HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells

Nucleic Acids Research

Volumn 40, Issue 12, 2012, Pages 5389-5401

  Koizume, Shiro ^a   Ito, Shin ^a   Miyagi, Etsuko ^b   Hirahara, Fumiki ^b   Nakamura, Yoshiyasu ^a   Sakuma, Yuji ^a   Osaka, Hitoshi ^c   Takano, Yasuo ^a   Ruf, Wolfram ^d   Miyagi, Yohei ^a  

^a KANAGAWA CANCER CENTER   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c KANAGAWA CHILDREN'S MEDICAL CENTER   (Japan)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE 4; HYPOXIA INDUCIBLE FACTOR 2ALPHA; PROTEIN P300; TRANSCRIPTION FACTOR SP1;

ARTICLE; BINDING SITE; BLOOD COAGULATION FACTOR 7 GENE; CELL HYPOXIA; CLEAR CELL CARCINOMA; CONTROLLED STUDY; DEACETYLATION; FEMALE; GENE; GENE ACTIVATION; GENE INDUCTION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; OVARY CANCER; OVARY CELL CULTURE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UNFOLDED PROTEIN RESPONSE;

ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; CELL HYPOXIA; CELL LINE, TUMOR; CULTURE MEDIA, SERUM-FREE; FACTOR VII; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSE; HISTONE DEACETYLASES; HUMANS; OVARIAN NEOPLASMS; REPRESSOR PROTEINS; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION; UNFOLDED PROTEIN RESPONSE;

EID: 84863223765     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks201     Document Type: Article

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