-
1
-
-
84904860154
-
Non-small-cell lung cancers: a heterogeneous set of diseases
-
Chen, Z. et al. (2014) Non-small-cell lung cancers: a heterogeneous set of diseases. Nat. Rev. Cancer, 14, 535-546.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 535-546
-
-
Chen, Z.1
-
3
-
-
58149345546
-
Co-evolution of tumor cells and their microenvironment
-
Polyak, K. et al. (2009) Co-evolution of tumor cells and their microenvironment. Trends Genet., 25, 30-38.
-
(2009)
Trends Genet
, vol.25
, pp. 30-38
-
-
Polyak, K.1
-
4
-
-
84905103883
-
Fibroblast heterogeneity in the cancer wound
-
Ohlund, D. et al. (2014) Fibroblast heterogeneity in the cancer wound. J. Exp. Med., 211, 1503-1523.
-
(2014)
J. Exp. Med
, vol.211
, pp. 1503-1523
-
-
Ohlund, D.1
-
5
-
-
79955562722
-
Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer
-
Navab, R. et al. (2011) Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer. Proc Natl Acad Sci USA, 108, 7160-7165.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 7160-7165
-
-
Navab, R.1
-
6
-
-
84921748996
-
Matrix stiffening and beta(1) integrin drive subtype-specific fibroblast accumulation in lung cancer
-
Puig, M. et al. (2015) Matrix stiffening and beta(1) integrin drive subtype-specific fibroblast accumulation in lung cancer. Mol. Cancer Res., 13, 161-173.
-
(2015)
Mol. Cancer Res
, vol.13
, pp. 161-173
-
-
Puig, M.1
-
7
-
-
70349479538
-
Highly tumorigenic lung cancer CD133(+) cells display stem-like features and are spared by cisplatin treatment
-
Bertolini, G. et al. (2009) Highly tumorigenic lung cancer CD133(+) cells display stem-like features and are spared by cisplatin treatment. Proc Natl Acad Sci USA, 106, 16281-16286.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16281-16286
-
-
Bertolini, G.1
-
8
-
-
23044499067
-
Distinct epigenetic changes in the stromal cells of breast cancers
-
Hu, M. et al. (2005) Distinct epigenetic changes in the stromal cells of breast cancers. Nat. Genetics, 37, 899-905.
-
(2005)
Nat. Genetics
, vol.37
, pp. 899-905
-
-
Hu, M.1
-
10
-
-
85027954125
-
DNA methylation profiling in the clinic: applications and challenges
-
Heyn, H. et al. (2012) DNA methylation profiling in the clinic: applications and challenges. Nat. Rev. Genetics, 13, 679-692.
-
(2012)
Nat. Rev. Genetics
, vol.13
, pp. 679-692
-
-
Heyn, H.1
-
11
-
-
67650462249
-
DNA hypomethylation in the origin and pathogenesis of human diseases
-
Pogribny, I.P. et al. (2009) DNA hypomethylation in the origin and pathogenesis of human diseases. Cell. Mol. Life Sci., 66, 2249-2261.
-
(2009)
Cell. Mol. Life Sci
, vol.66
, pp. 2249-2261
-
-
Pogribny, I.P.1
-
12
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan, D. et al. (2011) Hallmarks of cancer: the next generation. Cell, 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
-
13
-
-
84891801684
-
A prognostic DNA methylation signature for stage i non-small-cell lung cancer
-
Sandoval, J. et al. (2013) A prognostic DNA methylation signature for stage i non-small-cell lung cancer. J. Clin. Oncol., 31, 4140.
-
(2013)
J. Clin. Oncol
, vol.31
, pp. 4140
-
-
Sandoval, J.1
-
14
-
-
84924333014
-
Genes suppressed by DNA methylation in nonsmall cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition
-
Lin, S.H. et al. (2014) Genes suppressed by DNA methylation in nonsmall cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition. BMC Genomics, 15, 1079.
