-
2
-
-
34247527730
-
Hypoxia inducible factors, Stem cells, and Cancer
-
[CrossRef] [PubMed]
-
Keith, B.; Simon, MC. Hypoxia inducible factors, Stem cells, and Cancer. Cell 2007, 129, 465-472. [CrossRef] [PubMed]
-
(2007)
Cell
, vol.129
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
3
-
-
84655161946
-
HIF1α and HIF2α: Sibling rivalry in hypoxic tumor growth and progression
-
[CrossRef] [PubMed]
-
Keith, B.; Johnson, R.S.; Simon, M.C. HIF1α and HIF2α: Sibling rivalry in hypoxic tumor growth and progression. Nat. Rev. Cancer 2012, 12, 9-22. [CrossRef] [PubMed]
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 9-22
-
-
Keith, B.1
Johnson, R.S.2
Simon, M.C.3
-
4
-
-
84893077858
-
Transcriptional regulation by hypoxia inducible factors
-
[CrossRef] [PubMed]
-
Dengler, V.L.; Galbraith, M.; Espinosa, J.M. Transcriptional regulation by hypoxia inducible factors. Crit. Rev. Biochem. Mol. Biol. 2014, 49, 1-15. [CrossRef] [PubMed]
-
(2014)
Crit. Rev. Biochem. Mol. Biol.
, vol.49
, pp. 1-15
-
-
Dengler, V.L.1
Galbraith, M.2
Espinosa, J.M.3
-
5
-
-
44349157832
-
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
-
[CrossRef] [PubMed]
-
Dewhirst, M.W.; Cao, Y.; Moeller, B. Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response. Nat. Rev. Cancer 2008, 8, 425-437. [CrossRef] [PubMed]
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 425-437
-
-
Dewhirst, M.W.1
Cao, Y.2
Moeller, B.3
-
6
-
-
84897990135
-
Tumor stroma: A complexity dictated by the hypoxic tumor microenvironment
-
[CrossRef] [PubMed]
-
Casazza, A.; di Conza, G.; Wenes, M.; Finisguerra, V.; Deschomaeker, S.; Mazzone, M. Tumor stroma: A complexity dictated by the hypoxic tumor microenvironment. Oncogene 2014, 33, 1743-1754. [CrossRef] [PubMed]
-
(2014)
Oncogene
, vol.33
, pp. 1743-1754
-
-
Casazza, A.1
di Conza, G.2
Wenes, M.3
Finisguerra, V.4
Deschomaeker, S.5
Mazzone, M.6
-
7
-
-
54549089738
-
Hypoxia signaling through mTOR and the unfolded protein response in cancer
-
[CrossRef] [PubMed]
-
Wouters, B.G.; Koritzinsky, M. Hypoxia signaling through mTOR and the unfolded protein response in cancer. Nat. Rev. Cancer 2008, 8, 851-864. [CrossRef] [PubMed]
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 851-864
-
-
Wouters, B.G.1
Koritzinsky, M.2
-
8
-
-
44749090905
-
Sp1: Emerging roles-beyond constitutive activation of TATA-less housekeeping genes
-
[CrossRef] [PubMed]
-
Wierstra, I. Sp1: Emerging roles-beyond constitutive activation of TATA-less housekeeping genes. Biochem. Biophys. Res. Commun. 2008, 372, 1-13. [CrossRef] [PubMed]
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.372
, pp. 1-13
-
-
Wierstra, I.1
-
9
-
-
84926081071
-
Sp1 and the "hallmarks of cancer"
-
[CrossRef] [PubMed]
-
Beishline, K.; Azizkhan-Clifford, J. Sp1 and the "hallmarks of cancer". FEBS J. 2015, 282, 224-258. [CrossRef] [PubMed]
-
(2015)
FEBS J.
, vol.282
, pp. 224-258
-
-
Beishline, K.1
Azizkhan-Clifford, J.2
-
10
-
-
0037096732
-
Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene
-
[PubMed]
-
Comerford, K.M.; Wallace, T.J.; Karhausen, J.; Louis, N.A.; Montalto, M.C.; Colgan, S.P. Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. Cancer Res. 2002, 62, 3387-3394. [PubMed]
-
(2002)
Cancer Res.
, vol.62
, pp. 3387-3394
-
-
Comerford, K.M.1
Wallace, T.J.2
Karhausen, J.3
Louis, N.A.4
Montalto, M.C.5
Colgan, S.P.6
-
11
-
-
2442502748
-
Hypoxia-induced activation of the retinoic acid receptor-related orphan receptor a4 gene by an interaction between hypoxia-inducible factor-1 and Sp1
-
[CrossRef] [PubMed]
-
Miki, N.; Ikuta, M.; Matsui, T. hypoxia-induced activation of the retinoic acid receptor-related orphan receptor a4 gene by an interaction between hypoxia-inducible factor-1 and Sp1. J. Biol. Chem. 2004, 279, 15025-15031. [CrossRef] [PubMed]
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 15025-15031
-
-
Miki, N.1
Ikuta, M.2
Matsui, T.3
-
12
-
-
84865333867
-
Hypoxia upregulates CD147 through a combined effect of HIF-1α and Sp1 to promote glycolysis and tumor progression in epitherial solid tumors
-
[CrossRef] [PubMed]
-
Ke, X.; Fei, F.; Chen, Y.; Xu, L.; Zhang, Z.; Huang, Q.; Zhang, H.; Yang, H.; Chen, Z.; Xing, J. Hypoxia upregulates CD147 through a combined effect of HIF-1α and Sp1 to promote glycolysis and tumor progression in epitherial solid tumors. Carcinogenesis 2012, 33, 1598-1607. [CrossRef] [PubMed]
-
(2012)
Carcinogenesis
, vol.33
, pp. 1598-1607
-
-
Ke, X.1
Fei, F.2
Chen, Y.3
Xu, L.4
Zhang, Z.5
Huang, Q.6
Zhang, H.7
Yang, H.8
Chen, Z.9
Xing, J.10
-
13
-
-
0037374179
-
Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. Identification of a novel type of hypoxia-responsive enhancer
-
[PubMed]
-
Kaluz, S.; Kaluzova, M.; Stanbridge, E.J. Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. Identification of a novel type of hypoxia-responsive enhancer. Cancer Res. 2003, 63, 917-922. [PubMed]
-
(2003)
Cancer Res.
