메뉴 건너뛰기




Volumn 39, Issue , 2016, Pages 28-34

RNA nanomedicines: The next generation drugs?

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; DISEASES; GENE EXPRESSION; MOLECULES; NUCLEIC ACIDS; TUMORS;

EID: 84953310429     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2015.12.011     Document Type: Review
Times cited : (32)

References (61)
  • 1
    • 84930388499 scopus 로고    scopus 로고
    • Harnessing RNAi nanomedicine for precision therapy
    • Peer D. Harnessing RNAi nanomedicine for precision therapy. Mol Cell Therap 2014, 2:5.
    • (2014) Mol Cell Therap , vol.2 , pp. 5
    • Peer, D.1
  • 2
    • 84908564426 scopus 로고    scopus 로고
    • Current issues of RNAi therapeutics delivery and development
    • Haussecker D. Current issues of RNAi therapeutics delivery and development. J Control Release 2014, 195:49-54.
    • (2014) J Control Release , vol.195 , pp. 49-54
    • Haussecker, D.1
  • 4
    • 84867642276 scopus 로고    scopus 로고
    • RNAi-based nanomedicines for targeted personalized therapy
    • Daka A., Peer D. RNAi-based nanomedicines for targeted personalized therapy. Adv Drug Deliv Rev 2012, 64:1508-1521.
    • (2012) Adv Drug Deliv Rev , vol.64 , pp. 1508-1521
    • Daka, A.1    Peer, D.2
  • 10
    • 84938747156 scopus 로고    scopus 로고
    • Targeted therapy for breast cancer stem cells by liposomal delivery of siRNA against fibronectin EDB
    • Sun Y., Kim H.S., Saw P.E., Jon S., Moon W.K. Targeted therapy for breast cancer stem cells by liposomal delivery of siRNA against fibronectin EDB. Adv Healthc Mater 2015, 4:1675-1680.
    • (2015) Adv Healthc Mater , vol.4 , pp. 1675-1680
    • Sun, Y.1    Kim, H.S.2    Saw, P.E.3    Jon, S.4    Moon, W.K.5
  • 11
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 1986, 46:6387-6392.
    • (1986) Cancer Res , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 12
    • 84897003921 scopus 로고    scopus 로고
    • Modulation of drug resistance in ovarian adenocarcinoma using chemotherapy entrapped in hyaluronan-grafted nanoparticle clusters
    • Cohen K., Emmanuel R., Kisin-Finfer E., Shabat D., Peer D. Modulation of drug resistance in ovarian adenocarcinoma using chemotherapy entrapped in hyaluronan-grafted nanoparticle clusters. ACS Nano 2014, 8:2183-2195.
    • (2014) ACS Nano , vol.8 , pp. 2183-2195
    • Cohen, K.1    Emmanuel, R.2    Kisin-Finfer, E.3    Shabat, D.4    Peer, D.5
  • 13
    • 84924411834 scopus 로고    scopus 로고
    • Aptamers: active targeting ligands for cancer diagnosis and therapy
    • Wu X., Chen J., Wu M., Zhao J.X. Aptamers: active targeting ligands for cancer diagnosis and therapy. Theranostics 2015, 5:322-344.
    • (2015) Theranostics , vol.5 , pp. 322-344
    • Wu, X.1    Chen, J.2    Wu, M.3    Zhao, J.X.4
  • 14
  • 15
    • 84938423574 scopus 로고    scopus 로고
    • Nanomedicine as an emerging platform for metastatic lung cancer therapy
    • Landesman-Milo D., Ramishetti S., Peer D. Nanomedicine as an emerging platform for metastatic lung cancer therapy. Cancer Metastasis Rev 2015, 34:291-301.