-
(2014)
BMC Genomics
, vol.15
, pp. 1079
-
-
Lin, S.H.1
-
15
-
-
57149111920
-
Global hypomethylation of genomic DNA in cancer-associated myofibroblasts
-
Jiang, L. et al. (2008) Global hypomethylation of genomic DNA in cancer-associated myofibroblasts. Cancer Res., 68, 9900-9908.
-
(2008)
Cancer Res
, vol.68
, pp. 9900-9908
-
-
Jiang, L.1
-
16
-
-
33744981623
-
Image processing with ImageJ
-
Abramoff, M.D. et al. (2004) Image processing with ImageJ. Biophotonics Int., 11, 36-42.
-
(2004)
Biophotonics Int
, vol.11
, pp. 36-42
-
-
Abramoff, M.D.1
-
17
-
-
79958754527
-
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
-
Sandoval, J. et al. (2011) Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics, 6, 692-702.
-
(2011)
Epigenetics
, vol.6
, pp. 692-702
-
-
Sandoval, J.1
-
18
-
-
84926507971
-
limma powers differential expression analyses for RNA-sequencing and microarray studies
-
Ritchie, M.E. et al. (2015) limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res., 43, e47.
-
(2015)
Nucleic Acids Res
, vol.43
, pp. e47
-
-
Ritchie, M.E.1
-
19
-
-
84860718683
-
clusterProfiler: an R package for comparing biological themes among gene clusters
-
Yu, G. et al. (2012) clusterProfiler: an R package for comparing biological themes among gene clusters. Omics, 16, 284-287.
-
(2012)
Omics
, vol.16
, pp. 284-287
-
-
Yu, G.1
-
20
-
-
0033982936
-
KEGG: Kyoto Encyclopedia of Genes and Genomes
-
Kanehisa, M. et al. (2000) KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res., 28, 27-30.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 27-30
-
-
Kanehisa, M.1
-
21
-
-
84891753483
-
The Reactome pathway knowledgebase
-
Croft, D. et al. (2014) The Reactome pathway knowledgebase. Nucleic Acids Res., 42, D472-D477.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D472-D477
-
-
Croft, D.1
-
22
-
-
0034069495
-
Gene ontology: tool for the unification of biology
-
Ashburner, M. et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet., 25, 25-29.
-
(2000)
The Gene Ontology Consortium. Nat. Genet
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
-
23
-
-
33745626459
-
Improved scoring of functional groups from gene expression data by decorrelating GO graph structure
-
Alexa, A. et al. (2006) Improved scoring of functional groups from gene expression data by decorrelating GO graph structure. Bioinformatics, 22, 1600-1607.
-
(2006)
Bioinformatics
, vol.22
, pp. 1600-1607
-
-
Alexa, A.1
-
24
-
-
65649116900
-
KEGGgraph: a graph approach to KEGG PATHWAY in R and bioconductor
-
Zhang, J.D. et al. (2009) KEGGgraph: a graph approach to KEGG PATHWAY in R and bioconductor. Bioinformatics, 25, 1470-1471.
-
(2009)
Bioinformatics
, vol.25
, pp. 1470-1471
-
-
Zhang, J.D.1
-
25
-
-
77349091815
-
NetPath: a public resource of curated signal transduction pathways
-
Kandasamy, K. et al. (2010) NetPath: a public resource of curated signal transduction pathways. Genome Biol., 11.
-
(2010)
Genome Biol. 11.
-
-
Kandasamy, K.1
-
26
-
-
84880063991
-
DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer
-
Javier Carmona, F. et al. (2013) DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer. Cancer Prev. Res., 6, 656-665.
-
(2013)
Cancer Prev. Res
, vol.6
, pp. 656-665
-
-
Javier Carmona, F.1
-
27
-
-
9744222878
-
Extra-dornain-a fibronectin: a new marker of fibrosis in cutaneous graft-versus-host disease
-
van der Straaten, H.M. et al. (2004) Extra-dornain-a fibronectin: a new marker of fibrosis in cutaneous graft-versus-host disease. J. Invest. Dermatol., 123, 1057-1062.