, vol.63
, pp. 917-922
-
-
Kaluz, S.1
Kaluzova, M.2
Stanbridge, E.J.3
-
15
-
-
79954428147
-
Up-regulation of glyceraldehydes-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells
-
[CrossRef] [PubMed]
-
Higashimura, Y.; Nakajima, Y.; Yamaji, R.; Harada, N.; Shibasaki, F.; Nakano, Y.; Inui, H. Up-regulation of glyceraldehydes-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells. Arch. Biochem. Biophys. 2011, 509, 1-8. [CrossRef] [PubMed]
-
(2011)
Arch. Biochem. Biophys.
, vol.509
, pp. 1-8
-
-
Higashimura, Y.1
Nakajima, Y.2
Yamaji, R.3
Harada, N.4
Shibasaki, F.5
Nakano, Y.6
Inui, H.7
-
16
-
-
49649100035
-
Insulin-dependent leptin expression in breast cancer cells
-
[CrossRef] [PubMed]
-
Bartella, V.; Cascio, S.; Fiorio, E.; Auriemma, A.; Russo, A.; Surmacz, E. Insulin-dependent leptin expression in breast cancer cells. Cancer Res. 2008, 68, 4919-4927. [CrossRef] [PubMed]
-
(2008)
Cancer Res.
, vol.68
, pp. 4919-4927
-
-
Bartella, V.1
Cascio, S.2
Fiorio, E.3
Auriemma, A.4
Russo, A.5
Surmacz, E.6
-
17
-
-
84882379413
-
Transcription factors Sp1 and HIF2α mediate induction of the copper-transporting ATPase (Atp7a) gene in intestinal epitherial cells during hypoxia
-
[CrossRef] [PubMed]
-
Xie, L.; Collins, J.F. Transcription factors Sp1 and HIF2α mediate induction of the copper-transporting ATPase (Atp7a) gene in intestinal epitherial cells during hypoxia. J. Biol. Chem. 2013, 288, 23943-23952. [CrossRef] [PubMed]
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 23943-23952
-
-
Xie, L.1
Collins, J.F.2
-
18
-
-
4143078131
-
The PAI-1 gene as a direct target of endotherial PAS domain protein-1 in adenocarcinoma A549 cells
-
[CrossRef] [PubMed]
-
Sato, M.; Tanaka, T.; Maemura, K.; Ucjyama, T.; Sato, H.; Maeno, T.; Suga, T.; Iso, T.; Ohyama, Y.; Arai, M.; et al. The PAI-1 gene as a direct target of endotherial PAS domain protein-1 in adenocarcinoma A549 cells. Am. J. Respir. Cell Mol. Biol. 2004, 31, 209-215. [CrossRef] [PubMed]
-
(2004)
Am. J. Respir. Cell Mol. Biol.
, vol.31
, pp. 209-215
-
-
Sato, M.1
Tanaka, T.2
Maemura, K.3
Ucjyama, T.4
Sato, H.5
Maeno, T.6
Suga, T.7
Iso, T.8
Ohyama, Y.9
Arai, M.10
-
19
-
-
13944252559
-
Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2α in von Hippel-Lindau renal cell carcinoma
-
[CrossRef] [PubMed]
-
Petrella, B.L.; Lohi, J.; Brinckerhoff, C.E. Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2α in von Hippel-Lindau renal cell carcinoma. Oncogene 2005, 24, 1043-1052. [CrossRef] [PubMed]
-
(2005)
Oncogene
, vol.24
, pp. 1043-1052
-
-
Petrella, B.L.1
Lohi, J.2
Brinckerhoff, C.E.3
-
20
-
-
80052226694
-
Translational and transcriptional control of Sp1 against ischemia through a hydrogen peroxide-activated internal ribosomal entry site pathway
-
[CrossRef] [PubMed]
-
Yeh, S.H.; Yang, W.B.; Gean, P.W.; Hsu, C.Y.; Tseng, J.T.; Su, T.P.; Chang, W.C.; Hung, J.J. Translational and transcriptional control of Sp1 against ischemia through a hydrogen peroxide-activated internal ribosomal entry site pathway. Nucleic Acids Res. 2011, 39, 5412-5423. [CrossRef] [PubMed]
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 5412-5423
-
-
Yeh, S.H.1
Yang, W.B.2
Gean, P.W.3
Hsu, C.Y.4
Tseng, J.T.5
Su, T.P.6
Chang, W.C.7
Hung, J.J.8
-
21
-
-
84870389718
-
Transcriptional regulation of specific protein 1 (SP1) by hypoxia-inducible factor 1 alpha (HIF-1α) leads to PRNP expression and neuroprotection from toxic prion peptide
-
[CrossRef] [PubMed]
-
Jeong, J.-K.; Park, S.-Y. Transcriptional regulation of specific protein 1 (SP1) by hypoxia-inducible factor 1 alpha (HIF-1α) leads to PRNP expression and neuroprotection from toxic prion peptide. Biochem. Biophys. Res. Commun. 2012, 429, 93-98. [CrossRef] [PubMed]
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.429
, pp. 93-98
-
-
Jeong, J.-K.1
Park, S.-Y.2
-
22
-
-
70350456139
-
Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia
-
[CrossRef] [PubMed]
-
Szalad, A.; Katakowski, M.; Zheng, X.; Jiang, F.; Chopp, M. Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia. J. Exp. Clin. Cancer Res. 2009, 28, 129. [CrossRef] [PubMed]
-
(2009)
