Successful reprogramming of epiblast stem cells by blocking nuclear localization of β-catenin

Stem Cell Reports

Volumn 4, Issue 1, 2015, Pages 103-113

  Murayama, Hideyuki ^a   Masaki, Hideki ^a   Sato, Hideyuki ^a   Hayama, Tomonari ^a   Yamaguchi, Tomoyuki ^a   Nakauchi, Hiromitsu ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CD31 ANTIGEN; FIBROBLAST GROWTH FACTOR 5; LEFT RIGHT DETERMINATION FACTOR; STAT3 PROTEIN; TRANSCRIPTION FACTOR SOX2; UVOMORULIN; WNT PROTEIN; CADHERIN; LEUKEMIA INHIBITORY FACTOR; PROTEIN BINDING; T CELL FACTOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CHIMERA; CONTROLLED STUDY; CYTOPLASM; ECTODERM; EMBRYO; FEMALE; GENE OVEREXPRESSION; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UPREGULATION; WNT SIGNALING PATHWAY; X CHROMOSOME INACTIVATION; ANIMAL; CELL LINE; CYTOLOGY; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE ORDER; GENE VECTOR; GENETICS; GERM LAYER; METABOLISM; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; STEM CELL;

MUS; RATTUS;

ANIMALS; BETA CATENIN; CADHERINS; CELL LINE; CELL NUCLEUS; CELLULAR REPROGRAMMING; EMBRYONIC STEM CELLS; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE ORDER; GENETIC VECTORS; GERM LAYERS; LEUKEMIA INHIBITORY FACTOR; MICE; PROTEIN BINDING; PROTEIN TRANSPORT; RATS; SIGNAL TRANSDUCTION; STEM CELLS; TCF TRANSCRIPTION FACTORS; WNT SIGNALING PATHWAY;

EID: 84920758332     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2014.12.003     Document Type: Article

References (34)

