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Volumn 14, Issue 12, 2015, Pages 1835-1844

Statins and their increased risk of inducing diabetes

Author keywords

cardiovascular disease; new onset diabetes; statin

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ANGIOTENSIN RECEPTOR ANTAGONIST; ATORVASTATIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; EZETIMIBE PLUS SIMVASTATIN; FLUINDOSTATIN; GLUCOSE; GLUCOSE TRANSPORTER 1; GLYCERYL TRINITRATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PITAVASTATIN; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN; THIAZIDE DIURETIC AGENT;

EID: 84951907420     PISSN: 14740338     EISSN: 1744764X     Source Type: Journal    
DOI: 10.1517/14740338.2015.1096343     Document Type: Review
Times cited : (29)

References (89)
  • 1
    • 84897970506 scopus 로고    scopus 로고
    • 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • Stone NJ, Robinson JG, Lichtenstein AH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2014;129:S1-45
    • (2014) Circulation , vol.129 , pp. S1-45
    • Stone, N.J.1    Robinson, J.G.2    Lichtenstein, A.H.3
  • 2
    • 84905189482 scopus 로고    scopus 로고
    • Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: A meta-Analysis of statin trials
    • Boekholdt SM, Hovingh GK, Mora S, et al. Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: A meta-Analysis of statin trials. J Am Coll Cardiol 2014;64:485-94
    • (2014) J Am Coll Cardiol , vol.64 , pp. 485-494
    • Boekholdt, S.M.1    Hovingh, G.K.2    Mora, S.3
  • 3
  • 4
    • 4344683381 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): Multicentre randomised placebo-controlled trial
    • Colhoun HM, Betteridge DJ, Durrington PN, et al. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet 2004;364:685-96
    • (2004) Lancet , vol.364 , pp. 685-696
    • Colhoun, H.M.1    Betteridge, D.J.2    Durrington, P.N.3
  • 5
    • 84891764226 scopus 로고    scopus 로고
    • Reassessing the benefits of statins in the prevention of cardiovascular disease in diabetic patients-A systematic review and meta-Analysis
    • Chang YH, Hsieh MC, Wang CY, et al. Reassessing the benefits of statins in the prevention of cardiovascular disease in diabetic patients-A systematic review and meta-Analysis. Rev Diabet Stud 2013;10:157-70
    • (2013) Rev Diabet Stud , vol.10 , pp. 157-170
    • Chang, Y.H.1    Hsieh, M.C.2    Wang, C.Y.3
  • 6
    • 84925884366 scopus 로고    scopus 로고
    • The role of statins in the treatment of type 2 diabetes mellitus: An update
    • Katsiki N, Athyros VG, Karagiannis A, et al. The role of statins in the treatment of type 2 diabetes mellitus: An update. Curr Pharm Des 2014;20:3665-74
    • (2014) Curr Pharm des , vol.20 , pp. 3665-3674
    • Katsiki, N.1    Athyros, V.G.2    Karagiannis, A.3
  • 7
    • 78651085122 scopus 로고    scopus 로고
    • Do statins beneficially or adversely affect glucose homeostasis?
    • Kostapanos MS, Liamis GL, Milionis HJ, et al. Do statins beneficially or adversely affect glucose homeostasis? Curr Vasc Pharmacol 2010;8:612-31
    • (2011) Curr Vasc Pharmacol , vol.8 , pp. 612-631
    • Kostapanos, M.S.1    Liamis, G.L.2    Milionis, H.J.3
  • 8
    • 84923653355 scopus 로고    scopus 로고
    • New-onset diabetes and statins: Throw the bath water out, but, please, keep the baby!