J. Exp. Clin. Cancer Res.
, vol.28
, pp. 129
-
-
Szalad, A.1
Katakowski, M.2
Zheng, X.3
Jiang, F.4
Chopp, M.5
-
23
-
-
53849121584
-
Hypoxia upregulates expression of human endosialin gene via hypoxia-inducible factor 2
-
[CrossRef] [PubMed]
-
Ohradanova, A.; Gradin, K.; Barathova, M.; Zatovicova, M.; Holotnakova, T.; Kopacek, J.; Parkkila, S.; Poellinger, L.; Pastorekova, S.; Pastorek, J. Hypoxia upregulates expression of human endosialin gene via hypoxia-inducible factor 2. Br. J. Cancer 2008, 99, 1348-1356. [CrossRef] [PubMed]
-
(2008)
Br. J. Cancer
, vol.99
, pp. 1348-1356
-
-
Ohradanova, A.1
Gradin, K.2
Barathova, M.3
Zatovicova, M.4
Holotnakova, T.5
Kopacek, J.6
Parkkila, S.7
Poellinger, L.8
Pastorekova, S.9
Pastorek, J.10
-
24
-
-
84942133244
-
Anti-endosialin antibody-drug conjugate: Potential in sarcoma and other malignancies
-
[CrossRef] [PubMed]
-
Rouleau, C.; Gianolio, D.A.; Smale, R.; Roth, S.D.; Krumbholz, R.; Harper, J.; Munroe, K.J.; Green, T.L.; Horten, B.C.; Schmid, S.M.; et al. Anti-endosialin antibody-drug conjugate: Potential in sarcoma and other malignancies. Mol. Cancer Ther. 2015, 14, OF1-OF9. [CrossRef] [PubMed]
-
(2015)
Mol. Cancer Ther.
, vol.14
, pp. OF1-OF9
-
-
Rouleau, C.1
Gianolio, D.A.2
Smale, R.3
Roth, S.D.4
Krumbholz, R.5
Harper, J.6
Munroe, K.J.7
Green, T.L.8
Horten, B.C.9
Schmid, S.M.10
-
25
-
-
84857782590
-
Sequential activation of hypoxia-inducible factor 1 and specificity protein 1 is required for hypoxia-induced transcriptional stimulation of Abcc8
-
[CrossRef] [PubMed]
-
Woo, S.K.; Kwon, M.S.; Geng, Z.; Chen, Z.; Ivanov, A.; Bhatta, S.; Gerzanich, V.; Simard, J.M. Sequential activation of hypoxia-inducible factor 1 and specificity protein 1 is required for hypoxia-induced transcriptional stimulation of Abcc8. J. Cereb. Blood Flow Metab. 2012, 32, 525-536. [CrossRef] [PubMed]
-
(2012)
J. Cereb. Blood Flow Metab.
, vol.32
, pp. 525-536
-
-
Woo, S.K.1
Kwon, M.S.2
Geng, Z.3
Chen, Z.4
Ivanov, A.5
Bhatta, S.6
Gerzanich, V.7
Simard, J.M.8
-
26
-
-
80054763120
-
Opposite effects of HIF-1α and HIF-2α on the regulation of IL-8 in endothelial cells
-
[CrossRef] [PubMed]
-
Florczyk, U.; Czauderna, S.; Stachurska, A.; Tertil, M.; Nowak, W.; Kozakowska, M.; Poellinger, L.; Jozkowicz, A.; Loboda, A.; Dulak, J. Opposite effects of HIF-1α and HIF-2α on the regulation of IL-8 in endothelial cells. Free Radic. Biol. Med. 2011, 51, 1882-1892. [CrossRef] [PubMed]
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 1882-1892
-
-
Florczyk, U.1
Czauderna, S.2
Stachurska, A.3
Tertil, M.4
Nowak, W.5
Kozakowska, M.6
Poellinger, L.7
Jozkowicz, A.8
Loboda, A.9
Dulak, J.10
-
27
-
-
0032476059
-
Hypoxia regulates β-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element
-
[CrossRef] [PubMed]
-
Discher, D.J.; Bishopric, N.H.; Wu, X.; Peterson, C.A.; Webster, K.A. Hypoxia regulates β-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element. J. Biol. Chem. 1998, 273, 26087-26093. [CrossRef] [PubMed]
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26087-26093
-
-
Discher, D.J.1
Bishopric, N.H.2
Wu, X.3
Peterson, C.A.4
Webster, K.A.5
-
28
-
-
0035884402
-
Central role of p53 on regulation of vascular permeability factor/vascular endothelial factor (VPF/VEGF) expression in mammary carcinoma
-
[PubMed]
-
Pal, S.; Datta, K.; Mukhopadhyay, D. Central role of p53 on regulation of vascular permeability factor/vascular endothelial factor (VPF/VEGF) expression in mammary carcinoma. Cancer Res. 2001, 61, 6952-6957. [PubMed]
-
(2001)
Cancer Res.
, vol.61
, pp. 6952-6957
-
-
Pal, S.1
Datta, K.2
Mukhopadhyay, D.3
-
29
-
-
79959968571
-
Molecular mechanism of HIF-1-independent VEGF expression in a hepatocellular carcinoma cell line
-
[PubMed]
-
Choi, S.B.; Park, J.B.; Song, T.-J.; Choi, S.Y. Molecular mechanism of HIF-1-independent VEGF expression in a hepatocellular carcinoma cell line. Int. J. Mol. Med. 2011, 28, 449-454. [PubMed]
-
(2011)
Int. J. Mol. Med.
, vol.28
, pp. 449-454
-
-
Choi, S.B.1
Park, J.B.2
Song, T.-J.3
Choi, S.Y.4
-
30
-
-
33749472340
-
Nelfinavir down-regulates hypoxia-inducible factor 1α and VEGF expression and increases tumor oxygenation: Implications for radiotherapy
-
[CrossRef] [PubMed]
-
Pore, N.; Gupta, A.K.; Cerniglia, G.J.; Jiang, Z.; Bernhard, E.J.; Evans, S.M.; Koch, C.J.; Hahn, S.M.; Maity, A. Nelfinavir down-regulates hypoxia-inducible factor 1α and VEGF expression and increases tumor oxygenation: Implications for radiotherapy. Cancer Res. 2006, 66, 9252-9259. [CrossRef] [PubMed]
-
(2006)
Cancer Res.
