-
1
-
-
84922380040
-
The role of P-glycoprotein in drug resistance in multiple myeloma
-
J. Abraham, N.N. Salama, and A.K. Azab The role of P-glycoprotein in drug resistance in multiple myeloma Leuk. Lymphoma 56 2015 26 33
-
(2015)
Leuk. Lymphoma
, vol.56
, pp. 26-33
-
-
Abraham, J.1
Salama, N.N.2
Azab, A.K.3
-
2
-
-
84862082975
-
Imidazoacridinone-dependent lysosomal photodestruction: A pharmacological Trojan horse approach to eradicate multidrug-resistant cancers
-
Y. Adar, M. Stark, E.E. Bram, P. Nowak-Sliwinska, H. van den Bergh, G. Szewczyk, T. Sarna, A. Skladanowski, A.W. Griffioen, and Y.G. Assaraf Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers Cell Death Dis. 3 2012 pe293
-
(2012)
Cell Death Dis.
, vol.3
, pp. pe293
-
-
Adar, Y.1
Stark, M.2
Bram, E.E.3
Nowak-Sliwinska, P.4
Van Den Bergh, H.5
Szewczyk, G.6
Sarna, T.7
Skladanowski, A.8
Griffioen, A.W.9
Assaraf, Y.G.10
-
3
-
-
84878643872
-
Lysosomal cell death at a glance
-
S. Aits, and M. Jaattela Lysosomal cell death at a glance J. Cell Sci. 126 2013 1905 1912
-
(2013)
J. Cell Sci.
, vol.126
, pp. 1905-1912
-
-
Aits, S.1
Jaattela, M.2
-
4
-
-
33846582913
-
Wilson's disease
-
A. Ala, A.P. Walker, K. Ashkan, J.S. Dooley, and M.L. Schilsky Wilson's disease Lancet 369 2007 397 408
-
(2007)
Lancet
, vol.369
, pp. 397-408
-
-
Ala, A.1
Walker, A.P.2
Ashkan, K.3
Dooley, J.S.4
Schilsky, M.L.5
-
5
-
-
0032543207
-
Defective acidification in human breast tumor cells and implications for chemotherapy
-
N. Altan, Y. Chen, M. Schindler, and S.M. Simon Defective acidification in human breast tumor cells and implications for chemotherapy J. Exp. Med. 187 1998 1583 1598
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1583-1598
-
-
Altan, N.1
Chen, Y.2
Schindler, M.3
Simon, S.M.4
-
6
-
-
0034256042
-
Regulated secretion of conventional lysosomes
-
N.W. Andrews Regulated secretion of conventional lysosomes Trends Cell Biol. 10 2000 316 321
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 316-321
-
-
Andrews, N.W.1
-
8
-
-
84921803830
-
Lysosomal storage disease: Gene therapy on both sides of the blood-brain barrier
-
E.L. Aronovich, and P.B. Hackett Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier Mol. Genet. Metab. 114 2015 83 93
-
(2015)
Mol. Genet. Metab.
, vol.114
, pp. 83-93
-
-
Aronovich, E.L.1
Hackett, P.B.2
-
9
-
-
33947375647
-
Molecular basis of antifolate resistance
-
Y.G. Assaraf Molecular basis of antifolate resistance Cancer Metastasis Rev. 26 2007 153 181
-
(2007)
Cancer Metastasis Rev.
, vol.26
, pp. 153-181
-
-
Assaraf, Y.G.1
-
10
-
-
33750975065
-
The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis
-
Y.G. Assaraf The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis Drug Resist. Updat. 9 2006 227 246
-
(2006)
Drug Resist. Updat.
, vol.9
, pp. 227-246
-
-
Assaraf, Y.G.1
-
11
-
-
38949145276
-
Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells
-
J. Bertinato, E. Swist, L.J. Plouffe, S.P. Brooks, and R.M. L'Abbe Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells Biochem. J. 409 2008 731 740
-
(2008)
Biochem. J.
, vol.409
, pp. 731-740
-
-
Bertinato, J.1
Swist, E.2
Plouffe, L.J.3
Brooks, S.P.4
L'Abbe, R.M.5
-
12
-
-
78650972288
-
Copper transporter 2 regulates endocytosis and controls tumor growth and sensitivity to cisplatin in vivo
-
B.G. Blair, C.A. Larson, P.L. Adams, P.B. Abada, C.E. Pesce, R. Safaei, and S.B. Howell Copper transporter 2 regulates endocytosis and controls tumor growth and sensitivity to cisplatin in vivo Mol. Pharmacol. 79 2011 157 166
-
(2011)
Mol. Pharmacol.
, vol.79
, pp. 157-166
-
-
Blair, B.G.1
Larson, C.A.2
Adams, P.L.3
Abada, P.B.4
Pesce, C.E.5
Safaei, R.6
Howell, S.B.7
-
13
-
-
67650359894
-
Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin
-
B.G. Blair, C.A. Larson, R. Safaei, and S.B. Howell Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin Clin. Cancer Res. 15 2009 4312 4321
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 4312-4321
-
-
Blair, B.G.1
Larson, C.A.2
Safaei, R.3
Howell, S.B.4
-
14
-
-
84896131650
-
Inhibition of the multidrug resistance P-glycoprotein: Time for a change of strategy?
-
R. Callaghan, F. Luk, and M. Bebawy Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy? Drug Metab. Dispos. 42 2014 623 631
-
(2014)
Drug Metab. Dispos.