    • Katsiki N, Rizzo M, Mikhailidis DP, et al. New-onset diabetes and statins: throw the bath water out, but, please, keep the baby!. Metabolism 2015;64:471-5
    • (2015) Metabolism , vol.64 , pp. 471-475
    • Katsiki, N.1    Rizzo, M.2    Mikhailidis, D.P.3
  • 10
    • 84864861863 scopus 로고    scopus 로고
    • Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: An analysis from the JUPITER trial
    • Ridker PM, Pradhan A, MacFadyen JG, et al. Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: An analysis from the JUPITER trial. Lancet 2012;380:565-71
    • (2012) Lancet , vol.380 , pp. 565-571
    • Ridker, P.M.1    Pradhan, A.2    MacFadyen, J.G.3
  • 11
    • 84861869259 scopus 로고    scopus 로고
    • Long-term impact of multifactorial treatment on new-onset diabetes and related cardiovascular events in metabolic syndrome: A post hoc ATTEMPT analysis
    • Athyros VG, Elisaf MS, Alexandrides T, et al. Long-term impact of multifactorial treatment on new-onset diabetes and related cardiovascular events in metabolic syndrome: A post hoc ATTEMPT analysis. Angiology 2012;63:358-66
    • (2012) Angiology , vol.63 , pp. 358-366
    • Athyros, V.G.1    Elisaf, M.S.2    Alexandrides, T.3
  • 12
    • 77549087054 scopus 로고    scopus 로고
    • Statins and risk of incident diabetes: A collaborative meta-Analysis of randomised statin trials
    • Sattar N, Preiss D, Murray HM, et al. Statins and risk of incident diabetes: A collaborative meta-Analysis of randomised statin trials. Lancet 2010;375:735-42
    • (2011) Lancet , vol.375 , pp. 735-742
    • Sattar, N.1    Preiss, D.2    Murray, H.M.3
  • 13
    • 84901704225 scopus 로고    scopus 로고
    • Higher potency statins and the risk of new diabetes: Multicentre, observational study of administrative databases
    • Dormuth CR, Filion KB, Paterson JM, et al. Higher potency statins and the risk of new diabetes: multicentre, observational study of administrative databases. BMJ 2014;348:g3244
    • (2014) BMJ , vol.348 , pp. g3244
    • Dormuth, C.R.1    Filion, K.B.2    Paterson, J.M.3
  • 14
    • 68949196883 scopus 로고    scopus 로고
    • Rosuvastatin treatment is associated with an increase in insulin resistance in hyperlipidaemic patients with impaired fasting glucose
    • Kostapanos MS, Milionis HJ, Agouridis AD, et al. Rosuvastatin treatment is associated with an increase in insulin resistance in hyperlipidaemic patients with impaired fasting glucose. Int J Clin Pract 2009;63:1308-13
    • (2009) Int J Clin Pract , vol.63 , pp. 1308-1313
    • Kostapanos, M.S.1    Milionis, H.J.2    Agouridis, A.D.3
  • 16
    • 84875065352 scopus 로고    scopus 로고
    • Statins and risk of treated incident diabetes in a primary care population
    • Zaharan NL, Williams D, Bennett K. Statins and risk of treated incident diabetes in a primary care population. Br J Clin Pharmacol 2013;75:1118-24
    • (2013) Br J Clin Pharmacol , vol.75 , pp. 1118-1124
    • Zaharan, N.L.1    Williams, D.2    Bennett, K.3
  • 17
    • 84939969799 scopus 로고    scopus 로고
    • Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: A 6 year follow-up study of the METSIM cohort
    • Cederberg H, Stancakova A, Yaluri N, et al. Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: A 6 year follow-up study of the METSIM cohort. Diabetologia 2015;58:1109-17
    • (2015) Diabetologia , vol.58 , pp. 1109-1117
    • Cederberg, H.1    Stancakova, A.2    Yaluri, N.3
  • 18
    • 84937525521 scopus 로고    scopus 로고
    • Variable effects of statins on glucose homeostasis parameters and their diabetogenic role. Reply to Kostapanos MS Agouridis AP and Elisaf MS [letter]
    • Cederberg H, Laakso M. Variable effects of statins on glucose homeostasis parameters and their diabetogenic role. Reply to Kostapanos MS, Agouridis AP and Elisaf MS [letter]. Diabetologia 2015;58:1962-3
    • (2015) Diabetologia , vol.58 , pp. 1962-1963
    • Cederberg, H.1    Laakso, M.2
  • 19
    • 84937513706 scopus 로고    scopus 로고
    • Variable effects of statins on glucose homeostasis parameters and their diabetogenic role
    • Kostapanos MS, Agouridis AP, Elisaf MS. Variable effects of statins on glucose homeostasis parameters and their diabetogenic role. Diabetologia 2015;58:1960-1
    • (2015) Diabetologia , vol.58 , pp. 1960-1961
    • Kostapanos, M.S.1    Agouridis, A.P.2    Elisaf, M.S.3
  • 20
    • 73749087527 scopus 로고    scopus 로고
    • Differing effect of statins on insulin sensitivity in non-diabetics: A systematic review and meta-Analysis
    • Baker WL, Talati R, White CM, et al. Differing effect of statins on insulin sensitivity in non-diabetics: A systematic review and meta-Analysis. Diabetes Res Clin Pract 2010;87:98-107
    • (2011) Diabetes Res Clin Pract , vol.87 , pp. 98-107
    • Baker, W.L.1    Talati, R.2    White, C.M.3
  • 21
    • 84912127068 scopus 로고    scopus 로고
