Store-operated Ca2+ entry mediated by Orai1 and TRPC1 participates to insulin secretion in rat β-cells

Journal of Biological Chemistry

Volumn 290, Issue 51, 2015, Pages 30530-30539

  Sabourin, Jessica ^a   Le Gal, Loïc ^b   Saurwein, Lisa ^b   Haefliger, Jacques Antoine ^b   Raddatz, Eric ^c   Allagnat, Florent ^b  

^a INSERM   (France)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; GLUCOSE; INSULIN; PHYSIOLOGY; RATS;

DOMINANT NEGATIVE; ENDOPLASMIC RETICULUM; EXPRESSION LEVELS; GLUCOSE CONCENTRATION; GLUCOSE-STIMULATED INSULIN SECRETIONS; INSULIN SECRETION; PANCREATIC BETA CELLS; TERNARY COMPLEX;

CALCIUM;

ACETYLCHOLINE; CALCIUM CHANNEL; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; STORE OPERATED CALCIUM CHANNEL; STROMAL INTERACTION MOLECULE 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; UNCLASSIFIED DRUG; CALCIUM; INSULIN; MEMBRANE PROTEIN; ORAI1 PROTEIN, RAT; STIM1 PROTEIN, RAT; THAPSIGARGIN; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY C, MEMBER 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL C;

ANIMAL CELL; ARTICLE; CALCIUM DEPLETION; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; EXTRACELLULAR CALCIUM; GENE OVEREXPRESSION; GLUCOSE STIMULATED INSULIN SECRETION; INSULIN RELEASE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STRUCTURE; RAT; AMINO ACID SUBSTITUTION; ANIMAL; CALCIUM SIGNALING; GENETICS; METABOLISM; MISSENSE MUTATION; PATHOLOGY; SECRETION (PROCESS); TUMOR CELL LINE;

ACETYLCHOLINE; AMINO ACID SUBSTITUTION; ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL LINE, TUMOR; INSULIN; INSULIN-SECRETING CELLS; MEMBRANE GLYCOPROTEINS; MUTATION, MISSENSE; ORAI1 PROTEIN; RATS; STROMAL INTERACTION MOLECULE 1; THAPSIGARGIN; TRPC CATION CHANNELS;

EID: 84950327120     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.682583     Document Type: Article

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