Physiological mechanisms of TRPC activation

Pflugers Archiv European Journal of Physiology

Volumn 451, Issue 1, 2005, Pages 29-34

  Putney, James W ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Calcium signaling; Diacylglycerol; Ion channels; Phospholipase C; Signal transduction; Store operated channels; TRPC channels

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; CALCIUM CHANNEL; DIACYLGLYCEROL; EPIDERMAL GROWTH FACTOR; ION CHANNEL; MESSENGER RNA; PHOSPHOLIPASE C; PROTEIN KINASE C; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL C;

CALCIUM SIGNALING; CELL MEMBRANE; DROSOPHILA; ELECTROPHYSIOLOGY; ENDOPLASMIC RETICULUM; EXPERIMENT; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; VOMERONASAL ORGAN;

ANIMALS; CALCIUM SIGNALING; DIGLYCERIDES; DROSOPHILA; MODELS, BIOLOGICAL; PHOSPHOLIPASE C; TRPC CATION CHANNELS;

EID: 26444509424     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-005-1416-4     Document Type: Review

References (84)

1. Zhu X, Chu PB, Peyton M, Birnbaumer L (1995) Molecular cloning of a widely expressed human homologue for the Drosophila trp gene. FEBS Lett 373:193-198
2. Wes PD, Chevesich J, Jeromin A, Rosenberg C, Stetten G, Montell C (1995) TRPC1, a human homolog of a Drosophila store-operated channel. Proc Natl Acad Sci USA 92:9652-9656
3. 2+ entry. Cell 85:661-671
4. 2+-permeable cation channel activated by calcium store depletion. Neuron 16:1189-1196
5. Philipp S, Cavalié A, Freichel M, Wissenbach U, Zimmer S, Trost C, Marguart A, Murakami M, Flockerzi V (1996) A mammalian capacitative calcium entry channel homologous to Drosophila TRP and TRPL. EMBO J 15:6166-6171
6. Philipp S, Hambrecht J, Braslavski L, Schroth G, Freichel M, Murakami M, Cavalié A, Flockerzi V (1998) A novel capacitative calcium entry channel expressed in excitable cells. EMBO J 17:4274-4282
7. Hofmann T, Obukhov AG, Schaefer M, Harteneck C, Gudermann T, Schultz G (1999) Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature 397:259-262
8. 2+ channel. Proc Natl Acad Sci USA 96:2060-2064
9. 2+-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor. J Biol Chem 274:27359-27370
10. Putney JW (2004) The enigmatic TRPCs: multifunctional cation channels. Trends Cell Biol 14:282-286
11. Vannier B, Zhu X, Brown D, Birnbaumer L (1998) The membrane topology of human transient receptor potential 3 as inferred from glycosylation-scanning mutagenesis and epitope immunocytochemistry. J Biol Chem 273:8675-8679
12. Hofmann T, Schaefer M, Schultz G, Gudermann T (2002) Subunit composition of mammalian transient receptor potential channels in living cells. Proc Natl Acad Sci USA 99:7461-7466
13. Strubing C, Krapivinsky G, Krapivinsky L, Clapham DE (2003) Formation of novel TRPC channels by complex subunit interactions in embryonic brain. J Biol Chem 278:39014-39019
14. Putney JW Jr (1997) Capacitative calcium entry. Landes, Austin
15. Gunthorpe MJ, Benham CD, Randall A, Davis JB (2002) The diversity in the vanilloid (TRPV) receptor family of ion channels. Trends Pharmacol Sci 23:183-191
16. Clapham DE (2003) TRP channels as cellular sensors. Nature 426:517-524
17. 2+ into mouse sperm triggered by egg ZP3. Nature Cell Biol 3:499-502
18. Liman ER, Corey DP, Dulac C (1999) TRP2: A candidate transduction channel for mammalian pheromone sensory signaling. Proc Natl Acad Sci USA 96:5791-5796
19. Stowers L, Holy TE, Meister M, Dulac C, Koentges G (2002) Loss of sex discrimination and male-male aggression in mice deficient for TRP2. Science 295:1493-1500
20. Montell C, Birnbaumer L, Flockerzi V, Bindels RJ, Bruford EA, Caterina MJ, Clapham DE, Harteneck C, Heller S, Julius D, Kojima I, Mori Y, Penner R, Prawitt D, Scharenberg AM, Schultz G, Shimizu N, Zhu MX (2002) A unified nomenclature for the superfamily of TRP cation channels. Mol Cell 9:229-231
21. 2+ mobilization. Trends Neurosci 16:371-376
22. Parekh AB, Penner R (1997) Store depletion and calcium influx. Physiol Rev 77:901-930
23. Hardie RC (2003) Regulation of trp channels via lipid second messengers. Annu Rev Physiol 65:735-759
