Translational and transcriptional control of Sp1 against ischaemia through a hydrogen peroxide-activated internal ribosomal entry site pathway

Nucleic Acids Research

Volumn 39, Issue 13, 2011, Pages 5412-5423

  Yeh, Shiu Hwa ^a   Yang, Wen Bin ^b   Gean, Po Wu ^a,b   Hsu, Chung Yi ^b   Tseng, Joseph T ^b,c   Su, Tsung Ping ^a   Chang, Wen Chang ^a,b   Hung, Jan Jong ^a,b  

^a Department of Pharmacology ^*  (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; MESSENGER RNA; SHORT HAIRPIN RNA; TEMPOL; TRANSCRIPTION FACTOR SP1;

5' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX LESION; BRAIN ISCHEMIA; BRAIN LEVEL; CONTROLLED STUDY; INTERNAL RIBOSOME ENTRY SITE; MALE; NERVE CELL; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

5' UNTRANSLATED REGIONS; ANIMALS; BRAIN ISCHEMIA; GLUCOSE; HUMANS; HYDROGEN PEROXIDE; MALE; NEURONS; OXYGEN; PROTEIN BIOSYNTHESIS; RATS; RIBOSOMES; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

RATTUS;

EID: 80052226694     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr161     Document Type: Article

References (36)

