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Volumn 47-48, Issue , 2015, Pages 101-109

Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells

Author keywords

Embryogenesis; Mouse; Signalling; Stem cells; Wnt signalling

Indexed keywords

BETA CATENIN; TRANSCRIPTION FACTOR; WNT PROTEIN;

EID: 84952638414     PISSN: 10849521     EISSN: 10963634     Source Type: Journal    
DOI: 10.1016/j.semcdb.2015.08.011     Document Type: Review
Times cited : (34)

References (127)
  • 1
    • 40949135002 scopus 로고    scopus 로고
    • Inactivation of nuclear Wnt-beta-catenin signaling limits blastocyst competency for implantation
    • Xie H., Tranguch S., Jia X., Zhang H., Das S.K., Dey S.K., et al. Inactivation of nuclear Wnt-beta-catenin signaling limits blastocyst competency for implantation. Development 2008, 135:717-727.
    • (2008) Development , vol.135 , pp. 717-727
    • Xie, H.1    Tranguch, S.2    Jia, X.3    Zhang, H.4    Das, S.K.5    Dey, S.K.6
  • 2
    • 84891426893 scopus 로고    scopus 로고
    • Zygotic porcn paternal allele deletion in mice to model human focal dermal hypoplasia
    • Biechele S., Adissu H.A., Cox B.J., Rossant J. Zygotic porcn paternal allele deletion in mice to model human focal dermal hypoplasia. PLoS ONE 2013, 8:e79139.
    • (2013) PLoS ONE , vol.8
    • Biechele, S.1    Adissu, H.A.2    Cox, B.J.3    Rossant, J.4
  • 3
    • 0021358883 scopus 로고
    • Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
    • Bradley A., Evans M., Kaufman M.H., Robertson E. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 1984, 309:255-256.
    • (1984) Nature , vol.309 , pp. 255-256
    • Bradley, A.1    Evans, M.2    Kaufman, M.H.3    Robertson, E.4
  • 4
    • 0035189927 scopus 로고    scopus 로고
    • Embryo-derived stem cells: of mice and men
    • Smith A.G. Embryo-derived stem cells: of mice and men. Annu. Rev. Cell Dev. Biol. 2001, 17:435-462.
    • (2001) Annu. Rev. Cell Dev. Biol. , vol.17 , pp. 435-462
    • Smith, A.G.1
  • 5
    • 78650730724 scopus 로고    scopus 로고
    • The origin and identity of embryonic stem cells
    • Nichols J., Smith A. The origin and identity of embryonic stem cells. Development 2011, 138:3-8.
    • (2011) Development , vol.138 , pp. 3-8
    • Nichols, J.1    Smith, A.2
  • 6
    • 84867865709 scopus 로고    scopus 로고
    • In vitro organogenesis in three dimensions: self-organising stem cells
    • Sasai Y., Eiraku M., Suga H. In vitro organogenesis in three dimensions: self-organising stem cells. Development 2012, 139:4111-4121.
    • (2012) Development , vol.139 , pp. 4111-4121
    • Sasai, Y.1    Eiraku, M.2    Suga, H.3
  • 7
    • 84904396621 scopus 로고    scopus 로고
    • Organogenesis in a dish: modeling development and disease using organoid technologies
    • Lancaster M.A., Knoblich J.A. Organogenesis in a dish: modeling development and disease using organoid technologies. Science 2014, 345:1247125.
    • (2014) Science , vol.345 , pp. 1247125
    • Lancaster, M.A.1    Knoblich, J.A.2
  • 10
    • 65549115574 scopus 로고    scopus 로고
    • Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse
    • Rossant J., Tam P.P. Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse. Development 2009, 136:701-713.
    • (2009) Development , vol.136 , pp. 701-713
    • Rossant, J.1    Tam, P.P.2
  • 11
    • 84881599904 scopus 로고    scopus 로고
    • A molecular basis for developmental plasticity in early mammalian embryos
    • Martinez Arias A., Nichols J., Schroter C. A molecular basis for developmental plasticity in early mammalian embryos. Development 2013, 140:3499-3510.
    • (2013) Development , vol.140 , pp. 3499-3510
    • Martinez Arias, A.1    Nichols, J.2    Schroter, C.3
  • 12
    • 84876727460 scopus 로고    scopus 로고
    • Anatomy of a blastocyst: cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo
    • Schrode N., Xenopoulos P., Piliszek A., Frankenberg S., Plusa B., Hadjantonakis A.K. Anatomy of a blastocyst: cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo. Genesis 2013, 51:219-233.
    • (2013) Genesis , vol.51 , pp. 219-233
    • Schrode, N.1    Xenopoulos, P.2    Piliszek, A.3    Frankenberg, S.4    Plusa, B.5    Hadjantonakis, A.K.6
  • 13
    • 0033593571 scopus 로고    scopus 로고
    • Axis development and early asymmetry in mammals
    • Beddington R.S., Robertson E.J. Axis development and early asymmetry in mammals. Cell 1999, 96:195-209.
    • (1999) Cell , vol.96 , pp. 195-209
    • Beddington, R.S.1    Robertson, E.J.2
  • 14
    • 3242722012 scopus 로고    scopus 로고
    • Diversity of germ layer and axis formation among mammals
    • Eakin G.S., Behringer R.R. Diversity of germ layer and axis formation among mammals. Semin. Cell Dev. Biol. 2004, 15:619-629.
    • (2004) Semin. Cell Dev. Biol. , vol.15 , pp. 619-629
    • Eakin, G.S.1    Behringer, R.R.2
  • 15
    • 58849097959 scopus 로고    scopus 로고
    • Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo
    • Arnold S.J., Robertson E.J. Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. Nat. Rev. Mol. Cell Biol. 2009, 10:91-103.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 91-103
    • Arnold, S.J.1    Robertson, E.J.2
  • 16
    • 83755186011 scopus 로고    scopus 로고
    • Clonal and molecular analysis of the prospective anterior neural boundary in the mouse embryo
    • Cajal M., Lawson K.A., Hill B., Moreau A., Rao J., Ross A., et al. Clonal and molecular analysis of the prospective anterior neural boundary in the mouse embryo. Development 2012, 139:423-436.
    • (2012) Development , vol.139 , pp. 423-436
    • Cajal, M.1    Lawson, K.A.2    Hill, B.3    Moreau, A.4    Rao, J.5    Ross, A.6
  • 17
    • 0025942116 scopus 로고
    • Clonal analysis of epiblast fate during germ layer formation in the mouse embryo
    • Lawson K.A., Meneses J.J., Pedersen R.A. Clonal analysis of epiblast fate during germ layer formation in the mouse embryo. Development 1991, 113:891-911.