    • (2015) Cancer Metastasis Rev , vol.34 , pp. 291-301
    • Landesman-Milo, D.1    Ramishetti, S.2    Peer, D.3
  • 16
    • 84923459414 scopus 로고    scopus 로고
    • Localized RNAi therapeutics of chemoresistant grade IV glioma using hyaluronan-grafted lipid-based nanoparticles
    • Cohen Z.R., Ramishetti S., Peshes-Yaloz N., Goldsmith M., Wohl A., Zibly Z., Peer D. Localized RNAi therapeutics of chemoresistant grade IV glioma using hyaluronan-grafted lipid-based nanoparticles. ACS Nano 2015, 9:1581-1591.
    • (2015) ACS Nano , vol.9 , pp. 1581-1591
    • Cohen, Z.R.1    Ramishetti, S.2    Peshes-Yaloz, N.3    Goldsmith, M.4    Wohl, A.5    Zibly, Z.6    Peer, D.7
  • 18
    • 77954385672 scopus 로고    scopus 로고
    • The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation
    • Kedmi R., Ben-Arie N., Peer D. The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation. Biomaterials 2010, 31:6867-6875.
    • (2010) Biomaterials , vol.31 , pp. 6867-6875
    • Kedmi, R.1    Ben-Arie, N.2    Peer, D.3
  • 19
    • 84893531193 scopus 로고    scopus 로고
    • Toxicity profiling of several common RNAi-based nanomedicines: a comparative study
    • Landesman-Milo D., Peer D. Toxicity profiling of several common RNAi-based nanomedicines: a comparative study. Drug Deliv Transl Res 2014, 4:96-103.
    • (2014) Drug Deliv Transl Res , vol.4 , pp. 96-103
    • Landesman-Milo, D.1    Peer, D.2
  • 24
    • 67149115119 scopus 로고    scopus 로고
    • Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
    • Khan A.A., Betel D., Miller M.L., Sander C., Leslie C.S., Marks D.S. Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. Nat Biotechnol 2009, 27:549-555.
    • (2009) Nat Biotechnol , vol.27 , pp. 549-555
    • Khan, A.A.1    Betel, D.2    Miller, M.L.3    Sander, C.4    Leslie, C.S.5    Marks, D.S.6
  • 25
    • 84891340265 scopus 로고    scopus 로고
    • Stable RNA interference rules for silencing
    • Fellmann C., Lowe S.W. Stable RNA interference rules for silencing. Nat Cell Biol 2014, 16:10-18.
    • (2014) Nat Cell Biol , vol.16 , pp. 10-18
    • Fellmann, C.1    Lowe, S.W.2
  • 27
    • 84896697586 scopus 로고    scopus 로고
    • Image-based analysis of the size- and time-dependent penetration of polymeric micelles in multicellular tumor spheroids and tumor xenografts
    • Mikhail A.S., Eetezadi S., Ekdawi S.N., Stewart J., Allen C. Image-based analysis of the size- and time-dependent penetration of polymeric micelles in multicellular tumor spheroids and tumor xenografts. Int J Pharm 2014, 464:168-177.
    • (2014) Int J Pharm , vol.464 , pp. 168-177
    • Mikhail, A.S.1    Eetezadi, S.2    Ekdawi, S.N.3    Stewart, J.4    Allen, C.5
  • 28
  • 30
    • 78049452610 scopus 로고    scopus 로고
    • Delivering nanomedicine to solid tumors
    • Jain R.K., Stylianopoulos T. Delivering nanomedicine to solid tumors. Nat Rev Clin Oncol 2010, 7:653-664.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 653-664
    • Jain, R.K.1    Stylianopoulos, T.2
  • 31
    • 81255143243 scopus 로고    scopus 로고
    • Improving delivery and efficacy of nanomedicines in solid tumors: role of tumor priming
    • Wang J., Lu Z., Gao Y., Wientjes M.G., Au J.L. Improving delivery and efficacy of nanomedicines in solid tumors: role of tumor priming. Nanomedicine (Lond) 2011, 6:1605-1620.