-
(2004)
J. Invest. Dermatol
, vol.123
, pp. 1057-1062
-
-
van der Straaten, H.M.1
-
28
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak, K.J. et al. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods, 25, 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
-
29
-
-
84864966601
-
Mechanical waves during tissue expansion
-
Serra-Picamal, X. et al. (2012) Mechanical waves during tissue expansion. Nat. Phys., 8, 628-666.
-
(2012)
Nat. Phys
, vol.8
, pp. 628-666
-
-
Serra-Picamal, X.1
-
30
-
-
45849111041
-
Micropatterning of single endothelial cell shape reveals a tight coupling between nuclear volume in G1 and proliferation
-
Roca-Cusachs, P. et al. (2008) Micropatterning of single endothelial cell shape reveals a tight coupling between nuclear volume in G1 and proliferation. Biophys. J., 94, 4984-4995.
-
(2008)
Biophys. J
, vol.94
, pp. 4984-4995
-
-
Roca-Cusachs, P.1
-
31
-
-
84855369366
-
Identification of genes upregulated in ALKpositive and EGFR/KRAS/ALK-negative lung adenocarcinomas
-
Okayama, H. et al. (2012) Identification of genes upregulated in ALKpositive and EGFR/KRAS/ALK-negative lung adenocarcinomas. Cancer Res., 72, 100-111.
-
(2012)
Cancer Res
, vol.72
, pp. 100-111
-
-
Okayama, H.1
-
32
-
-
33646384428
-
Fibroblasts in cancer
-
Kalluri, R. et al. (2006) Fibroblasts in cancer. Nat. Rev. Cancer, 6, 392-401.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 392-401
-
-
Kalluri, R.1
-
33
-
-
73449133450
-
The role of circulating mesenchymal progenitor cells, fibrocytes, in promoting pulmonary fibrosis
-
Strieter, R.M. et al. (2009) The role of circulating mesenchymal progenitor cells, fibrocytes, in promoting pulmonary fibrosis. Trans. Am. Clin. Climatol. Assoc., 120, 49-59.
-
(2009)
Trans. Am. Clin. Climatol. Assoc
, vol.120
, pp. 49-59
-
-
Strieter, R.M.1
-
34
-
-
34547960749
-
The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses
-
Bellini, A. et al. (2007) The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses. Lab. Invest., 87, 858-870.
-
(2007)
Lab. Invest
, vol.87
, pp. 858-870
-
-
Bellini, A.1
-
35
-
-
84879251931
-
The epigenetic feedback loop between DNA methylation and microRNAs in fibrotic disease with an emphasis on DNA methyltransferases
-
Sun, X. et al. (2013) The epigenetic feedback loop between DNA methylation and microRNAs in fibrotic disease with an emphasis on DNA methyltransferases. Cell. Signal., 25, 1870-1876.
-
(2013)
Cell. Signal
, vol.25
, pp. 1870-1876
-
-
Sun, X.1
-
36
-
-
0033195998
-
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response
-
Ashcroft, G.S. et al. (1999) Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response. Nat. Cell Biol., 1, 260-266.
-
(1999)
Nat. Cell Biol
, vol.1
, pp. 260-266
-
-
Ashcroft, G.S.1
-
37
-
-
84872512565
-
Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma
-
Shakya, R. et al. (2013) Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma. Cancer Res., 73, 885-896.
-
(2013)
Cancer Res
, vol.73
, pp. 885-896
-
-
Shakya, R.1
-
38
-
-
73249146755
-
DNA hypomethylation in rheumatoid arthritis synovial fibroblasts
-
Karouzakis, E. et al. (2009) DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. Arthritis Rheumat., 60, 3613-3622.
-
(2009)
Arthritis Rheumat
, vol.60
, pp. 3613-3622
-
-
Karouzakis, E.1
-
39
-
-
77954614145
-
Epigenetic regulation of myofibroblast differentiation by DNA methylation
-
Hu, B. et al. (2010) Epigenetic regulation of myofibroblast differentiation by DNA methylation. Am. J. Pathol., 177, 21-28.