    • (1991) Development , vol.113 , pp. 891-911
    • Lawson, K.A.1    Meneses, J.J.2    Pedersen, R.A.3
  • 19
    • 84864203741 scopus 로고    scopus 로고
    • Initiating head development in mouse embryos: integrating signalling and transcriptional activity
    • Arkell R.M., Tam P.P. Initiating head development in mouse embryos: integrating signalling and transcriptional activity. Open Biol. 2012, 2:120030.
    • (2012) Open Biol. , vol.2 , pp. 120030
    • Arkell, R.M.1    Tam, P.P.2
  • 20
    • 0030926093 scopus 로고    scopus 로고
    • The allocation of epiblast cells to the embryonic heart and other mesodermal lineages: the role of ingression and tissue movement during gastrulation
    • Tam P.P., Parameswaran M., Kinder S.J., Weinberger R.P. The allocation of epiblast cells to the embryonic heart and other mesodermal lineages: the role of ingression and tissue movement during gastrulation. Development 1997, 124:1631-1642.
    • (1997) Development , vol.124 , pp. 1631-1642
    • Tam, P.P.1    Parameswaran, M.2    Kinder, S.J.3    Weinberger, R.P.4
  • 21
    • 0029117833 scopus 로고
    • Regionalisation of cell fate and morphogenetic movement of the mesoderm during mouse gastrulation
    • Parameswaran M., Tam P.P. Regionalisation of cell fate and morphogenetic movement of the mesoderm during mouse gastrulation. Dev. Genet. 1995, 17:16-28.
    • (1995) Dev. Genet. , vol.17 , pp. 16-28
    • Parameswaran, M.1    Tam, P.P.2
  • 22
    • 0026494353 scopus 로고
    • Clonal analysis of cell fate during gastrulation and early neurulation in the mouse
    • (Discussion-6)
    • Lawson K.A., Pedersen R.A. Clonal analysis of cell fate during gastrulation and early neurulation in the mouse. Ciba Found. Symp. 1992, 165:3-21. (Discussion-6).
    • (1992) Ciba Found. Symp. , vol.165 , pp. 3-21
    • Lawson, K.A.1    Pedersen, R.A.2
  • 23
    • 79960026099 scopus 로고    scopus 로고
    • Origin and role of distal visceral endoderm, a group of cells that determines anterior-posterior polarity of the mouse embryo
    • Takaoka K., Yamamoto M., Hamada H. Origin and role of distal visceral endoderm, a group of cells that determines anterior-posterior polarity of the mouse embryo. Nat. Cell Biol. 2011, 13:743-752.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 743-752
    • Takaoka, K.1    Yamamoto, M.2    Hamada, H.3
  • 24
    • 34247226529 scopus 로고    scopus 로고
    • Gene function in mouse embryogenesis: get set for gastrulation
    • Tam P.P., Loebel D.A. Gene function in mouse embryogenesis: get set for gastrulation. Nat. Rev. Genet. 2007, 8:368-381.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 368-381
    • Tam, P.P.1    Loebel, D.A.2
  • 25
    • 33947656333 scopus 로고    scopus 로고
    • Nodal signaling: developmental roles and regulation
    • Shen M.M. Nodal signaling: developmental roles and regulation. Development 2007, 134:1023-1034.
    • (2007) Development , vol.134 , pp. 1023-1034
    • Shen, M.M.1
  • 26
    • 33747842468 scopus 로고    scopus 로고
    • The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4
    • Ben-Haim N., Lu C., Guzman-Ayala M., Pescatore L., Mesnard D., Bischofberger M., et al. The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4. Dev. Cell 2006, 11:313-323.
    • (2006) Dev. Cell , vol.11 , pp. 313-323
    • Ben-Haim, N.1    Lu, C.2    Guzman-Ayala, M.3    Pescatore, L.4    Mesnard, D.5    Bischofberger, M.6
  • 28
    • 33745256758 scopus 로고    scopus 로고
    • Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo
    • Camus A., Perea-Gomez A., Moreau A., Collignon J. Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo. Dev. Biol. 2006, 295:743-755.
    • (2006) Dev. Biol. , vol.295 , pp. 743-755
    • Camus, A.1    Perea-Gomez, A.2    Moreau, A.3    Collignon, J.4
  • 29
    • 84866478641 scopus 로고    scopus 로고
    • Differential requirements for beta-catenin during mouse development
    • Rudloff S., Kemler R. Differential requirements for beta-catenin during mouse development. Development 2012, 139:3711-3721.
    • (2012) Development , vol.139 , pp. 3711-3721
    • Rudloff, S.1    Kemler, R.2
  • 30
    • 2342644075 scopus 로고    scopus 로고
    • BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning
    • Davis S., Miura S., Hill C., Mishina Y., Klingensmith J. BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning. Dev. Biol. 2004, 270:47-63.
    • (2004) Dev. Biol. , vol.270 , pp. 47-63
    • Davis, S.1    Miura, S.2    Hill, C.3    Mishina, Y.4    Klingensmith, J.5
  • 31
    • 79951520988 scopus 로고    scopus 로고
    • Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo
    • Fossat N., Jones V., Khoo P.L., Bogani D., Hardy A., Steiner K., et al. Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo. Development 2011, 138:667-676.
    • (2011) Development , vol.138 , pp. 667-676
    • Fossat, N.1    Jones, V.2    Khoo, P.L.3    Bogani, D.4    Hardy, A.5    Steiner, K.6
  • 32
    • 84908398512 scopus 로고    scopus 로고
    • Wnt/beta-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells
    • Turner D.A., Hayward P.C., Baillie-Johnson P., Rue P., Broome R., Faunes F., et al. Wnt/beta-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells. Development 2014, 141:4243-4253.
    • (2014) Development , vol.141 , pp. 4243-4253
    • Turner, D.A.1    Hayward, P.C.2    Baillie-Johnson, P.3    Rue, P.4    Broome, R.5    Faunes, F.6
  • 33
    • 84874512754 scopus 로고    scopus 로고
    • A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells
    • Faunes F., Hayward P., Muñoz-Descalzo S., Chatterjee S.S., Balayo T., Trott J., et al. A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells. Development 2013, 140:1171-1183.
