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Volumn 68, Issue 12, 2008, Pages 4919-4927

Insulin-dependent leptin expression in breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; INSULIN; LEPTIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1; ANTIDIABETIC AGENT; HIF1A PROTEIN, HUMAN; LUCIFERASE;

EID: 49649100035     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-0642     Document Type: Article
Times cited : (65)

References (49)
  • 1
    • 4444237280 scopus 로고    scopus 로고
    • Obesity and cancer
    • Calle EE, Thun MJ. Obesity and cancer. Oncogene 2004;23:6365-78.
    • (2004) Oncogene , vol.23 , pp. 6365-6378
    • Calle, E.E.1    Thun, M.J.2
  • 2
    • 33947537241 scopus 로고    scopus 로고
    • Mechanisms of disease: Adipokines and breast cancer - endocrine and paracrine mechanisms that connect adiposity and breast cancer
    • Schaffler A, Scholmerich J, Buechler C. Mechanisms of disease: adipokines and breast cancer - endocrine and paracrine mechanisms that connect adiposity and breast cancer. Nat Clin Pract Endocrinol Metab 2007;3:345-54.
    • (2007) Nat Clin Pract Endocrinol Metab , vol.3 , pp. 345-354
    • Schaffler, A.1    Scholmerich, J.2    Buechler, C.3
  • 3
    • 34248157798 scopus 로고    scopus 로고
    • Obesity hormone leptin: A new target in breast cancer?
    • Surmacz E. Obesity hormone leptin: a new target in breast cancer? Breast Cancer Res 2007;9:301.
    • (2007) Breast Cancer Res , vol.9 , pp. 301
    • Surmacz, E.1
  • 4
    • 33745106287 scopus 로고    scopus 로고
    • Molecular links between obesity and breast cancer
    • Lorincz AM, Sukumar S. Molecular links between obesity and breast cancer. Endocr Relat Cancer 2006;13:279-92.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 279-292
    • Lorincz, A.M.1    Sukumar, S.2
  • 5
    • 34547741589 scopus 로고    scopus 로고
    • Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression
    • Vona-Davis L, Rose DP. Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression. Endocr Relat Cancer 2007;14:189-206.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 189-206
    • Vona-Davis, L.1    Rose, D.P.2
  • 8
    • 34248147408 scopus 로고    scopus 로고
    • Evidences that leptin up-regulates E-cadherin expression in breast cancer: Effects on tumor growth and progression
    • Mauro L, Catalano S, Bossi G, et al. Evidences that leptin up-regulates E-cadherin expression in breast cancer: effects on tumor growth and progression. Cancer Res 2007;67:3412-21.
    • (2007) Cancer Res , vol.67 , pp. 3412-3421
    • Mauro, L.1    Catalano, S.2    Bossi, G.3
  • 9
    • 34250315764 scopus 로고    scopus 로고
    • Leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3
    • Saxena NK, Vertino PM, Anania FA, Sharma D. Leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. J Biol Chem 2007;282:13316-25.
    • (2007) J Biol Chem , vol.282 , pp. 13316-13325
    • Saxena, N.K.1    Vertino, P.M.2    Anania, F.A.3    Sharma, D.4
  • 10
    • 33645066625 scopus 로고    scopus 로고
    • Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: Possible role of obesity-related stimuli
    • Garofalo C, Koda M, Cascio S, et al. Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli. Clin Cancer Res 2006;12:1447-53.
    • (2006) Clin Cancer Res , vol.12 , pp. 1447-1453
    • Garofalo, C.1    Koda, M.2    Cascio, S.3
  • 11
    • 3042817487 scopus 로고    scopus 로고
    • Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer
    • Ishikawa M, Kitayama J, Nagawa H. Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer. Clin Cancer Res 2004;10:4325-31.