, vol.42
, pp. 623-631
-
-
Callaghan, R.1
Luk, F.2
Bebawy, M.3
-
15
-
-
49449110827
-
Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration
-
B. Chapuy, R. Koch, U. Radunski, S. Corsham, N. Cheong, N. Inagaki, N. Ban, D. Wenzel, D. Reinhardt, A. Zapf, S. Schweyer, F. Kosari, W. Klapper, L. Truemper, and G.G. Wulf Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration Leukemia 22 2008 1576 1586
-
(2008)
Leukemia
, vol.22
, pp. 1576-1586
-
-
Chapuy, B.1
Koch, R.2
Radunski, U.3
Corsham, S.4
Cheong, N.5
Inagaki, N.6
Ban, N.7
Wenzel, D.8
Reinhardt, D.9
Zapf, A.10
Schweyer, S.11
Kosari, F.12
Klapper, W.13
Truemper, L.14
Wulf, G.G.15
-
16
-
-
70449359660
-
ABC transporter A3 facilitates lysosomal sequestration of imatinib and modulates susceptibility of chronic myeloid leukemia cell lines to this drug
-
B. Chapuy, M. Panse, U. Radunski, R. Koch, D. Wenzel, N. Inagaki, D. Haase, L. Truemper, and G.G. Wulf ABC transporter A3 facilitates lysosomal sequestration of imatinib and modulates susceptibility of chronic myeloid leukemia cell lines to this drug Haematologica 94 2009 1528 1536
-
(2009)
Haematologica
, vol.94
, pp. 1528-1536
-
-
Chapuy, B.1
Panse, M.2
Radunski, U.3
Koch, R.4
Wenzel, D.5
Inagaki, N.6
Haase, D.7
Truemper, L.8
Wulf, G.G.9
-
17
-
-
0038485704
-
Reduced endocytosis and altered lysosome function in cisplatin-resistant cell lines
-
S.S. Chauhan, X.J. Liang, A.W. Su, A. Pai-Panandiker, D.W. Shen, J.A. Hanover, and M.M. Gottesman Reduced endocytosis and altered lysosome function in cisplatin-resistant cell lines Br. J. Cancer 88 2003 1327 1334
-
(2003)
Br. J. Cancer
, vol.88
, pp. 1327-1334
-
-
Chauhan, S.S.1
Liang, X.J.2
Su, A.W.3
Pai-Panandiker, A.4
Shen, D.W.5
Hanover, J.A.6
Gottesman, M.M.7
-
18
-
-
84855418559
-
Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy
-
H.H. Chen, J.J. Yan, W.C. Chen, M.T. Kuo, Y.H. Lai, W.W. Lai, H.S. Liu, and W.C. Su Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy Lung Cancer 75 2012 228 234
-
(2012)
Lung Cancer
, vol.75
, pp. 228-234
-
-
Chen, H.H.1
Yan, J.J.2
Chen, W.C.3
Kuo, M.T.4
Lai, Y.H.5
Lai, W.W.6
Liu, H.S.7
Su, W.C.8
-
19
-
-
84906544769
-
Cisplatin in cancer therapy: Molecular mechanisms of action
-
S. Dasari, and P.B. Tchounwou Cisplatin in cancer therapy: molecular mechanisms of action Eur. J. Pharmacol. 740 2014 364 378
-
(2014)
Eur. J. Pharmacol.
, vol.740
, pp. 364-378
-
-
Dasari, S.1
Tchounwou, P.B.2
-
20
-
-
0016260069
-
Commentary. Lysosomotropic agents
-
C. de Duve, T. de Barsy, B. Poole, A. Trouet, P. Tulkens, and F. Van Hoof Commentary. Lysosomotropic agents Biochem. Pharmacol. 23 1974 2495 2531
-
(1974)
Biochem. Pharmacol.
, vol.23
, pp. 2495-2531
-
-
De Duve, C.1
De Barsy, T.2
Poole, B.3
Trouet, A.4
Tulkens, P.5
Van Hoof, F.6
-
21
-
-
28544443286
-
A chemical strategy to manipulate the intracellular localization of drugs in resistant cancer cells
-
M. Duvvuri, S. Konkar, R.S. Funk, J.M. Krise, and J.P. Krise A chemical strategy to manipulate the intracellular localization of drugs in resistant cancer cells Biochemistry 44 2005 15743 15749
-
(2005)
Biochemistry
, vol.44
, pp. 15743-15749
-
-
Duvvuri, M.1
Konkar, S.2
Funk, R.S.3
Krise, J.M.4
Krise, J.P.5
-
22
-
-
17244366637
-
Intracellular drug sequestration events associated with the emergence of multidrug resistance: A mechanistic review
-
M. Duvvuri, and J.P. Krise Intracellular drug sequestration events associated with the emergence of multidrug resistance: a mechanistic review Front. Biosci. 10 2005 1499 1509
-
(2005)
Front. Biosci.
, vol.10
, pp. 1499-1509
-
-
Duvvuri, M.1
Krise, J.P.2
-
24
-
-
0035066434
-
Intracellular P-gp contributes to functional drug efflux and resistance in acute myeloid leukaemia
-
P. Ferrao, P. Sincock, S. Cole, and L. Ashman Intracellular P-gp contributes to functional drug efflux and resistance in acute myeloid leukaemia Leuk. Res. 25 2001 395 405
-
(2001)
Leuk. Res.
, vol.25
, pp. 395-405
-
-
Ferrao, P.1
Sincock, P.2
Cole, S.3
Ashman, L.4
-
25
-
-
79953799375
-
Advances in the molecular detection of ABC transporters involved in multidrug resistance in cancer
-
J.P. Gillet, and M.M. Gottesman Advances in the molecular detection of ABC transporters involved in multidrug resistance in cancer Curr. Pharm. Biotechnol. 12 2011 686 692
-
(2011)
Curr. Pharm. Biotechnol.
, vol.12
, pp. 686-692
-
-
Gillet, J.P.1
Gottesman, M.M.2
-
26
-
-
79952996037
-
Mechanisms of amine accumulation in, and egress from, lysosomes
-
S.D. Goldman, R.S. Funk, R.A. Rajewski, and J.P. Krise Mechanisms of amine accumulation in, and egress from, lysosomes Bioanalysis 1 2009 1445 1459
-
(2009)
Bioanalysis
, vol.1
, pp. 1445-1459
-
-
Goldman, S.D.1
Funk, R.S.2
Rajewski, R.A.3
Krise, J.P.4
-
27
-
-
84865992002
-
Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance
-
N. Gonen, and Y.G. Assaraf Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance Drug Resist. Updat. 15 2012 183 210
-
(2012)
Drug Resist. Updat.