, vol.66
, pp. 9252-9259
-
-
Pore, N.1
Gupta, A.K.2
Cerniglia, G.J.3
Jiang, Z.4
Bernhard, E.J.5
Evans, S.M.6
Koch, C.J.7
Hahn, S.M.8
Maity, A.9
-
31
-
-
78650236478
-
Modulation of hypoxia-inducible factor-1α expression by mitochondrial NADP+-dependent isocitrate dehydrogenase
-
[CrossRef] [PubMed]
-
Kim, S.Y.; Park, J.-W. Modulation of hypoxia-inducible factor-1α expression by mitochondrial NADP+-dependent isocitrate dehydrogenase. Biochimie 2010, 92, 1908-1913. [CrossRef] [PubMed]
-
(2010)
Biochimie
, vol.92
, pp. 1908-1913
-
-
Kim, S.Y.1
Park, J.-W.2
-
32
-
-
33744948425
-
Hypoxia regulates cross-talk between Syk and Lck leading to breast cancer progression and angiogenesis
-
[CrossRef] [PubMed]
-
Chakraborty, G.; Rangaswami, H.; Jain, S.; Kundu, G.C. Hypoxia regulates cross-talk between Syk and Lck leading to breast cancer progression and angiogenesis. J. Biol. Chem. 2006, 281, 11322-11331. [CrossRef] [PubMed]
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 11322-11331
-
-
Chakraborty, G.1
Rangaswami, H.2
Jain, S.3
Kundu, G.C.4
-
33
-
-
0037103797
-
Hypoxia/reoxygenation induction of monocyte chemoattractant protein-1 in melanoma cells: Involvement of nuclear factor-kB, stimulatory protein-1 transcription factors and mitogen-activated protein kinase pathways
-
[CrossRef] [PubMed]
-
Kunz, M.; Bloss, G.; Gillitzer, R.; Gross, G.; Goebeller, M.; Rapp, U.R.; Ludwig, S. Hypoxia/reoxygenation induction of monocyte chemoattractant protein-1 in melanoma cells: Involvement of nuclear factor-kB, stimulatory protein-1 transcription factors and mitogen-activated protein kinase pathways. Biochem. J. 2002, 366, 299-306. [CrossRef] [PubMed]
-
(2002)
Biochem. J.
, vol.366
, pp. 299-306
-
-
Kunz, M.1
Bloss, G.2
Gillitzer, R.3
Gross, G.4
Goebeller, M.5
Rapp, U.R.6
Ludwig, S.7
-
34
-
-
1342325424
-
Bcl-2 induction of urokinase plasminogen activator receptor expression in human cancer cells through Sp1 activation
-
[CrossRef] [PubMed]
-
Trisciuoglio, D.; Iervolino, A.; Candiloro, A.; Fibbi, G.; Fanciulli, M.; Zangemeister-Wittke, U.; Zupi, G.; Del Bufalo, D. Bcl-2 induction of urokinase plasminogen activator receptor expression in human cancer cells through Sp1 activation. J. Biol. Chem. 2004, 279, 6737-6745. [CrossRef] [PubMed]
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 6737-6745
-
-
Trisciuoglio, D.1
Iervolino, A.2
Candiloro, A.3
Fibbi, G.4
Fanciulli, M.5
Zangemeister-Wittke, U.6
Zupi, G.7
Del Bufalo, D.8
-
35
-
-
48849107453
-
Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions
-
[CrossRef] [PubMed]
-
Kato, A.; Endo, T.; Abiko, S.; Ariga, H.; Matsumoto, K. Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions. Exp. Cell Res. 2008, 314, 2661-2673. [CrossRef] [PubMed]
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 2661-2673
-
-
Kato, A.1
Endo, T.2
Abiko, S.3
Ariga, H.4
Matsumoto, K.5
-
36
-
-
84883303719
-
PIASy mediates hypoxia-induced SIRT1 transcriptionalrepression and epithelial-to-mesenchymal transition in ovarian cancer cells
-
[CrossRef] [PubMed]
-
Sun, L.; Li, H.; Chen, J.; Iwasaki, Y.; Kubota, T.; Matsuoka, M.; Shen, A.; Chen, Q.; Xu, Y. PIASy mediates hypoxia-induced SIRT1 transcriptionalrepression and epithelial-to-mesenchymal transition in ovarian cancer cells. J. Cell Sci. 2013, 126, 3939-3947. [CrossRef] [PubMed]
-
(2013)
J. Cell Sci.
, vol.126
, pp. 3939-3947
-
-
Sun, L.1
Li, H.2
Chen, J.3
Iwasaki, Y.4
Kubota, T.5
Matsuoka, M.6
Shen, A.7
Chen, Q.8
Xu, Y.9
-
37
-
-
84883046166
-
A SUMOylation-dependent pathway regulates SIRT1 transcription and lung cancer metastasis
-
[CrossRef] [PubMed]
-
Sun, L.; Li, H.; Chen, J.; Dehennaut, V.; Zhao, Y.; Yang, Y.; Iwasaki, Y.; Kahn-Perles, B.; Leprince, D.; Chen, Q.; et al. A SUMOylation-dependent pathway regulates SIRT1 transcription and lung cancer metastasis. J. Natl. Cancer Inst. 2013, 105, 887-898. [CrossRef] [PubMed]
-
(2013)
J. Natl. Cancer Inst.
, vol.105
, pp. 887-898
-
-
Sun, L.1
Li, H.2
Chen, J.3
Dehennaut, V.4
Zhao, Y.5
Yang, Y.6
Iwasaki, Y.7
Kahn-Perles, B.8
Leprince, D.9
Chen, Q.10
-
38
-
-
79954550386
-
HIF-1α depletion results in SP1-mediated cell cycle disruption and alters the cellular response to chemotherapeutic drugs
-
[CrossRef] [PubMed]
-
Culver, C.; Melvin, A.; Mudie, S.; Rocha, S. HIF-1α depletion results in SP1-mediated cell cycle disruption and alters the cellular response to chemotherapeutic drugs. Cell Cycle 2011, 10, 1249-1260. [CrossRef] [PubMed]
-
(2011)
Cell Cycle
, vol.10
, pp. 1249-1260
-
-
Culver, C.1
Melvin, A.2
Mudie, S.3
Rocha, S.4
-
39
-
-
0025891698
-
DNA looping between sites for transcriptional activation: Self-association of DNA-bound Sp1
-
[CrossRef] [PubMed]
-
Su, W.; Jackson, S.; Tijan, R.; Echols, H. DNA looping between sites for transcriptional activation: Self-association of DNA-bound Sp1. Genes Dev. 1991, 5, 820-826. [CrossRef] [PubMed]
-
(1991)
Genes Dev.