    • (2004) Clin Cancer Res , vol.10 , pp. 4325-4331
    • Ishikawa, M.1    Kitayama, J.2    Nagawa, H.3
  • 12
    • 33646264086 scopus 로고    scopus 로고
    • Messenger RNA expression of leptin and leptin receptors and their prognostic value in 322 human primary breast cancers
    • Revillion F, Charlier M, Lhotellier V, et al. Messenger RNA expression of leptin and leptin receptors and their prognostic value in 322 human primary breast cancers. Clin Cancer Res 2006;12:2088-94.
    • (2006) Clin Cancer Res , vol.12 , pp. 2088-2094
    • Revillion, F.1    Charlier, M.2    Lhotellier, V.3
  • 15
    • 0030032754 scopus 로고    scopus 로고
    • Genomic structure and promoter analysis of the human obese gene
    • Gong DW, Bi S, Pratley RE, Weintraub BD. Genomic structure and promoter analysis of the human obese gene. J Biol Chem 1996;271:3971-4.
    • (1996) J Biol Chem , vol.271 , pp. 3971-3974
    • Gong, D.W.1    Bi, S.2    Pratley, R.E.3    Weintraub, B.D.4
  • 16
    • 34248145523 scopus 로고    scopus 로고
    • Sp1 and Sp3 regulate glucokinase gene transcription in the liver of gilthead sea bream (Sparus aurata)
    • Egea M, Meton I, Baanante IV. Sp1 and Sp3 regulate glucokinase gene transcription in the liver of gilthead sea bream (Sparus aurata). J Mol Endocrinol 2007;38:481-92.
    • (2007) J Mol Endocrinol , vol.38 , pp. 481-492
    • Egea, M.1    Meton, I.2    Baanante, I.V.3
  • 17
    • 17344395628 scopus 로고    scopus 로고
    • Synergistic effects of hypoxia and insulin are regulated by different transcriptional elements of the human leptin promoter
    • Meissner U, Ostreicher I, Allabauer I, Rascher W, Dotsch J. Synergistic effects of hypoxia and insulin are regulated by different transcriptional elements of the human leptin promoter. Biochem Biophys Res Commun 2003;303:707-12.
    • (2003) Biochem Biophys Res Commun , vol.303 , pp. 707-712
    • Meissner, U.1    Ostreicher, I.2    Allabauer, I.3    Rascher, W.4    Dotsch, J.5
  • 19
    • 33846191455 scopus 로고    scopus 로고
    • Activation of the nuclear transcription factor SP-1 by insulin rapidly increases the expression of protein kinase C δ in skeletal muscle
    • Horovitz-Fried M, Jacob AI, Cooper DR, Sampson SR. Activation of the nuclear transcription factor SP-1 by insulin rapidly increases the expression of protein kinase C δ in skeletal muscle. Cell Signal 2007;19:556-62.
    • (2007) Cell Signal , vol.19 , pp. 556-562
    • Horovitz-Fried, M.1    Jacob, A.I.2    Cooper, D.R.3    Sampson, S.R.4
  • 20
    • 0035957910 scopus 로고    scopus 로고
    • Epidermal growth factor induction of apolipoprotein A-I is mediated by the Ras-MAP kinase cascade and Sp1
    • Zheng XL, Matsubara S, Diao C, Hollenberg MD, Wong NC. Epidermal growth factor induction of apolipoprotein A-I is mediated by the Ras-MAP kinase cascade and Sp1. J Biol Chem 2001;276:13822-9.
    • (2001) J Biol Chem , vol.276 , pp. 13822-13829
    • Zheng, X.L.1    Matsubara, S.2    Diao, C.3    Hollenberg, M.D.4    Wong, N.C.5
  • 21
    • 0033521115 scopus 로고    scopus 로고
    • Transcriptional regulation of endothelial nitric-oxide synthase by an interaction between casein kinase 2 and protein phosphatase 2A
    • Cieslik K, Lee CM, Tang JL, Wu KK. Transcriptional regulation of endothelial nitric-oxide synthase by an interaction between casein kinase 2 and protein phosphatase 2A. J Biol Chem 1999;274:34669-75.
