Melatonin induces cell apoptosis in AGS cells through the activation of JNK and P38 MAPK and the suppression of nuclear Factor-Kappa B: A novel therapeutic implication for gastric cancer

Cellular Physiology and Biochemistry

Volumn 37, Issue 6, 2015, Pages 2323-2338

  Li, Weimin ^a   Fan, Mengdi ^a   Chen, Yina ^a   Zhao, Qian ^a   Song, Caiyun ^a   Yan, Ye ^a   Jin, Yin ^a   Huang, Zhiming ^a   Lin, Chunjing ^a   Wu, Jiansheng ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Melatonin; Mitogen activated protein kinases; Nuclear factor kappa B

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CISPLATIN; CYTOMEGALOVIRUS ANTIGEN PP65; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MELATONIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL VIABILITY; CLONOGENESIS; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; ENZYME ACTIVATION; GASTRIC CANCER CELL LINE; GENE TRANSLOCATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; STOMACH CANCER; UPREGULATION; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYMOLOGY; HUMAN; METABOLISM; PATHOLOGY; STOMACH NEOPLASMS; TUMOR CELL LINE; TUMOR INVASION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CISPLATIN; DRUG SYNERGISM; ENZYME ACTIVATION; HUMANS; MAP KINASE KINASE 4; MELATONIN; NEOPLASM INVASIVENESS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; STOMACH NEOPLASMS;

EID: 84949561968     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000438587     Document Type: Article

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