, vol.15
, pp. 183-210
-
-
Gonen, N.1
Assaraf, Y.G.2
-
28
-
-
29244474340
-
Niemann-Pick C1 protein facilitates the efflux of the anticancer drug daunorubicin from cells according to a novel vesicle-mediated pathway
-
Y. Gong, M. Duvvuri, M.B. Duncan, J. Liu, and J.P. Krise Niemann-Pick C1 protein facilitates the efflux of the anticancer drug daunorubicin from cells according to a novel vesicle-mediated pathway J. Pharmacol. Exp. Ther. 316 2006 242 247
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.316
, pp. 242-247
-
-
Gong, Y.1
Duvvuri, M.2
Duncan, M.B.3
Liu, J.4
Krise, J.P.5
-
29
-
-
0347379902
-
Separate roles for the Golgi apparatus and lysosomes in the sequestration of drugs in the multidrug-resistant human leukemic cell line HL-60
-
Y. Gong, M. Duvvuri, and J.P. Krise Separate roles for the Golgi apparatus and lysosomes in the sequestration of drugs in the multidrug-resistant human leukemic cell line HL-60 J. Biol. Chem. 278 2003 50234 50239
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50234-50239
-
-
Gong, Y.1
Duvvuri, M.2
Krise, J.P.3
-
30
-
-
82555189379
-
Lysosomal sequestration of sunitinib: A novel mechanism of drug resistance
-
K.J. Gotink, H.J. Broxterman, M. Labots, R.R. de Haas, H. Dekker, R.J. Honeywell, M.A. Rudek, L.V. Beerepoot, R.J. Musters, G. Jansen, A.W. Griffioen, Y.G. Assaraf, R. Pili, G.J. Peters, and H.M. Verheul Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance Clin. Cancer Res. 17 2011 7337 7346
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 7337-7346
-
-
Gotink, K.J.1
Broxterman, H.J.2
Labots, M.3
De Haas, R.R.4
Dekker, H.5
Honeywell, R.J.6
Rudek, M.A.7
Beerepoot, L.V.8
Musters, R.J.9
Jansen, G.10
Griffioen, A.W.11
Assaraf, Y.G.12
Pili, R.13
Peters, G.J.14
Verheul, H.M.15
-
31
-
-
82555189379
-
Lysosomal sequestration of sunitinib: A novel mechanism of drug resistance
-
K.J. Gotink, H.J. Broxterman, M. Labots, R.R. de Haas, H. Dekker, R.J. Honeywell, M.A. Rudek, L.V. Beerepoot, R.J. Musters, G. Jansen, A.W. Griffioen, Y.G. Assaraf, R. Pili, G.J. Peters, and H.M. Verheul Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance Clin. Cancer Res. 17 2012 7337 7346
-
(2012)
Clin. Cancer Res.
, vol.17
, pp. 7337-7346
-
-
Gotink, K.J.1
Broxterman, H.J.2
Labots, M.3
De Haas, R.R.4
Dekker, H.5
Honeywell, R.J.6
Rudek, M.A.7
Beerepoot, L.V.8
Musters, R.J.9
Jansen, G.10
Griffioen, A.W.11
Assaraf, Y.G.12
Pili, R.13
Peters, G.J.14
Verheul, H.M.15
-
32
-
-
84940002898
-
Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib sorafenib and pazopanib
-
K.J. Gotink, M. Rovithi, R.R. de Haas, R.J. Honeywell, H. Dekker, D. Poel, K. Azijli, G.J. Peters, H.J. Broxterman, and H.M. Verheul Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib sorafenib and pazopanib Cell. Oncol. (Dordr.) 38 2015 119 129
-
(2015)
Cell. Oncol. (Dordr.)
, vol.38
, pp. 119-129
-
-
Gotink, K.J.1
Rovithi, M.2
De Haas, R.R.3
Honeywell, R.J.4
Dekker, H.5
Poel, D.6
Azijli, K.7
Peters, G.J.8
Broxterman, H.J.9
Verheul, H.M.10
-
33
-
-
0036176510
-
Mechanisms of cancer drug resistance
-
M.M. Gottesman Mechanisms of cancer drug resistance Annu. Rev. Med. 53 2002 615 627
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 615-627
-
-
Gottesman, M.M.1
-
34
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
M.M. Gottesman, T. Fojo, and S.E. Bates Multidrug resistance in cancer: role of ATP-dependent transporters Nat. Rev. Cancer 2 2002 48 58
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
35
-
-
31844444140
-
The molecular basis of multidrug resistance in cancer: The early years of P-glycoprotein research
-
M.M. Gottesman, and V. Ling The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research FEBS Lett. 580 2006 998 1009
-
(2006)
FEBS Lett.
, vol.580
, pp. 998-1009
-
-
Gottesman, M.M.1
Ling, V.2
-
37
-
-
84876087934
-
Combating apoptosis and multidrug resistant cancers by targeting lysosomes
-
L. Groth-Pedersen, and M. Jaattela Combating apoptosis and multidrug resistant cancers by targeting lysosomes Cancer Lett. 332 2013 265 274
-
(2013)
Cancer Lett.
, vol.332
, pp. 265-274
-
-
Groth-Pedersen, L.1
Jaattela, M.2
-
38
-
-
33947235679
-
Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine
-
L. Groth-Pedersen, M.S. Ostenfeld, M. Hoyer-Hansen, J. Nylandsted, and M. Jaattela Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine Cancer Res. 67 2007 2217 2225
-
(2007)
Cancer Res.
, vol.67
, pp. 2217-2225
-
-
Groth-Pedersen, L.1
Ostenfeld, M.S.2
Hoyer-Hansen, M.3
Nylandsted, J.4
Jaattela, M.5
-
39
-
-
84899963339
-
Lysosome: The cell's 'suicidal bag' as a promising cancer target
-
M.T. Gyparaki, and A.G. Papavassiliou Lysosome: the cell's 'suicidal bag' as a promising cancer target Trends Mol. Med. 20 2014 239 241
-
(2014)
Trends Mol. Med.