    • (1999) J Biol Chem , vol.274 , pp. 34669-34675
    • Cieslik, K.1    Lee, C.M.2    Tang, J.L.3    Wu, K.K.4
  • 22
    • 33751169387 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 (HIF-1)
    • Ke Q, Costa M. Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol 2006;70:1469-80.
    • (2006) Mol Pharmacol , vol.70 , pp. 1469-1480
    • Ke, Q.1    Costa, M.2
  • 23
    • 33745138232 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia-inducible factor 1
    • Hirota K, Semenza GL. Regulation of angiogenesis by hypoxia-inducible factor 1. Crit Rev Oncol Hematol 2006;59:15-26.
    • (2006) Crit Rev Oncol Hematol , vol.59 , pp. 15-26
    • Hirota, K.1    Semenza, G.L.2
  • 24
    • 0033566693 scopus 로고    scopus 로고
    • Reciprocal positive regulation of hypoxia-inducible factor 1α and insulin-like growth factor 2
    • Feldser D, Agani F, Iyer NV, Pak B, Ferreira G, Semenza GL. Reciprocal positive regulation of hypoxia-inducible factor 1α and insulin-like growth factor 2. Cancer Res 1999;59:3915-8.
    • (1999) Cancer Res , vol.59 , pp. 3915-3918
    • Feldser, D.1    Agani, F.2    Iyer, N.V.3    Pak, B.4    Ferreira, G.5    Semenza, G.L.6
  • 25
    • 0032725554 scopus 로고    scopus 로고
    • p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1α (HIF-1α) and enhance the transcriptional activity of HIF-1
    • Richard DE, Berra E, Gothie E, Roux D, Pouyssegur J. p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1α (HIF-1α) and enhance the transcriptional activity of HIF-1. J Biol Chem 1999;274:32631-7.
    • (1999) J Biol Chem , vol.274 , pp. 32631-32637
    • Richard, D.E.1    Berra, E.2    Gothie, E.3    Roux, D.4    Pouyssegur, J.5
  • 26
    • 0033606042 scopus 로고    scopus 로고
    • CBP associates with the p42/p44 MAPK enzymes and is phosphorylated following NGF treatment
    • Liu YZ, Thomas NS, Latchman DS. CBP associates with the p42/p44 MAPK enzymes and is phosphorylated following NGF treatment. Neuroreport 1999;10:1239-43.
    • (1999) Neuroreport , vol.10 , pp. 1239-1243
    • Liu, Y.Z.1    Thomas, N.S.2    Latchman, D.S.3
  • 27
    • 0037515549 scopus 로고    scopus 로고
    • MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
    • Sang N, Stiehl DP, Bohensky J, Leshchinsky I, Srinivas V, Caro J. MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300. J Biol Chem 2003;278:14013-9.
    • (2003) J Biol Chem , vol.278 , pp. 14013-14019
    • Sang, N.1    Stiehl, D.P.2    Bohensky, J.3    Leshchinsky, I.4    Srinivas, V.5    Caro, J.6
  • 28
    • 0033964512 scopus 로고    scopus 로고
    • p300 collaborates with Sp1 and Sp3 in p21(waf1/cip1) promoter activation induced by histone deacetylase inhibitor
    • Xiao H, Hasegawa T, Isobe K. p300 collaborates with Sp1 and Sp3 in p21(waf1/cip1) promoter activation induced by histone deacetylase inhibitor. J Biol Chem 2000;275:1371-6.
    • (2000) J Biol Chem , vol.275 , pp. 1371-1376
    • Xiao, H.1    Hasegawa, T.2    Isobe, K.3
  • 29
    • 0031835957 scopus 로고    scopus 로고
    • Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein
    • Ebert BL, Bunn HF. Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein. Mol Cell Biol 1998;18:4089-96.
