메뉴 건너뛰기




Volumn 56, Issue 9, 2007, Pages 2328-2338

Direct effect of cholesterol on insulin secretion: A novel mechanism for pancreatic β-cell dysfunction

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; FATTY ACID; NITRIC OXIDE SYNTHASE;

EID: 34548386258     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db07-0056     Document Type: Article
Times cited : (272)

References (50)
  • 1
    • 0028063888 scopus 로고
    • Pathogenesis of non-insulin-dependent diabetes mellitus
    • Yki-Jarvinen H: Pathogenesis of non-insulin-dependent diabetes mellitus. Lancet 343:91-95, 1994
    • (1994) Lancet , vol.343 , pp. 91-95
    • Yki-Jarvinen, H.1
  • 2
    • 0037283601 scopus 로고    scopus 로고
    • The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes
    • Kahn SE: The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia 46:3-19, 2003
    • (2003) Diabetologia , vol.46 , pp. 3-19
    • Kahn, S.E.1
  • 4
    • 0029151863 scopus 로고
    • Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: Genetic and clinical implications
    • Unger RH: Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: genetic and clinical implications. Diabetes 44:863-870, 1995
    • (1995) Diabetes , vol.44 , pp. 863-870
    • Unger, R.H.1
  • 5
    • 0142093526 scopus 로고    scopus 로고
    • Fatty acid metabolism and insulin secretion in pancreatic beta cells
    • Yaney GC, Corkey BE: Fatty acid metabolism and insulin secretion in pancreatic beta cells. Diabetologia 46:1297-1312, 2003
    • (2003) Diabetologia , vol.46 , pp. 1297-1312
    • Yaney, G.C.1    Corkey, B.E.2
  • 6
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown MS, Goldstein JL: The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89:331-340, 1997
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 7
    • 0035907394 scopus 로고    scopus 로고
    • Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes
    • Le Lay S, Krief S, Farnier C, Lefrere I, Le Liepvre X, Bazin R, Ferre P, Dugail I: Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes. J Biol Chem 276:16904-16910, 2001
    • (2001) J Biol Chem , vol.276 , pp. 16904-16910
    • Le Lay, S.1    Krief, S.2    Farnier, C.3    Lefrere, I.4    Le Liepvre, X.5    Bazin, R.6    Ferre, P.7    Dugail, I.8
  • 8
    • 0027156128 scopus 로고
    • Determination of plasma membrane lipid mass and composition in cultured Chinese hamster ovary cells using high gradient magnetic affinity chromatography
    • Warnock DE, Roberts C, Lutz MS, Blackburn WA, Young WW Jr, Baenziger JU: Determination of plasma membrane lipid mass and composition in cultured Chinese hamster ovary cells using high gradient magnetic affinity chromatography. J Biol Chem 268:10145-10153, 1993
    • (1993) J Biol Chem , vol.268 , pp. 10145-10153
    • Warnock, D.E.1    Roberts, C.2    Lutz, M.S.3    Blackburn, W.A.4    Young Jr, W.W.5    Baenziger, J.U.6
  • 9
    • 0037016677 scopus 로고    scopus 로고
    • Vesicular and non-vesicular sterol transport in living cells: The endocytic recycling compartment is a major sterol storage organelle
    • Hao M, Lin SX, Karylowski OJ, Wustner D, McGraw TE, Maxfield FR: Vesicular and non-vesicular sterol transport in living cells: the endocytic recycling compartment is a major sterol storage organelle. J Biol Chem 277:609-617, 2002
    • (2002) J Biol Chem , vol.277 , pp. 609-617
    • Hao, M.1    Lin, S.X.2    Karylowski, O.J.3    Wustner, D.4    McGraw, T.E.5    Maxfield, F.R.6
  • 10
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons K, Ikonen E: Functional rafts in cell membranes. Nature 387:569-572, 1997
    • (1997) Nature , vol.387 , pp. 569-572
    • Simons, K.1    Ikonen, E.2
  • 11
    • 0034625373 scopus 로고    scopus 로고
    • Structure and function of sphingolipid- and cholesterol-rich membrane rafts