    • (2013) Development , vol.140 , pp. 1171-1183
    • Faunes, F.1    Hayward, P.2    Muñoz-Descalzo, S.3    Chatterjee, S.S.4    Balayo, T.5    Trott, J.6
  • 34
    • 84894876824 scopus 로고    scopus 로고
    • A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells
    • Munoz Descalzo S., Rue P., Faunes F., Hayward P., Jakt L.M., Balayo T., et al. A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells. Mol. Syst. Biol. 2013, 9:694.
    • (2013) Mol. Syst. Biol. , vol.9 , pp. 694
    • Munoz Descalzo, S.1    Rue, P.2    Faunes, F.3    Hayward, P.4    Jakt, L.M.5    Balayo, T.6
  • 35
    • 33750955250 scopus 로고    scopus 로고
    • Knockout mouse models to study Wnt signal transduction
    • van Amerongen R., Berns A. Knockout mouse models to study Wnt signal transduction. Trends Genet. 2006, 22:678-689.
    • (2006) Trends Genet. , vol.22 , pp. 678-689
    • van Amerongen, R.1    Berns, A.2
  • 36
    • 20744445658 scopus 로고    scopus 로고
    • Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development
    • Kemp C., Willems E., Abdo S., Lambiv L., Leyns L. Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development. Dev. Dyn. 2005, 233:1064-1075.
    • (2005) Dev. Dyn. , vol.233 , pp. 1064-1075
    • Kemp, C.1    Willems, E.2    Abdo, S.3    Lambiv, L.4    Leyns, L.5
  • 39
    • 10744230854 scopus 로고    scopus 로고
    • Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation
    • Morkel M., Huelsken J., Wakamiya M., Ding J., van de Wetering M., Clevers H., et al. Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation. Development 2003, 130:6283-6294.
    • (2003) Development , vol.130 , pp. 6283-6294
    • Morkel, M.1    Huelsken, J.2    Wakamiya, M.3    Ding, J.4    van de Wetering, M.5    Clevers, H.6
  • 42
    • 78650814119 scopus 로고    scopus 로고
    • Nodal cis-regulatory elements reveal epiblast and primitive endoderm heterogeneity in the peri-implantation mouse embryo
    • Granier C., Gurchenkov V., Perea-Gomez A., Camus A., Ott S., Papanayotou C., et al. Nodal cis-regulatory elements reveal epiblast and primitive endoderm heterogeneity in the peri-implantation mouse embryo. Dev. Biol. 2011, 349:350-362.
    • (2011) Dev. Biol. , vol.349 , pp. 350-362
    • Granier, C.1    Gurchenkov, V.2    Perea-Gomez, A.3    Camus, A.4    Ott, S.5    Papanayotou, C.6
  • 43
    • 84880314645 scopus 로고    scopus 로고
    • Wnt/beta-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse
    • Engert S., Burtscher I., Liao W.P., Dulev S., Schotta G., Lickert H. Wnt/beta-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse. Development 2013, 140:3128-3138.
    • (2013) Development , vol.140 , pp. 3128-3138
    • Engert, S.1    Burtscher, I.2    Liao, W.P.3    Dulev, S.4    Schotta, G.5    Lickert, H.6
  • 44
    • 0036696415 scopus 로고    scopus 로고
    • Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm
    • Lickert H., Kutsch S., Kanzler B., Tamai Y., Taketo M.M., Kemler R. Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm. Dev. Cell 2002, 3:171-181.
    • (2002) Dev. Cell , vol.3 , pp. 171-181
    • Lickert, H.1    Kutsch, S.2    Kanzler, B.3    Tamai, Y.4    Taketo, M.M.5    Kemler, R.6
  • 45
    • 0032531946 scopus 로고    scopus 로고
    • Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo
    • Ding J., Yang L., Yan Y.T., Chen A., Desai N., Wynshaw-Boris A., et al. Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo. Nature 1998, 395:702-707.
    • (1998) Nature , vol.395 , pp. 702-707
    • Ding, J.1    Yang, L.2    Yan, Y.T.3    Chen, A.4    Desai, N.5    Wynshaw-Boris, A.6
  • 46
    • 0030804761 scopus 로고    scopus 로고
    • A specific domain in alpha-catenin mediates binding to beta-catenin or plakoglobin
    • Huber O., Krohn M., Kemler R. A specific domain in alpha-catenin mediates binding to beta-catenin or plakoglobin. J. Cell Sci. 1997, 110(Pt 15):1759-1765.
    • (1997) J. Cell Sci. , vol.110 , pp. 1759-1765
    • Huber, O.1    Krohn, M.2    Kemler, R.3
  • 47
    • 12344308348 scopus 로고    scopus 로고
    • Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast
    • Kemler R., Hierholzer A., Kanzler B., Kuppig S., Hansen K., Taketo M.M., et al. Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast. Development 2004, 131:5817-5824.
    • (2004) Development , vol.131 , pp. 5817-5824
    • Kemler, R.1    Hierholzer, A.2    Kanzler, B.3    Kuppig, S.4    Hansen, K.5    Taketo, M.M.6
  • 48
    • 84879676304 scopus 로고    scopus 로고
    • Porcn-dependent Wnt signaling is not required prior to mouse gastrulation
    • Biechele S., Cockburn K., Lanner F., Cox B.J., Rossant J. Porcn-dependent Wnt signaling is not required prior to mouse gastrulation. Development 2013, 140:2961-2971.
    • (2013) Development , vol.140 , pp. 2961-2971
    • Biechele, S.1    Cockburn, K.2    Lanner, F.3    Cox, B.J.4    Rossant, J.5
  • 49
    • 79959281790 scopus 로고    scopus 로고
    • Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos
    • Biechele S., Cox B.J., Rossant J. Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos. Dev. Biol. 2011, 355:275-285.
    • (2011) Dev. Biol. , vol.355 , pp. 275-285
    • Biechele, S.1    Cox, B.J.2    Rossant, J.3
  • 50
    • 2342441840 scopus 로고    scopus 로고
    • The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice
    • Kelly O.G., Pinson K.I., Skarnes W.C. The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice. Development 2004, 131:2803-2815.
    • (2004) Development , vol.131 , pp. 2803-2815
    • Kelly, O.G.1    Pinson, K.I.2    Skarnes, W.C.3
  • 51
    • 27644590039 scopus 로고    scopus 로고
    • Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm
    • Kimura-Yoshida C., Nakano H., Okamura D., Nakao K., Yonemura S., Belo J.A., et al. Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm. Dev. Cell 2005, 9:639-650.