    • (1998) Mol Cell Biol , vol.18 , pp. 4089-4096
    • Ebert, B.L.1    Bunn, H.F.2
  • 30
    • 18844444774 scopus 로고    scopus 로고
    • HIF-1α, STAT3, CBP/ p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
    • Gray MJ, Zhang J, Ellis LM, et al. HIF-1α, STAT3, CBP/ p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene 2005;24:3110-20.
    • (2005) Oncogene , vol.24 , pp. 3110-3120
    • Gray, M.J.1    Zhang, J.2    Ellis, L.M.3
  • 32
    • 38349080768 scopus 로고    scopus 로고
    • Mechanism of leptin expression in breast cancer cells: Role of hypoxia-inducible factor-1α
    • Cascio S, Bartella V, Auriemma A, et al. Mechanism of leptin expression in breast cancer cells: role of hypoxia-inducible factor-1α. Oncogene 2008;27:540-7.
    • (2008) Oncogene , vol.27 , pp. 540-547
    • Cascio, S.1    Bartella, V.2    Auriemma, A.3
  • 33
    • 0035884617 scopus 로고    scopus 로고
    • Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells
    • Bartucci M, Morelli C, Mauro L, Ando S, Surmacz E. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells. Cancer Res 2001;61:6747-54.
    • (2001) Cancer Res , vol.61 , pp. 6747-6754
    • Bartucci, M.1    Morelli, C.2    Mauro, L.3    Ando, S.4    Surmacz, E.5
  • 34
    • 6344279925 scopus 로고    scopus 로고
    • Nuclear insulin receptor substrate 1 interacts with estrogen receptor α at ERE promoters
    • Morelli C, Garofalo C, Sisci D, et al. Nuclear insulin receptor substrate 1 interacts with estrogen receptor α at ERE promoters. Oncogene 2004;23:7517-26.
    • (2004) Oncogene , vol.23 , pp. 7517-7526
    • Morelli, C.1    Garofalo, C.2    Sisci, D.3
  • 35
    • 0029972928 scopus 로고    scopus 로고
    • The adipocyte specific transcription factor C/EBPα modulates human ob gene expression
    • Miller SG, De Vos P, Guerre-Millo M, et al. The adipocyte specific transcription factor C/EBPα modulates human ob gene expression. Proc Natl Acad Sci U S A 1996;93:5507-11.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5507-5511
    • Miller, S.G.1    De Vos, P.2    Guerre-Millo, M.3
  • 36
    • 33947493624 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells
    • Cascio S, Bartella V, Garofalo C, Russo A, Giordano A, Surmacz E. Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells. J Biol Chem 2007;282:3498-506.
    • (2007) J Biol Chem , vol.282 , pp. 3498-3506
    • Cascio, S.1    Bartella, V.2    Garofalo, C.3    Russo, A.4    Giordano, A.5    Surmacz, E.6
  • 37
    • 33947498749 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 mediates effects of insulin on pancreatic cancer cells and disturbs host energy homeostasis
    • Wang F, Li SS, Segersvard R, et al. Hypoxia inducible factor-1 mediates effects of insulin on pancreatic cancer cells and disturbs host energy homeostasis. Am J Pathol 2007;170:469-77.
    • (2007) Am J Pathol , vol.170 , pp. 469-477
    • Wang, F.1    Li, S.S.2    Segersvard, R.3
  • 38
    • 34247607209 scopus 로고    scopus 로고
    • The MAPK pathway and HIF-1 are involved in the induction of the human PAI-1 gene expression by insulin in the human hepatoma cell line HepG2
    • Dimova EY, Kietzmann T. The MAPK pathway and HIF-1 are involved in the induction of the human PAI-1 gene expression by insulin in the human hepatoma cell line HepG2. Ann N Y Acad Sci 2006;1090:355-67.
    • (2006) Ann N Y Acad Sci , vol.1090 , pp. 355-367
    • Dimova, E.Y.1    Kietzmann, T.2
  • 40
    • 0032169214 scopus 로고    scopus 로고
    • Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1α/ARNT
    • Zelzer E, Levy Y, Kahana C, Shilo BZ, Rubinstein M, Cohen B. Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1α/ARNT. EMBO J 1998;17:5085-94.