, vol.5
, pp. 820-826
-
-
Su, W.1
Jackson, S.2
Tijan, R.3
Echols, H.4
-
40
-
-
84887437551
-
Pituitary adenylate cyclase-activating polypeptide type 1receptor (PAC1) gene is suppressed by transglutaminase 2 activation
-
[CrossRef] [PubMed]
-
Miura, A.; Kambe, Y.; Inoue, K.; Tatsukawa, H.; Kurihara, T.; Griffin, M.; Kojima, S.; Miyata, A. Pituitary adenylate cyclase-activating polypeptide type 1receptor (PAC1) gene is suppressed by transglutaminase 2 activation. J. Biol. Chem. 2013, 288, 32720-32730. [CrossRef] [PubMed]
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 32720-32730
-
-
Miura, A.1
Kambe, Y.2
Inoue, K.3
Tatsukawa, H.4
Kurihara, T.5
Griffin, M.6
Kojima, S.7
Miyata, A.8
-
41
-
-
33750286014
-
Activation of cancer cell migration and invasion by ectopic expression of coagulation factor VII
-
[CrossRef] [PubMed]
-
Koizume, S.; Jin, M.-S.; Miyagi, E.; Hirahara, F.; Nakamura, Y.; Piao, J.-H.; Asai, A.; Yoshida, A.; Tsuchiya, E.; Ruf, W.; et al. Activation of cancer cell migration and invasion by ectopic expression of coagulation factor VII. Cancer Res. 2006, 66, 9453-9460. [CrossRef] [PubMed]
-
(2006)
Cancer Res.
, vol.66
, pp. 9453-9460
-
-
Koizume, S.1
Jin, M.-S.2
Miyagi, E.3
Hirahara, F.4
Nakamura, Y.5
Piao, J.-H.6
Asai, A.7
Yoshida, A.8
Tsuchiya, E.9
Ruf, W.10
-
42
-
-
77950352065
-
Hypoxia-inducible factor-1a regulates the expression of nucleotide excision repair proteins in keratinocytes
-
[CrossRef] [PubMed]
-
Rezvani, H.R.; Mahfouf,W.; Ali, N.; Chemin, C.; Ged, C.; Kim, A.L.; de Verneuil, H.; Taieb, A.; Bickers, D.R.; Mazurier, F. Hypoxia-inducible factor-1a regulates the expression of nucleotide excision repair proteins in keratinocytes. Nucleic Acids Res. 2010, 38, 797-809. [CrossRef] [PubMed]
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 797-809
-
-
Rezvani, H.R.1
Mahfouf, W.2
Ali, N.3
Chemin, C.4
Ged, C.5
Kim, A.L.6
de Verneuil, H.7
Taieb, A.8
Bickers, D.R.9
Mazurier, F.10
-
43
-
-
35148883007
-
Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter
-
[CrossRef] [PubMed]
-
Zhang, P.; Tchou-Wong, K.M.; Costa, M. Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter. Cancer Res. 2007, 67, 9125-9133. [CrossRef] [PubMed]
-
(2007)
Cancer Res.
, vol.67
, pp. 9125-9133
-
-
Zhang, P.1
Tchou-Wong, K.M.2
Costa, M.3
-
44
-
-
85042572817
-
Suppressing the TF-fVII pathway at the gene expression level: A strategy to inhibit aberrant signaling cascades associated with cancer cells
-
Koizume, S.; Miyagi, Y. Suppressing the TF-fVII pathway at the gene expression level: A strategy to inhibit aberrant signaling cascades associated with cancer cells. Cancer Cell Microenviron. 2015, 2, e734.
-
(2015)
Cancer Cell Microenviron.
, vol.2
-
-
Koizume, S.1
Miyagi, Y.2
-
45
-
-
0033591346
-
Hypoxia-associated induction of early growth response-1 gene expression
-
[CrossRef] [PubMed]
-
Yan, S.-F.; Lu, J.; Zou, Y.S.; Soh-Won, J.; Cohen, D.M.; Buttrick, P.M.; Cooper, D.R.; Steinberg, S.F.; Mackman, N.; Pinsky, D.J.; et al. Hypoxia-associated induction of early growth response-1 gene expression. J. Biol. Chem. 1999, 274, 15030-15040. [CrossRef] [PubMed]
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15030-15040
-
-
Yan, S.-F.1
Lu, J.2
Zou, Y.S.3
Soh-Won, J.4
Cohen, D.M.5
Buttrick, P.M.6
Cooper, D.R.7
Steinberg, S.F.8
McKman, N.9
Pinsky, D.J.10
-
46
-
-
15244344206
-
HIF-1α induces genetic instability by transcriptionally downregulating MutSα expression
-
[CrossRef] [PubMed]
-
Koshiji, M.; To, K.K.-W.; Hammer, S.; Kumamoto, K.; Harris, A.L.; Modrich, P.; Huang, L.E. HIF-1α induces genetic instability by transcriptionally downregulating MutSα expression. Mol. Cell 2005, 17, 793-803. [CrossRef] [PubMed]
-
(2005)
Mol. Cell
, vol.17
, pp. 793-803
-
-
Koshiji, M.1
To, K.K.-W.2
Hammer, S.3
Kumamoto, K.4
Harris, A.L.5
Modrich, P.6
Huang, L.E.7
-
47
-
-
33750202279
-
The phosphorylation status of PAS-B distinguishes HIF-1α from HIF-2α in NBS1 repression
-
[CrossRef] [PubMed]
-
To, K.K.-W.; Sedelnikova, O.A.; Samons, M.; Bonner, W.M.; Huang, L.E. The phosphorylation status of PAS-B distinguishes HIF-1α from HIF-2α in NBS1 repression. EMBO J. 2006, 25, 4784-4794. [CrossRef] [PubMed]
-
(2006)
EMBO J.
