrombin generation increases host susceptibility to group A streptococcal infection. Blood 2009; 113:1358-1364
-
(2009)
Blood
, vol.113
, pp. 1358-1364
-
-
Sun, H.1
Wang, X.2
Degen, J.L.3
-
15
-
-
80051919546
-
Protective roles for fibrin, tissue factor, plasminogen activator inhibitor-1, and thrombin activatable fibrinolysis inhibitor, but not factor XI, during defense against the gram-negative bacterium Yersinia enterocolitica
-
Luo D, Szaba FM, Kummer LW, et al: Protective roles for fibrin, tissue factor, plasminogen activator inhibitor-1, and thrombin activatable fibrinolysis inhibitor, but not factor XI, during defense against the gram-negative bacterium Yersinia enterocolitica. J Immunol 2011; 187:1866-1876
-
(2011)
J Immunol
, vol.187
, pp. 1866-1876
-
-
Luo, D.1
Szaba, F.M.2
Kummer, L.W.3
-
16
-
-
80052403217
-
From neutrophil extracellular traps release to thrombosis: An overshooting host-defense mechanism?
-
Borissoff JI, ten Cate H: From neutrophil extracellular traps release to thrombosis: An overshooting host-defense mechanism? J Thromb Haemost 2011; 9:1791-1794
-
(2011)
J Thromb Haemost
, vol.9
, pp. 1791-1794
-
-
Borissoff, J.I.1
Ten Cate, H.2
-
17
-
-
5444249967
-
Massive alveolar thrombin activation in Pseudomonas aeruginosa-induced acute lung injury
-
Kipnis E, Guery BP, Tournoys A, et al: Massive alveolar thrombin activation in Pseudomonas aeruginosa-induced acute lung injury. Shock 2004; 21:444-451
-
(2004)
Shock
, vol.21
, pp. 444-451
-
-
Kipnis, E.1
Guery, B.P.2
Tournoys, A.3
-
18
-
-
33645774438
-
Intravenous administration of activated protein C in Pseudomonas-induced lung injury: Impact on lung fluid balance and the inflammatory response
-
Robriquet L, Collet F, Tournoys A, et al: Intravenous administration of activated protein C in Pseudomonas-induced lung injury: Impact on lung fluid balance and the inflammatory response. Respir Res 2006; 7:41
-
(2006)
Respir Res
, vol.7
, pp. 41
-
-
Robriquet, L.1
Collet, F.2
Tournoys, A.3
-
19
-
-
34247388903
-
Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats
-
Choi G, Hofstra JJ, Roelofs JJ, et al: Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats. Crit Care Med 2007; 35:1362-1368
-
(2007)
Crit Care Med
, vol.35
, pp. 1362-1368
-
-
Choi, G.1
Hofstra, J.J.2
Roelofs, J.J.3
-
20
-
-
9844239909
-
Antithrombin acts as a negative acute phase protein as established with studies on HepG2 cells and in baboons
-
Niessen RW, Lamping RJ, Jansen PM, et al: Antithrombin acts as a negative acute phase protein as established with studies on HepG2 cells and in baboons. Thromb Haemost 1997; 78:1088-1092
-
(1997)
Thromb Haemost
, vol.78
, pp. 1088-1092
-
-
Niessen, R.W.1
Lamping, R.J.2
Jansen, P.M.3
-
21
-
-
58149250111
-
The response of antithrombin III activity after supplementation decreases in proportion to the severity of sepsis and liver dysfunction
-
Hayakawa M, Sawamura A, Yanagida Y, et al: The response of antithrombin III activity after supplementation decreases in proportion to the severity of sepsis and liver dysfunction. Shock 2008; 30:649-652
-
(2008)
Shock
, vol.30
, pp. 649-652
-
-
Hayakawa, M.1
Sawamura, A.2
Yanagida, Y.3
-
22
-
-
17944378441
-
Decreased plasma activity of antithrombin or protein C is not due to consumption coagulopathy in septic patients with disseminated intravascular coagulation
-
Asakura H, Ontachi Y, Mizutani T, et al: Decreased plasma activity of antithrombin or protein C is not due to consumption coagulopathy in septic patients with disseminated intravascular coagulation. Eur J Haematol 2001; 67:170-175