-
(2010)
Am. J. Pathol
, vol.177
, pp. 21-28
-
-
Hu, B.1
-
40
-
-
84865793866
-
Prostaglandin E2 increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression
-
Huang, S.K. et al. (2012) Prostaglandin E2 increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression. FASEB J., 26, 3703-3714.
-
(2012)
FASEB J
, vol.26
, pp. 3703-3714
-
-
Huang, S.K.1
-
41
-
-
0035689762
-
Malignant cells, directors of the malignant process: role of transforming growth factor-beta
-
Teicher, B.A. (2001) Malignant cells, directors of the malignant process: role of transforming growth factor-beta. Cancer Metast. Rev., 20, 133-143.
-
(2001)
Cancer Metast. Rev
, vol.20
, pp. 133-143
-
-
Teicher, B.A.1
-
42
-
-
79751501829
-
Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth
-
Quante, M. et al. (2011) Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer Cell, 19, 257-272.
-
(2011)
Cancer Cell
, vol.19
, pp. 257-272
-
-
Quante, M.1
-
43
-
-
78149478781
-
Aberrant epigenetic landscape in cancer: how cellular identity goes awry
-
Berdasco, M. et al. (2010) Aberrant epigenetic landscape in cancer: how cellular identity goes awry. Dev. Cell, 19, 698-711.
-
(2010)
Dev. Cell
, vol.19
, pp. 698-711
-
-
Berdasco, M.1
-
45
-
-
84923118816
-
The RUNX family: developmental regulators in cancer
-
Ito, Y. et al. (2015) The RUNX family: developmental regulators in cancer. Nat. Rev. Cancer, 15, 81-95.
-
(2015)
Nat. Rev. Cancer
, vol.15
, pp. 81-95
-
-
Ito, Y.1
-
46
-
-
84859456946
-
Smoking attenuates transforming growth factor-beta-mediated tumor suppression function through downregulation of Smad3 in lung cancer
-
Samanta, D. et al. (2012) Smoking attenuates transforming growth factor-beta-mediated tumor suppression function through downregulation of Smad3 in lung cancer. Cancer Prev. Res., 5, 453-463.
-
(2012)
Cancer Prev. Res
, vol.5
, pp. 453-463
-
-
Samanta, D.1
-
47
-
-
33847084614
-
Formation and function of the myofibroblast during tissue repair
-
Hinz, B. (2007) Formation and function of the myofibroblast during tissue repair. J. Invest. Dermatol., 127, 526-537.
-
(2007)
J. Invest. Dermatol
, vol.127
, pp. 526-537
-
-
Hinz, B.1
-
48
-
-
0042831330
-
Smad3 mediates transforming growth factor-betainduced alpha-smooth muscle actin expression
-
Hu, B. et al. (2003) Smad3 mediates transforming growth factor-betainduced alpha-smooth muscle actin expression. Am. J. Respir. Cell Mol. Biol., 29, 397-404.
-
(2003)
Am. J. Respir. Cell Mol. Biol
, vol.29
, pp. 397-404
-
-
Hu, B.1
-
49
-
-
84865036458
-
Fibrocytes: emerging effector cells in chronic inflammation
-
Peng, H. et al. (2012) Fibrocytes: emerging effector cells in chronic inflammation. Curr. Opin. Pharmacol., 12, 491-496.
-
(2012)
Curr. Opin. Pharmacol
, vol.12
, pp. 491-496
-
-
Peng, H.1
-
50
-
-
0035924366
-
Gene defect in ectodermal dysplasia implicates a death domain adapter in development
-
Headon, D.J. et al. (2001) Gene defect in ectodermal dysplasia implicates a death domain adapter in development. Nature, 414, 913-916.
-
(2001)
Nature
, vol.414
, pp. 913-916
-
-
Headon, D.J.1
|