    • (2005) Dev. Cell , vol.9 , pp. 639-650
    • Kimura-Yoshida, C.1    Nakano, H.2    Okamura, D.3    Nakao, K.4    Yonemura, S.5    Belo, J.A.6
  • 53
    • 0037314332 scopus 로고    scopus 로고
    • Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge
    • Barrow J.R., Thomas K.R., Boussadia-Zahui O., Moore R., Kemler R., Capecchi M.R., et al. Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev. 2003, 17:394-409.
    • (2003) Genes Dev. , vol.17 , pp. 394-409
    • Barrow, J.R.1    Thomas, K.R.2    Boussadia-Zahui, O.3    Moore, R.4    Kemler, R.5    Capecchi, M.R.6
  • 54
    • 29044447949 scopus 로고    scopus 로고
    • Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3
    • Rivera-Perez J.A., Magnuson T. Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3. Dev. Biol. 2005, 288:363-371.
    • (2005) Dev. Biol. , vol.288 , pp. 363-371
    • Rivera-Perez, J.A.1    Magnuson, T.2
  • 56
    • 0035902512 scopus 로고    scopus 로고
    • Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression
    • Galceran J., Hsu S.C., Grosschedl R. Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:8668-8673.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 8668-8673
    • Galceran, J.1    Hsu, S.C.2    Grosschedl, R.3
  • 57
    • 84855805936 scopus 로고    scopus 로고
    • Wnt-Notch signalling: an integrated mechanism regulating transitions between cell states
    • Munoz-Descalzo S., de Navascues J., Arias A.M. Wnt-Notch signalling: an integrated mechanism regulating transitions between cell states. Bioessays 2012, 34:110-118.
    • (2012) Bioessays , vol.34 , pp. 110-118
    • Munoz-Descalzo, S.1    de Navascues, J.2    Arias, A.M.3
  • 58
    • 29244476917 scopus 로고    scopus 로고
    • Filtering transcriptional noise during development: concepts and mechanisms
    • Martinez Arias A.M., Hayward P. Filtering transcriptional noise during development: concepts and mechanisms. Nat. Rev. Genet. 2006, 7:34-44.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 34-44
    • Martinez Arias, A.M.1    Hayward, P.2
  • 59
    • 3343002128 scopus 로고    scopus 로고
    • The mouse frizzled 8 receptor is expressed in anterior organizer tissues
    • Lu C.C., Robertson E.J., Brennan J. The mouse frizzled 8 receptor is expressed in anterior organizer tissues. Gene Expr. Patterns 2004, 4:569-572.
    • (2004) Gene Expr. Patterns , vol.4 , pp. 569-572
    • Lu, C.C.1    Robertson, E.J.2    Brennan, J.3
  • 60
    • 34447502405 scopus 로고    scopus 로고
    • Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling
    • Kemp C.R., Willems E., Wawrzak D., Hendrickx M., Agbor Agbor T., Leyns L. Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling. Dev. Dyn. 2007, 236:2011-2019.
    • (2007) Dev. Dyn. , vol.236 , pp. 2011-2019
    • Kemp, C.R.1    Willems, E.2    Wawrzak, D.3    Hendrickx, M.4    Agbor Agbor, T.5    Leyns, L.6
  • 61
    • 0032588683 scopus 로고    scopus 로고
    • Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development
    • Bhanot P., Fish M., Jemison J.A., Nusse R., Nathans J., Cadigan K.M. Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development. Development 1999, 126:4175-4186.
    • (1999) Development , vol.126 , pp. 4175-4186
    • Bhanot, P.1    Fish, M.2    Jemison, J.A.3    Nusse, R.4    Nathans, J.5    Cadigan, K.M.6
  • 62
    • 57149114315 scopus 로고    scopus 로고
    • Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development
    • Etheridge S.L., Ray S., Li S., Hamblet N.S., Lijam N., Tsang M., et al. Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet. 2008, 4:e1000259.
    • (2008) PLoS Genet. , vol.4
    • Etheridge, S.L.1    Ray, S.2    Li, S.3    Hamblet, N.S.4    Lijam, N.5    Tsang, M.6
  • 63
    • 84868639059 scopus 로고    scopus 로고
    • Dishevelled: In vivo roles of a multifunctional gene family during development
    • Wynshaw-Boris A., Dishevelled: in vivo roles of a multifunctional gene family during development. Curr. Top. Dev. Biol. 2012, 101:213-235.
    • (2012) Curr. Top. Dev. Biol. , vol.101 , pp. 213-235
    • Wynshaw-Boris, A.1
  • 64
    • 33646527782 scopus 로고    scopus 로고
    • Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway
    • Chazaud C., Yamanaka Y., Pawson T., Rossant J. Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev. Cell 2006, 10:615-624.
    • (2006) Dev. Cell , vol.10 , pp. 615-624
    • Chazaud, C.1    Yamanaka, Y.2    Pawson, T.3    Rossant, J.4
  • 65
    • 0029125021 scopus 로고
    • Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation
    • Moser A.R., Shoemaker A.R., Connelly C.S., Clipson L., Gould K.A., Luongo C., et al. Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation. Dev. Dyn. 1995, 203:422-433.
    • (1995) Dev. Dyn. , vol.203 , pp. 422-433
    • Moser, A.R.1    Shoemaker, A.R.2    Connelly, C.S.3    Clipson, L.4    Gould, K.A.5    Luongo, C.6
  • 66
    • 0031457978 scopus 로고    scopus 로고
    • The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation
    • Zeng L., Fagotto F., Zhang T., Hsu W., Vasicek T.J., Perry W.L., et al. The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell 1997, 90:181-192.
    • (1997) Cell , vol.90 , pp. 181-192
    • Zeng, L.1    Fagotto, F.2    Zhang, T.3    Hsu, W.4    Vasicek, T.J.5    Perry, W.L.6
  • 67
    • 18944388680 scopus 로고    scopus 로고
    • Mouse axin and axin2/conductin proteins are functionally equivalent in vivo
    • Chia I.V., Costantini F. Mouse axin and axin2/conductin proteins are functionally equivalent in vivo. Mol. Cell. Biol. 2005, 25:4371-4376.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 4371-4376
    • Chia, I.V.1    Costantini, F.2
  • 68
    • 79957682427 scopus 로고    scopus 로고
    • Tissue-specific roles of Axin2 in the inhibition and activation of Wnt signaling in the mouse embryo
    • Qian L., Mahaffey J.P., Alcorn H.L., Anderson K.V. Tissue-specific roles of Axin2 in the inhibition and activation of Wnt signaling in the mouse embryo. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:8692-8697.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 8692-8697
    • Qian, L.1    Mahaffey, J.P.2    Alcorn, H.L.3    Anderson, K.V.4
  • 69
    • 0034612636 scopus 로고    scopus 로고
    • Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
    • Hoeflich K.P., Luo J., Rubie E.A., Tsao M.S., Jin O., Woodgett J.R. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 2000, 406:86-90.