    • Safety profile of subjects treated to very low low-density lipoprotein cholesterol levels (30 mg/dl) with rosuvastatin 20 mg daily (from JUPITER
    • Everett BM, Mora S, Glynn RJ, et al. Safety profile of subjects treated to very low low-density lipoprotein cholesterol levels (30 mg/dl) with rosuvastatin 20 mg daily (from JUPITER). Am J Cardiol 2014;114:1682-9
    • (2014) Am J Cardiol , vol.114 , pp. 1682-1689
    • Everett, B.M.1    Mora, S.2    Glynn, R.J.3
  • 22
    • 84899911844 scopus 로고    scopus 로고
    • Effect of change in body weight on incident diabetes mellitus in patients with stable coronary artery disease treated with atorvastatin (from the treating to new targets study
    • Ong KL, Waters DD, Messig M, et al. Effect of change in body weight on incident diabetes mellitus in patients with stable coronary artery disease treated with atorvastatin (from the treating to new targets study). Am J Cardiol 2014;113:1593-8
    • (2014) Am J Cardiol , vol.113 , pp. 1593-1598
    • Ong, K.L.1    Waters, D.D.2    Messig, M.3
  • 23
    • 84878773567 scopus 로고    scopus 로고
    • Risk of incident diabetes among patients treated with statins: Population based study
    • Carter AA, Gomes T, Camacho X, et al. Risk of incident diabetes among patients treated with statins: population based study. BMJ 2013;346:f2610
    • (2013) BMJ , vol.346 , pp. f2610
    • Carter, A.A.1    Gomes, T.2    Camacho, X.3
  • 24
    • 84866733914 scopus 로고    scopus 로고
    • Statins, risk of diabetes, and implications on outcomes in the general population
    • Wang KL, Liu CJ, Chao TF, et al. Statins, risk of diabetes, and implications on outcomes in the general population. J Am Coll Cardiol 2012;60:1231-8
    • (2012) J Am Coll Cardiol , vol.60 , pp. 1231-1238
    • Wang, K.L.1    Liu, C.J.2    Chao, T.F.3
  • 25
    • 33344471035 scopus 로고    scopus 로고
    • Effect of pravastatin and atorvastatin on glucose metabolism in nondiabetic patients with hypercholesterolemia
    • Ishikawa M, Namiki A, Kubota T, et al. Effect of pravastatin and atorvastatin on glucose metabolism in nondiabetic patients with hypercholesterolemia. Intern Med 2006;45:51-5
    • (2006) Intern Med , vol.45 , pp. 51-55
    • Ishikawa, M.1    Namiki, A.2    Kubota, T.3
  • 26
    • 80054712207 scopus 로고    scopus 로고
    • Comparison of the effects of simvastatin vs rosuvastatin vs simvastatin/ezetimibe on parameters of insulin resistance
    • Moutzouri E, Liberopoulos E, Mikhailidis DP, et al. Comparison of the effects of simvastatin vs rosuvastatin vs simvastatin/ezetimibe on parameters of insulin resistance. Int J Clin Pract 2011;65:1141-8
    • (2011) Int J Clin Pract , vol.65 , pp. 1141-1148
    • Moutzouri, E.1    Liberopoulos, E.2    Mikhailidis, D.P.3
  • 28
    • 33846604584 scopus 로고    scopus 로고
    • Statins and risk of cancer: A systematic review and metaanalysis
    • Browning DR, Martin RM. Statins and risk of cancer: A systematic review and metaanalysis. Int J Cancer 2007;120:833-43
    • (2007) Int J Cancer , vol.120 , pp. 833-843
    • Browning, D.R.1    Martin, R.M.2
  • 29
    • 84936817948 scopus 로고    scopus 로고
    • Effect of pitavastatin on glucose HbA1c and incident diabetes: A meta-Analysis of randomized controlled clinical trials in individuals without diabetes
    • Vallejo-Vaz AJ, Kondapally Seshasai SR, Kurogi K, et al. Effect of pitavastatin on glucose, HbA1c and incident diabetes: A meta-Analysis of randomized controlled clinical trials in individuals without diabetes. Atherosclerosis 2015;241:409-18
    • (2015) Atherosclerosis , vol.241 , pp. 409-418
    • Vallejo-Vaz, A.J.1    Kondapally Seshasai, S.R.2    Kurogi, K.3
  • 30
    • 84904086869 scopus 로고    scopus 로고
    • Statins and the risk of type 2 diabetes mellitus: Cohort study using the UK clinical practice pesearch datalink
    • Macedo AF, Douglas I, Smeeth L, et al. Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink. BMC Cardiovasc Disord 2014;14:85
    • (2014) BMC Cardiovasc Disord , vol.14 , pp. 85
    • Macedo, A.F.1    Douglas, I.2    Smeeth, L.3
  • 31
    • 79959428660 scopus 로고    scopus 로고
    • Risk of incident diabetes with intensivedose compared with moderate-dose statin therapy: A meta-Analysis
    • Preiss D, Seshasai SR, Welsh P, et al. Risk of incident diabetes with intensivedose compared with moderate-dose statin therapy: A meta-Analysis. JAMA 2011;305:2556-64
    • (2011) JAMA , vol.305 , pp. 2556-2564
    • Preiss, D.1    Seshasai, S.R.2    Welsh, P.3
  • 32
    • 84862908066 scopus 로고    scopus 로고
    • Statin use and risk of diabetes mellitus in postmenopausal women in the Womens Health Initiative
    • Culver AL, Ockene IS, Balasubramanian R, et al. Statin use and risk of diabetes mellitus in postmenopausal women in the Womens Health Initiative. Arch Intern Med 2012;172:144-52
