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Volumn 46, Issue 5, 2013, Pages 252-257

Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model

Author keywords

Angiogenesis; Breast cancer; Fibroblast activation protein; RNA interference; Tumor microenvironment

Indexed keywords

GELATINASE; MEMBRANE PROTEIN; SEPRASE; SERINE PROTEINASE; SMALL INTERFERING RNA;

EID: 84880626610     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2013.46.5.172     Document Type: Article
Times cited : (21)

References (30)
  • 2
    • 80051509468 scopus 로고    scopus 로고
    • Emerging trends in the treatment of triple-negative breast cancer in Canada: a survey
    • Verma, S., Provencher, L. and Dent, R. (2011) Emerging trends in the treatment of triple-negative breast cancer in Canada: a survey. Curr. Oncol. 18, 180-190.
    • (2011) Curr. Oncol. , vol.18 , pp. 180-190
    • Verma, S.1    Provencher, L.2    Dent, R.3
  • 3
    • 0005429990 scopus 로고
    • Cell-surface glycoproteins of human sarcomas: differential expression in normal and malignant tissues and cultured cells
    • Rettig, W. J., Garin-Chesa, P., Beresford, H. R., Oettgen, H. F., Melamed, M. R. and Old, L. J. (1988) Cell-surface glycoproteins of human sarcomas: differential expression in normal and malignant tissues and cultured cells. Proc. Natl. Acad. Sci. U.S.A. 85, 3110-3114.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 3110-3114
    • Rettig, W.J.1    Garin-Chesa, P.2    Beresford, H.R.3    Oettgen, H.F.4    Melamed, M.R.5    Old, L.J.6
  • 4
    • 0036113238 scopus 로고    scopus 로고
    • Tumor-associated fibroblasts (part I): Active stromal participants in tumor development and progression?
    • Kunz-Schughart, L. A. and Knuechel, R. (2002) Tumor-associated fibroblasts (part I): Active stromal participants in tumor development and progression? Histol. Histopathol. 17, 599-621.
    • (2002) Histol. Histopathol. , vol.17 , pp. 599-621
    • Kunz-Schughart, L.A.1    Knuechel, R.2
  • 6
    • 33846018363 scopus 로고    scopus 로고
    • Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III and IV
    • Christiansen, V. J., Jackson, K. W., Lee, K. N. and McKee, P. A. (2007) Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III and IV. Arch. Biochem. Biophys. 457, 177-186.
    • (2007) Arch. Biochem. Biophys. , vol.457 , pp. 177-186
    • Christiansen, V.J.1    Jackson, K.W.2    Lee, K.N.3    McKee, P.A.4
  • 7
    • 15944389319 scopus 로고    scopus 로고
    • Seprase promotes rapid tumor growth and increased microvessel density in a mouse model of human breast cancer
    • Huang, Y., Wang, S. and Kelly, T. (2004) Seprase promotes rapid tumor growth and increased microvessel density in a mouse model of human breast cancer. Cancer Res. 64, 2712-2716.
    • (2004) Cancer Res. , vol.64 , pp. 2712-2716
    • Huang, Y.1    Wang, S.2    Kelly, T.3
  • 8
    • 0037102412 scopus 로고    scopus 로고
    • Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model
    • Cheng, J. D., Dunbrack, R. L. Jr., Valianou, M., Rogatko, A., Alpaugh, R. K. and Weiner, L. M. (2002) Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model. Cancer Res. 62, 4767-4772.
    • (2002) Cancer Res. , vol.62 , pp. 4767-4772
    • Cheng, J.D.1    Dunbrack Jr., R.L.2    Valianou, M.3    Rogatko, A.4    Alpaugh, R.K.5    Weiner, L.M.6
  • 9
    • 77952568396 scopus 로고    scopus 로고
    • Hallmarks of cancer: interactions with the tumor stroma
    • Pietras, K. and Ostman, A. (2010) Hallmarks of cancer: interactions with the tumor stroma. Exp. Cell Res. 316, 1324-1331.
    • (2010) Exp. Cell Res. , vol.316 , pp. 1324-1331
    • Pietras, K.1    Ostman, A.2
  • 10
    • 77956667224 scopus 로고    scopus 로고
    • Selective gene silencing by viral delivery of short hairpin RNA
    • Sliva, K. and Schnierle, B. S. (2010) Selective gene silencing by viral delivery of short hairpin RNA. Virol. J. 7, 248.
    • (2010) Virol. J. , vol.7 , pp. 248
    • Sliva, K.1    Schnierle, B.S.2
  • 11
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon, G. J. and Rossi, J. J. (2004) Unlocking the potential of the human genome with RNA interference. Nature 431, 371-378.
    • (2004) Nature , vol.431 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 15
    • 58849131828 scopus 로고    scopus 로고
    • Cancer and the tumor microenvironment: a review of an essential relationship.
    • Mbeunkui, F. and Johann, D. J. Jr. (2009) Cancer and the tumor microenvironment: a review of an essential relationship. Cancer Chemother. Pharmacol. 63, 571-582.
    • (2009) Cancer Chemother. Pharmacol. , vol.63 , pp. 571-582
    • Mbeunkui, F.1    Johann, D.J.Jr.2
  • 16
    • 0022891340 scopus 로고
    • Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak, H. F. (1986) Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 315, 1650-1659.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 17