    • (2011) Nanomedicine (Lond) , vol.6 , pp. 1605-1620
    • Wang, J.1    Lu, Z.2    Gao, Y.3    Wientjes, M.G.4    Au, J.L.5
  • 32
    • 84872838282 scopus 로고    scopus 로고
    • Markedly enhanced permeability and retention effects induced by photo-immunotherapy of tumors
    • Sano K., Nakajima T., Choyke P.L., Kobayashi H. Markedly enhanced permeability and retention effects induced by photo-immunotherapy of tumors. ACS Nano 2013, 7:717-724.
    • (2013) ACS Nano , vol.7 , pp. 717-724
    • Sano, K.1    Nakajima, T.2    Choyke, P.L.3    Kobayashi, H.4
  • 33
    • 34250765337 scopus 로고    scopus 로고
    • Tumor priming enhances delivery and efficacy of nanomedicines
    • Lu D., Wientjes M.G., Lu Z., Au J.L. Tumor priming enhances delivery and efficacy of nanomedicines. J Pharmacol Exp Therap 2007, 322:80-88.
    • (2007) J Pharmacol Exp Therap , vol.322 , pp. 80-88
    • Lu, D.1    Wientjes, M.G.2    Lu, Z.3    Au, J.L.4
  • 34
    • 84921711123 scopus 로고    scopus 로고
    • Improving drug delivery to solid tumors: priming the tumor microenvironment
    • Khawar I.A., Kim J.H., Kuh H.J. Improving drug delivery to solid tumors: priming the tumor microenvironment. J Control Release 2015, 201:78-89.
    • (2015) J Control Release , vol.201 , pp. 78-89
    • Khawar, I.A.1    Kim, J.H.2    Kuh, H.J.3
  • 35
    • 84881539307 scopus 로고    scopus 로고
    • HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression
    • Philip B., Ito K., Moreno-Sanchez R., Ralph S.J. HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression. Carcinogenesis 2013, 34:1699-1707.
    • (2013) Carcinogenesis , vol.34 , pp. 1699-1707
    • Philip, B.1    Ito, K.2    Moreno-Sanchez, R.3    Ralph, S.J.4
  • 37
    • 84893769522 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-beta signalling
    • Yu Y., Xiao C.H., Tan L.D., Wang Q.S., Li X.Q., Feng Y.M. Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-beta signalling. Br J Cancer 2014, 110:724-732.
    • (2014) Br J Cancer , vol.110 , pp. 724-732
    • Yu, Y.1    Xiao, C.H.2    Tan, L.D.3    Wang, Q.S.4    Li, X.Q.5    Feng, Y.M.6
  • 39
    • 84924249260 scopus 로고    scopus 로고
    • The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?
    • Plaks V., Kong N., Werb Z. The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?. Cell Stem Cell 2015, 16:225-238.
    • (2015) Cell Stem Cell , vol.16 , pp. 225-238
    • Plaks, V.1    Kong, N.2    Werb, Z.3
  • 40
    • 84888639681 scopus 로고    scopus 로고
    • The roles of TGFbeta in the tumour microenvironment
    • Pickup M., Novitskiy S., Moses H.L. The roles of TGFbeta in the tumour microenvironment. Nat Rev Cancer 2013, 13:788-799.
    • (2013) Nat Rev Cancer , vol.13 , pp. 788-799
    • Pickup, M.1    Novitskiy, S.2    Moses, H.L.3
  • 41
    • 84937970942 scopus 로고    scopus 로고
    • Tumorigenesis: it takes a village
    • Tabassum D.P., Polyak K. Tumorigenesis: it takes a village. Nat Rev Cancer 2015, 15:473-483.
    • (2015) Nat Rev Cancer , vol.15 , pp. 473-483
    • Tabassum, D.P.1    Polyak, K.2
  • 42
    • 84955387882 scopus 로고    scopus 로고
    • Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy
    • Zins K., Sioud M., Aharinejad S., Lucas T., Abraham D. Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy. Methods Mol Biol 2015, 1218:143-161.