24. 2+ influx via human Trp3 stably expressed in human embryonic kidney (HEK)293 cells. Evidence for a non-capacitative calcium entry. J Biol Chem 273:133-142
25. 3 receptors and store-operated Htrp3 channels. Nature 396:478-482
26. Trebak M, Bird GStJ, McKay RR, Birnbaumer L, Putney JW Jr (2003) Signaling mechanism for receptor-activated TRPC3 channels. J Biol Chem 278:16244-16252
27. Schaefer M, Plant TD, Obukhov AG, Hofmann T, Gudermann T, Schultz G (2000) Receptor-mediated regulation of the non-selective cation channels TRPC4 and TRPC5. J Biol Chem 275:17517-17526
28. McKay RR, Szmeczek-Seay CL, Lièvremont J-P, Bird GStJ, Zitt C, Jüngling E, Lückhoff A, Putney JW Jr (2000) Cloning and expression of the human transient receptor potential 4 (TRP4) gene: localization and functional expression of human TRP4 and TRP3. Biochem J 351:735-746
29. 2+-sensitive cation channels. J Biol Chem 275:27799-27805
30. Trebak M, Vazquez G, Bird GStJ, Putney JW Jr (2003) The TRPC3/6/7 subfamily of cation channels. Cell Calcium 33:451-461
31. Venkatachalam K, Zheng F, Gill DL (2003) Regulation of canonical transient receptor potential (TRPC) Channel function by diacylglycerol and protein kinase C. J Biol Chem 278:29031-29040
32. 2+ channel isoforms. J Biol Chem 276:13331-13339
33. Lievremont JP, Bird GS, Putney JW Jr (2004) Canonical transient receptor potential TRPC7 can function as both a receptor- and store-operated channel in HEK-293 cells. Am J Physiol 287:C1709-C1716
34. Sinkins WG, Estacion M, Schilling WP (1998) Functional expression of TrpC1: a human homologue of the Drosophila Trp channel. Biochem J 331:331-339
35. 2+ influx mechanism in salivary gland cells. J Biol Chem 275:3403-3411
36. 2+-permeable channel linked to the regulation of cell volume in liver cells obtained using small interfering RNA targeted against TRPC1. Biochem J 373:327-336
37. Strübing C, Krapivinsky G, Krapivinsky L, Clapham DE (2001) TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Neuron 29:645-655
38. Cayouette S, Lussier MP, Mathieu EL, Bousquet SM, Boulay G (2004) Exocytotic insertion of TRPC6 channel into the plasma membrane upon Gq protein-coupled receptor activation. J Biol Chem 279:7241-7246
39. 2+ influx. Mol Cell 15:635-646
40. Bezzerides VJ, Ramsey IS, Kotecha S, Greka A, Clapham DE (2004) Rapid vesicular translocation and insertion of TRP channels. Nat Cell Biol 6:709-720
41. Kanzaki M, Zhang Y-Q, Mashima H, Li L, Shibata H, Kojima I (1999) Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I. Nature Cell Biol 1:165-170
42. Vaca L, Sinkins WG, Hu Y, Kunze DL, Schilling WP (1994) Activation of recombinant trp by thapsigargin in Sf9 insect cells. Am J Physiol 267:C1501-C1505
43. Birnbaumer L, Zhu X, Jiang M, Boulay G, Peyton M, Vannier B, Brown D, Platano D, Sadeghi H, Stefani E, Birnbaumer M (1996) On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins. Proc Natl Acad Sci USA 93:15195-15202
44. 2+ through TRP-R, a rat homolog of TRP, expressed in Xenopus oocytes. Neurosci Lett 248:195-198
45. Groschner K, Hingel S, Lintschinger B, Balzer M, Romanin C, Zhu X, Schreibmayer W (1998) Trp proteins form store-operated cation channels in human vascular endothelial cells. FEBS Lett 437:101-106
46. 3 receptor gates store-operated hTrp3 channels. Mol Cell 4:423-429
47. 2+ in Xenopus oocytes expressing rat TRP4. Cell Calcium 28:151-159
48. Vazquez G, Lièvremont J-P, Bird GStJ, Putney JW Jr (2001) Trp3 forms both inositol trisphosphate receptor-dependent and independent store-operated cation channels in DT40 avian B-lymphocytes. Proc Natl Acad Sci USA 98:11777-11782
49. 2+ influx. J Biol Chem 277:12302-12309
50. Trebak M, Bird GStJ, McKay RR, Putney JW Jr (2002) Comparison of human TRPC3 channels in receptor-activated and store-operated modes. Differential sensitivity to channel blockers suggests fundamental differences in channel composition. J Biol Chem 277:21617-21623
51. Vazquez G, Wedel BJ, Trebak M, Bird GStJ, Putney JW Jr (2003) Expression level of TRPC3 channel determines its mechanism of activation. J Biol Chem 278:21649-21654
52. 2+ channels. Role of acidic amino acid residues in the S5-S6 region. J Biol Chem 278:11337-11343