    • (2012) Arch Intern Med , vol.172 , pp. 144-152
    • Culver, A.L.1    Ockene, I.S.2    Balasubramanian, R.3
  • 33
    • 70349664292 scopus 로고    scopus 로고
    • Statin therapy and risk of developing type 2 diabetes: A meta-Analysis
    • Rajpathak SN, Kumbhani DJ, Crandall J, et al. Statin therapy and risk of developing type 2 diabetes: A meta-Analysis. Diabetes Care 2009;32:1924-9
    • (2009) Diabetes Care , vol.32 , pp. 1924-1929
    • Rajpathak, S.N.1    Kumbhani, D.J.2    Crandall, J.3
  • 34
    • 84924358878 scopus 로고    scopus 로고
    • Association between familial hypercholesterolemia and prevalence of type 2 diabetes mellitus
    • Besseling J, Kastelein JJ, Defesche JC, et al. Association between familial hypercholesterolemia and prevalence of type 2 diabetes mellitus. JAMA 2015;313:1029-36
    • (2015) JAMA , vol.313 , pp. 1029-1036
    • Besseling, J.1    Kastelein, J.J.2    Defesche, J.C.3
  • 36
    • 77952401289 scopus 로고    scopus 로고
    • HDL and LDL cholesterol significantly influence beta-cell function in type 2 diabetes mellitus
    • Kruit JK, Brunham LR, Verchere CB, et al. HDL and LDL cholesterol significantly influence beta-cell function in type 2 diabetes mellitus. Curr Opin Lipidol 2010;21:178-85
    • (2011) Curr Opin Lipidol , vol.21 , pp. 178-185
    • Kruit, J.K.1    Brunham, L.R.2    Verchere, C.B.3
  • 37
    • 0032978644 scopus 로고    scopus 로고
    • Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet beta-cells
    • Yada T, Nakata M, Shiraishi T, et al. Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet beta-cells. Br J Pharmacol 1999;126:1205-13
    • (1999) Br J Pharmacol , vol.126 , pp. 1205-1213
    • Yada, T.1    Nakata, M.2    Shiraishi, T.3
  • 38
    • 53249121824 scopus 로고    scopus 로고
    • Inhibition of cholesterol biosynthesis impairs insulin secretion and voltage-gated calcium channel function in pancreatic beta-cells
    • Xia F, Xie L, Mihic A, et al. Inhibition of cholesterol biosynthesis impairs insulin secretion and voltage-gated calcium channel function in pancreatic beta-cells. Endocrinology 2008;149:5136-45
    • (2008) Endocrinology , vol.149 , pp. 5136-5145
    • Xia, F.1    Xie, L.2    Mihic, A.3
  • 39
    • 38849189665 scopus 로고    scopus 로고
    • Distinct effects of pravastatin, atorvastatin, and simvastatin on insulin secretion from a beta-cell line, MIN6 cells
    • Ishikawa M, Okajima F, Inoue N, et al. Distinct effects of pravastatin, atorvastatin, and simvastatin on insulin secretion from a beta-cell line, MIN6 cells. J Atheroscler Thromb 2006;13:329-35
    • (2006) J Atheroscler Thromb , vol.13 , pp. 329-335
    • Ishikawa, M.1    Okajima, F.2    Inoue, N.3
  • 40
    • 84903625140 scopus 로고    scopus 로고
    • Effects of simvastatin on glucose metabolism in mouse MIN6 cells
    • Zhou J, Li W, Xie Q, et al. Effects of simvastatin on glucose metabolism in mouse MIN6 cells. J Diabetes Res 2014;2014:376570
    • (2014) J Diabetes Res , vol.2014 , pp. 376570
    • Zhou, J.1    Li, W.2    Xie, Q.3
  • 41
    • 84890549094 scopus 로고    scopus 로고
    • Direct effects of rosuvastatin on pancreatic human beta cells
    • Bugliani M, Syed F, Masini M, et al. Direct effects of rosuvastatin on pancreatic human beta cells. Acta Diabetol 2013;50:983-5
    • (2013) Acta Diabetol , vol.50 , pp. 983-985
    • Bugliani, M.1    Syed, F.2    Masini, M.3
  • 42
    • 77957254197 scopus 로고    scopus 로고
    • Cholesterol biosynthesis pathway intermediates and inhibitors regulate glucose-stimulated insulin secretion and secretory granule formation in pancreatic beta-cells
    • Tsuchiya M, Hosaka M, Moriguchi T, et al. Cholesterol biosynthesis pathway intermediates and inhibitors regulate glucose-stimulated insulin secretion and secretory granule formation in pancreatic beta-cells. Endocrinology 2010;151:4705-16
    • (2011) Endocrinology , vol.151 , pp. 4705-4716
    • Tsuchiya, M.1    Hosaka, M.2    Moriguchi, T.3
  • 43
    • 34548386258 scopus 로고    scopus 로고
    • Direct effect of cholesterol on insulin secretion: A novel mechanism for pancreatic beta-cell dysfunction
    • Hao M, Head WS, Gunawardana SC, et al. Direct effect of cholesterol on insulin secretion: A novel mechanism for pancreatic beta-cell dysfunction. Diabetes 2007;56:2328-38
    • (2007) Diabetes , vol.56 , pp. 2328-2338
    • Hao, M.1    Head, W.S.2    Gunawardana, S.C.3
  • 44
    • 77952090218 scopus 로고    scopus 로고
    • Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice
    • Kruit JK, Kremer PH, Dai L, et al. Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice. Diabetologia 2010;53:1110-19
    • (2011) Diabetologia , vol.53 , pp. 1110-1119
    • Kruit, J.K.1    Kremer, P.H.2    Dai, L.3
  • 45
    • 84892187236 scopus 로고    scopus 로고
    • Diabetogenic effect of statins: A double-edged sword?