-
(2001)
Eur J Haematol
, vol.67
, pp. 170-175
-
-
Asakura, H.1
Ontachi, Y.2
Mizutani, T.3
-
23
-
-
0034985020
-
An enhanced fibrinolysis prevents the development of multiple organ failure in disseminated intravascular coagulation in spite of much activation of blood coagulation
-
Asakura H, Ontachi Y, Mizutani T, et al: An enhanced fibrinolysis prevents the development of multiple organ failure in disseminated intravascular coagulation in spite of much activation of blood coagulation. Crit Care Med 2001; 29:1164-1168
-
(2001)
Crit Care Med
, vol.29
, pp. 1164-1168
-
-
Asakura, H.1
Ontachi, Y.2
Mizutani, T.3
-
24
-
-
0029033356
-
Treatment of fulminant meningococcemia with recombinant tissue plasminogen activator
-
Zenz W, Muntean W, Zobel G, et al: Treatment of fulminant meningococcemia with recombinant tissue plasminogen activator. Thromb Haemost 1995; 74:802-803
-
(1995)
Thromb Haemost
, vol.74
, pp. 802-803
-
-
Zenz, W.1
Muntean, W.2
Zobel, G.3
-
25
-
-
0026534242
-
Septic shock, multiple organ failure, and disseminated intravascular coagulation Compared patterns of antithrombin III, protein C, and protein S deficiencies
-
Fourrier F, Chopin C, Goudemand J, et al: Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies. Chest 1992; 101:816-823
-
(1992)
Chest
, vol.101
, pp. 816-823
-
-
Fourrier, F.1
Chopin, C.2
Goudemand, J.3
-
26
-
-
13444283302
-
Dynamic evolution of coagulopathy in the first day of severe sepsis: Relationship with mortality and organ failure
-
Dhainaut JF, Shorr AF, Macias WL, et al: Dynamic evolution of coagulopathy in the first day of severe sepsis: Relationship with mortality and organ failure. Crit Care Med 2005; 33:341-348
-
(2005)
Crit Care Med
, vol.33
, pp. 341-348
-
-
Dhainaut, J.F.1
Shorr, A.F.2
MacIas, W.L.3
-
27
-
-
34247550884
-
Protein C concentrations in severe sepsis: An early directional change in plasma levels predicts outcome
-
Shorr AF, Bernard GR, Dhainaut JF, et al: Protein C concentrations in severe sepsis: An early directional change in plasma levels predicts outcome. Crit Care 2006; 10:R92
-
(2006)
Crit Care
, vol.10
-
-
Shorr, A.F.1
Bernard, G.R.2
Dhainaut, J.F.3
-
28
-
-
0035293659
-
Antithrombin reduces mesenteric venular leukocyte interactions and small intestine injury in endotoxemic rats
-
Nevière R, Tournoys A, Mordon S, et al: Antithrombin reduces mesenteric venular leukocyte interactions and small intestine injury in endotoxemic rats. Shock 2001; 15:220-225
-
(2001)
Shock
, vol.15
, pp. 220-225
-
-
Nevière, R.1
Tournoys, A.2
Mordon, S.3
-
29
-
-
0035833529
-
Dysfunction of endothelial protein C activation in severe meningococcal sepsis
-
Faust SN, Levin M, Harrison OB, et al: Dysfunction of endothelial protein C activation in severe meningococcal sepsis. N Engl J Med 2001; 345:408-416
-
(2001)
N Engl J Med
, vol.345
, pp. 408-416
-
-
Faust, S.N.1
Levin, M.2
Harrison, O.B.3
-
30
-
-
0038128677
-
Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: A randomized, double-blinded, placebo-controlled, dose-finding study
-
de Kleijn ED, de Groot R, Hack CE, et al: Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: A randomized, double-blinded, placebo-controlled, dose-finding study. Crit Care Med 2003; 31:1839-1847
-
(2003)
Crit Care Med
, vol.31
, pp. 1839-1847
-
-
De Kleijn, E.D.1
De Groot, R.2
Hack, C.E.3
-
31
-
-
79957948640
-
