-
1
-
-
8144230178
-
Suz12 is essential for mouse development and for ezh2 histone methyltransferase activity
-
Pasini D, Bracken AP, Jensen MR, Lazzerini Denchi E, Helin K: Suz12 is essential for mouse development and for ezh2 histone methyltransferase activity. EMBO J 2004;23:4061-4071.
-
(2004)
EMBO J
, vol.23
, pp. 4061-4071
-
-
Pasini, D.1
Bracken, A.P.2
Jensen, M.R.3
Lazzerini Denchi, E.4
Helin, K.5
-
2
-
-
3042801308
-
Suz12 is required for both the histone methyltransferase activity and the silencing function of the eed-ezh2 complex
-
Cao R, Zhang Y: Suz12 is required for both the histone methyltransferase activity and the silencing function of the eed-ezh2 complex. Mol Cell 2004;15:57-67.
-
(2004)
Mol Cell
, vol.15
, pp. 57-67
-
-
Cao, R.1
Zhang, Y.2
-
3
-
-
84869225502
-
Suz12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing hrk
-
Li H, Cai Q, Wu H, Vathipadiekal V, Dobbin ZC, Li T, Hua X, Landen CN, Birrer MJ, Sanchez-Beato M, Zhang R: Suz12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing hrk. Mol Cancer Res 2012;10:1462-1472.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 1462-1472
-
-
Li, H.1
Cai, Q.2
Wu, H.3
Vathipadiekal, V.4
Dobbin, Z.C.5
Li, T.6
Hua, X.7
Landen, C.N.8
Birrer, M.J.9
Sanchez-Beato, M.10
Zhang, R.11
-
4
-
-
77956547097
-
Loss of mir-200 inhibition of suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells
-
Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K: Loss of mir-200 inhibition of suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol Cell 2010;39:761-772.
-
(2010)
Mol Cell
, vol.39
, pp. 761-772
-
-
Iliopoulos, D.1
Lindahl-Allen, M.2
Polytarchou, C.3
Hirsch, H.A.4
Tsichlis, P.N.5
Struhl, K.6
-
5
-
-
77957256995
-
Deregulated expression of the polycomb-group protein suz12 target genes characterizes mantle cell lymphoma
-
Martin-Perez D, Sanchez E, Maestre L, Suela J, Vargiu P, Di Lisio L, Martinez N, Alves J, Piris MA, Sanchez-Beato M: Deregulated expression of the polycomb-group protein suz12 target genes characterizes mantle cell lymphoma. Am J Pathol 2010;177:930-942.
-
(2010)
Am J Pathol
, vol.177
, pp. 930-942
-
-
Martin-Perez, D.1
Sanchez, E.2
Maestre, L.3
Suela, J.4
Vargiu, P.5
Di Lisio, L.6
Martinez, N.7
Alves, J.8
Piris, M.A.9
Sanchez-Beato, M.10
-
6
-
-
38049134281
-
Effects of rearrangement and allelic exclusion of jjaz1/suz12 on cell proliferation and survival
-
Li H, Ma X, Wang J, Koontz J, Nucci M, Sklar J: Effects of rearrangement and allelic exclusion of jjaz1/suz12 on cell proliferation and survival. Proc Natl Acad Sci U S A 2007;104:20001-20006.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20001-20006
-
-
Li, H.1
Ma, X.2
Wang, J.3
Koontz, J.4
Nucci, M.5
Sklar, J.6
-
7
-
-
55149119362
-
Expression parameters of the polycomb group proteins bmi1, suz12, ring1 and cbx7 in urothelial carcinoma of the bladder and their prognostic relevance
-
Hinz S, Kempkensteffen C, Christoph F, Krause H, Schrader M, Schostak M, Miller K, Weikert S: Expression parameters of the polycomb group proteins bmi1, suz12, ring1 and cbx7 in urothelial carcinoma of the bladder and their prognostic relevance. Tumour Biol 2008;29:323-329.
-
(2008)
Tumour Biol
, vol.29
, pp. 323-329
-
-
Hinz, S.1
Kempkensteffen, C.2
Christoph, F.3
Krause, H.4
Schrader, M.5
Schostak, M.6
Miller, K.7
Weikert, S.8
-
8
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D: Global cancer statistics. CA Cancer J Clin 2011;61:69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
9
-
-
0032437406
-
Epidemiology of cancer: Global patterns and trends
-
Parkin DM: Epidemiology of cancer: Global patterns and trends. Toxicol Lett1998;102-103:227-234.
-
(1998)
Toxicol Lett
, vol.102-103
, pp. 227-234
-
-
Parkin, D.M.1
-
10
-
-
84873587945
-
Prognostic significance of overexpression of ezh2 and h3k27me3 proteins in gastric cancer
-
He LJ, Cai MY, Xu GL, Li JJ, Weng ZJ, Xu DZ, Luo GY, Zhu SL, Xie D: Prognostic significance of overexpression of ezh2 and h3k27me3 proteins in gastric cancer. Asian Pac J Cancer Prev 2012;13:3173-3178.