    • Yoon JS, Lee HW. Diabetogenic effect of statins: A double-edged sword? Diabetes Metab J 2013;37:415-22
    • (2013) Diabetes Metab J , vol.37 , pp. 415-422
    • Yoon, J.S.1    Lee, H.W.2
  • 46
    • 33644688772 scopus 로고    scopus 로고
    • Diabetes and insulin secretion: The ATPsensitive K+ channel (K ATP) connection
    • Koster JC, Permutt MA, Nichols CG. Diabetes and insulin secretion: the ATPsensitive K+ channel (K ATP) connection. Diabetes 2005;54:3065-72
    • (2005) Diabetes , vol.54 , pp. 3065-3072
    • Koster, J.C.1    Permutt, M.A.2    Nichols, C.G.3
  • 47
    • 0036786434 scopus 로고    scopus 로고
    • Inhibition of glucose-And calciuminduced insulin secretion from betaTC3 cells by novel inhibitors of protein isoprenylation
    • Amin R, Chen HQ, Tannous M, et al. Inhibition of glucose-And calciuminduced insulin secretion from betaTC3 cells by novel inhibitors of protein isoprenylation. J Pharmacol Exp Ther 2002;303:82-8
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 82-88
    • Amin, R.1    Chen, H.Q.2    Tannous, M.3
  • 48
    • 0027613827 scopus 로고
    • Viscoelasticity of BLM from choline plasmalogen, alkylacyl-And diacyl-glycerophosphocholines
    • Hianik T, Dlugopolsky J, Masarykova D, et al. Viscoelasticity of BLM from choline plasmalogen, alkylacyl-And diacyl-glycerophosphocholines. Gen Physiol Biophys 1993;12:271-82
    • (1993) Gen Physiol Biophys , vol.12 , pp. 271-282
    • Hianik, T.1    Dlugopolsky, J.2    Masarykova, D.3
  • 49
    • 0035857151 scopus 로고    scopus 로고
    • Diabetes, insulin secretion, and the pancreatic beta-cell mitochondrion
    • Langin D. Diabetes, insulin secretion, and the pancreatic beta-cell mitochondrion. N Engl J Med 2001;345:1772-4
    • (2001) N Engl J Med , vol.345 , pp. 1772-1774
    • Langin, D.1
  • 50
    • 0037077717 scopus 로고    scopus 로고
    • Diabetes and the role of isoprenoid biosynthesis
    • Bliznakov EG. Diabetes and the role of isoprenoid biosynthesis. FEBS Lett 2002;525:169-70
    • (2002) FEBS Lett , vol.525 , pp. 169-170
    • Bliznakov, E.G.1
  • 51
    • 0028062689 scopus 로고
    • Lovastatin disrupts early events in insulin signaling: A potential mechanism of lovastatins anti-mitogenic activity
    • McGuire TF, Xu XQ, Corey SJ, et al. Lovastatin disrupts early events in insulin signaling: A potential mechanism of lovastatins anti-mitogenic activity. Biochem Biophys Res Commun 1994;204:399-406
    • (1994) Biochem Biophys Res Commun , vol.204 , pp. 399-406
    • McGuire, T.F.1    Xu, X.Q.2    Corey, S.J.3
  • 52
    • 0030046472 scopus 로고    scopus 로고
    • Lovastatin inhibits the stimulation of mitogen-Activated protein kinase by insulin in HIRcB fibroblasts
    • Xu XQ, McGuire TF, Blaskovich MA, et al. Lovastatin inhibits the stimulation of mitogen-Activated protein kinase by insulin in HIRcB fibroblasts. Arch Biochem Biophys 1996;326:233-7
    • (1996) Arch Biochem Biophys , vol.326 , pp. 233-237
    • Xu, X.Q.1    McGuire, T.F.2    Blaskovich, M.A.3
  • 53
    • 0033604612 scopus 로고    scopus 로고
    • Insulin signaling regulating the trafficking and plasma membrane fusion of GLUT4-containing intracellular vesicles
    • Elmendorf JS, Pessin JE. Insulin signaling regulating the trafficking and plasma membrane fusion of GLUT4-containing intracellular vesicles. Exp Cell Res 1999;253:55-62
    • (1999) Exp Cell Res , vol.253 , pp. 55-62
    • Elmendorf, J.S.1    Pessin, J.E.2
  • 54
    • 0036434431 scopus 로고    scopus 로고
    • Insulin regulation of glucose uptake: A complex interplay of intracellular signalling pathways
    • Khan AH, Pessin JE. Insulin regulation of glucose uptake: A complex interplay of intracellular signalling pathways. Diabetologia 2002;45:1475-83
    • (2002) Diabetologia , vol.45 , pp. 1475-1483
    • Khan, A.H.1    Pessin, J.E.2
  • 55
    • 33745794259 scopus 로고    scopus 로고
    • Effects of statins on the adipocyte maturation and expression of glucose transporter 4 (SLC2A4): Implications in glycaemic control
    • Nakata M, Nagasaka S, Kusaka I, et al. Effects of statins on the adipocyte maturation and expression of glucose transporter 4 (SLC2A4): implications in glycaemic control. Diabetologia 2006;49:1881-92
    • (2006) Diabetologia , vol.49 , pp. 1881-1892