, vol.20
, pp. 239-241
-
-
Gyparaki, M.T.1
Papavassiliou, A.G.2
-
40
-
-
84930622243
-
Role of transporters in the distribution of platinum-based drugs
-
S. Harrach, and G. Ciarimboli Role of transporters in the distribution of platinum-based drugs Front. Pharmacol. 6 2015 85
-
(2015)
Front. Pharmacol.
, vol.6
, pp. 85
-
-
Harrach, S.1
Ciarimboli, G.2
-
41
-
-
34250711394
-
Depletion of major vault protein increases doxorubicin sensitivity and nuclear accumulation and disrupts its sequestration in lysosomes
-
M. Herlevsen, G. Oxford, C.R. Owens, M. Conaway, and D. Theodorescu Depletion of major vault protein increases doxorubicin sensitivity and nuclear accumulation and disrupts its sequestration in lysosomes Mol. Cancer Ther. 6 2007 1804 1813
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 1804-1813
-
-
Herlevsen, M.1
Oxford, G.2
Owens, C.R.3
Conaway, M.4
Theodorescu, D.5
-
43
-
-
4844228226
-
The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells
-
A.K. Holzer, G. Samimi, K. Katano, W. Naerdemann, X. Lin, R. Safaei, and S.B. Howell The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells Mol. Pharmacol. 66 2004 817 823
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 817-823
-
-
Holzer, A.K.1
Samimi, G.2
Katano, K.3
Naerdemann, W.4
Lin, X.5
Safaei, R.6
Howell, S.B.7
-
44
-
-
84938080027
-
Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells
-
J. Hrabeta, T. Groh, M.A. Khalil, J. Poljakova, V. Adam, R. Kizek, J. Uhlik, H. Doktorova, T. Cerna, E. Frei, M. Stiborova, and T. Eckschlager Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells Int. J. Oncol. 47 2015 971 980
-
(2015)
Int. J. Oncol.
, vol.47
, pp. 971-980
-
-
Hrabeta, J.1
Groh, T.2
Khalil, M.A.3
Poljakova, J.4
Adam, V.5
Kizek, R.6
Uhlik, J.7
Doktorova, H.8
Cerna, T.9
Frei, E.10
Stiborova, M.11
Eckschlager, T.12
-
45
-
-
84896818937
-
Copper transporter 2 regulates intracellular copper and sensitivity to cisplatin
-
C.P. Huang, M. Fofana, J. Chan, C.J. Chang, and S.B. Howell Copper transporter 2 regulates intracellular copper and sensitivity to cisplatin Metallomics 6 2014 654 661
-
(2014)
Metallomics
, vol.6
, pp. 654-661
-
-
Huang, C.P.1
Fofana, M.2
Chan, J.3
Chang, C.J.4
Howell, S.B.5
-
46
-
-
0030962278
-
Vesicular anthracycline accumulation in doxorubicin-selected U-937 cells: Participation of lysosomes
-
S.J. Hurwitz, M. Terashima, N. Mizunuma, and C.A. Slapak Vesicular anthracycline accumulation in doxorubicin-selected U-937 cells: participation of lysosomes Blood 89 1997 3745 3754
-
(1997)
Blood
, vol.89
, pp. 3745-3754
-
-
Hurwitz, S.J.1
Terashima, M.2
Mizunuma, N.3
Slapak, C.A.4
-
47
-
-
0037195066
-
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals
-
S. Ishida, J. Lee, D.J. Thiele, and I. Herskowitz Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals Proc. Natl. Acad. Sci. U.S.A. 99 2002 14298 14302
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 14298-14302
-
-
Ishida, S.1
Lee, J.2
Thiele, D.J.3
Herskowitz, I.4
-
48
-
-
0032916531
-
Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: Role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration
-
G. Jansen, H. Barr, I. Kathmann, M.A. Bunni, D.G. Priest, P. Noordhuis, G.J. Peters, and Y.G. Assaraf Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration Mol. Pharmacol. 55 1999 761 769
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 761-769
-
-
Jansen, G.1
Barr, H.2
Kathmann, I.3
Bunni, M.A.4
Priest, D.G.5
Noordhuis, P.6
Peters, G.J.7
Assaraf, Y.G.8
-
49
-
-
47349131319
-
Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells
-
G.V. Kalayda, C.H. Wagner, I. Buss, J. Reedijk, and U. Jaehde Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells BMC Cancer 8 2008 p175
-
(2008)
BMC Cancer
, vol.8
, pp. p175
-
-
Kalayda, G.V.1
Wagner, C.H.2
Buss, I.3
Reedijk, J.4
Jaehde, U.5
-
50
-
-
84876664386
-
Cancer-associated lysosomal changes: Friends or foes?
-
T. Kallunki, O.D. Olsen, and M. Jaattela Cancer-associated lysosomal changes: friends or foes? Oncogene 32 2013 1995 2004
-
(2013)
Oncogene
, vol.32
, pp. 1995-2004
-
-
Kallunki, T.1
Olsen, O.D.2
Jaattela, M.3
-
51
-
-
34247490248
-
Lysosomal sequestration of amine-containing drugs: Analysis and therapeutic implications
-
A.M. Kaufmann, and J.P. Krise Lysosomal sequestration of amine-containing drugs: analysis and therapeutic implications J. Pharm. Sci. 96 2007 729 746
-
(2007)
J. Pharm. Sci.
, vol.96
, pp. 729-746
-
-
Kaufmann, A.M.1
Krise, J.P.2
-
52
-
-
84875851903
-
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells)
-
F. Kazmi, T. Hensley, C. Pope, R.S. Funk, G.J. Loewen, D.B. Buckley, and A. Parkinson Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells) Drug Metab. Dispos. 41 2013 897 905
-
(2013)
Drug Metab. Dispos.