    • Brown DA, London E: Structure and function of sphingolipid- and cholesterol-rich membrane rafts. J Biol Chem 275:17221-17224, 2000
    • (2000) J Biol Chem , vol.275 , pp. 17221-17224
    • Brown, D.A.1    London, E.2
  • 12
    • 0034620610 scopus 로고    scopus 로고
    • The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation
    • Xu X, London E: The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation. Biochemistry 39:843-849, 2000
    • (2000) Biochemistry , vol.39 , pp. 843-849
    • Xu, X.1    London, E.2
  • 15
    • 24144484618 scopus 로고    scopus 로고
    • Essential role for membrane lipid rafts in interleukin-1β-induced nitric oxide release from insulin-secreting cells: Potential regulation by caveolin-1+
    • Veluthakal R, Chvyrkova I, Tannous M, McDonald P, Amin R, Hadden T, Thurmond DC, Quon MJ, Kowluru A: Essential role for membrane lipid rafts in interleukin-1β-induced nitric oxide release from insulin-secreting cells: potential regulation by caveolin-1+. Diabetes 54:2576 -2585, 2005
    • (2005) Diabetes , vol.54 , pp. 2576-2585
    • Veluthakal, R.1    Chvyrkova, I.2    Tannous, M.3    McDonald, P.4    Amin, R.5    Hadden, T.6    Thurmond, D.C.7    Quon, M.J.8    Kowluru, A.9
  • 17
    • 30544451865 scopus 로고    scopus 로고
    • Regulation of two insulin granule populations within the reserve pool by distinct calcium sources
    • Hao M, Li X, Rizzo MA, Rocheleau JV, Dawant BM, Piston DW: Regulation of two insulin granule populations within the reserve pool by distinct calcium sources. J Cell Sci 118:5873-5884, 2005
    • (2005) J Cell Sci , vol.118 , pp. 5873-5884
    • Hao, M.1    Li, X.2    Rizzo, M.A.3    Rocheleau, J.V.4    Dawant, B.M.5    Piston, D.W.6
  • 18
    • 0034006587 scopus 로고    scopus 로고
    • Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion
    • Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB: Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion. Diabetes 49:424-430, 2000
    • (2000) Diabetes , vol.49 , pp. 424-430
    • Hohmeier, H.E.1    Mulder, H.2    Chen, G.3    Henkel-Rieger, R.4    Prentki, M.5    Newgard, C.B.6
  • 19
    • 33745313029 scopus 로고    scopus 로고
    • Mechanisms of time-dependent potentiation of insulin release: Involvement of nitric oxide synthase
    • Gunawardana SC, Rocheleau JV, Head WS, Piston DW: Mechanisms of time-dependent potentiation of insulin release: involvement of nitric oxide synthase. Diabetes 55:1029-1033, 2006
    • (2006) Diabetes , vol.55 , pp. 1029-1033
    • Gunawardana, S.C.1    Rocheleau, J.V.2    Head, W.S.3    Piston, D.W.4
  • 20
    • 0032541423 scopus 로고    scopus 로고
    • Cholesterol-dependent retention of GPI-anchored proteins in endosomes
    • Mayor S, Sabharanjak S, Maxfield FR: Cholesterol-dependent retention of GPI-anchored proteins in endosomes. Embo J 17:4626-4638, 1998
    • (1998) Embo J , vol.17 , pp. 4626-4638
    • Mayor, S.1    Sabharanjak, S.2    Maxfield, F.R.3
  • 21
    • 0022538809 scopus 로고
    • The purification and characterization of glucokinase from the thermophile Bacillus stearothermophilus
    • Goward CR, Hartwell R, Atkinson T, Scawen MD: The purification and characterization of glucokinase from the thermophile Bacillus stearothermophilus. Biochem J 237:415-420, 1986
    • (1986) Biochem J , vol.237 , pp. 415-420
    • Goward, C.R.1    Hartwell, R.2    Atkinson, T.3    Scawen, M.D.4
  • 22
    • 0037072825 scopus 로고    scopus 로고
    • A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin
    • Rizzo MA, Magnuson MA, Drain PF, Piston DW: A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin. J Biol Chem 277:34168-34175, 2002
    • (2002) J Biol Chem , vol.277 , pp. 34168-34175
    • Rizzo, M.A.1    Magnuson, M.A.2    Drain, P.F.3    Piston, D.W.4