    • Nakata, M.1    Nagasaka, S.2    Kusaka, I.3
  • 56
    • 0035798232 scopus 로고    scopus 로고
    • Inhibition of isoprenoid biosynthesis causes insulin resistance in 3T3-L1 adipocytes
    • Chamberlain LH. Inhibition of isoprenoid biosynthesis causes insulin resistance in 3T3-L1 adipocytes. FEBS Lett 2001;507:357-61
    • (2001) FEBS Lett , vol.507 , pp. 357-361
    • Chamberlain, L.H.1
  • 57
    • 44349104255 scopus 로고    scopus 로고
    • Effects of atorvastatin and pravastatin on signal transduction related to glucose uptake in 3T3L1 adipocytes
    • Takaguri A, Satoh K, Itagaki M, et al. Effects of atorvastatin and pravastatin on signal transduction related to glucose uptake in 3T3L1 adipocytes. J Pharmacol Sci 2008;107:80-9
    • (2008) J Pharmacol Sci , vol.107 , pp. 80-89
    • Takaguri, A.1    Satoh, K.2    Itagaki, M.3
  • 58
    • 34250630941 scopus 로고    scopus 로고
    • Direct adipotropic actions of atorvastatin: Differentiation state-dependent induction of apoptosis, modulation of endocrine function, and inhibition of glucose uptake
    • Mauser W, Perwitz N, Meier B, et al. Direct adipotropic actions of atorvastatin: differentiation state-dependent induction of apoptosis, modulation of endocrine function, and inhibition of glucose uptake. Eur J Pharmacol 2007;564:37-46
    • (2007) Eur J Pharmacol , vol.564 , pp. 37-46
    • Mauser, W.1    Perwitz, N.2    Meier, B.3
  • 59
    • 77956226709 scopus 로고    scopus 로고
    • Beneficial direct adipotropic actions of pitavastatin in vitro and their manifestations in obese mice
    • Ishihara Y, Ohmori K, Mizukawa M, et al. Beneficial direct adipotropic actions of pitavastatin in vitro and their manifestations in obese mice. Atherosclerosis 2010;212:131-8
    • (2011) Atherosclerosis , vol.212 , pp. 131-138
    • Ishihara, Y.1    Ohmori, K.2    Mizukawa, M.3
  • 60
    • 84899092930 scopus 로고    scopus 로고
    • Effect of high-dose pitavastatin on glucose homeostasis in patients at elevated risk of new-onset diabetes: Insights from the CAPITAIN and PREVAIL-US studies
    • Chapman MJ, Orsoni A, Robillard P, et al. Effect of high-dose pitavastatin on glucose homeostasis in patients at elevated risk of new-onset diabetes: insights from the CAPITAIN and PREVAIL-US studies. Curr Med Res Opin 2014;30:775-84
    • (2014) Curr Med Res Opin , vol.30 , pp. 775-784
    • Chapman, M.J.1    Orsoni, A.2    Robillard, P.3
  • 62
    • 84908651413 scopus 로고    scopus 로고
    • Statin-induced insulin resistance through inflammasome activation: Sailing between Scylla and Charybdis
    • Mitchell P, Marette A. Statin-induced insulin resistance through inflammasome activation: sailing between Scylla and Charybdis. Diabetes 2014;63:3569-71
    • (2014) Diabetes , vol.63 , pp. 3569-3571
    • Mitchell, P.1    Marette, A.2
  • 63
    • 79955038882 scopus 로고    scopus 로고
    • Fatty acidinduced NLRP3-ASC inflammasome activation interferes with insulin signaling
    • Wen H, Gris D, Lei Y, et al. Fatty acidinduced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol 2011;12:408-15
    • (2011) Nat Immunol , vol.12 , pp. 408-415
    • Wen, H.1    Gris, D.2    Lei, Y.3
  • 64
    • 84906870036 scopus 로고    scopus 로고
    • Fluvastatin causes NLRP3 inflammasome-mediated adipose insulin resistance
    • Henriksbo BD, Lau TC, Cavallari JF, et al. Fluvastatin causes NLRP3 inflammasome-mediated adipose insulin resistance. Diabetes 2014;63:3742-7
    • (2014) Diabetes , vol.63 , pp. 3742-3747
    • Henriksbo, B.D.1    Lau, T.C.2    Cavallari, J.F.3
  • 65
    • 84872018875 scopus 로고    scopus 로고
    • Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes
    • Lee HM, Kim JJ, Kim HJ, et al. Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes. Diabetes 2013;62:194-204
    • (2013) Diabetes , vol.62 , pp. 194-204
    • Lee, H.M.1    Kim, J.J.2    Kim, H.J.3
  • 66
    • 84885863093 scopus 로고    scopus 로고
    • Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue
    • Esser N, LHomme L, De Roover A, et al. Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue. Diabetologia 2013;56:2487-97
    • (2013) Diabetologia , vol.56 , pp. 2487-2497
    • Esser, N.1    Lhomme, L.2    De Roover, A.3
  • 67
    • 84860781238 scopus 로고    scopus 로고
    • Statins is it really time to reassess benefits and risks?