, vol.25
, pp. 4784-4794
-
-
To, K.K.-W.1
Sedelnikova, O.A.2
Samons, M.3
Bonner, W.M.4
Huang, L.E.5
-
48
-
-
34047156190
-
HIF-2α promotes hypoxic cell proliferation by enhancing c-Myc transcriptional activity
-
[CrossRef] [PubMed]
-
Gordan, J.D.; Bertout, J.A.; Hu, C-J.; Diehl, J.A.; Simon, M.C. HIF-2α promotes hypoxic cell proliferation by enhancing c-Myc transcriptional activity. Cancer Cell 2007, 11, 335-347. [CrossRef] [PubMed]
-
(2007)
Cancer Cell
, vol.11
, pp. 335-347
-
-
Gordan, J.D.1
Bertout, J.A.2
Hu, C.-J.3
Diehl, J.A.4
Simon, M.C.5
-
49
-
-
84863223765
-
HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells
-
[CrossRef] [PubMed]
-
Koizume, S.; Ito, S.; Miyagi, E.; Hirahara, F.; Nakamura, Y.; Sakuma, Y.; Osaka, H.; Takano, Y.; Ruf, W.; Miyagi, Y. HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells. Nucleic Acids Res. 2012, 40, 5389-5401. [CrossRef] [PubMed]
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 5389-5401
-
-
Koizume, S.1
Ito, S.2
Miyagi, E.3
Hirahara, F.4
Nakamura, Y.5
Sakuma, Y.6
Osaka, H.7
Takano, Y.8
Ruf, W.9
Miyagi, Y.10
-
50
-
-
84927555901
-
Lipid starvation and hypoxia synergistically activates ICAM1 and multiple genes in an Sp1-dependent manner to promote the growth of ovarian cancer
-
[CrossRef] [PubMed]
-
Koizume, S.; Ito, S.; Nakamura, Y.; Yoshihara, M.; Furuya, M.; Yamada, R.; Miyagi, E.; Hirahara, F.; Takano, Y.; Miyagi, Y. Lipid starvation and hypoxia synergistically activates ICAM1 and multiple genes in an Sp1-dependent manner to promote the growth of ovarian cancer. Mol. Cancer 2015, 14, 77. [CrossRef] [PubMed]
-
(2015)
Mol. Cancer
, vol.14
, pp. 77
-
-
Koizume, S.1
Ito, S.2
Nakamura, Y.3
Yoshihara, M.4
Furuya, M.5
Yamada, R.6
Miyagi, E.7
Hirahara, F.8
Takano, Y.9
Miyagi, Y.10
-
51
-
-
84908333251
-
EPAS-1 mediates SP-1-dependent FBI-1 expression and regulates tumor cell survival and proliferation
-
[CrossRef] [PubMed]
-
Wang, X.; Cao, P.; Li, Z.;Wu, D.;Wang, X.; Liang, G. EPAS-1 mediates SP-1-dependent FBI-1 expression and regulates tumor cell survival and proliferation. Int. J. Mol. Sci. 2014, 15, 15689-15699. [CrossRef] [PubMed]
-
(2014)
Int. J. Mol. Sci.
, vol.15
, pp. 15689-15699
-
-
Wang, X.1
Cao, P.2
Li, Z.3
Wu, D.4
Wang, X.5
Liang, G.6
-
52
-
-
84930938538
-
Anti-apoptotic genes are synergistically activated in OVSAYO cells cultured under conditions of serum starvation and hypoxia
-
[CrossRef] [PubMed]
-
Koizume, S.; Miyagi, Y. Anti-apoptotic genes are synergistically activated in OVSAYO cells cultured under conditions of serum starvation and hypoxia. Genom. Data 2015, 5, 129-131. [CrossRef] [PubMed]
-
(2015)
Genom. Data
, vol.5
, pp. 129-131
-
-
Koizume, S.1
Miyagi, Y.2
-
53
-
-
70450278715
-
Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1α gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway
-
[CrossRef] [PubMed]
-
Koshikawa, N.; Hayashi, J.; Nakagawara, A.; Takenaga, K. Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1α gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway. J. Biol. Chem. 2009, 48, 33185-33194. [CrossRef] [PubMed]
-
(2009)
J. Biol. Chem.
, vol.48
, pp. 33185-33194
-
-
Koshikawa, N.1
Hayashi, J.2
Nakagawara, A.3
Takenaga, K.4
-
54
-
-
84857436181
-
Roles of Sp1 transcription factors in the regulation of cancer cell metabolism
-
[CrossRef] [PubMed]
-
Archer, M.C. Roles of Sp1 transcription factors in the regulation of cancer cell metabolism. Genes Cancer 2011, 2, 712-719. [CrossRef] [PubMed]
-
(2011)
Genes Cancer
, vol.2
, pp. 712-719
-
-
Archer, M.C.1
-
55
-
-
82355164170
-
Inhibition of glycolytic enzymes mediated by pharmacologically activated p53
-
[CrossRef] [PubMed]
-
Zawacka-Pankau, J.; Grinkevich, V.V.; Hunten, S.; Nikulenkov, F.; Gluch, A.; Li, H.; Enge, M.; Kel, A.; Selivanova, G. Inhibition of glycolytic enzymes mediated by pharmacologically activated p53. J. Biol. Chem. 2011, 48, 41600-41615. [CrossRef] [PubMed]
-
(2011)
J. Biol. Chem.
, vol.48
, pp. 41600-41615
-
-
Zawacka-Pankau, J.1
Grinkevich, V.V.2
Hunten, S.3
Nikulenkov, F.4
Gluch, A.5
Li, H.6
Enge, M.7
Kel, A.8
Selivanova, G.9
-
56
-
-
35448982386
-
Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions
-
[CrossRef] [PubMed]
-
Vlaminck, B.; Toffoli, S.; Ghislain, B.; Demazy, C.; Raes, M.; Michiels, C. Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions. FEBS J. 2007, 274, 5533-5542. [CrossRef] [PubMed]
-
(2007)
FEBS J.