    • (2015) Methods Mol Biol , vol.1218 , pp. 143-161
    • Zins, K.1    Sioud, M.2    Aharinejad, S.3    Lucas, T.4    Abraham, D.5
  • 43
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • Quail D.F., Joyce J.A. Microenvironmental regulation of tumor progression and metastasis. Nat Med 2013, 19:1423-1437.
    • (2013) Nat Med , vol.19 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 44
    • 84880626610 scopus 로고    scopus 로고
    • Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model
    • Cai F., Li Z., Wang C., Xian S., Xu G., Peng F., Wei Y., Lu Y. Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model. BMB Rep 2013, 46:252-257.
    • (2013) BMB Rep , vol.46 , pp. 252-257
    • Cai, F.1    Li, Z.2    Wang, C.3    Xian, S.4    Xu, G.5    Peng, F.6    Wei, Y.7    Lu, Y.8
  • 45
    • 84948568477 scopus 로고    scopus 로고
    • Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumor-associated macrophages and cancer cells
    • Conde J., Bao C.C., Tan Y.Q., Cui D.X., Edelman E.R., Azevedo H.S., Byrne H.J., Artzi N., Tian F.R. Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumor-associated macrophages and cancer cells. Adv Funct Mater 2015, 25:4183-4194.
    • (2015) Adv Funct Mater , vol.25 , pp. 4183-4194
    • Conde, J.1    Bao, C.C.2    Tan, Y.Q.3    Cui, D.X.4    Edelman, E.R.5    Azevedo, H.S.6    Byrne, H.J.7    Artzi, N.8    Tian, F.R.9
  • 46
    • 84899457547 scopus 로고    scopus 로고
    • Nanoparticle-delivered transforming growth factor-beta siRNA enhances vaccination against advanced melanoma by modifying tumor microenvironment
    • Xu Z., Wang Y., Zhang L., Huang L. Nanoparticle-delivered transforming growth factor-beta siRNA enhances vaccination against advanced melanoma by modifying tumor microenvironment. ACS Nano 2014, 8:3636-3645.
    • (2014) ACS Nano , vol.8 , pp. 3636-3645
    • Xu, Z.1    Wang, Y.2    Zhang, L.3    Huang, L.4
  • 48
    • 84948718039 scopus 로고    scopus 로고
    • Delivery of siRNA using CXCR4-targeted nanoparticles modulates tumor microenvironment and achieves a potent anti-tumor response in liver cancer
    • Liu J.Y., Chiang T., Liu C.H., Chern G.G., Lin T.T., Gao D.Y., Chen Y. Delivery of siRNA using CXCR4-targeted nanoparticles modulates tumor microenvironment and achieves a potent anti-tumor response in liver cancer. Mol Therap 2015.
    • (2015) Mol Therap
    • Liu, J.Y.1    Chiang, T.2    Liu, C.H.3    Chern, G.G.4    Lin, T.T.5    Gao, D.Y.6    Chen, Y.7
  • 49
    • 84938523103 scopus 로고    scopus 로고
    • Silencing beta3 integrin by targeted ECO/siRNA nanoparticles inhibits EMT and metastasis of triple-negative breast cancer
    • Parvani J.G., Gujrati M.D., Mack M.A., Schiemann W.P., Lu Z.R. Silencing beta3 integrin by targeted ECO/siRNA nanoparticles inhibits EMT and metastasis of triple-negative breast cancer. Cancer Res 2015, 75:2316-2325.
    • (2015) Cancer Res , vol.75 , pp. 2316-2325
    • Parvani, J.G.1    Gujrati, M.D.2    Mack, M.A.3    Schiemann, W.P.4    Lu, Z.R.5
  • 51
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • Kerbel R.S. Tumor angiogenesis. N Engl J Med 2008, 358:2039-2049.