  • 24
    • 0025374590 scopus 로고
    • Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells
    • D'Ambra R, Surana M, Efrat S, Starr RG, Fleischer N: Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells. Endocrinology 126:2815-2822, 1990
    • (1990) Endocrinology , vol.126 , pp. 2815-2822
    • D'Ambra, R.1    Surana, M.2    Efrat, S.3    Starr, R.G.4    Fleischer, N.5
  • 25
    • 0037028562 scopus 로고    scopus 로고
    • Detection and imaging of zinc secretion from pancreatic beta-cells using a new fluorescent zinc indicator
    • Gee KR, Zhou ZL, Qian WJ, Kennedy R: Detection and imaging of zinc secretion from pancreatic beta-cells using a new fluorescent zinc indicator. J Am Chem Soc 124:776-778, 2002
    • (2002) J Am Chem Soc , vol.124 , pp. 776-778
    • Gee, K.R.1    Zhou, Z.L.2    Qian, W.J.3    Kennedy, R.4
  • 26
    • 0030020423 scopus 로고    scopus 로고
    • Quantitative subcellular imaging of glucose metabolism within intact pancreatic islets
    • Bennett BD, Jetton TL, Ying G, Magnuson MA, Piston DW: Quantitative subcellular imaging of glucose metabolism within intact pancreatic islets. J Biol Chem 271:3647-3651, 1996
    • (1996) J Biol Chem , vol.271 , pp. 3647-3651
    • Bennett, B.D.1    Jetton, T.L.2    Ying, G.3    Magnuson, M.A.4    Piston, D.W.5
  • 27
    • 0035787576 scopus 로고    scopus 로고
    • Cell-specific roles of glucokinase in glucose homeostasis
    • Postic C, Shiota M, Magnuson MA: Cell-specific roles of glucokinase in glucose homeostasis. Recent Prog Horm Res 56:195-217, 2001
    • (2001) Recent Prog Horm Res , vol.56 , pp. 195-217
    • Postic, C.1    Shiota, M.2    Magnuson, M.A.3
  • 28
    • 0242384237 scopus 로고    scopus 로고
    • Glucokinase (GCK) mutations in hyper- and hypoglycemia: Maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy
    • Gloyn AL: Glucokinase (GCK) mutations in hyper- and hypoglycemia: maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy. Hum Mutat 22:353-362, 2003
    • (2003) Hum Mutat , vol.22 , pp. 353-362
    • Gloyn, A.L.1
  • 29
    • 0037732635 scopus 로고    scopus 로고
    • Regulation of beta cell glucokinase by S-nitrosylation and association with nitric oxide synthase
    • Rizzo MA, Piston DW: Regulation of beta cell glucokinase by S-nitrosylation and association with nitric oxide synthase. J Cell Biol 161:243-248, 2003
    • (2003) J Cell Biol , vol.161 , pp. 243-248
    • Rizzo, M.A.1    Piston, D.W.2
  • 31
    • 0033808068 scopus 로고    scopus 로고
    • The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells
    • Ort T, Maksimova E, Dirkx R, Kachinsky AM, Berghs S, Froehner SC, Solimena M: The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells. Eur J Cell Biol 79:621-630, 2000
    • (2000) Eur J Cell Biol , vol.79 , pp. 621-630
    • Ort, T.1    Maksimova, E.2    Dirkx, R.3    Kachinsky, A.M.4    Berghs, S.5    Froehner, S.C.6    Solimena, M.7
  • 32
    • 0029664605 scopus 로고    scopus 로고
    • Domains of macrophage N(O) synthase have divergent roles in forming and stabilizing the active dimeric enzyme
    • Ghosh DK, Abu-Soud HM, Stuehr DJ: Domains of macrophage N(O) synthase have divergent roles in forming and stabilizing the active dimeric enzyme. Biochemistry 35:1444-1449, 1996
    • (1996) Biochemistry , vol.35 , pp. 1444-1449
    • Ghosh, D.K.1    Abu-Soud, H.M.2    Stuehr, D.J.3
  • 33
    • 0029618106 scopus 로고
    • Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer
    • Tzeng E, Billiar TR, Robbins PD, Loftus M, Stuehr DJ: Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer. Proc Natl Acad Sci U S A 92:11771-11775, 1995
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 11771-11775
    • Tzeng, E.1    Billiar, T.R.2    Robbins, P.D.3    Loftus, M.4    Stuehr, D.J.5
