Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo

Development

Volumn 138, Issue 4, 2011, Pages 667-676

  Fossat, Nicolas ^a,b   Jones, Vanessa ^a   Khoo, Poh Lynn ^a   Bogani, Debora ^c   Hardy, Andrea ^c   Steiner, Kirsten ^a   Mukhopadhyay, Mahua ^d   Westphal, Heiner ^d   Nolan, Patrick M ^c   Arkell, Ruth ^c,e   Tam, Patrick P L ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

catenin; Dkk1; ENU mutant; Gene dosage; Head formation; Lrp6; Mouse; WNT signalling

Indexed keywords

BETA CATENIN; DICKKOPF 1 PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; WNT PROTEIN;

ALLELE; ARTICLE; DEVELOPMENT; EMBRYO; FOREBRAIN; GENE MUTATION; GENOTYPE; HEAD FORMATION; HOMOZYGOSITY; INDUCED MUTATION; MOUSE; MOUSE EMBRYO; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ALLELES; ANIMALS; BASE SEQUENCE; BETA CATENIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEAD; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LDL-RECEPTOR RELATED PROTEINS; MICE; MICE, INBRED BALB C; MUTATION; PHENOTYPE; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 79951520988     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.052803     Document Type: Article

References (46)

1. Bell, S. M., Schreiner, C. M., Wert, S. E., Mucenski, M. L., Scott, W. J. and Whitsett, J. A. (2008). R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis. Development 135, 1049-1058.
2. Bogani, D., Warr, N., Elms, P., Davies, J., Tymowska-Lalanne, Z., Goldsworthy, M., Cox, R. D., Keays, D. A., Flint, J., Wilson, V. et al. (2004). New semidominant mutations that affect mouse development. Genesis 40, 109-117. (Pubitemid 39488507)
3. Brott, B. K. and Sokol, S. Y. (2002). Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins. Mol. Cell. Biol. 22, 6100-6110.
4. Caneparo, L., Huang, Y. L., Staudt, N., Tada, M., Ahrendt, R., Kazanskaya, O., Niehrs, C. and Houart, C. (2007). Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. Genes Dev. 21, 465-480.
5. Carter, M., Chen, X., Slowinska, B., Minnerath, S., Glickstein, S., Shi, L., Campagne, F., Weinstein, H. and Ross, M. E. (2005). Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6. Proc. Natl. Acad. Sci. USA 102, 12843-12848.
6. Fossat, N., Le Greneur, C., Beby, F., Vincent, S., Godement, P., Chatelain, G. and Lamonerie, T. (2007). A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors. BMC Dev. Biol. 7, 122.
7. Haegel, H., Larue, L., Ohsugi, M., Fedorov, L., Herrenknecht, K. and Kemler, R. (1995). Lack of beta-catenin affects mouse development at gastrulation. Development 121, 3529-3537. (Pubitemid 3000446)
8. He, X., Semenov, M., Tamai, K. and Zeng, X. (2004). LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 131, 1663-1677. (Pubitemid 38559836)
9. Huelsken, J., Vogel, R., Brinkmann, V., Erdmann, B., Birchmeier, C. and Birchmeier, W. (2000). Requirement for beta-catenin in anterior-posterior axis formation in mice. J. Cell Biol. 148, 567-578.
10. Inoue, T., Nakamura, S. and Osumi, N. (2000). Fate mapping of the mouse prosencephalic neural plate. Dev. Biol. 219, 373-383. (Pubitemid 30152612)
11. Junghans, D., Hack, I., Frotscher, M., Taylor, V. and Kemler, R. (2005). Beta-catenin-mediated cell-adhesion is vital for embryonic forebrain development. Dev. Dyn. 233, 528-539. (Pubitemid 40734052)
12. Kazanskaya, O., Glinka, A. and Niehrs, C. (2000). The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning. Development 127, 4981-4992. (Pubitemid 32000295)
13. Kelly, O. G., Pinson, K. I. and Skarnes, W. C. (2004). The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice. Development 131, 2803-2815.
14. Kemp, C. R., Willems, E., Wawrzak, D., Hendrickx, M., Agbor Agbor, T. and Leyns, L. (2007). Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling. Dev. Dyn. 236, 2011-2019. (Pubitemid 47076030)
15. Kim, K. A., Wagle, M., Tran, K., Zhan, X., Dixon, M. A., Liu, S., Gros, D., Korver, W., Yonkovich, S., Tomasevic, N. et al. (2008). R-Spondin family members regulate the Wnt pathway by a common mechanism. Mol. Biol. Cell 19, 2588-2596.
16. Kimura-Yoshida, C., Nakano, H., Okamura, D., Nakao, K., Yonemura, S., Belo, J. A., Aizawa, S., Matsui, Y. and Matsuo, I. (2005). Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm. Dev. Cell 9, 639-650. (Pubitemid 41555146)
17. Kokubu, C., Heinzmann, U., Kokubu, T., Sakai, N., Kubota, T., Kawai, M., Wahl, M. B., Galceran, J., Grosschedl, R., Ozono, K. et al. (2004). Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis. Development 131, 5469-5480. (Pubitemid 39562189)
18. Lagutin, O. V., Zhu, C. C., Kobayashi, D., Topczewski, J., Shimamura, K., Puelles, L., Russell, H. R., McKinnon, P. J., Solnica-Krezel, L. and Oliver, G. (2003). Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development. Genes Dev. 17, 368-379. (Pubitemid 36182196)
19. Lavado, A., Lagutin, O. V. and Oliver, G. (2008). Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon. Development 135, 441-450.