    • (2000) Nature , vol.406 , pp. 86-90
    • Hoeflich, K.P.1    Luo, J.2    Rubie, E.A.3    Tsao, M.S.4    Jin, O.5    Woodgett, J.R.6
  • 70
    • 34548841091 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism
    • MacAulay K., Doble B.W., Patel S., Hansotia T., Sinclair E.M., Drucker D.J., et al. Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism. Cell Metab. 2007, 6:329-337.
    • (2007) Cell Metab. , vol.6 , pp. 329-337
    • MacAulay, K.1    Doble, B.W.2    Patel, S.3    Hansotia, T.4    Sinclair, E.M.5    Drucker, D.J.6
  • 71
    • 62849106337 scopus 로고    scopus 로고
    • Beta-catenin hits chromatin: regulation of Wnt target gene activation
    • Mosimann C., Hausmann G., Basler K. Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat. Rev. Mol. Cell Biol. 2009, 10:276-286.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 276-286
    • Mosimann, C.1    Hausmann, G.2    Basler, K.3
  • 72
    • 55649088107 scopus 로고    scopus 로고
    • A Wnt-fall for gene regulation: repression
    • Hoverter N.P., Waterman M.L. A Wnt-fall for gene regulation: repression. Sci. Signal. 2008, 1:e43.
    • (2008) Sci. Signal. , vol.1
    • Hoverter, N.P.1    Waterman, M.L.2
  • 73
    • 34748896686 scopus 로고    scopus 로고
    • Stem cells and TCF proteins: a role for beta-catenin-independent functions
    • Yi F., Merrill B.J. Stem cells and TCF proteins: a role for beta-catenin-independent functions. Stem Cell Rev. 2007, 3:39-48.
    • (2007) Stem Cell Rev. , vol.3 , pp. 39-48
    • Yi, F.1    Merrill, B.J.2
  • 74
    • 0344820773 scopus 로고    scopus 로고
    • Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice
    • Galceran J., Farinas I., Depew M.J., Clevers H., Grosschedl R. Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice. Genes Dev. 1999, 13:709-717.
    • (1999) Genes Dev. , vol.13 , pp. 709-717
    • Galceran, J.1    Farinas, I.2    Depew, M.J.3    Clevers, H.4    Grosschedl, R.5
  • 76
    • 84902184462 scopus 로고    scopus 로고
    • Reorganization of enhancer patterns in transition from naive to primed pluripotency
    • Buecker C., Srinivasan R., Wu Z., Calo E., Acampora D., Faial T., et al. Reorganization of enhancer patterns in transition from naive to primed pluripotency. Cell Stem Cell 2014, 14:838-853.
    • (2014) Cell Stem Cell , vol.14 , pp. 838-853
    • Buecker, C.1    Srinivasan, R.2    Wu, Z.3    Calo, E.4    Acampora, D.5    Faial, T.6
  • 77
    • 66049117813 scopus 로고    scopus 로고
    • Naive and primed pluripotent states
    • Nichols J., Smith A. Naive and primed pluripotent states. Cell Stem Cell 2009, 4:487-492.
    • (2009) Cell Stem Cell , vol.4 , pp. 487-492
    • Nichols, J.1    Smith, A.2
  • 78
    • 34447528757 scopus 로고    scopus 로고
    • New cell lines from mouse epiblast share defining features with human embryonic stem cells
    • Tesar P.J., Chenoweth J.G., Brook F.A., Davies T.J., Evans E.P., Mack D.L., et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 2007, 448:196-199.
    • (2007) Nature , vol.448 , pp. 196-199
    • Tesar, P.J.1    Chenoweth, J.G.2    Brook, F.A.3    Davies, T.J.4    Evans, E.P.5    Mack, D.L.6
  • 80
    • 84871677729 scopus 로고    scopus 로고
    • In vivo differentiation potential of epiblast stem cells revealed by chimeric embryo formation
    • Huang Y., Osorno R., Tsakiridis A., Wilson V. In vivo differentiation potential of epiblast stem cells revealed by chimeric embryo formation. Cell Rep. 2012, 2:1571-1578.
    • (2012) Cell Rep. , vol.2 , pp. 1571-1578
    • Huang, Y.1    Osorno, R.2    Tsakiridis, A.3    Wilson, V.4
  • 81
    • 84891747616 scopus 로고    scopus 로고
    • The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak
    • Kojima Y., Kaufman-Francis K., Studdert J.B., Steiner K.A., Power M.D., Loebel D.A., et al. The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak. Cell Stem Cell 2014, 14:107-120.
    • (2014) Cell Stem Cell , vol.14 , pp. 107-120
    • Kojima, Y.1    Kaufman-Francis, K.2    Studdert, J.B.3    Steiner, K.A.4    Power, M.D.5    Loebel, D.A.6
  • 84
    • 33845996890 scopus 로고    scopus 로고
    • Beta-catenin up-regulates Nanog expression through interaction with Oct-3/4 in embryonic stem cells
    • Takao Y., Yokota T., Koide H. Beta-catenin up-regulates Nanog expression through interaction with Oct-3/4 in embryonic stem cells. Biochem. Biophys. Res. Commun. 2007, 353:699-705.
    • (2007) Biochem. Biophys. Res. Commun. , vol.353 , pp. 699-705
    • Takao, Y.1    Yokota, T.2    Koide, H.3
  • 85
    • 78149337402 scopus 로고    scopus 로고
    • Canonical Wnt/beta-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression
    • Wagner R.T., Xu X., Yi F., Merrill B.J., Cooney A.J. Canonical Wnt/beta-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression. Stem Cells 2010, 28:1794-1804.
    • (2010) Stem Cells , vol.28 , pp. 1794-1804
    • Wagner, R.T.1    Xu, X.2    Yi, F.3    Merrill, B.J.4    Cooney, A.J.5
  • 86
    • 58549109668 scopus 로고    scopus 로고
    • Involvement of GSK-3 in regulation of murine embryonic stem cell self-renewal revealed by a series of bisindolylmaleimides
    • Bone H.K., Damiano T., Bartlett S., Perry A., Letchford J., Ripoll Y.S., et al. Involvement of GSK-3 in regulation of murine embryonic stem cell self-renewal revealed by a series of bisindolylmaleimides. Chem. Biol. 2009, 16:15-27.