  • 34
    • 0029125762 scopus 로고
    • Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer
    • Klatt P, Schmidt K, Lehner D, Glatter O, Bachinger HP, Mayer B: Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer. Embo J 14:3687-3695, 1995
    • (1995) Embo J , vol.14 , pp. 3687-3695
    • Klatt, P.1    Schmidt, K.2    Lehner, D.3    Glatter, O.4    Bachinger, H.P.5    Mayer, B.6
  • 35
  • 39
    • 0035906980 scopus 로고    scopus 로고
    • Molecular medicine: The cholesterol quartet
    • Goldstein JL, Brown MS: Molecular medicine: the cholesterol quartet. Science 292:1310-1312, 2001
    • (2001) Science , vol.292 , pp. 1310-1312
    • Goldstein, J.L.1    Brown, M.S.2
  • 40
    • 0036733578 scopus 로고    scopus 로고
    • Cholesterol, lipid rafts, and disease
    • Simons K, Ehehalt R: Cholesterol, lipid rafts, and disease. J Clin Invest 110:597-603, 2002
    • (2002) J Clin Invest , vol.110 , pp. 597-603
    • Simons, K.1    Ehehalt, R.2
  • 41
    • 15244340675 scopus 로고    scopus 로고
    • Protection by cholesterol-extracting cyclodextrins: A role for N-methyl-D-aspartate receptor redistribution
    • Abulrob A, Tauskela JS, Mealing G, Brunette E, Faid K, Stanimirovic D: Protection by cholesterol-extracting cyclodextrins: a role for N-methyl-D-aspartate receptor redistribution. J Neurochem 92:1477-1486, 2005
    • (2005) J Neurochem , vol.92 , pp. 1477-1486
    • Abulrob, A.1    Tauskela, J.S.2    Mealing, G.3    Brunette, E.4    Faid, K.5    Stanimirovic, D.6
  • 42
    • 1842639444 scopus 로고    scopus 로고
    • Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes
    • Hao M, Mukherjee S, Sun Y, Maxfield FR: Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes. J Biol Chem 279:14171-14178, 2004
    • (2004) J Biol Chem , vol.279 , pp. 14171-14178
    • Hao, M.1    Mukherjee, S.2    Sun, Y.3    Maxfield, F.R.4
  • 43
    • 0034703034 scopus 로고    scopus 로고
    • Lipid raft association of carboxypeptidase E is necessary for its function as a regulated secretory pathway sorting receptor
    • Dhanvantari S, Loh YP: Lipid raft association of carboxypeptidase E is necessary for its function as a regulated secretory pathway sorting receptor. J Biol Chem 275:29887-29893, 2000
    • (2000) J Biol Chem , vol.275 , pp. 29887-29893
    • Dhanvantari, S.1    Loh, Y.P.2
  • 44
    • 33744512465 scopus 로고    scopus 로고
    • Abnormal sterols in cholesterol-deficiency diseases cause secretory granule malformation and decreased membrane curvature
    • Gondre-Lewis MC, Petrache HI, Wassif CA, Harries D, Parsegian A, Porter FD, Loh YP: Abnormal sterols in cholesterol-deficiency diseases cause secretory granule malformation and decreased membrane curvature. J Cell Sci 119:1876-1885, 2006
    • (2006) J Cell Sci , vol.119 , pp. 1876-1885
    • Gondre-Lewis, M.C.1    Petrache, H.I.2    Wassif, C.A.3    Harries, D.4    Parsegian, A.5    Porter, F.D.6    Loh, Y.P.7
  • 48
    • 0031016436 scopus 로고    scopus 로고
    • Cholesterol absorption, synthesis, and LDL metabolism in NIDDM
    • Gylling H, Miettinen TA: Cholesterol absorption, synthesis, and LDL metabolism in NIDDM. Diabetes Care 20:90-95, 1997
    • (1997) Diabetes Care , vol.20 , pp. 90-95
    • Gylling, H.1    Miettinen, T.A.2
  • 49
    • 0029884567 scopus 로고    scopus 로고
    • Associations of fasting blood glucose with cholesterol absorption and synthesis in nondiabetic middle-aged men
    • Stranberg TE, Salomaa V, Vanhanen H, Miettinen TA: Associations of fasting blood glucose with cholesterol absorption and synthesis in nondiabetic middle-aged men. Diabetes 45:755-761, 1996
    • (1996) Diabetes , vol.45 , pp. 755-761
    • Stranberg, T.E.1    Salomaa, V.2    Vanhanen, H.3    Miettinen, T.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.