    • (1998) EMBO J , vol.17 , pp. 5085-5094
    • Zelzer, E.1    Levy, Y.2    Kahana, C.3    Shilo, B.Z.4    Rubinstein, M.5    Cohen, B.6
  • 41
    • 34047250349 scopus 로고    scopus 로고
    • Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells
    • Saxena NK, Sharma D, Ding X, et al. Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells. Cancer Res 2007;67:2497-507.
    • (2007) Cancer Res , vol.67 , pp. 2497-2507
    • Saxena, N.K.1    Sharma, D.2    Ding, X.3
  • 42
    • 33745886839 scopus 로고    scopus 로고
    • Leptin-induced growth of human ZR-75-1 breast cancer cells is associated with up-regulation of cyclin D1 and c-Myc and down-regulation of tumor suppressor p53 and p21WAF1/ CIP1
    • Chen C, Chang YC, Liu CL, Chang KJ, Guo IC. Leptin-induced growth of human ZR-75-1 breast cancer cells is associated with up-regulation of cyclin D1 and c-Myc and down-regulation of tumor suppressor p53 and p21WAF1/ CIP1. Breast Cancer Res Treat 2006;98:121-32.
    • (2006) Breast Cancer Res Treat , vol.98 , pp. 121-132
    • Chen, C.1    Chang, Y.C.2    Liu, C.L.3    Chang, K.J.4    Guo, I.C.5
  • 43
    • 0033981845 scopus 로고    scopus 로고
    • ERK activation upon hypoxia: Involvement in HIF-1 activation
    • Minet E, Arnould T, Michel G, et al. ERK activation upon hypoxia: involvement in HIF-1 activation. FEBS Lett 2000;468:53-8.
    • (2000) FEBS Lett , vol.468 , pp. 53-58
    • Minet, E.1    Arnould, T.2    Michel, G.3
  • 45
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • Semenza GL. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol Med 2002;8:S62-7.
    • (2002) Trends Mol Med , vol.8
    • Semenza, G.L.1
  • 46
    • 0036139795 scopus 로고    scopus 로고
    • HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: Role of MAP kinases
    • Michiels C, Minet E, Michel G, Mottet D, Piret JP, Raes M. HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases. IUBMB Life 2001;52:49-53.
    • (2001) IUBMB Life , vol.52 , pp. 49-53
    • Michiels, C.1    Minet, E.2    Michel, G.3    Mottet, D.4    Piret, J.P.5    Raes, M.6
  • 47
    • 34047174592 scopus 로고    scopus 로고
    • The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer
    • Belfiore A. The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer. Curr Pharm Des 2007;13:671-86.
    • (2007) Curr Pharm Des , vol.13 , pp. 671-686
    • Belfiore, A.1
  • 48
    • 33751413087 scopus 로고    scopus 로고
    • Involvement of PKCα in insulin-induced PKCδ expression: Importance of SP-1 and NFκB transcription factors
    • Horovitz-Fried M, Sampson SR. Involvement of PKCα in insulin-induced PKCδ expression: Importance of SP-1 and NFκB transcription factors. Biochem Biophys Res Commun 2007;352:78-83.
    • (2007) Biochem Biophys Res Commun , vol.352 , pp. 78-83
    • Horovitz-Fried, M.1    Sampson, S.R.2
  • 49
    • 8544284095 scopus 로고    scopus 로고
    • Role of estrogen receptor α in modulating IGF-I receptor signaling and function in breast cancer
    • Surmacz E, Bartucci M. Role of estrogen receptor α in modulating IGF-I receptor signaling and function in breast cancer. J Exp Clin Cancer Res 2004;23:385-94.
    • (2004) J Exp Clin Cancer Res , vol.23 , pp. 385-394
    • Surmacz, E.1    Bartucci, M.2


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