    • (2008) N Engl J Med , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 52
    • 84912079521 scopus 로고    scopus 로고
    • Nanovaccine loaded with poly I:C and STAT3 siRNA robustly elicits anti-tumor immune responses through modulating tumor-associated dendritic cells in vivo
    • Luo Z., Wang C., Yi H., Li P., Pan H., Liu L., Cai L., Ma Y. Nanovaccine loaded with poly I:C and STAT3 siRNA robustly elicits anti-tumor immune responses through modulating tumor-associated dendritic cells in vivo. Biomaterials 2015, 38:50-60.
    • (2015) Biomaterials , vol.38 , pp. 50-60
    • Luo, Z.1    Wang, C.2    Yi, H.3    Li, P.4    Pan, H.5    Liu, L.6    Cai, L.7    Ma, Y.8
  • 54
    • 84867120348 scopus 로고    scopus 로고
    • Rab27a supports exosome-dependent and -independent mechanisms that modify the tumor microenvironment and can promote tumor progression
    • Bobrie A., Krumeich S., Reyal F., Recchi C., Moita L.F., Seabra M.C., Ostrowski M., Thery C. Rab27a supports exosome-dependent and -independent mechanisms that modify the tumor microenvironment and can promote tumor progression. Cancer Res 2012, 72:4920-4930.
    • (2012) Cancer Res , vol.72 , pp. 4920-4930
    • Bobrie, A.1    Krumeich, S.2    Reyal, F.3    Recchi, C.4    Moita, L.F.5    Seabra, M.C.6    Ostrowski, M.7    Thery, C.8
  • 55
    • 38849166053 scopus 로고    scopus 로고
    • Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target
    • Peer D., Park E.J., Morishita Y., Carman C.V., Shimaoka M. Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target. Science 2008, 319:627-630.
    • (2008) Science , vol.319 , pp. 627-630
    • Peer, D.1    Park, E.J.2    Morishita, Y.3    Carman, C.V.4    Shimaoka, M.5
  • 56
    • 34247255870 scopus 로고    scopus 로고
    • Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1
    • Peer D., Zhu P., Carman C.V., Lieberman J., Shimaoka M. Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1. Proc Natl Acad Sci U S A 2007, 104:4095-4100.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 4095-4100
    • Peer, D.1    Zhu, P.2    Carman, C.V.3    Lieberman, J.4    Shimaoka, M.5
  • 57
    • 84934307590 scopus 로고    scopus 로고
    • Knocking down disease: a progress report on siRNA therapeutics
    • Wittrup A., Lieberman J. Knocking down disease: a progress report on siRNA therapeutics. Nat Rev Genet 2015, 16:543-552.
    • (2015) Nat Rev Genet , vol.16 , pp. 543-552
    • Wittrup, A.1    Lieberman, J.2
  • 58
    • 84924625044 scopus 로고    scopus 로고
    • Are RNAi and miRNA therapeutics truly dead?
    • Conde J., Artzi N. Are RNAi and miRNA therapeutics truly dead?. Trends Biotechnol 2015, 33:141-144.
    • (2015) Trends Biotechnol , vol.33 , pp. 141-144
    • Conde, J.1    Artzi, N.2
  • 61
    • 84891831985 scopus 로고    scopus 로고
    • In vitro and in vivo efficacy of SYL040012, a novel siRNA compound for treatment of glaucoma
    • Martinez T., Gonzalez M.V., Roehl I., Wright N., Paneda C., Jimenez A.I. In vitro and in vivo efficacy of SYL040012, a novel siRNA compound for treatment of glaucoma. Mol Therap 2014, 22:81-91.
    • (2014) Mol Therap , vol.22 , pp. 81-91
    • Martinez, T.1    Gonzalez, M.V.2    Roehl, I.3    Wright, N.4    Paneda, C.5    Jimenez, A.I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.