, vol.41
, pp. 897-905
-
-
Kazmi, F.1
Hensley, T.2
Pope, C.3
Funk, R.S.4
Loewen, G.J.5
Buckley, D.B.6
Parkinson, A.7
-
53
-
-
84901624214
-
Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer
-
E.S. Kim, X. Tang, D.R. Peterson, D. Kilari, C.W. Chow, J. Fujimoto, N. Kalhor, S.G. Swisher, D.J. Stewart, I.I. Wistuba, and Z.H. Siddik Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer Lung Cancer 85 2014 88 93
-
(2014)
Lung Cancer
, vol.85
, pp. 88-93
-
-
Kim, E.S.1
Tang, X.2
Peterson, D.R.3
Kilari, D.4
Chow, C.W.5
Fujimoto, J.6
Kalhor, N.7
Swisher, S.G.8
Stewart, D.J.9
Wistuba, I.I.10
Siddik, Z.H.11
-
54
-
-
0034162887
-
Copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with cisplatin resistance
-
M. Komatsu, T. Sumizawa, M. Mutoh, Z.S. Chen, K. Terada, T. Furukawa, X.L. Yang, H. Gao, N. Miura, T. Sugiyama, and S. Akiyama Copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with cisplatin resistance Cancer Res 60 2000 1312 1316
-
(2000)
Cancer Res
, vol.60
, pp. 1312-1316
-
-
Komatsu, M.1
Sumizawa, T.2
Mutoh, M.3
Chen, Z.S.4
Terada, K.5
Furukawa, T.6
Yang, X.L.7
Gao, H.8
Miura, N.9
Sugiyama, T.10
Akiyama, S.11
-
55
-
-
84888206276
-
Multidrug resistance: Physiological principles and nanomedical solutions
-
S. Kunjachan, B. Rychlik, G. Storm, F. Kiessling, and T. Lammers Multidrug resistance: physiological principles and nanomedical solutions Adv. Drug Deliv. Rev. 65 2013 1852 1865
-
(2013)
Adv. Drug Deliv. Rev.
, vol.65
, pp. 1852-1865
-
-
Kunjachan, S.1
Rychlik, B.2
Storm, G.3
Kiessling, F.4
Lammers, T.5
-
56
-
-
0034104453
-
Resistance mechanisms associated with altered intracellular distribution of anticancer agents
-
A.K. Larsen, A.E. Escargueil, and A. Skladanowski Resistance mechanisms associated with altered intracellular distribution of anticancer agents Pharmacol. Ther. 85 2000 217 229
-
(2000)
Pharmacol. Ther.
, vol.85
, pp. 217-229
-
-
Larsen, A.K.1
Escargueil, A.E.2
Skladanowski, A.3
-
57
-
-
79960466176
-
Prognostic value of the copper transporters, CTR1 and CTR2, in patients with ovarian carcinoma receiving platinum-based chemotherapy
-
Y.Y. Lee, C.H. Choi, I.G. Do, S.Y. Song, W. Lee, H.S. Park, T.J. Song, M.K. Kim, T.J. Kim, J.W. Lee, D.S. Bae, and B.G. Kim Prognostic value of the copper transporters, CTR1 and CTR2, in patients with ovarian carcinoma receiving platinum-based chemotherapy Gynecol. Oncol. 122 2011 361 365
-
(2011)
Gynecol. Oncol.
, vol.122
, pp. 361-365
-
-
Lee, Y.Y.1
Choi, C.H.2
Do, I.G.3
Song, S.Y.4
Lee, W.5
Park, H.S.6
Song, T.J.7
Kim, M.K.8
Kim, T.J.9
Lee, J.W.10
Bae, D.S.11
Kim, B.G.12
-
58
-
-
0036840625
-
The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiae
-
X. Lin, T. Okuda, A. Holzer, and S.B. Howell The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiae Mol. Pharmacol. 62 2002 1154 1159
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 1154-1159
-
-
Lin, X.1
Okuda, T.2
Holzer, A.3
Howell, S.B.4
-
59
-
-
84863997137
-
LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis
-
B. Liu, H. Du, R. Rutkowski, A. Gartner, and X. Wang LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis Science 337 2012 351 354
-
(2012)
Science
, vol.337
, pp. 351-354
-
-
Liu, B.1
Du, H.2
Rutkowski, R.3
Gartner, A.4
Wang, X.5
-
60
-
-
84888205791
-
Rationally designed nanovehicles to overcome cancer chemoresistance
-
Y.D. Livney, and Y.G. Assaraf Rationally designed nanovehicles to overcome cancer chemoresistance Adv. Drug Deliv. Rev. 65 2013 1716 1730
-
(2013)
Adv. Drug Deliv. Rev.
, vol.65
, pp. 1716-1730
-
-
Livney, Y.D.1
Assaraf, Y.G.2
-
61
-
-
84864031724
-
Drug-drug interactions involving lysosomes: Mechanisms and potential clinical implications
-
R. Logan, R.S. Funk, E. Axcell, and J.P. Krise Drug-drug interactions involving lysosomes: mechanisms and potential clinical implications Expert Opin. Drug Metabol. Toxicol. 8 2012 943 958
-
(2012)
Expert Opin. Drug Metabol. Toxicol.
, vol.8
, pp. 943-958
-
-
Logan, R.1
Funk, R.S.2
Axcell, E.3
Krise, J.P.4
-
63
-
-
0023792145
-
The potential role of lysosomes in tissue distribution of weak bases
-
A.C. MacIntyre, and D.J. Cutler The potential role of lysosomes in tissue distribution of weak bases Biopharm. Drug Dispos. 9 1988 513 526
-
(1988)
Biopharm. Drug Dispos.
, vol.9
, pp. 513-526
-
-
MacIntyre, A.C.1
Cutler, D.J.2
-
64
-
-
84864874958
-
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
-
J.A. Martina, Y. Chen, M. Gucek, and R. Puertollano MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB Autophagy 8 2012 903 914
-
(2012)
Autophagy
, vol.8
, pp. 903-914
-
-
Martina, J.A.1
Chen, Y.2
Gucek, M.3
Puertollano, R.4
-
65
-
-
84923820926
-
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
-
D.L. Medina, S. Di Paola, I. Peluso, A. Armani, D. De Stefani, R. Venditti, S. Montefusco, A. Scotto-Rosato, C. Prezioso, A. Forrester, C. Settembre, W. Wang, Q. Gao, H. Xu, M. Sandri, R. Rizzuto, M.A. De Matteis, and A. Ballabio Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB Nat. Cell Biol. 17 2015 288 299
-
(2015)
Nat. Cell Biol.