1. S. Bao, F. Tang, X. Li, K. Hayashi, A. Gillich, K. Lao, and M.A. Surani Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells Nature 461 2009 1292 1295
2. I.G. Brons, L.E. Smithers, M.W. Trotter, P. Rugg-Gunn, B. Sun, S.M. Chuva de Sousa Lopes, S.K. Howlett, A. Clarkson, L. Ahrlund-Richter, R.A. Pedersen, and L. Vallier Derivation of pluripotent epiblast stem cells from mammalian embryos Nature 448 2007 191 195
3. B. Chen, M.E. Dodge, W. Tang, J. Lu, Z. Ma, C.W. Fan, S. Wei, W. Hao, J. Kilgore, and N.S. Williams Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer Nat. Chem. Biol. 5 2009 100 107
4. T. Chen, D. Yuan, B. Wei, J. Jiang, J. Kang, K. Ling, Y. Gu, J. Li, L. Xiao, and G. Pei E-cadherin-mediated cell-cell contact is critical for induced pluripotent stem cell generation Stem Cells 28 2010 1315 1325
5. M. Conacci-Sorrell, I. Simcha, T. Ben-Yedidia, J. Blechman, P. Savagner, and A. Ben-Ze'ev Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK J. Cell Biol. 163 2003 847 857
6. I. del Valle, S. Rudloff, A. Carles, Y. Li, E. Liszewska, R. Vogt, and R. Kemler E-cadherin is required for the proper activation of the Lifr/Gp130 signaling pathway in mouse embryonic stem cells Development 140 2013 1684 1692
7. M.J. Evans, and M.H. Kaufman Establishment in culture of pluripotential cells from mouse embryos Nature 292 1981 154 156
8. O. Gafni, L. Weinberger, A.A. Mansour, Y.S. Manor, E. Chomsky, D. Ben-Yosef, Y. Kalma, S. Viukov, I. Maza, and A. Zviran Derivation of novel human ground state naive pluripotent stem cells Nature 504 2013 282 286
9. A. Gillich, S. Bao, N. Grabole, K. Hayashi, M.W. Trotter, V. Pasque, E. Magnúsdóttir, and M.A. Surani Epiblast stem cell-based system reveals reprogramming synergy of germline factors Cell Stem Cell 10 2012 425 439
10. J. Hanna, A.W. Cheng, K. Saha, J. Kim, C.J. Lengner, F. Soldner, J.P. Cassady, J. Muffat, B.W. Carey, and R. Jaenisch Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs Proc. Natl. Acad. Sci. USA 107 2010 9222 9227
11. S.M. Huang, Y.M. Mishina, S. Liu, A. Cheung, F. Stegmeier, G.A. Michaud, O. Charlat, E. Wiellette, Y. Zhang, and S. Wiessner Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling Nature 461 2009 614 620
12. H. Kim, J. Wu, S. Ye, C.I. Tai, X. Zhou, H. Yan, P. Li, M. Pera, and Q.L. Ying Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal Nat. Commun. 4 2013 2403
13. T. Kobayashi, T. Yamaguchi, S. Hamanaka, M. Kato-Itoh, Y. Yamazaki, M. Ibata, H. Sato, Y.S. Lee, J. Usui, and A.S. Knisely Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells Cell 142 2010 787 799
14. W. Li, W. Wei, S. Zhu, J. Zhu, Y. Shi, T. Lin, E. Hao, A. Hayek, H. Deng, and S. Ding Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors Cell Stem Cell 4 2009 16 19
15. G.R. Martin Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells Proc. Natl. Acad. Sci. USA 78 1981 7634 7638
16. J. Nichols, and A. Smith Naive and primed pluripotent states Cell Stem Cell 4 2009 487 492
17. J. Nichols, and Q.L. Ying Derivation and propagation of embryonic stem cells in serum- and feeder-free culture Methods Mol. Biol. 329 2006 91 98
18. H. Niwa, S. Masui, I. Chambers, A.G. Smith, and J. Miyazaki Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells Mol. Cell. Biol. 22 2002 1526 1536
19. K. Ogawa, H. Matsui, S. Ohtsuka, and H. Niwa A novel mechanism for regulating clonal propagation of mouse ES cells Genes Cells 9 2004 471 477
20. S. Ohtsuka, S. Nishikawa-Torikai, and H. Niwa E-cadherin promotes incorporation of mouse epiblast stem cells into normal development PLoS ONE 7 2012 e45220
21. C.Y. Sasaki, H. Lin, P.J. Morin, and D.L. Longo Truncation of the extracellular region abrogrates cell contact but retains the growth-suppressive activity of E-cadherin Cancer Res. 60 2000 7057 7065
22. J. Silva, J. Nichols, T.W. Theunissen, G. Guo, A.L. van Oosten, O. Barrandon, J. Wray, S. Yamanaka, I. Chambers, and A. Smith Nanog is the gateway to the pluripotent ground state Cell 138 2009 722 737
23. A.G. Smith, J.K. Heath, D.D. Donaldson, G.G. Wong, J. Moreau, M. Stahl, and D. Rogers Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides Nature 336 1988 688 690
24. F.J. Staal, Mv. Noort Mv, G.J. Strous, and H.C. Clevers Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin EMBO Rep. 3 2002 63 68
25. A. Stockinger, A. Eger, J. Wolf, H. Beug, and R. Foisner E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity J. Cell Biol. 154 2001 1185 1196
26. P.J. Tesar, J.G. Chenoweth, F.A. Brook, T.J. Davies, E.P. Evans, D.L. Mack, R.L. Gardner, and R.D. McKay New cell lines from mouse epiblast share defining features with human embryonic stem cells Nature 448 2007 196 199
27. Y. Toyooka, D. Shimosato, K. Murakami, K. Takahashi, and H. Niwa Identification and characterization of subpopulations in undifferentiated ES cell culture Development 135 2008 909 918
28. M.T. Veeman, D.C. Slusarski, A. Kaykas, S.H. Louie, and R.T. Moon Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements Curr. Biol. 13 2003 680 685
29. C.B. Ware, A.M. Nelson, B. Mecham, J. Hesson, W. Zhou, E.C. Jonlin, A.J. Jimenez-Caliani, X. Deng, C. Cavanaugh, and S. Cook Derivation of naive human embryonic stem cells Proc. Natl. Acad. Sci. USA 111 2014 4484 4489
30. J. Wray, T. Kalkan, and A.G. Smith The ground state of pluripotency Biochem. Soc. Trans. 38 2010 1027 1032
31. J. Wray, T. Kalkan, S. Gomez-Lopez, D. Eckardt, A. Cook, R. Kemler, and A. Smith Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation Nat. Cell Biol. 13 2011 838 845
32. T. Yamaguchi, S. Hamanaka, A. Kamiya, M. Okabe, M. Kawarai, Y. Wakiyama, A. Umino, T. Hayama, H. Sato, and Y.S. Lee Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming PLoS ONE 7 2012 e41007
33. Q.L. Ying, J. Nichols, I. Chambers, and A. Smith BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3 Cell 115 2003 281 292
34. Q.L. Ying, J. Wray, J. Nichols, L. Batlle-Morera, B. Doble, J. Woodgett, P. Cohen, and A. Smith The ground state of embryonic stem cell self-renewal Nature 453 2008 519 523