, vol.274
, pp. 5533-5542
-
-
Vlaminck, B.1
Toffoli, S.2
Ghislain, B.3
Demazy, C.4
Raes, M.5
Michiels, C.6
-
57
-
-
84856739946
-
Hypoxia-inducible factors in physiology and medicine
-
[CrossRef] [PubMed]
-
Semenza, G.L. Hypoxia-inducible factors in physiology and medicine. Cell 2012, 148, 399-408. [CrossRef] [PubMed]
-
(2012)
Cell
, vol.148
, pp. 399-408
-
-
Semenza, G.L.1
-
58
-
-
84896281040
-
Transcriptional repression of hypoxia-inducible factor-1 (HIF-1) by the protein arginine methyltransferase PRMT1
-
[CrossRef] [PubMed]
-
Lafleur, V.N.; Richard, S.; Richard, D.E. Transcriptional repression of hypoxia-inducible factor-1 (HIF-1) by the protein arginine methyltransferase PRMT1. Mol. Biol. Cell 2014, 25, 925-935. [CrossRef] [PubMed]
-
(2014)
Mol. Biol. Cell
, vol.25
, pp. 925-935
-
-
Lafleur, V.N.1
Richard, S.2
Richard, D.E.3
-
59
-
-
0037780902
-
Downregulation of CAP4 gene by von Hippel-Lindau tumor suppressor protein in human renal cancer cells
-
[CrossRef] [PubMed]
-
Masuda, K.; Ono, M.; Okamoto, M.; Morikawa, W.; Otsubo, M.; Migita, T.; Tsuneyoshi, M.; Okuda, H.; Shuin, T.; Naito, S.; et al. Downregulation of CAP4 gene by von Hippel-Lindau tumor suppressor protein in human renal cancer cells. Int. J. Cancer 2003, 105, 803-810. [CrossRef] [PubMed]
-
(2003)
Int. J. Cancer
, vol.105
, pp. 803-810
-
-
Masuda, K.1
Ono, M.2
Okamoto, M.3
Morikawa, W.4
Otsubo, M.5
Migita, T.6
Tsuneyoshi, M.7
Okuda, H.8
Shuin, T.9
Naito, S.10
-
60
-
-
84907914616
-
RAD9 deficiency enhances radiation induced bystander DNA damage and transcriptomal response
-
[CrossRef] [PubMed]
-
Ghandhi, S.A.; Ponnaiya, B.; Panigrahi, S.K.; Hopkins, K.M.; Cui, Q.; Hei, T.K.; Amundson, S.A.; Lieberman, H.B. RAD9 deficiency enhances radiation induced bystander DNA damage and transcriptomal response. Radiat. Oncol. 2014, 9, 206. [CrossRef] [PubMed]
-
(2014)
Radiat. Oncol.
, vol.9
, pp. 206
-
-
Ghandhi, S.A.1
Ponnaiya, B.2
Panigrahi, S.K.3
Hopkins, K.M.4
Cui, Q.5
Hei, T.K.6
Amundson, S.A.7
Lieberman, H.B.8
-
61
-
-
84864026646
-
The interplay between retinoic acid receptor-related orphan receptors and human diseases
-
[CrossRef] [PubMed]
-
Ranhotra, H.S. The interplay between retinoic acid receptor-related orphan receptors and human diseases. J. Recept. Signal Transduct. Res. 2012, 32, 181-189. [CrossRef] [PubMed]
-
(2012)
J. Recept. Signal Transduct. Res.
, vol.32
, pp. 181-189
-
-
Ranhotra, H.S.1
-
62
-
-
73349137289
-
Emerging roles of Kruppel-like factor 6 and Kruppel-like factor 6 splice variant 1 in ovarian cancer progression and treatment
-
[CrossRef] [PubMed]
-
DiFeo, A.; Narla, G.; Martignetti, J.A. Emerging roles of Kruppel-like factor 6 and Kruppel-like factor 6 splice variant 1 in ovarian cancer progression and treatment. Mt. Sinai J. Med. 2009, 76, 557-566. [CrossRef] [PubMed]
-
(2009)
Mt. Sinai J. Med.
, vol.76
, pp. 557-566
-
-
DiFeo, A.1
Narla, G.2
Martignetti, J.A.3
-
63
-
-
76649107927
-
The emerging role of Krüppel-like factors in endocrine-responsive cancers of female reproductive tissues
-
[CrossRef] [PubMed]
-
Simmen, R.C.M.; Pabona, J.M.P.; Velarde, M.C.; Simmons, C.; Rahal, O.; Simmen, F.A. The emerging role of Krüppel-like factors in endocrine-responsive cancers of female reproductive tissues. J. Endocrinol. 2010, 204, 223-231. [CrossRef] [PubMed]
-
(2010)
J. Endocrinol.
, vol.204
, pp. 223-231
-
-
Simmen, R.C.M.1
Pabona, J.M.P.2
Velarde, M.C.3
Simmons, C.4
Rahal, O.5
Simmen, F.A.6
-
64
-
-
12344252237
-
AP-1 subunits: Quarrel and harmony among siblings
-
[CrossRef] [PubMed]
-
Hess, J.; Angel, P.; Schorpp-Kistner, M. AP-1 subunits: Quarrel and harmony among siblings. J. Cell Sci. 2004, 117, 5965-5973. [CrossRef] [PubMed]
-
(2004)
J. Cell Sci.
, vol.117
, pp. 5965-5973
-
-
Hess, J.1
Angel, P.2
Schorpp-Kistner, M.3
-
65
-
-
77949916262
-
AP-1-the Jun proteins: Oncogene or tumor suppressors in disguise?