, vol.17
, pp. 288-299
-
-
Medina, D.L.1
Di Paola, S.2
Peluso, I.3
Armani, A.4
De Stefani, D.5
Venditti, R.6
Montefusco, S.7
Scotto-Rosato, A.8
Prezioso, C.9
Forrester, A.10
Settembre, C.11
Wang, W.12
Gao, Q.13
Xu, H.14
Sandri, M.15
Rizzuto, R.16
De Matteis, M.A.17
Ballabio, A.18
-
66
-
-
80052729465
-
Transcriptional activation of lysosomal exocytosis promotes cellular clearance
-
D.L. Medina, A. Fraldi, V. Bouche, F. Annunziata, G. Mansueto, C. Spampanato, C. Puri, A. Pignata, J.A. Martina, M. Sardiello, M. Palmieri, R. Polishchuk, R. Puertollano, and A. Ballabio Transcriptional activation of lysosomal exocytosis promotes cellular clearance Dev. Cell 21 2011 421 430
-
(2011)
Dev. Cell
, vol.21
, pp. 421-430
-
-
Medina, D.L.1
Fraldi, A.2
Bouche, V.3
Annunziata, F.4
Mansueto, G.5
Spampanato, C.6
Puri, C.7
Pignata, A.8
Martina, J.A.9
Sardiello, M.10
Palmieri, M.11
Polishchuk, R.12
Puertollano, R.13
Ballabio, A.14
-
67
-
-
6444244528
-
Subcellular detection and localization of the drug transporter P-glycoprotein in cultured tumor cells
-
A. Molinari, A. Calcabrini, S. Meschini, A. Stringaro, P. Crateri, L. Toccacieli, M. Marra, M. Colone, M. Cianfriglia, and G. Arancia Subcellular detection and localization of the drug transporter P-glycoprotein in cultured tumor cells Curr. Protein Pept. Sci. 3 2002 653 670
-
(2002)
Curr. Protein Pept. Sci.
, vol.3
, pp. 653-670
-
-
Molinari, A.1
Calcabrini, A.2
Meschini, S.3
Stringaro, A.4
Crateri, P.5
Toccacieli, L.6
Marra, M.7
Colone, M.8
Cianfriglia, M.9
Arancia, G.10
-
68
-
-
84887468101
-
Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain
-
H. Ohrvik, Y. Nose, L.K. Wood, B.E. Kim, S.C. Gleber, M. Ralle, and D.J. Thiele Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain Proc. Natl. Acad. Sci. U.S.A. 110 2013 E4279 E4288
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. E4279-E4288
-
-
Ohrvik, H.1
Nose, Y.2
Wood, L.K.3
Kim, B.E.4
Gleber, S.C.5
Ralle, M.6
Thiele, D.J.7
-
69
-
-
0037442806
-
+-ATPase impair the preferential accumulation of daunomycin in lysosomes and reverse the resistance to anthracyclines in drug-resistant renal epithelial cells
-
+-ATPase impair the preferential accumulation of daunomycin in lysosomes and reverse the resistance to anthracyclines in drug-resistant renal epithelial cells Biochem. J. 370 2003 185 193
-
(2003)
Biochem. J.
, vol.370
, pp. 185-193
-
-
Ouar, Z.1
Bens, M.2
Vignes, C.3
Paulais, M.4
Pringel, C.5
Fleury, J.6
Cluzeaud, F.7
Lacave, R.8
Vandewalle, A.9
-
70
-
-
80052716148
-
Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
-
M. Palmieri, S. Impey, H. Kang, A. di Ronza, C. Pelz, M. Sardiello, and A. Ballabio Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways Hum. Mol. Genet. 20 2011 3852 3866
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 3852-3866
-
-
Palmieri, M.1
Impey, S.2
Kang, H.3
Di Ronza, A.4
Pelz, C.5
Sardiello, M.6
Ballabio, A.7
-
71
-
-
84930380295
-
Brief exposure to copper activates lysosomal exocytosis
-
K. Pena, J. Coblenz, and K. Kiselyov Brief exposure to copper activates lysosomal exocytosis Cell Calcium 57 2015 257 262
-
(2015)
Cell Calcium
, vol.57
, pp. 257-262
-
-
Pena, K.1
Coblenz, J.2
Kiselyov, K.3
-
72
-
-
84904672562
-
Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis
-
E.V. Polishchuk, M. Concilli, S. Iacobacci, G. Chesi, N. Pastore, P. Piccolo, S. Paladino, D. Baldantoni, I.S.C. van, J. Chan, C.J. Chang, A. Amoresano, F. Pane, P. Pucci, A. Tarallo, G. Parenti, N. Brunetti-Pierri, C. Settembre, A. Ballabio, and R.S. Polishchuk Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis Dev. Cell 29 2014 686 700
-
(2014)
Dev. Cell
, vol.29
, pp. 686-700
-
-
Polishchuk, E.V.1
Concilli, M.2
Iacobacci, S.3
Chesi, G.4
Pastore, N.5
Piccolo, P.6
Paladino, S.7
Baldantoni, D.8
Van, I.S.C.9
Chan, J.10
Chang, C.J.11
Amoresano, A.12
Pane, F.13
Pucci, P.14
Tarallo, A.15
Parenti, G.16
Brunetti-Pierri, N.17
Settembre, C.18
Ballabio, A.19
Polishchuk, R.S.20
more..
