Fibrocytes: Emerging effector cells in chronic inflammation

Current Opinion in Pharmacology

Volumn 12, Issue 4, 2012, Pages 491-496

  Peng, Hong ^a,b   Herzog, Erica L ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CAVEOLIN; CD11 ANTIGEN; CD11B ANTIGEN; CD11D ANTIGEN; CD32 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; CD64 ANTIGEN; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR4; COLLAGEN TYPE 1; COLLAGEN TYPE 4; COLLAGEN TYPE 5; GAMMA INTERFERON; GLYCOPROTEIN P 15095; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; SEMAPHORIN; SEMAPHORIN 7A; TOLL LIKE RECEPTOR AGONIST; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

AGING; AUTOIMMUNITY; CELL DIFFERENTIATION; CELL FUNCTION; CELL HOMING; CELL MIGRATION; CELL STRUCTURE; CELL SURFACE; CHRONIC INFLAMMATION; CYTOKINE RELEASE; DISEASE ASSOCIATION; EFFECTOR CELL; FIBROCYTE; HUMAN; LIVER DISEASE; LUNG DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW;

AGING; ANIMALS; BONE MARROW CELLS; HUMANS; INFLAMMATION;

EID: 84865036458     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2012.03.002     Document Type: Review

References (46)

1. Y. Liu Renal fibrosis: new insights into the pathogenesis and therapeutics Kidney Int 69 2006 213 217
2. A. Moeller, S.E. Gilpin, K. Ask, G. Cox, D. Cook, J. Gauldie, P.J. Margetts, L. Farkas, J. Dobranowski, and C. Boylan Circulating fibrocytes are an indicator for poor prognosis in idiopathic pulmonary fibrosis Am J Respir Crit Care Med 179 2009 588 594
3. Y. Gan, R.A. Reilkoff, X. Peng, T.R. Russell, Q.C. Chen, S.K. Mathai, M. Gulati, R.J. Homer, J.A. Elias, R.J. Bucala, and E.L. Herzog Role of Semaphorin 7a in TGF b1 induced lung fibrosis, and scleroderma-related interstitial lung disease Arth Rheum 63 2011 2484 2494
4. X. Peng, S.K. Mathai, L.A. Murray, T. Russell, R. Reilkoff, Q. Chen, M. Gulati, J.A. Elias, R. Bucala, Y. Gan, and E.L. Herzog Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor beta1-induced lung fibrosis Fibrogenesis Tissue Repair 4 2011 12
5. S.K. Mathai, M. Gulati, X. Peng, T.R. Russell, A.C. Shaw, A.N. Rubinowitz, L.A. Murray, J.M. Siner, D.E. Antin-Ozerkis, and R.R. Montgomery Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype Lab Invest 90 2010 812 823
6. C.L. Galligan, K.A. Siminovitch, E.C. Keystone, V. Bykerk, O.D. Perez, and E.N. Fish Fibrocyte activation in rheumatoid arthritis Rheumatology (Oxford) 49 2010 640 651
7. D. Scholten, D. Reichart, Y.H. Paik, J. Lindert, J. Bhattacharya, C.K. Glass, D.A. Brenner, and T. Kisseleva Migration of fibrocytes in fibrogenic liver injury Am J Pathol 179 2011 189 198
8. A. Medina, and A. Ghahary Reprogrammed fibrocytes induce a mixed Th1/Th2 cytokine response of naive CD4(+) T cells Mol Cell Biochem 346 2011 89 94
9. R.A. Reilkoff, R. Bucala, and E.L. Herzog Fibrocytes: emerging effector cells in chronic inflammation Nat Rev Immunol 11 2011 427 435
10. D. Pilling, T. Fan, D. Huang, B. Kaul, and R.H. Gomer Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts PLoS ONE 4 2009 e7475
11. J.E. Ekert, L.A. Murray, A.M. Das, H. Sheng, J. Giles-Komar, and M.A. Rycyzyn Chemokine (C-C motif) ligand 2 mediates direct and indirect fibrotic responses in human and murine cultured fibrocytes Fibrogenesis Tissue Repair 4 2012 23
12. B. Mehrad, M.D. Burdick, and R.M. Strieter Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis Int J Biochem Cell Biol 41 2009 1708 1718