    • Goldfine AB. Statins: is it really time to reassess benefits and risks? N Engl J Med 2012;366:1752-5
    • (2012) N Engl J Med , vol.366 , pp. 1752-1755
    • Goldfine, A.B.1
  • 68
    • 84867178512 scopus 로고    scopus 로고
    • PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance
    • Gupta A, Dey CS. PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance. Mol Biol Cell 2012;23:3882-98
    • (2012) Mol Biol Cell , vol.23 , pp. 3882-3898
    • Gupta, A.1    Dey, C.S.2
  • 69
    • 84930737140 scopus 로고    scopus 로고
    • PTEN upregulation may explain the development of insulin resistance and type 2 diabetes with high dose statins
    • Birnbaum Y, Nanhwan MK, Ling S, et al. PTEN upregulation may explain the development of insulin resistance and type 2 diabetes with high dose statins. Cardiovasc Drugs Ther 2014;28:447-57
    • (2014) Cardiovasc Drugs Ther , vol.28 , pp. 447-457
    • Birnbaum, Y.1    Nanhwan, M.K.2    Ling, S.3
  • 70
    • 84920747555 scopus 로고    scopus 로고
    • Could changes in adiponectin drive the effect of statins on the risk of new-onset diabetes? the case of pitavastatin
    • Arnaboldi L, Corsini A. Could changes in adiponectin drive the effect of statins on the risk of new-onset diabetes? The case of pitavastatin. Atheroscler Suppl 2015;16:1-27
    • (2015) Atheroscler Suppl , vol.16 , pp. 1-27
    • Arnaboldi, L.1    Corsini, A.2
  • 71
    • 67650169799 scopus 로고    scopus 로고
    • Adiponectin levels and risk of type 2 diabetes: A systematic review and meta-Analysis
    • Li S, Shin HJ, Ding EL, et al. Adiponectin levels and risk of type 2 diabetes: A systematic review and meta-Analysis. JAMA 2009;302:179-88
    • (2009) JAMA , vol.302 , pp. 179-188
    • Li, S.1    Shin, H.J.2    Ding, E.L.3
  • 72
    • 84921493092 scopus 로고    scopus 로고
    • HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials
    • Swerdlow DI, Preiss D, Kuchenbaecker KB, et al. HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet 2015;385:351-61
    • (2015) Lancet , vol.385 , pp. 351-361
    • Swerdlow, D.I.1    Preiss, D.2    Kuchenbaecker, K.B.3
  • 74
    • 84904497873 scopus 로고    scopus 로고
    • Non-cardiovascular effects associated with statins
    • Desai CS, Martin SS, Blumenthal RS. Non-cardiovascular effects associated with statins. BMJ 2014;349:g3743
    • (2014) BMJ , vol.349 , pp. g3743
    • Desai, C.S.1    Martin, S.S.2    Blumenthal, R.S.3
  • 75
    • 84899150858 scopus 로고    scopus 로고
    • Unintended effects of statins from observational studies in the general population: Systematic review and meta-Analysis
    • Macedo AF, Taylor FC, Casas JP, et al. Unintended effects of statins from observational studies in the general population: systematic review and meta-Analysis. BMC Med 2014;12:51
    • (2014) BMC Med , vol.12 , pp. 51
    • Macedo, A.F.1    Taylor, F.C.2    Casas, J.P.3
  • 76
    • 84892374541 scopus 로고    scopus 로고
    • Efficacy and safety evaluation of intensive statin therapy in older patients with coronary heart disease: A systematic review and meta-Analysis
    • Yan YL, Qiu B, Hu LJ, et al. Efficacy and safety evaluation of intensive statin therapy in older patients with coronary heart disease: A systematic review and meta-Analysis. Eur J Clin Pharmacol 2013;69:2001-9
    • (2013) Eur J Clin Pharmacol , vol.69 , pp. 2001-2009
    • Yan, Y.L.1    Qiu, B.2    Hu, L.J.3
  • 77
    • 84921493092 scopus 로고    scopus 로고
    • HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials
    • Swerdlow DI, Preiss D, Kuchenbaecker KB, et al. HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet 2015;385(9965):351-61
    • (2015) Lancet , vol.385 , Issue.9965 , pp. 351-361
    • Swerdlow, D.I.1    Preiss, D.2    Kuchenbaecker, K.B.3
  • 78
    • 84902008064 scopus 로고    scopus 로고
    • Different time trends of caloric and fat intake between statin users and nonusers among US adults: Gluttony in the time of statins?