-
73
-
-
0041968944
-
Subcellular localization and activity of multidrug resistance proteins
-
A. Rajagopal, and S.M. Simon Subcellular localization and activity of multidrug resistance proteins Mol. Biol. Cell 14 2003 3389 3399
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 3389-3399
-
-
Rajagopal, A.1
Simon, S.M.2
-
74
-
-
84858981234
-
The CXXC motifs in the metal binding domains are required for ATP7B to mediate resistance to cisplatin
-
R. Safaei, P.L. Adams, M.H. Maktabi, R.A. Mathews, and S.B. Howell The CXXC motifs in the metal binding domains are required for ATP7B to mediate resistance to cisplatin J. Inorg. Biochem. 110 2012 8 17
-
(2012)
J. Inorg. Biochem.
, vol.110
, pp. 8-17
-
-
Safaei, R.1
Adams, P.L.2
Maktabi, M.H.3
Mathews, R.A.4
Howell, S.B.5
-
75
-
-
27644524811
-
Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells
-
R. Safaei, B.J. Larson, T.C. Cheng, M.A. Gibson, S. Otani, W. Naerdemann, and S.B. Howell Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells Mol. Cancer Ther. 4 2005 1595 1604
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 1595-1604
-
-
Safaei, R.1
Larson, B.J.2
Cheng, T.C.3
Gibson, M.A.4
Otani, S.5
Naerdemann, W.6
Howell, S.B.7
-
76
-
-
77956056644
-
-
Springer Science + Business Media Georgetown, TX; New York, NY
-
P. Saftig Lysosomes Landes Bioscience/Eurekah.com 2005 Springer Science + Business Media Georgetown, TX; New York, NY
-
(2005)
Lysosomes Landes Bioscience/Eurekah.com
-
-
Saftig, P.1
-
77
-
-
84885851739
-
Cancer: Killing from the inside
-
P. Saftig, and K. Sandhoff Cancer: killing from the inside Nature 502 2013 312 313
-
(2013)
Nature
, vol.502
, pp. 312-313
-
-
Saftig, P.1
Sandhoff, K.2
-
78
-
-
67749122634
-
A gene network regulating lysosomal biogenesis and function
-
M. Sardiello, M. Palmieri, A. di Ronza, D.L. Medina, M. Valenza, V.A. Gennarino, C. Di Malta, F. Donaudy, V. Embrione, R.S. Polishchuk, S. Banfi, G. Parenti, E. Cattaneo, and A. Ballabio A gene network regulating lysosomal biogenesis and function Science 325 2009 473 477
-
(2009)
Science
, vol.325
, pp. 473-477
-
-
Sardiello, M.1
Palmieri, M.2
Di Ronza, A.3
Medina, D.L.4
Valenza, M.5
Gennarino, V.A.6
Di Malta, C.7
Donaudy, F.8
Embrione, V.9
Polishchuk, R.S.10
Banfi, S.11
Parenti, G.12
Cattaneo, E.13
Ballabio, A.14
-
79
-
-
0029939371
-
Defective pH regulation of acidic compartments in human breast cancer cells (MCF-7) is normalized in adriamycin-resistant cells (MCF-7adr)
-
M. Schindler, S. Grabski, E. Hoff, and S.M. Simon Defective pH regulation of acidic compartments in human breast cancer cells (MCF-7) is normalized in adriamycin-resistant cells (MCF-7adr) Biochemistry 35 1996 2811 2817
-
(1996)
Biochemistry
, vol.35
, pp. 2811-2817
-
-
Schindler, M.1
Grabski, S.2
Hoff, E.3
Simon, S.M.4
-
80
-
-
84876812269
-
Signals from the lysosome: A control centre for cellular clearance and energy metabolism
-
C. Settembre, A. Fraldi, D.L. Medina, and A. Ballabio Signals from the lysosome: a control centre for cellular clearance and energy metabolism Nat. Rev. Mol. Cell Biol. 14 2013 283 296
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 283-296
-
-
Settembre, C.1
Fraldi, A.2
Medina, D.L.3
Ballabio, A.4
-
81
-
-
84857997408
-
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
-
C. Settembre, R. Zoncu, D.L. Medina, F. Vetrini, S. Erdin, S. Erdin, T. Huynh, M. Ferron, G. Karsenty, M.C. Vellard, V. Facchinetti, D.M. Sabatini, and A. Ballabio A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB EMBO J. 31 2012 1095 1108
-
(2012)
EMBO J.
, vol.31
, pp. 1095-1108
-
-
Settembre, C.1
Zoncu, R.2
Medina, D.L.3
Vetrini, F.4
Erdin, S.5
Erdin, S.6
Huynh, T.7
Ferron, M.8
Karsenty, G.9
Vellard, M.C.10
Facchinetti, V.11
Sabatini, D.M.12
Ballabio, A.13
-
82
-
-
0026777870
-
Subcellular distribution of the anticancer drug mitoxantrone in human and drug-resistant murine cells analyzed by flow cytometry and confocal microscopy and its relationship to the induction of DNA damage
-
P.J. Smith, H.R. Sykes, M.E. Fox, and I.J. Furlong Subcellular distribution of the anticancer drug mitoxantrone in human and drug-resistant murine cells analyzed by flow cytometry and confocal microscopy and its relationship to the induction of DNA damage Cancer Res. 52 1992 4000 4008
-
(1992)
Cancer Res.
, vol.52
, pp. 4000-4008
-
-
Smith, P.J.1
Sykes, H.R.2
Fox, M.E.3
Furlong, I.J.4
-
83
-
-
12344314253
-
Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells
-
I.S. Song, N. Savaraj, Z.H. Siddik, P. Liu, Y. Wei, C.J. Wu, and M.T. Kuo Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells Mol. Cancer Ther. 3 2004 1543 1549
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 1543-1549
-
-
Song, I.S.1
Savaraj, N.2
Siddik, Z.H.3
Liu, P.4
Wei, Y.5
Wu, C.J.6
Kuo, M.T.7
-
85
-
-
0030656341
-
Lysosomal and cytosolic pH as regulators of exocytosis in mouse macrophages
-
R. Sundler Lysosomal and cytosolic pH as regulators of exocytosis in mouse macrophages Acta Physiol. Scand. 161 1997 553 556
-
(1997)
Acta Physiol. Scand.