    • 33745837774 scopus 로고    scopus 로고
    • Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
    • Loeffler, M., Kruger, J. A., Niethammer, A. G. and Reisfeld, R. A. (2006) Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J. Clin. Invest. 116, 1955-1962.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1955-1962
    • Loeffler, M.1    Kruger, J.A.2    Niethammer, A.G.3    Reisfeld, R.A.4
  • 19
    • 3442900472 scopus 로고    scopus 로고
    • PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism
    • Adams, S., Miller, G. T., Jesson, M. I., Watanabe, T., Jones, B. and Wallner, B. P. (2004) PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism. Cancer Res. 64, 5471-5480.
    • (2004) Cancer Res. , vol.64 , pp. 5471-5480
    • Adams, S.1    Miller, G.T.2    Jesson, M.I.3    Watanabe, T.4    Jones, B.5    Wallner, B.P.6
  • 20
    • 72849125358 scopus 로고    scopus 로고
    • Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice
    • Santos, A. M., Jung, J., Aziz, N., Kissil, J. L. and Pure, E. (2009) Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. J. Clin. Invest. 119, 3613-3625.
    • (2009) J. Clin. Invest. , vol.119 , pp. 3613-3625
    • Santos, A.M.1    Jung, J.2    Aziz, N.3    Kissil, J.L.4    Pure, E.5
  • 21
    • 79960898998 scopus 로고    scopus 로고
    • Fibroblast activation protein-alpha promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions
    • Huang, Y., Simms, A. E., Mazur, A., Wang, S., Leon, N. R., Jones, B., Aziz, N. and Kelly, T. (2011) Fibroblast activation protein-alpha promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions. Clin. Exp. Metastasis 28, 567-579.
    • (2011) Clin. Exp. Metastasis , vol.28 , pp. 567-579
    • Huang, Y.1    Simms, A.E.2    Mazur, A.3    Wang, S.4    Leon, N.R.5    Jones, B.6    Aziz, N.7    Kelly, T.8
  • 22
    • 0035320245 scopus 로고    scopus 로고
    • It takes a tissue to make a tumor: epigenetics, cancer and the microenvironment
    • Barcellos-Hoff, M. H. (2001) It takes a tissue to make a tumor: epigenetics, cancer and the microenvironment. J. Mammary Gland Biol. Neoplasia 6, 213-221.
    • (2001) J. Mammary Gland Biol. Neoplasia , vol.6 , pp. 213-221
    • Barcellos-Hoff, M.H.1
  • 23
    • 0035999132 scopus 로고    scopus 로고
    • The dominance of the microenvironment in breast and ovarian cancer
    • Roskelley, C. D. and Bissell, M. J. (2002) The dominance of the microenvironment in breast and ovarian cancer. Semin. Cancer Biol. 12, 97-104.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 97-104
    • Roskelley, C.D.1    Bissell, M.J.2
  • 24
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman, J. (1990) What is the evidence that tumors are angiogenesis dependent? J. Natl. Cancer Inst. 82, 4-6.
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 4-6
    • Folkman, J.1
  • 26
    • 0034193258 scopus 로고    scopus 로고
    • Role of extracellular matrix assembly in interstitial transport in solid tumors
    • Netti, P. A., Berk, D. A., Swartz, M. A., Grodzinsky, A. J. and Jain, R. K. (2000) Role of extracellular matrix assembly in interstitial transport in solid tumors. Cancer Res. 60, 2497-2503.
    • (2000) Cancer Res. , vol.60 , pp. 2497-2503
    • Netti, P.A.1    Berk, D.A.2    Swartz, M.A.3    Grodzinsky, A.J.4    Jain, R.K.5
  • 27
    • 79955591914 scopus 로고    scopus 로고
    • Recent advances in apoptosis, mitochondria and drug resistance in cancer cells
    • Indran, I. R., Tufo, G., Pervaiz, S. and Brenner, C. (2011) Recent advances in apoptosis, mitochondria and drug resistance in cancer cells. Biochim. Biophys. Acta. 1807, 735-745.
    • (2011) Biochim. Biophys. Acta. , vol.1807 , pp. 735-745
    • Indran, I.R.1    Tufo, G.2    Pervaiz, S.3    Brenner, C.4
  • 28
    • 77956355233 scopus 로고    scopus 로고
    • Argonaute proteins are key determinants of RNAi efficacy, toxicity and persistence in the adult mouse liver
    • Grimm, D., Wang, L., Lee, J. S., Schurmann, N., Gu, S., Borner, K., Storm, T. A. and Kay, M. A. (2010) Argonaute proteins are key determinants of RNAi efficacy, toxicity and persistence in the adult mouse liver. J. Clin. Invest. 120, 3106-3119.
    • (2010) J. Clin. Invest. , vol.120 , pp. 3106-3119
    • Grimm, D.1    Wang, L.2    Lee, J.S.3    Schurmann, N.4    Gu, S.5    Borner, K.6    Storm, T.A.7    Kay, M.A.8
  • 29
    • 78049442950 scopus 로고    scopus 로고
    • Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model
    • Wen, Y., Wang, C. T., Ma, T. T., Li, Z. Y., Zhou, L. N., Mu, B., Leng, F., Shi, H. S., Li, Y. O. and Wei, Y. Q. (2010) Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model. Cancer Sci. 101, 2325-2332.
    • (2010) Cancer Sci. , vol.101 , pp. 2325-2332
    • Wen, Y.1    Wang, C.T.2    Ma, T.T.3    Li, Z.Y.4    Zhou, L.N.5    Mu, B.6    Leng, F.7    Shi, H.S.8    Li, Y.O.9    Wei, Y.Q.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.