    • (2009) Chem. Biol. , vol.16 , pp. 15-27
    • Bone, H.K.1    Damiano, T.2    Bartlett, S.3    Perry, A.4    Letchford, J.5    Ripoll, Y.S.6
  • 88
    • 77952031756 scopus 로고    scopus 로고
    • Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability
    • Kiyonari H., Kaneko M., Abe S., Aizawa S. Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability. Genesis 2010, 48:317-327.
    • (2010) Genesis , vol.48 , pp. 317-327
    • Kiyonari, H.1    Kaneko, M.2    Abe, S.3    Aizawa, S.4
  • 89
    • 36248969284 scopus 로고    scopus 로고
    • Efficient derivation of embryonic stem cells by inhibition of glycogen synthase kinase-3
    • Umehara H., Kimura T., Ohtsuka S., Nakamura T., Kitajima K., Ikawa M., et al. Efficient derivation of embryonic stem cells by inhibition of glycogen synthase kinase-3. Stem Cells 2007, 25:2705-2711.
    • (2007) Stem Cells , vol.25 , pp. 2705-2711
    • Umehara, H.1    Kimura, T.2    Ohtsuka, S.3    Nakamura, T.4    Kitajima, K.5    Ikawa, M.6
  • 90
    • 84859940340 scopus 로고    scopus 로고
    • Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains
    • Ye S., Tan L., Yang R., Fang B., Qu S., Schulze E.N., et al. Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains. PLoS ONE 2012, 7:e35892.
    • (2012) PLoS ONE , vol.7
    • Ye, S.1    Tan, L.2    Yang, R.3    Fang, B.4    Qu, S.5    Schulze, E.N.6
  • 91
    • 70349177792 scopus 로고    scopus 로고
    • Stable generation of serum- and feeder-free embryonic stem cell-derived mice with full germline-competency by using a GSK3 specific inhibitor
    • Sato H., Amagai K., Shimizukawa R., Tamai Y. Stable generation of serum- and feeder-free embryonic stem cell-derived mice with full germline-competency by using a GSK3 specific inhibitor. Genesis 2009, 47:414-422.
    • (2009) Genesis , vol.47 , pp. 414-422
    • Sato, H.1    Amagai, K.2    Shimizukawa, R.3    Tamai, Y.4
  • 92
    • 84887949248 scopus 로고    scopus 로고
    • Tuning of beta-catenin activity is required to stabilize self-renewal of rat embryonic stem cells
    • Meek S., Wei J., Sutherland L., Nilges B., Buehr M., Tomlinson S.R., et al. Tuning of beta-catenin activity is required to stabilize self-renewal of rat embryonic stem cells. Stem Cells 2013, 31:2104-2115.
    • (2013) Stem Cells , vol.31 , pp. 2104-2115
    • Meek, S.1    Wei, J.2    Sutherland, L.3    Nilges, B.4    Buehr, M.5    Tomlinson, S.R.6
  • 93
    • 57649181379 scopus 로고    scopus 로고
    • Capture of authentic embryonic stem cells from rat blastocysts
    • Buehr M., Meek S., Blair K., Yang J., Ure J., Silva J., et al. Capture of authentic embryonic stem cells from rat blastocysts. Cell 2008, 135:1287-1298.
    • (2008) Cell , vol.135 , pp. 1287-1298
    • Buehr, M.1    Meek, S.2    Blair, K.3    Yang, J.4    Ure, J.5    Silva, J.6
  • 94
    • 84920875111 scopus 로고    scopus 로고
    • Endogenous WNT signals mediate BMP-induced and spontaneous differentiation of epiblast stem cells and human embryonic stem cells
    • Kurek D., Neagu A., Tastemel M., Tuysuz N., Lehmann J., Van de Werken H.J., et al. Endogenous WNT signals mediate BMP-induced and spontaneous differentiation of epiblast stem cells and human embryonic stem cells. Stem Cell Rep. 2015, 4:114-128.
    • (2015) Stem Cell Rep. , vol.4 , pp. 114-128
    • Kurek, D.1    Neagu, A.2    Tastemel, M.3    Tuysuz, N.4    Lehmann, J.5    Van de Werken, H.J.6
  • 95
    • 43049144313 scopus 로고    scopus 로고
    • Wnt signaling stem cell control
    • Nusse R. Wnt signaling stem cell control. Cell Res. 2008, 18:523-527.
    • (2008) Cell Res. , vol.18 , pp. 523-527
    • Nusse, R.1
  • 96
    • 80052475509 scopus 로고    scopus 로고
    • Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
    • Berge D.T., Kurek D., Blauwkamp T., Koole W., Maas A., Eroglu E., et al. Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells. Nat. Cell Biol. 2011, 13:1070-1075.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 1070-1075
    • Berge, D.T.1    Kurek, D.2    Blauwkamp, T.3    Koole, W.4    Maas, A.5    Eroglu, E.6
  • 97
    • 84874451266 scopus 로고    scopus 로고
    • Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue
    • Ardehali R., Ali S.R., Inlay M.A., Abilez O.J., Chen M.Q., Blauwkamp T.A., et al. Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:3405-3410.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 3405-3410
    • Ardehali, R.1    Ali, S.R.2    Inlay, M.A.3    Abilez, O.J.4    Chen, M.Q.5    Blauwkamp, T.A.6
  • 98
    • 18744398990 scopus 로고    scopus 로고
    • Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling
    • Kielman M.F., Rindapaa M., Gaspar C., van Poppel N., Breukel C., van Leeuwen S., et al. Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling. Nat. Genet. 2002, 32:594-605.
    • (2002) Nat. Genet. , vol.32 , pp. 594-605
    • Kielman, M.F.1    Rindapaa, M.2    Gaspar, C.3    van Poppel, N.4    Breukel, C.5    van Leeuwen, S.6
  • 99
    • 33847740988 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in cancer stemness and malignant behavior
    • Fodde R., Brabletz T. Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr. Opin. Cell Biol. 2007, 19:150-158.
    • (2007) Curr. Opin. Cell Biol. , vol.19 , pp. 150-158
    • Fodde, R.1    Brabletz, T.2
  • 100
    • 84878522915 scopus 로고    scopus 로고
    • Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation
    • Atlasi Y., Noori R., Gaspar C., Franken P., Sacchetti A., Rafati H., et al. Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation. PLoS Genet. 2013, 9:e1003424.
