A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages

Nature Cell Biology

Volumn 15, Issue 6, 2013, Pages 579-590

  Radzisheuskaya, Aliaksandra ^a   Le Bin Chia, Gloryn ^a   Dos Santos, Rodrigo L ^a,b   Theunissen, Thorold W ^a,d   Castro, L Filipe C ^c   Nichols, Jennifer ^a   Silva, José C R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

^d WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BLASTOCYST; CELL DIFFERENTIATION; CELL LINEAGE; CELL RENEWAL; CONTROLLED STUDY; DOWN REGULATION; ECTODERM; EMBRYO; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; MOUSE; NONHUMAN; OCT4 GENE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DNA BINDING; SOMATIC CELL; TRANSGENE; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; GENE KNOCKOUT TECHNIQUES; HOMEODOMAIN PROTEINS; INDUCED PLURIPOTENT STEM CELLS; MICE; NEURAL STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3;

EID: 84878579948     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2742     Document Type: Article

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