, vol.161
, pp. 553-556
-
-
Sundler, R.1
-
86
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
G. Szakacs, J.K. Paterson, J.A. Ludwig, C. Booth-Genthe, and M.M. Gottesman Targeting multidrug resistance in cancer Nat. Rev. Drug Discov. 5 2006 219 234
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
87
-
-
84893934538
-
Translocation of platinum anticancer drugs by human copper ATPases ATP7A and ATP7B
-
F. Tadini-Buoninsegni, G. Bartolommei, M.R. Moncelli, G. Inesi, A. Galliani, M. Sinisi, M. Losacco, G. Natile, and F. Arnesano Translocation of platinum anticancer drugs by human copper ATPases ATP7A and ATP7B Angew. Chem. Int. Ed. Engl. 53 2014 1297 1301
-
(2014)
Angew. Chem. Int. Ed. Engl.
, vol.53
, pp. 1297-1301
-
-
Tadini-Buoninsegni, F.1
Bartolommei, G.2
Moncelli, M.R.3
Inesi, G.4
Galliani, A.5
Sinisi, M.6
Losacco, M.7
Natile, G.8
Arnesano, F.9
-
88
-
-
35148829094
-
Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake
-
P.V. van den Berghe, D.E. Folmer, H.E. Malingre, E. van Beurden, A.E. Klomp, B. van de Sluis, M. Merkx, R. Berger, and L.W. Klomp Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake Biochem. J. 407 2007 49 59
-
(2007)
Biochem. J.
, vol.407
, pp. 49-59
-
-
Van Den Berghe, P.V.1
Folmer, D.E.2
Malingre, H.E.3
Van Beurden, E.4
Klomp, A.E.5
Van De Sluis, B.6
Merkx, M.7
Berger, R.8
Klomp, L.W.9
-
89
-
-
84865584931
-
Genetic polymorphism of copper transporter protein 1 is related to platinum resistance in Chinese non-small cell lung carcinoma patients
-
X. Xu, L. Duan, B. Zhou, R. Ma, H. Zhou, and Z. Liu Genetic polymorphism of copper transporter protein 1 is related to platinum resistance in Chinese non-small cell lung carcinoma patients Clin. Exp. Pharmacol. Physiol. 39 2012 786 792
-
(2012)
Clin. Exp. Pharmacol. Physiol.
, vol.39
, pp. 786-792
-
-
Xu, X.1
Duan, L.2
Zhou, B.3
Ma, R.4
Zhou, H.5
Liu, Z.6
-
90
-
-
84887127352
-
P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration
-
T. Yamagishi, S. Sahni, D.M. Sharp, A. Arvind, P.J. Jansson, and D.R. Richardson P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration J. Biol. Chem. 288 2013 31761 31771
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 31761-31771
-
-
Yamagishi, T.1
Sahni, S.2
Sharp, D.M.3
Arvind, A.4
Jansson, P.J.5
Richardson, D.R.6
-
91
-
-
84874728858
-
Involvement of lysosomal exocytosis in the excretion of mesoporous silica nanoparticles and enhancement of the drug delivery effect by exocytosis inhibition
-
R.E. Yanes, D. Tarn, A.A. Hwang, D.P. Ferris, S.P. Sherman, C.R. Thomas, J. Lu, A.D. Pyle, J.I. Zink, and F. Tamanoi Involvement of lysosomal exocytosis in the excretion of mesoporous silica nanoparticles and enhancement of the drug delivery effect by exocytosis inhibition Small 9 2013 697 704
-
(2013)
Small
, vol.9
, pp. 697-704
-
-
Yanes, R.E.1
Tarn, D.2
Hwang, A.A.3
Ferris, D.P.4
Sherman, S.P.5
Thomas, C.R.6
Lu, J.7
Pyle, A.D.8
Zink, J.I.9
Tamanoi, F.10
-
92
-
-
84921799144
-
Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance
-
B. Zhitomirsky, and Y.G. Assaraf Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Oncotarget 6 2015 1143 1156
-
(2015)
Oncotarget
, vol.6
, pp. 1143-1156
-
-
Zhitomirsky, B.1
Assaraf, Y.G.2
-
93
-
-
85019296770
-
The role of cytoplasmic-to-lysosomal pH gradient in hydrophobic weak base drug sequestration in lysosomes
-
B. Zhitomirsky, and Y.G. Assaraf The role of cytoplasmic-to-lysosomal pH gradient in hydrophobic weak base drug sequestration in lysosomes Cancer Cell Microenviron. 2 2015 e807
-
(2015)
Cancer Cell Microenviron.
, vol.2
, pp. e807
-
-
Zhitomirsky, B.1
Assaraf, Y.G.2
-
94
-
-
80051503951
-
Chemosensitization by phenothiazines in human lung cancer cells: Impaired resolution of gammaH2AX and increased oxidative stress elicit apoptosis associated with lysosomal expansion and intense vacuolation
-
D. Zong, P. Haag, I. Yakymovych, R. Lewensohn, and K. Viktorsson Chemosensitization by phenothiazines in human lung cancer cells: impaired resolution of gammaH2AX and increased oxidative stress elicit apoptosis associated with lysosomal expansion and intense vacuolation Cell Death Dis. 2 2011 e181
-
(2011)
Cell Death Dis.
, vol.2
, pp. e181
-
-
Zong, D.1
Haag, P.2
Yakymovych, I.3
Lewensohn, R.4
Viktorsson, K.5
-
95
-
-
84897441779
-
Harnessing the lysosome-dependent antitumor activity of phenothiazines in human small cell lung cancer
-
D. Zong, K. Zielinska-Chomej, T. Juntti, B. Mork, R. Lewensohn, P. Haag, and K. Viktorsson Harnessing the lysosome-dependent antitumor activity of phenothiazines in human small cell lung cancer Cell Death Dis. 5 2014 e1111
-
(2014)
Cell Death Dis.
, vol.5
, pp. e1111
-
-
Zong, D.1
Zielinska-Chomej, K.2
Juntti, T.3
Mork, B.4
Lewensohn, R.5
Haag, P.6
Viktorsson, K.7
|