    • (2013) PLoS Genet. , vol.9
    • Atlasi, Y.1    Noori, R.2    Gaspar, C.3    Franken, P.4    Sacchetti, A.5    Rafati, H.6
  • 101
    • 84877744686 scopus 로고    scopus 로고
    • Beta-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells
    • Okumura N., Akutsu H., Sugawara T., Miura T., Takezawa Y., Hosoda A., et al. Beta-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells. PLoS ONE 2013, 8:e63265.
    • (2013) PLoS ONE , vol.8
    • Okumura, N.1    Akutsu, H.2    Sugawara, T.3    Miura, T.4    Takezawa, Y.5    Hosoda, A.6
  • 102
    • 79959950773 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
    • Wray J., Kalkan T., Gomez-Lopez S., Eckardt D., Cook A., Kemler R., et al. Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat. Cell Biol. 2011, 13:838-845.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 838-845
    • Wray, J.1    Kalkan, T.2    Gomez-Lopez, S.3    Eckardt, D.4    Cook, A.5    Kemler, R.6
  • 103
    • 79959999016 scopus 로고    scopus 로고
    • Differential requirement for the dual functions of beta-catenin in embryonic stem cell self-renewal and germ layer formation
    • Lyashenko N., Winter M., Migliorini D., Biechele T., Moon R.T., Hartmann C. Differential requirement for the dual functions of beta-catenin in embryonic stem cell self-renewal and germ layer formation. Nat. Cell Biol. 2011, 13:753-761.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 753-761
    • Lyashenko, N.1    Winter, M.2    Migliorini, D.3    Biechele, T.4    Moon, R.T.5    Hartmann, C.6
  • 104
    • 35548941791 scopus 로고    scopus 로고
    • Beta-catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells
    • Anton R., Kestler H.A., Kuhl M. Beta-catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells. FEBS Lett. 2007, 581:5247-5254.
    • (2007) FEBS Lett. , vol.581 , pp. 5247-5254
    • Anton, R.1    Kestler, H.A.2    Kuhl, M.3
  • 105
    • 79959963618 scopus 로고    scopus 로고
    • Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal
    • Yi F., Pereira L., Hoffman J.A., Shy B.R., Yuen C.M., Liu D.R., et al. Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal. Nat. Cell Biol. 2011, 13:62-70.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 62-70
    • Yi, F.1    Pereira, L.2    Hoffman, J.A.3    Shy, B.R.4    Yuen, C.M.5    Liu, D.R.6
  • 106
    • 33749645068 scopus 로고    scopus 로고
    • Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal
    • Pereira L., Yi F., Merrill B.J. Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal. Mol. Cell Biol. 2006, 26:7479-7491.
    • (2006) Mol. Cell Biol. , vol.26 , pp. 7479-7491
    • Pereira, L.1    Yi, F.2    Merrill, B.J.3
  • 107
    • 48449105489 scopus 로고    scopus 로고
    • Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal
    • Yi F., Pereira L., Merrill B.J. Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal. Stem Cells 2008, 26:1951-1960.
    • (2008) Stem Cells , vol.26 , pp. 1951-1960
    • Yi, F.1    Pereira, L.2    Merrill, B.J.3
  • 108
    • 84870312110 scopus 로고    scopus 로고
    • Correlations between the levels of oct4 and nanog as a signature for naive pluripotency in mouse embryonic stem cells
    • Munoz Descalzo S., Rue P., Garcia-Ojalvo J., Arias A.M. Correlations between the levels of oct4 and nanog as a signature for naive pluripotency in mouse embryonic stem cells. Stem Cells 2012, 30:2683-2691.
    • (2012) Stem Cells , vol.30 , pp. 2683-2691
    • Munoz Descalzo, S.1    Rue, P.2    Garcia-Ojalvo, J.3    Arias, A.M.4
  • 109
    • 84875443829 scopus 로고    scopus 로고
    • E-cadherin is required for the proper activation of the Lifr/Gp130 signaling pathway in mouse embryonic stem cells
    • del Valle I., Rudloff S., Carles A., Li Y., Liszewska E., Vogt R., et al. E-cadherin is required for the proper activation of the Lifr/Gp130 signaling pathway in mouse embryonic stem cells. Development 2013, 140:1684-1692.
    • (2013) Development , vol.140 , pp. 1684-1692
    • del Valle, I.1    Rudloff, S.2    Carles, A.3    Li, Y.4    Liszewska, E.5    Vogt, R.6
  • 110
    • 84892442959 scopus 로고    scopus 로고
    • Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/beta-catenin signaling
    • Shy B.R., Wu C.I., Khramtsova G.F., Zhang J.Y., Olopade O.I., Goss K.H., et al. Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/beta-catenin signaling. Cell Rep. 2013, 4:1-9.
    • (2013) Cell Rep. , vol.4 , pp. 1-9
    • Shy, B.R.1    Wu, C.I.2    Khramtsova, G.F.3    Zhang, J.Y.4    Olopade, O.I.5    Goss, K.H.6
  • 111
    • 84879798567 scopus 로고    scopus 로고
    • Gene regulatory networks mediating canonical Wnt signal directed control of pluripotency and differentiation in embryo stem cells
    • Zhang X., Peterson K.A., Liu X.S., McMahon A.P., Ohba S. Gene regulatory networks mediating canonical Wnt signal directed control of pluripotency and differentiation in embryo stem cells. Stem Cells 2013, 31:2667-2679.
    • (2013) Stem Cells , vol.31 , pp. 2667-2679
    • Zhang, X.1    Peterson, K.A.2    Liu, X.S.3    McMahon, A.P.4    Ohba, S.5
  • 112
    • 77957763022 scopus 로고    scopus 로고
    • Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/beta-catenin signalling
    • Abu-Remaileh M., Gerson A., Farago M., Nathan G., Alkalay I., Zins Rousso S., et al. Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/beta-catenin signalling. EMBO J. 2010, 29:3236-3248.
    • (2010) EMBO J. , vol.29 , pp. 3236-3248
    • Abu-Remaileh, M.1    Gerson, A.2    Farago, M.3    Nathan, G.4    Alkalay, I.5    Zins Rousso, S.6
  • 113
    • 79551594937 scopus 로고    scopus 로고
    • Beta-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism
    • Kelly K.F., Ng D.Y., Jayakumaran G., Wood G.A., Koide H., Doble B.W. beta-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism. Cell Stem Cell 2011, 8:214-227.
