Smoking attenuates transforming growth factor-β-mediated tumor suppression function through downregulation of Smad3 in lung cancer

Cancer Prevention Research

Volumn 5, Issue 3, 2012, Pages 453-463

  Samanta, Debangshu ^a   Gonzalez, Adriana L ^a,b   Nagathihalli, Nagaraj ^a   Ye, Fei ^a   Carbone, David P ^a,b   Datta, Pran K ^a,b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT INGRAM CANCER CENTER   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE CONDENSATE; DIMETHYL SULFOXIDE; PROTEIN BCL 2; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CANCER CELL; CANCER INHIBITION; CARCINOGENICITY; CELL IMMORTALIZATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SMOKING; UPREGULATION;

ACETYLATION; ADENOCARCINOMA; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRONCHI; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; CELLS, CULTURED; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; HISTONES; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; LUNG NEOPLASMS; MICE; MICE, NUDE; PHOSPHORYLATION; PROTEIN BINDING; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; SMALL CELL LUNG CARCINOMA; SMOKING; SURVIVAL RATE; TISSUE ARRAY ANALYSIS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 84859456946     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-11-0313     Document Type: Article

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