    • Sugiyama T, Tsugawa Y, Tseng CH, et al. Different time trends of caloric and fat intake between statin users and nonusers among US adults: gluttony in the time of statins? JAMA Intern Med 2014;174:1038-45
    • (2014) JAMA Intern Med , vol.174 , pp. 1038-1045
    • Sugiyama, T.1    Tsugawa, Y.2    Tseng, C.H.3
  • 79
    • 84900802536 scopus 로고    scopus 로고
    • The use of statins in people at risk of developing diabetes mellitus: Evidence and guidance for clinical practice
    • Sattar NA, Ginsberg H, Ray K, et al. The use of statins in people at risk of developing diabetes mellitus: evidence and guidance for clinical practice. Atheroscler Suppl 2014;15:1-15
    • (2014) Atheroscler Suppl , vol.15 , pp. 1-15
    • Sattar, N.A.1    Ginsberg, H.2    Ray, K.3
  • 81
    • 84931411520 scopus 로고    scopus 로고
    • Ezetimibe added to statin therapy after acute coronary Syndromes
    • Cannon CP, Blazing MA, Giugliano RP, et al. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. N Engl J Med 2015;372:2387-97
    • (2015) N Engl J Med , vol.372 , pp. 2387-2397
    • Cannon, C.P.1    Blazing, M.A.2    Giugliano, R.P.3
  • 82
    • 84924598588 scopus 로고    scopus 로고
    • Should we consider ezetimibe to reach even lower LDL-C targets?
    • Agouridis AP, Mikhailidis DP. Should we consider ezetimibe to reach even lower LDL-C targets? Curr Med Res Opin 2015;31:459-60
    • (2015) Curr Med Res Opin , vol.31 , pp. 459-460
    • Agouridis, A.P.1    Mikhailidis, D.P.2
  • 83
    • 34548125027 scopus 로고    scopus 로고
    • Meta-Analysis of the cholesterol-lowering effect of ezetimibe added to ongoing statin therapy
    • Mikhailidis DP, Sibbring GC, Ballantyne CM, et al. Meta-Analysis of the cholesterol-lowering effect of ezetimibe added to ongoing statin therapy. Curr Med Res Opin 2007;23:2009-26
    • (2007) Curr Med Res Opin , vol.23 , pp. 2009-2026
    • Mikhailidis, D.P.1    Sibbring, G.C.2    Ballantyne, C.M.3
  • 84
    • 79956099377 scopus 로고    scopus 로고
    • Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: Systematic review and meta-Analysis
    • Mikhailidis DP, Lawson RW, McCormick AL, et al. Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: systematic review and meta-Analysis. Curr Med Res Opin 2011;27:1191-210
    • (2011) Curr Med Res Opin , vol.27 , pp. 1191-1210
    • Mikhailidis, D.P.1    Lawson, R.W.2    McCormick, A.L.3
  • 85
    • 38849104344 scopus 로고    scopus 로고
    • Effectiveness of ezetimibe alone or in combination with twice a week Atorvastatin (10 mg) for statin intolerant high-risk patients
    • Athyros VG, Tziomalos K, Kakafika AI, et al. Effectiveness of ezetimibe alone or in combination with twice a week Atorvastatin (10 mg) for statin intolerant high-risk patients. Am J Cardiol 2008;101:483-5
    • (2008) Am J Cardiol , vol.101 , pp. 483-485
    • Athyros, V.G.1    Tziomalos, K.2    Kakafika, A.I.3
  • 87
    • 84920955133 scopus 로고    scopus 로고
    • Proprotein convertase subtilisin kexin 9 inhibitors: Next generation in lipidlowering therapy
    • Milionis H, Liamis G, Elisaf M. Proprotein convertase subtilisin kexin 9 inhibitors: next generation in lipidlowering therapy. Expert Opin Biol Ther 2015;15:287-98
    • (2015) Expert Opin Biol Ther , vol.15 , pp. 287-298
    • Milionis, H.1    Liamis, G.2    Elisaf, M.3
  • 88
    • 84940332992 scopus 로고    scopus 로고
    • Management of hypercholesterolemia for prevention of atherosclerotic cardiovascular disease: Focus on the potential role of recombinant anti-PCSK9 monoclonal antibodies
    • quiz
    • Verma DR, Brinton EA. Management of hypercholesterolemia for prevention of atherosclerotic cardiovascular disease: focus on the potential role of recombinant anti-PCSK9 monoclonal antibodies. Rev Cardiovasc Med 2014;15:86-101.quiz
    • (2014) Rev Cardiovasc Med , vol.15 , pp. 86-101
    • Verma, D.R.1    Brinton, E.A.2
  • 89
    • 84925351969 scopus 로고    scopus 로고
    • Lipid lowering with PCSK9 inhibitors
    • Dadu RT, Ballantyne CM. Lipid lowering with PCSK9 inhibitors. Nat Rev Cardiol 2014;11:563-75
    • (2014) Nat Rev Cardiol , vol.11 , pp. 563-575
    • Dadu, R.T.1    Ballantyne, C.M.2


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