13. T. Kisseleva, M. von Kockritz-Blickwede, D. Reichart, S.M. McGillvray, G. Wingender, M. Kronenberg, C.K. Glass, V. Nizet, and D.A. Brenner Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection J Mol Med (Berl) 89 2012 997 1013
14. M. Schmidt, G. Sun, M.A. Stacey, L. Mori, and S. Mattoli Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma J Immunol 171 2003 380 389
15. L. Bianchetti, M. Barczyk, J. Cardoso, M. Schmidt, A. Bellini, and S. Mattoli Extracellular matrix remodelling properties of human fibrocytes J Cell Mol Med 16 2012 483 495
16. S.J. Curnow, M. Fairclough, C. Schmutz, S. Kissane, A.K. Denniston, K. Nash, C.D. Buckley, J.M. Lord, and M. Salmon Distinct types of fibrocyte can differentiate from mononuclear cells in the presence and absence of serum PLoS ONE 5 2010 e9730
17. M. Niedermeier, B. Reich, M.R. Gomez, A. Denzel, K. Schmidbauer, N. Gobel, Y. Talke, F. Schweda, and M. Mack CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes Proc Natl Acad Sci USA 106 2009 17892 17897
18. D. Pilling, N.M. Tucker, and R.H. Gomer Aggregated IgG inhibits the differentiation of human fibrocytes J Leukoc Biol 79 2006 1242 1251
19. D. Pilling, C.D. Buckley, M. Salmon, and R.H. Gomer Inhibition of fibrocyte differentiation by serum amyloid P J Immunol 171 2003 5537 5546
20. D. Pilling, D. Roife, M. Wang, S.D. Ronkainen, J.R. Crawford, E.L. Travis, and R.H. Gomer Reduction of bleomycin-induced pulmonary fibrosis by serum amyloid P J Immunol 179 2007 4035 4044
21. L.A. Murray, Q. Chen, M.S. Kramer, D.P. Hesson, R.L. Argentieri, X. Peng, M. Gulati, R.J. Homer, T. Russell, and N. van Rooijen TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum Amyloid P Int J Biochem Cell Biol 43 2011 154 162
22. A.P. Castano, S.L. Lin, T. Surowy, B.T. Nowlin, S.A. Turlapati, T. Patel, A. Singh, S. Li, M.L. Lupher Jr., and J.S. Duffield Serum amyloid P inhibits fibrosis through Fc gamma R-dependent monocyte-macrophage regulation in vivo Sci Transl Med 1 2009 ra13
23. A.S. Maharjan, D. Pilling, and R.H. Gomer High and low molecular weight hyaluronic acid differentially regulate human fibrocyte differentiation PLoS ONE 6 2011 e26078
24. D.D. Shao, R. Suresh, V. Vakil, R.H. Gomer, and D. Pilling Pivotal advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation J Leukoc Biol 83 2008 1323 1333
25. y. Gan, R.A. Reilkoff, x. Peng, T.R. Russell, Q.C. Chen, S.K. Mathai, M. Gulati, R.J. Homer, J.A. Elias, R.J. Bucala, and E.L. Herzog Role of Semaphorin 7a in TGF b1 induced lung fibrosis, and scleroderma-related interstitial lung disease Arth Rheum 63 2011 2484 2494
26. V.S. Nikam, G. Wecker, R. Schermuly, U. Rapp, K. Szelepusa, W. Seeger, and R. Voswinckel Treprostinil inhibits adhesion and differentiation of fibrocytes via cAMP and Rap dependent ERK inactivation Am J Respir Cell Mol Biol 45 2011 692 703
27. A.S. Maharjan, D. Pilling, and R.H. Gomer Toll-like receptor 2 agonists inhibit human fibrocyte differentiation Fibrogenesis Tissue Repair 3 2011 23
28. E. Tourkina, M. Bonner, J. Oates, A. Hofbauer, M. Richard, S. Znoyko, R.P. Visconti, J. Zhang, C.M. Hatfield, R.M. Silver, and S. Hoffman Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: reversal by caveolin-1 scaffolding domain peptide Fibrogenesis Tissue Repair 4 2011 15
29. N. Sakai, T. Wada, H. Yokoyama, M. Lipp, S. Ueha, K. Matsushima, and S. Kaneko Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis Proc Natl Acad Sci USA 103 2006 14098 14103