53. 2+ entry pathway. FASEB J 15:1727-1738
54. Vandebrouck C, Martin D, Colson-Van Schoor M, Debaix H, Gailly P (2002) Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers. J Cell Biol 158:1089-1096
55. Baldi C, Vazquez G, Calvo JC, Boland R (2003) TRPC3-like protein is involved in the capacitative cation entry induced by 1alpha,25-dihydroxy-vitamin D3 in ROS 17/2.8 osteoblastic cells. J Cell Biochem 90:197-205
56. 2+ channels in mouse mesangial cells. Am J Physiol 287:C357-C364
57. 2+-like channels in adrenal cells. J Biol Chem 275:23965-23972
58. -/- mice. Nat Cell Biol 3:121-127
59. 2+ release from endoplasmic reticulum in B lymphocytes. J Exp Med 195:673-681
60. 2+ channel in PC12 cells (an adrenal chromaffin cell line) correlates with expression of the TRP-6 (transient receptor potential) protein. Biochem J 358:717-726
61. Jung S, Strotmann R, Schultz G, Plant TD (2002) TRPC6 is a candidate channel involved in receptor-stimulated cation currents in A7r5 smooth muscle cells. Am J Physiol 282:C347-C359
62. Levchenko A, Bruck J, Sternberg PW (2000) Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties. Proc Natl Acad Sci 97:5818-5823
63. Burack WR, Shaw AS (2000) Signal transduction: hanging on a scaffold. Curr Opin Cell Biol 12:211-216
64. Zeng F, Xu SZ, Jackson PK, McHugh D, Kumar B, Fountain SJ, Beech DJ (2004) Human TRPC5 channel activated by a multiplicity of signals in a single cell. J Physiol (Lond) 559:739-750
65. Beech DJ, Xu SZ, McHugh D, Flemming R (2003) TRPC1 store-operated cationic channel subunit. Cell Calcium 33:433-440
66. Hoth M, Penner R (1992) Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature 355:353-355
67. Hoth M, Penner R (1993) Calcium release-activated calcium current in rat mast cells. J Physiol (Lond) 465:359-386
68. Voets T, Prenen J, Fleig A, Vennekens R, Watanabe H, Hoenderop JGJ, Bindels RJM, Droogmans G, Penner R, Nilius B (2001) CaT1 and the calcium release-activated calcium channel manifest distinct pore properties. J Biol Chem 276:47767-47770
69. 2+ influx through non-specific cation channels in endothelial cells. Eur J Pharmacol 251:119-125
70. Krause E, Pfeiffer F, Schmid A, Schulz I (1996) Depletion of intracellular calcium stores activates a calcium-conducting nonselective cation current in mouse pancreatic acinar cells. J Biol Chem 271:32523-32528
71. 2+ influx in smooth muscle cells from mouse anococcygeus. Eur J Pharmacol 376:325-329
72. 2+ store depletion in vascular smooth muscle cells. J Biol Chem 276:7782-7790
73. 2+ entry in agonist-induced pulmonary vasoconstriction. Am J Physiol 280:L870-L880
74. 2+ stores in single rabbit portal vein myocytes. J Physiol (Lond) 538:717-728
75. 2+-store depletion in RBL-2H3 cells and human salivary gland cells, HSG and HSY. J Membr Biol 200:93-104
76. Philipp S, Strauss B, Hirnet D, Wissenbach U, Mery L, Flockerzi V, Hoth M (2003) TRPC3 mediates T-cell receptor-dependent calcium entry in human T-lymphocytes. J Biol Chem 278:26629-26638
77. Hassock SR, Zhu MX, Trost C, Flockerzi V, Authi KS (2002) Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel. Blood 100:2801-2811
78. 2+-permeable cation channel. Circ Res 88:325-332
79. Gamberucci A, Giurisato E, Pizzo P, Tassi M, Giunti R, McIntosh DP, Benedetti A (2002) Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products. Biochem J 364:245-254
80. Albert AP, Large WA (2003) Synergism between inositol phosphates and diacylglycerol on native TRPC6-like channels in rabbit portal vein myocytes. J Physiol (Lond) 552:789-795
81. 2+ entry mediated by TRPC3/TRPC6 proteins in rat prostate smooth muscle (PS1) cell line. J Cell Physiol 204:320-328.
82. Vazquez G, Wedel BJ, Kawasaki BT, Bird GS, Putney JW Jr (2004) Obligatory role of Src kinase in the signaling mechanism for TRPC3 cation channels. J Biol Chem 279:40521-40528
83. Trebak M, Hempel N, Wedel BJ, Smyth JT, Bird GS, Putney JW Jr (2005) Negative regulation of TRPC3 channels by protein kinase C-mediated phosphorylation of serine 712. Mol Pharmacol 67:558-563
84. 2+ entry in endothelial cells. J Biol Chem 279:20941-20949