-
Shaurian, E. AP-1-the Jun proteins: Oncogene or tumor suppressors in disguise? Cell Signal. 2010, 22, 894-899.
-
(2010)
Cell Signal.
, vol.22
, pp. 894-899
-
-
Shaurian, E.1
-
66
-
-
84926637320
-
Critical protein GAPDH and its regulatory mechanisms in cancer cells
-
[PubMed]
-
Zhang, J.-Y.; Zhang, F.; Hong, C.-Q.; Giuliano, A.E.; Cui, X.-J.; Zhou, G.-J.; Zhang, G.-J.; Cui, Y.K. Critical protein GAPDH and its regulatory mechanisms in cancer cells. Cancer Biol. Med. 2015, 12, 10-22. [PubMed]
-
(2015)
Cancer Biol. Med.
, vol.12
, pp. 10-22
-
-
Zhang, J.-Y.1
Zhang, F.2
Hong, C.-Q.3
Giuliano, A.E.4
Cui, X.-J.5
Zhou, G.-J.6
Zhang, G.-J.7
Cui, Y.K.8
-
67
-
-
84920913704
-
Elevated levels of 14-3-3 proteins, serotonin, gamma enolase and pyruvate kinase identified in clinical samples from patients diagnosed with colorectal cancer
-
[CrossRef] [PubMed]
-
Dowling, P.; Hughes, D.J.; Larkin, A.M.; Meiller, J.; Henry, M.; Meleady, P.; Lynch, V.; Pardini, B.; Naccarati, A.; Levy, M.; et al. Elevated levels of 14-3-3 proteins, serotonin, gamma enolase and pyruvate kinase identified in clinical samples from patients diagnosed with colorectal cancer. Clin. Chim. Acta 2015, 441, 133-141. [CrossRef] [PubMed]
-
(2015)
Clin. Chim. Acta
, vol.441
, pp. 133-141
-
-
Dowling, P.1
Hughes, D.J.2
Larkin, A.M.3
Meiller, J.4
Henry, M.5
Meleady, P.6
Lynch, V.7
Pardini, B.8
Naccarati, A.9
Levy, M.10
-
68
-
-
79955398591
-
Otto Warburg's contributions to current concepts of cancer metabolism
-
[CrossRef] [PubMed]
-
Koppenol, W.H.; Bounds, P.L.; Dang, C.V. Otto Warburg's contributions to current concepts of cancer metabolism. Nat. Rev. Cancer 2011, 11, 325-337. [CrossRef] [PubMed]
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 325-337
-
-
Koppenol, W.H.1
Bounds, P.L.2
Dang, C.V.3
-
69
-
-
77954697566
-
Isocitrate dehydrogenase 1 and 2 mutations in cancer: Alterations at crossroads of cellular metabolism
-
[CrossRef] [PubMed]
-
Reitman, Z.J.; Yan, H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: Alterations at crossroads of cellular metabolism. J. Natl. Cancer Inst. 2010, 102, 932-941. [CrossRef] [PubMed]
-
(2010)
J. Natl. Cancer Inst.
, vol.102
, pp. 932-941
-
-
Reitman, Z.J.1
Yan, H.2
-
71
-
-
84855181728
-
How do tenacins influence the birth and life of a malignant cell?
-
[CrossRef] [PubMed]
-
Brellier, F.; Chiquet-Ehrismann, R. How do tenacins influence the birth and life of a malignant cell? J. Cell. Mol. Med. 2012, 16, 32-40. [CrossRef] [PubMed]
-
(2012)
J. Cell. Mol. Med.
, vol.16
, pp. 32-40
-
-
Brellier, F.1
Chiquet-Ehrismann, R.2
-
72
-
-
84952012375
-
High-level secretion of tissue factor-rich extracellular vesicles from ovarian cancer cells mediated by filamin-A and protease-activated receptors
-
[CrossRef] [PubMed]
-
Koizume, S.; Ito, S.; Yoshioka, Y.; Kanayama, T.; Nakamura, Y.; Yoshihara, M.; Yamada, R.; Ochiya, T.; Ruf,W.; Miyagi, E.; et al. High-level secretion of tissue factor-rich extracellular vesicles from ovarian cancer cells mediated by filamin-A and protease-activated receptors. Thromb. Haemost. 2015. [CrossRef] [PubMed]
-
(2015)
Thromb. Haemost.
-
-
Koizume, S.1
Ito, S.2
Yoshioka, Y.3
Kanayama, T.4
Nakamura, Y.5
Yoshihara, M.6
Yamada, R.7
Ochiya, T.8
Ruf, W.9
Miyagi, E.10
-
73
-
-
84929716213
-
Cellular and molecular mechanisms underlying oxygen-dependent radiosensitivity
-
[CrossRef] [PubMed]
-
Liu, C.; Lin, Q.; Yun, Z. Cellular and molecular mechanisms underlying oxygen-dependent radiosensitivity. Radiat. Res. 2015, 183, 487-496. [CrossRef] [PubMed]
-
(2015)
Radiat. Res.
, vol.183
, pp. 487-496
-
-
Liu, C.1
Lin, Q.2
Yun, Z.3
-
74
-
-
79957534572
-
Targeting hypoxia in cancer therapy
-
[CrossRef] [PubMed]
-
Wilson,W.R.; Hay, M.P. Targeting hypoxia in cancer therapy. Nat. Rev. Cancer 2011, 11, 393-410. [CrossRef] [PubMed]
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 393-410
-
-
Wilson, W.R.1
Hay, M.P.2
-
75
-
-
84883501150
-
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
-
[CrossRef] [PubMed]
-
Semenza, G.L. HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations. J. Clin. Investig. 2013, 123, 3664-3671. [CrossRef] [PubMed]
-
(2013)
J. Clin. Investig.
, vol.123
, pp. 3664-3671
-
-
Semenza, G.L.1
|