1. Blaszczyk, L., Dutkiewicz, M. and Ciesiolka, J. (2007) [Translation of eukaryotic mRNA in a cap-independent mode]. Postepy Biochem., 53, 400-412.
2. Dinkova, T.D., Zepeda, H., Martinez-Salas, E., Martinez, L.M., Nieto-Sotelo, J. and de Jimenez, E.S. (2005) Cap-independent translation of maize Hsp101. Plant J., 41, 722-731. (Pubitemid 40336003)
3. Bornes, S., Prado-Lourenco, L., Bastide, A., Zanibellato, C., Iacovoni, J.S., Lacazette, E., Prats, A.C., Touriol, C. and Prats, H. (2007) Translational induction of VEGF internal ribosome entry site elements during the early response to ischemic stress. Circ. Res., 100, 305-308.
4. Conte, C., Riant, E., Toutain, C., Pujol, F., Arnal, J.F., Lenfant, F. and Prats, A.C. (2008) FGF2 translationally induced by hypoxia is involved in negative and positive feedback loops with HIF-1alpha. PLoS ONE, 3, e3078.
5. Briggs, M.R., Kadonaga, J.T., Bell, S.P. and Tjian, R. (1986) Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science, 234, 47-52. (Pubitemid 17171544)
6. Lania, L., Majello, B. and De Luca, P. (1997) Transcriptional regulation by the Sp family proteins. Int. J. Biochem. Cell. Biol., 29, 1313-1323. (Pubitemid 28153485)
7. Suske, G. (1999) The Sp-family of transcription factors. Gene, 238, 291-300. (Pubitemid 29446168)
8. Yang, Y., Hwang, C.K., Junn, E., Lee, G. and Mouradian, M.M. (2000) ZIC2 and Sp3 repress Sp1-induced activation of the human D1A dopamine receptor gene. J. Biol. Chem., 275, 38863-38869. (Pubitemid 32009224)
9. Dunah, A.W., Jeong, H., Griffin, A., Kim, Y.M., Standaert, D.G., Hersch, S.M., Mouradian, M.M., Young, A.B., Tanese, N. and Krainc, D. (2002) Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science, 296, 2238-2243. (Pubitemid 34680312)
10. Liu, Y.W., Tseng, H.P., Chen, L.C., Chen, B.K. and Chang, W.C. (2003) Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages. J. Immunol., 171, 821-828.
11. Nucifora, F.C. Jr, Sasaki, M., Peters, M.F., Huang, H., Cooper, J.K., Yamada, M., Takahashi, H., Tsuji, S., Troncoso, J., Dawson, V.L. et al. (2001) Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science, 291, 2423-2428. (Pubitemid 32231807)
12. Fridmacher, V., Kaltschmidt, B., Goudeau, B., Ndiaye, D., Rossi, F.M., Pfeiffer, J., Kaltschmidt, C., Israel, A. and Memet, S. (2003) Forebrain-specific neuronal inhibition of nuclear factor-kappaB activity leads to loss of neuroprotection. J. Neurosci., 23, 9403-9408. (Pubitemid 37323040)
13. Meissner, M., Stein, M., Urbich, C., Reisinger, K., Suske, G., Staels, B., Kaufmann, R. and Gille, J. (2004) PPARalpha activators inhibit vascular endothelial growth factor receptor-2 expression by repressing Sp1-dependent DNA binding and transactivation. Circ. Res., 94, 324-332. (Pubitemid 38240723)
14. Tanaka, T., Kanai, H., Sekiguchi, K., Aihara, Y., Yokoyama, T., Arai, M., Kanda, T., Nagai, R. and Kurabayashi, M. (2000) Induction of VEGF gene transcription by IL-1 beta is mediated through stress-activated MAP kinases and Sp1 sites in cardiac myocytes. J. Mol. Cell. Cardiol., 32, 1955-1967.
15. Lee, J., Kosaras, B., Aleyasin, H., Han, J.A., Park, D.S., Ratan, R.R., Kowall, N.W., Ferrante, R.J., Lee, S.W. and Ryu, H. (2006) Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response. FASEB J., 20, 2375-2377.
16. Ryu, H., Lee, J., Zaman, K., Kubilis, J., Ferrante, R.J., Ross, B.D., Neve, R. and Ratan, R.R. (2003) Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons. J. Neurosci., 23, 3597-3606. (Pubitemid 36958467)
17. Lee, M., Bikram, M., Oh, S., Bull, D.A. and Kim, S.W. (2004) Sp1-dependent regulation of the RTP801 promoter and its application to hypoxia-inducible VEGF plasmid for ischemic disease. Pharm. Res., 21, 736-741. (Pubitemid 39011293)
18. Miki, N., Ikuta, M. and Matsui, T. (2004) Hypoxia-induced activation of the retinoic acid receptor-related orphan receptor alpha4 gene by an interaction between hypoxia-inducible factor-1 and Sp1. J. Biol. Chem., 279, 15025-15031. (Pubitemid 38618895)
19. Eltzschig, H.K., Kohler, D., Eckle, T., Kong, T., Robson, S.C. and Colgan, S.P. (2009) Central role of Sp1-regulated CD39 in hypoxia/ischemia protection. Blood, 113, 224-232.
20. Kiryu-Seo, S., Kato, R., Ogawa, T., Nakagomi, S., Nagata, K. and Kiyama, H. (2008) Neuronal injury-inducible gene is synergistically regulated by ATF3, c-Jun, and STAT3 through the interaction with Sp1 in damaged neurons. J. Biol. Chem., 283, 6988-6996.
21. Simard, J.M., Chen, M., Tarasov, K.V., Bhatta, S., Ivanova, S., Melnitchenko, L., Tsymbalyuk, N., West, G.A. and Gerzanich, V. (2006) Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke. Nat. Med., 12, 433-440.
22. Emerling, B.M., Platanias, L.C., Black, E., Nebreda, A.R., Davis, R.J. and Chandel, N.S. (2005) Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. Mol. Cell. Biol., 25, 4853-4862. (Pubitemid 40781087)
23. Guzy, R.D., Hoyos, B., Robin, E., Chen, H., Liu, L., Mansfield, K.D., Simon, M.C., Hammerling, U. and Schumacker, P.T. (2005) Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab., 1, 401-408. (Pubitemid 43960623)
24. Sheldon, R.A., Aminoff, A., Lee, C.L., Christen, S. and Ferriero, D.M. (2007) Hypoxic preconditioning reverses protection after neonatal hypoxia-ischemia in glutathione peroxidase transgenic murine brain. Pediatr. Res., 61, 666-670. (Pubitemid 46800273)
25. Furuichi, T., Liu, W., Shi, H., Miyake, M. and Liu, K.J. (2005) Generation of hydrogen peroxide during brief oxygen-glucose deprivation induces preconditioning neuronal protection in primary cultured neurons. J. Neurosci. Res., 79, 816-824. (Pubitemid 40476506)
26. Bonello, S., Zahringer, C., BelAiba, R.S., Djordjevic, T., Hess, J., Michiels, C., Kietzmann, T. and Gorlach, A. (2007) Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site. Arterioscler. Thromb. Vasc. Biol., 27, 755-761. (Pubitemid 46606703)
27. Macrae, I.M., Robinson, M.J., Graham, D.I., Reid, J.L. and McCulloch, J. (1993) Endothelin-1-induced reductions in cerebral blood flow: dose dependency, time course, and neuropathological consequences. J. Cereb. Blood Flow Metab., 13, 276-284. (Pubitemid 23067462)
28. Sharkey, J., Ritchie, I.M. and Kelly, P.A. (1993) Perivascular microapplication of endothelin-1: a new model of focal cerebral ischaemia in the rat. J. Cereb. Blood Flow Metab., 13, 865-871. (Pubitemid 23244756)
29. Bogaert, L., Scheller, D., Moonen, J., Sarre, S., Smolders, I., Ebinger, G. and Michotte, Y. (2000) Neurochemical changes and laser Doppler flowmetry in the endothelin-1 rat model for focal cerebral ischemia. Brain Res., 887, 266-275. (Pubitemid 32008048)
30. Stoneley, M., Paulin, F.E., Le Quesne, J.P., Chappell, S.A. and Willis, A.E. (1998) C-Myc 50 untranslated region contains an internal ribosome entry segment. Oncogene, 16, 423-428. (Pubitemid 28052297)
31. Holcik, M. and Korneluk, R.G. (2000) Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: role of La autoantigen in XIAP translation. Mol. Cell Biol., 20, 4648-4657. (Pubitemid 30396112)
32. Holcik, M., Gordon, B.W. and Korneluk, R.G. (2003) The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2. Mol. Cell. Biol., 23, 280-288. (Pubitemid 36008520)
33. Dasari, A., Bartholomew, J.N., Volonte, D. and Galbiati, F. (2006) Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elements. Cancer Res., 66, 10805-10814. (Pubitemid 44876976)
34. Qiu, Z., Norflus, F., Singh, B., Swindell, M.K., Buzescu, R., Bejarano, M., Chopra, R., Zucker, B., Benn, C.L., DiRocco, D.P. et al. (2006) Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective. J. Biol. Chem., 281, 16672-16680.
35. Zhai, W., Jeong, H., Cui, L., Krainc, D. and Tjian, R. (2005) In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets. Cell, 123, 1241-1253. (Pubitemid 41821782)
36. Santpere, G., Nieto, M., Puig, B. and Ferrer, I. (2006) Abnormal Sp1 transcription factor expression in Alzheimer disease and tauopathies. Neurosci. Lett., 397, 30-34. (Pubitemid 43340453)