20. Lewis, S. L., Khoo, P. L., De Young, R. A., Bildsoe, H., Wakamiya, M., Behringer, R. R., Mukhopadhyay, M., Westphal, H. and Tam, P. P. (2007). Genetic interaction of Gsc and Dkk1 in head morphogenesis of the mouse. Mech. Dev. 124, 157-165. (Pubitemid 46136907)
21. Lewis, S. L., Khoo, P. L., De Young, R. A., Steiner, K., Wilcock, C., Mukhopadhyay, M., Westphal, H., Jamieson, R. V., Robb, L. and Tam, P. P. (2008). Dkk1 and Wnt3 interact to control head morphogenesis in the mouse. Development 135, 1791-1801.
22. Li, Y., Chen, J., Lu, W., McCormick, L. M., Wang, J. and Bu, G. (2005). Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding. J. Cell Sci. 118, 5305-5314. (Pubitemid 41819592)
23. Liu, P., Wakamiya, M., Shea, M. J., Albrecht, U., Behringer, R. R. and Bradley, A. (1999). Requirement for Wnt3 in vertebrate axis formation. Nat. Genet. 22, 361-365. (Pubitemid 29369527)
24. Logan, C. Y. and Nusse, R. (2004). The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20, 781-810. (Pubitemid 39488658)
25. Lu, C. C., Robertson, E. J. and Brennan, J. (2004). The mouse frizzled 8 receptor is expressed in anterior organizer tissues. Gene Expr. Patterns 4, 569-572. (Pubitemid 38992399)
26. MacDonald, B. T., Adamska, M. and Meisler, M. H. (2004). Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. Development 131, 2543-2552.
27. MacDonald, B. T., Tamai, K. and He, X. (2009). Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell 17, 9-26.
28. Mao, B., Wu, W., Li, Y., Hoppe, D., Stannek, P., Glinka, A. and Niehrs, C. (2001). LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411, 321-325. (Pubitemid 32467039)
29. Maretto, S., Cordenonsi, M., Dupont, S., Braghetta, P., Broccoli, V., Hassan, A. B., Volpin, D., Bressan, G. M. and Piccolo, S. (2003). Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc. Natl. Acad. Sci. USA 100, 3299-3304. (Pubitemid 36356577)
30. Mukhopadhyay, M., Shtrom, S., Rodriguez-Esteban, C., Chen, L., Tsukui, T., Gomer, L., Dorward, D. W., Glinka, A., Grinberg, A., Huang, S. P. et al. (2001). Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Dev. Cell 1, 423-434. (Pubitemid 33586091)
31. Niehrs, C. (2004). Regionally specific induction by the Spemann-Mangold organizer. Nat. Rev. Genet. 5, 425-434.
32. Nolan, P. M., Peters, J., Strivens, M., Rogers, D., Hagan, J., Spurr, N., Gray, I. C., Vizor, L., Brooker, D., Whitehill, E. et al. (2000). A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat. Genet. 25, 440-443. (Pubitemid 32983439)
33. Petersen, C. P. and Reddien, P. W. (2009). Wnt signaling and the polarity of the primary body axis. Cell 139, 1056-1068.
34. Pinson, K. I., Brennan, J., Monkley, S., Avery, B. J. and Skarnes, W. C. (2000). An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 407, 535-538.
35. Robb, L. and Tam, P. P. (2004). Gastrula organiser and embryonic patterning in the mouse. Semin. Cell Dev. Biol. 15, 543-554. (Pubitemid 38953951)
36. Rubenstein, J. L., Shimamura, K., Martinez, S. and Puelles, L. (1998). Regionalization of the prosencephalic neural plate. Annu. Rev. Neurosci. 21, 445-477. (Pubitemid 28150670)
37. Schneider, S. Q., Finnerty, J. R. and Martindale, M. Q. (2003). Protein evolution: structure-function relationships of the oncogene beta-catenin in the evolution of multicellular animals. J. Exp. Zool. B Mol. Dev. Evol. 295, 25-44.
38. Semenov, M. V., Tamai, K., Brott, B. K., Kuhl, M., Sokol, S. and He, X. (2001). Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr. Biol. 11, 951-961. (Pubitemid 32589186)
39. Shinya, M., Eschbach, C., Clark, M., Lehrach, H. and Furutani-Seiki, M. (2000). Zebrafish Dkk1, induced by the pre-MBT Wnt signaling, is secreted from the prechordal plate and patterns the anterior neural plate. Mech. Dev. 98, 3-17.
40. Simeone, A., Gulisano, M., Acampora, D., Stornaiuolo, A., Rambaldi, M. and Boncinelli, E. (1992). Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 11, 2541-2550.
41. Stadeli, R., Hoffmans, R. and Basler, K. (2006). Transcription under the control of nuclear Arm/beta-catenin. Curr. Biol. 16, R378-R385.
42. Tam, P. P. (1989). Regionalisation of the mouse embryonic ectoderm: allocation of prospective ectodermal tissues during gastrulation. Development 107, 55-67.
43. Willert, K. and Jones, K. A. (2006). Wnt signaling: is the party in the nucleus? Genes Dev. 20, 1394-1404.
44. Yamaguchi, T. P., Bradley, A., McMahon, A. P. and Jones, S. (1999). A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 126, 1211-1223. (Pubitemid 29182117)
45. Yao, J. and Kessler, D. S. (2001). Goosecoid promotes head organizer activity by direct repression of Xwnt8 in Spemann's organizer. Development 128, 2975-2987. (Pubitemid 32771629)
46. Yap, A. S., Brieher, W. M. and Gumbiner, B. M. (1997). Molecular and functional analysis of cadherin-based adherens junctions. Annu. Rev. Cell Dev. Biol. 13, 119-146.