    • (2011) Cell Stem Cell , vol.8 , pp. 214-227
    • Kelly, K.F.1    Ng, D.Y.2    Jayakumaran, G.3    Wood, G.A.4    Koide, H.5    Doble, B.W.6
  • 114
    • 79953706310 scopus 로고    scopus 로고
    • Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/beta-catenin signaling and competence provider for Brachyury induction
    • Marikawa Y., Tamashiro D.A., Fujita T.C., Alarcon V.B. Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/beta-catenin signaling and competence provider for Brachyury induction. Stem Cells Dev. 2011, 20:621-633.
    • (2011) Stem Cells Dev. , vol.20 , pp. 621-633
    • Marikawa, Y.1    Tamashiro, D.A.2    Fujita, T.C.3    Alarcon, V.B.4
  • 115
    • 84878579948 scopus 로고    scopus 로고
    • A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages
    • Radzisheuskaya A., Le Bin Chia G., Dos Santos R.L., Theunissen T.W., Castro L.F., Nichols J., et al. A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages. Nat. Cell Biol. 2013, 15:579-590.
    • (2013) Nat. Cell Biol. , vol.15 , pp. 579-590
    • Radzisheuskaya, A.1    Le Bin Chia, G.2    Dos Santos, R.L.3    Theunissen, T.W.4    Castro, L.F.5    Nichols, J.6
  • 116
    • 84877297850 scopus 로고    scopus 로고
    • Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog
    • Karwacki-Neisius V., Goke J., Osorno R., Halbritter F., Ng J.H., Weisse A.Y., et al. Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog. Cell Stem Cell 2013, 12:531-545.
    • (2013) Cell Stem Cell , vol.12 , pp. 531-545
    • Karwacki-Neisius, V.1    Goke, J.2    Osorno, R.3    Halbritter, F.4    Ng, J.H.5    Weisse, A.Y.6
  • 117
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H., Miyazaki J., Smith A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet. 2000, 24:372-376.
    • (2000) Nat. Genet. , vol.24 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 118
    • 84907031132 scopus 로고    scopus 로고
    • Beta-catenin is vital for the integrity of mouse embryonic stem cells
    • Raggioli A., Junghans D., Rudloff S., Kemler R. Beta-catenin is vital for the integrity of mouse embryonic stem cells. PLoS ONE 2014, 9:e86691.
    • (2014) PLoS ONE , vol.9
    • Raggioli, A.1    Junghans, D.2    Rudloff, S.3    Kemler, R.4
  • 119
    • 84877779850 scopus 로고    scopus 로고
    • Epiblast ground state is controlled by canonical Wnt/beta-catenin signaling in the postimplantation mouse embryo and epiblast stem cells
    • Sumi T., Oki S., Kitajima K., Meno C. Epiblast ground state is controlled by canonical Wnt/beta-catenin signaling in the postimplantation mouse embryo and epiblast stem cells. PLoS ONE 2013, 8:e63378.
    • (2013) PLoS ONE , vol.8
    • Sumi, T.1    Oki, S.2    Kitajima, K.3    Meno, C.4
  • 120
    • 84858684478 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4
    • Davidson K.C., Adams A.M., Goodson J.M., McDonald C.E., Potter J.C., Berndt J.D., et al. Wnt/beta-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:4485-4490.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 4485-4490
    • Davidson, K.C.1    Adams, A.M.2    Goodson, J.M.3    McDonald, C.E.4    Potter, J.C.5    Berndt, J.D.6
  • 121
    • 84863241921 scopus 로고    scopus 로고
    • Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation
    • Singh A.M., Reynolds D., Cliff T., Ohtsuka S., Mattheyses A.L., Sun Y., et al. Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation. Cell Stem Cell 2012, 10:312-326.
    • (2012) Cell Stem Cell , vol.10 , pp. 312-326
    • Singh, A.M.1    Reynolds, D.2    Cliff, T.3    Ohtsuka, S.4    Mattheyses, A.L.5    Sun, Y.6
  • 122
    • 84920758332 scopus 로고    scopus 로고
    • Successful reprogramming of epiblast stem cells by blocking nuclear localization of beta-catenin
    • Murayama H., Masaki H., Sato H., Hayama T., Yamaguchi T., Nakauchi H. Successful reprogramming of epiblast stem cells by blocking nuclear localization of beta-catenin. Stem Cell Rep. 2015, 4:103-113.
    • (2015) Stem Cell Rep. , vol.4 , pp. 103-113
    • Murayama, H.1    Masaki, H.2    Sato, H.3    Hayama, T.4    Yamaguchi, T.5    Nakauchi, H.6
  • 123
    • 84901758151 scopus 로고    scopus 로고
    • The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification
    • Boroviak T., Loos R., Bertone P., Smith A., Nichols J. The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Nat. Cell Biol. 2014, 16:516-528.
    • (2014) Nat. Cell Biol. , vol.16 , pp. 516-528
    • Boroviak, T.1    Loos, R.2    Bertone, P.3    Smith, A.4    Nichols, J.5
  • 124
    • 84894067021 scopus 로고    scopus 로고
    • Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst
    • Le Bin G.C., Munoz-Descalzo S., Kurowski A., Leitch H., Lou X., Mansfield W., et al. Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development 2014, 141:1001-1010.
    • (2014) Development , vol.141 , pp. 1001-1010
    • Le Bin, G.C.1    Munoz-Descalzo, S.2    Kurowski, A.3    Leitch, H.4    Lou, X.5    Mansfield, W.6
  • 125
    • 84924532692 scopus 로고    scopus 로고
    • Heterogeneities in nanog expression drive stable commitment to pluripotency in the mouse blastocyst
    • S2211-1247; 138-2
    • Xenopoulos P., Kang M., Puliafito A., Di Talia S., Hadjantonakis A.K. Heterogeneities in nanog expression drive stable commitment to pluripotency in the mouse blastocyst. Cell Rep. 2015, S2211-1247; 138-2.
    • (2015) Cell Rep.
    • Xenopoulos, P.1    Kang, M.2    Puliafito, A.3    Di Talia, S.4    Hadjantonakis, A.K.5
  • 126
    • 33749378267 scopus 로고    scopus 로고
    • Disruption of early proximodistal patterning and AVE formation in Apc mutants
    • Chazaud C., Rossant J. Disruption of early proximodistal patterning and AVE formation in Apc mutants. Development 2006, 133:3379-3387.
    • (2006) Development , vol.133 , pp. 3379-3387
    • Chazaud, C.1    Rossant, J.2
  • 127
    • 84907487414 scopus 로고    scopus 로고
    • Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control
    • Clevers H., Loh K.M., Nusse R. Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control. Science 2014, 346:1248012.
    • (2014) Science , vol.346 , pp. 1248012
    • Clevers, H.1    Loh, K.M.2    Nusse, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.