30. R. Abe, S.C. Donnelly, T. Peng, R. Bucala, and C.N. Metz Peripheral blood fibrocytes: differentiation pathway and migration to wound sites J Immunol 166 2001 7556 7562
31. B. Mehrad, M.D. Burdick, D.A. Zisman, M.P. Keane, J.A. Belperio, and R.M. Strieter Circulating peripheral blood fibrocytes in human fibrotic interstitial lung disease Biochem Biophys Res Commun 353 2007 104 108
32. T. Kisseleva, H. Uchinami, N. Feirt, O. Quintana-Bustamante, J.C. Segovia, R.F. Schwabe, and D.A. Brenner Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis J Hepatol 45 2006 429 438
33. R.J. Phillips, M.D. Burdick, K. Hong, M.A. Lutz, L.A. Murray, Y.Y. Xue, J.A. Belperio, M.P. Keane, and R.M. Strieter Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis J Clin Invest 114 2004 438 446
34. J. Chesney, C. Metz, A.B. Stavitsky, M. Bacher, and R. Bucala Regulated production of type I collagen and inflammatory cytokines by peripheral blood fibrocytes J Immunol 160 1998 419 425
35. A. Bellini, M.A. Marini, L. Bianchetti, M. Barczyk, M. Schmidt, and S. Mattoli Interleukin (IL)-4 IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients Mucosal Immunol 5 2012 140 149
36. J. Chesney, M. Bacher, A. Bender, and R. Bucala The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ Proc Natl Acad Sci USA 94 1997 6307 6312
37. I. Hartlapp, R. Abe, R.W. Saeed, T. Peng, W. Voelter, R. Bucala, and C.N. Metz Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo FASEB J 15 2001 2215 2224
38. M. Kraman, P.J. Bambrough, J.N. Arnold, E.W. Roberts, L. Magiera, J.O. Jones, A. Gopinathan, D.A. Tuveson, and D.T. Fearon Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha Science 330 2010 827 830
39. H.W. van Deventer, Q.P. Wu, D.T. Bergstralh, B.K. Davis, B.P. O'Connor, J.P. Ting, and J.S. Serody C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9 Am J Pathol 173 2008 253 264
40. C. Quesnel, P. Piednoir, J. Gelly, L. Nardelli, M. Garnier, V. Lecon, S. Lasocki, L. Bouadma, I. Philip, and C. Elbim Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury Crit Care Med 40 2012 21 28
41. C. Garcia-de-Alba, C. Becerril, V. Ruiz, Y. Gonzalez, S. Reyes, J. Garcia-Alvarez, M. Selman, and A. Pardo Expression of matrix metalloproteases by fibrocytes: possible role in migration and homing Am J Respir Crit Care Med 182 2010 1144 1152
42. K. Nihlberg, K. Larsen, A. Hultgardh-Nilsson, A. Malmstrom, L. Bjermer, and G. Westergren-Thorsson Tissue fibrocytes in patients with mild asthma: a possible link to thickness of reticular basement membrane? Respir Res 7 2006 50
43. D.J. LaPar, M.D. Burdick, A. Emaminia, D.A. Harris, B.A. Strieter, L. Liu, M. Robbins, I.L. Kron, R.M. Strieter, and C.L. Lau Circulating fibrocytes correlate with bronchiolitis obliterans syndrome development after lung transplantation: a novel clinical biomarker Ann Thorac Surg 92 2011 470 477
44. A. Andersson-Sjoland, J.S. Erjefalt, L. Bjermer, L. Eriksson, and G. Westergren-Thorsson Fibrocytes are associated with vascular and parenchymal remodelling in patients with obliterative bronchiolitis Respir Res 10 2009 103
45. R.S. Douglas, N.F. Afifiyan, C.J. Hwang, K. Chong, U. Haider, P. Richards, A.G. Gianoukakis, and T.J. Smith Increased generation of fibrocytes in thyroid-associated ophthalmopathy J Clin Endocrinol Metab 95 2011 430 438
46. J. Xu, E.T. Gonzalez, S.S. Iyer, V. Mac, A.L. Mora, R.L. Sutliff, A. Reed, K.L. Brigham, P. Kelly, and M. Rojas Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice J Gerontol A Biol Sci Med Sci 64 2009 731 739