Et al; CAPTIVATE Trial Group: Recombinant tissue factor pathway inhibitor in severe community-acquired pneumonia: A randomized trial
-
Wunderink RG, Laterre PF, Francois B, et al; CAPTIVATE Trial Group: Recombinant tissue factor pathway inhibitor in severe community-acquired pneumonia: A randomized trial. Am J Respir Crit Care Med 2011; 183:1561-1568
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 1561-1568
-
-
Wunderink, R.G.1
Laterre, P.F.2
Francois, B.3
-
32
-
-
0037803423
-
Recombinant Human Activated Protein C Worldwide Evaluation in Sepsis (PROWESS) Study Group: Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: Data from the PROWESS trial
-
Dhainaut JF, Laterre PF, Janes JM, et al; Recombinant Human Activated Protein C Worldwide Evaluation in Sepsis (PROWESS) Study Group: Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: Data from the PROWESS trial. Intensive Care Med 2003; 29:894-903
-
(2003)
Intensive Care Med
, vol.29
, pp. 894-903
-
-
Dhainaut, J.F.1
Laterre, P.F.2
Janes, J.M.3
-
33
-
-
0037251585
-
PROWESS Investigators: Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis
-
Ely EW, Laterre PF, Angus DC, et al; PROWESS Investigators: Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis. Crit Care Med 2003; 31:12-19
-
(2003)
Crit Care Med
, vol.31
, pp. 12-19
-
-
Ely, E.W.1
Laterre, P.F.2
Angus, D.C.3
-
34
-
-
33748926949
-
A systematic review of antithrombin concentrate use in patients with disseminated intravascular coagulation of severe sepsis
-
Wiedermann CJ, Kaneider NC: A systematic review of antithrombin concentrate use in patients with disseminated intravascular coagulation of severe sepsis. Blood Coagul Fibrinolysis 2006; 17:521-526
-
(2006)
Blood Coagul Fibrinolysis
, vol.17
, pp. 521-526
-
-
Wiedermann, C.J.1
Kaneider, N.C.2
-
35
-
-
33644859949
-
Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation
-
KyberSept investigators
-
Kienast J, Juers M, Wiedermann CJ, et al; KyberSept investigators: Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation. J Thromb Haemost 2006; 4:90-97
-
(2006)
J Thromb Haemost
, vol.4
, pp. 90-97
-
-
Kienast, J.1
Juers, M.2
Wiedermann, C.J.3
-
36
-
-
33847687731
-
REsearching severe Sepsis and Organ dysfunction in children: A gLobal perspective (RESOLVE) study group: Drotrecogin alfa (activated) in children with severe sepsis: A multicentre phase III randomised controlled trial
-
Nadel S, Goldstein B, Williams MD, et al; REsearching severe Sepsis and Organ dysfunction in children: A gLobal perspective (RESOLVE) study group: Drotrecogin alfa (activated) in children with severe sepsis: A multicentre phase III randomised controlled trial. Lancet 2007; 369:836-843
-
(2007)
Lancet
, vol.369
, pp. 836-843
-
-
Nadel, S.1
Goldstein, B.2
Williams, M.D.3
-
37
-
-
0027171963
-
Double-blind, placebo-controlled trial of antithrombin III concentrates in septic shock with disseminated intravascular coagulation
-
Fourrier F, Chopin C, Huart JJ, et al: Double-blind, placebo-controlled trial of antithrombin III concentrates in septic shock with disseminated intravascular coagulation. Chest 1993; 104:882-888
-
(1993)
Chest
, vol.104
, pp. 882-888
-
-
Fourrier, F.1
Chopin, C.2
Huart, J.J.3
-
38
-
-
79955786719
-
Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: A historical control study
-
Yamakawa K, Fujimi S, Mohri T, et al: Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: A historical control study. Crit Care 2011; 15:R123
-
(2011)
Crit Care
, vol.15
-
-
Yamakawa, K.1
Fujimi, S.2
Mohri, T.3
|