Intracellular drug sequestration events associated with the emergence of multidrug resistance: A mechanistic review

Frontiers in Bioscience

Volumn 10, Issue 2, 2005, Pages 1499-1509

  Duvvuri, Muralikrishna ^a   Krise, Jeffrey P ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Accumulation mechanisms; Altered drug distribution; Intracellular; Intracellular drug transport; Multidrug resistance; Organelle; Review

Indexed keywords

ABC TRANSPORTER; ANTINEOPLASTIC AGENT; CELL PROTEIN; DAUNORUBICIN; DNA; DNA TOPOISOMERASE; DOXORUBICIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1;

BILAYER MEMBRANE; CANCER CELL; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CELL PH; CELLULAR DISTRIBUTION; DNA BINDING; DNA DETERMINATION; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; ELECTROCHEMISTRY; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROSCOPY; GOLGI COMPLEX; HUMAN; LIPID BILAYER; LYSOSOME MEMBRANE; MELTING POINT; MITOCHONDRIAL MEMBRANE; MULTIDRUG RESISTANCE; PH MEASUREMENT; PROTEIN FAMILY; REVIEW;

EID: 17244366637     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/1634     Document Type: Review

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