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 3173-3178
-
-
He, L.J.1
Cai, M.Y.2
Xu, G.L.3
Li, J.J.4
Weng, Z.J.5
Xu, D.Z.6
Luo, G.Y.7
Zhu, S.L.8
Xie, D.9
-
11
-
-
84864749110
-
Lack of microrna-101 causes e-cadherin functional deregulation through ezh2 up-regulation in intestinal gastric cancer
-
Carvalho J, van Grieken NC, Pereira PM, Sousa S, Tijssen M, Buffart TE, Diosdado B, Grabsch H, Santos MA, Meijer G, Seruca R, Carvalho B, Oliveira C: Lack of microrna-101 causes e-cadherin functional deregulation through ezh2 up-regulation in intestinal gastric cancer. J Pathol 2012;228:31-44.
-
(2012)
J Pathol
, vol.228
, pp. 31-44
-
-
Carvalho, J.1
Van Grieken, N.C.2
Pereira, P.M.3
Sousa, S.4
Tijssen, M.5
Buffart, T.E.6
Diosdado, B.7
Grabsch, H.8
Santos, M.A.9
Meijer, G.10
Seruca, R.11
Carvalho, B.12
Oliveira, C.13
-
12
-
-
33845437420
-
Immunohistochemical analysis of prb2/p130, vegf, ezh2, p53, p16(ink4a), p27(kip1), p21(waf1), ki-67 expression patterns in gastric cancer
-
Mattioli E, Vogiatzi P, Sun A, Abbadessa G, Angeloni G, D'Ugo D, Trani D, Gaughan JP, Vecchio FM, Cevenini G, Persiani R, Giordano A, Claudio PP: Immunohistochemical analysis of prb2/p130, vegf, ezh2, p53, p16(ink4a), p27(kip1), p21(waf1), ki-67 expression patterns in gastric cancer. J Cell Physiol 2007;210:183-191.
-
(2007)
J Cell Physiol
, vol.210
, pp. 183-191
-
-
Mattioli, E.1
Vogiatzi, P.2
Sun, A.3
Abbadessa, G.4
Angeloni, G.5
D'Ugo, D.6
Trani, D.7
Gaughan, J.P.8
Vecchio, F.M.9
Cevenini, G.10
Persiani, R.11
Giordano, A.12
Claudio, P.P.13
-
13
-
-
77953148103
-
Downregulation of microrna-200 in ebv-associated gastric carcinoma
-
Shinozaki A, Sakatani T, Ushiku T, Hino R, Isogai M, Ishikawa S, Uozaki H, Takada K, Fukayama M: Downregulation of microrna-200 in ebv-associated gastric carcinoma. Cancer Res 2010;70:4719-4727.
-
(2010)
Cancer Res
, vol.70
, pp. 4719-4727
-
-
Shinozaki, A.1
Sakatani, T.2
Ushiku, T.3
Hino, R.4
Isogai, M.5
Ishikawa, S.6
Uozaki, H.7
Takada, K.8
Fukayama, M.9
-
14
-
-
0032146551
-
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
-
Iredale JP, Benyon RC, Pickering J, McCullen M, Northrop M, Pawley S, Hovell C, Arthur MJ: Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 1998;102:538-549.
-
(1998)
J Clin Invest
, vol.102
, pp. 538-549
-
-
Iredale, J.P.1
Benyon, R.C.2
Pickering, J.3
McCullen, M.4
Northrop, M.5
Pawley, S.6
Hovell, C.7
Arthur, M.J.8
-
15
-
-
0035835828
-
P27(kip1): Regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer
-
Philipp-Staheli J, Payne SR, Kemp CJ: P27(kip1): Regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer. Exp Cell Res 2001;264:148-168.
-
(2001)
Exp Cell Res
, vol.264
, pp. 148-168
-
-
Philipp-Staheli, J.1
Payne, S.R.2
Kemp, C.J.3
-
16
-
-
84872816163
-
Mir-138 inhibits tumor growth through repression of ezh2 in non-small cell lung cancer
-
Zhang H, Zhao M, Lv Z, Zhang X, Qin X, Wang H, Wang S, Su J, Lv X, Liu H, Du W, Zhou W, Chen X, Fei K: Mir-138 inhibits tumor growth through repression of ezh2 in non-small cell lung cancer. Cell Physiol Biochem 2013;31:56-65.
-
(2013)
Cell Physiol Biochem
, vol.31
, pp. 56-65
-
-
Zhang, H.1
Zhao, M.2
Lv, Z.3
Zhang, X.4
Qin, X.5
Wang, H.6
Wang, S.7
Su, J.8
Lv, X.9
Liu, H.10
Du, W.11
Zhou, W.12
Chen, X.13
Fei, K.14
-
17
-
-
84867401194
-
Epigenetic therapy with 3-deazaneplanocin a, an inhibitor of the histone methyltransferase ezh2, inhibits growth of non-small cell lung cancer cells
-
Kikuchi J, Takashina T, Kinoshita I, Kikuchi E, Shimizu Y, Sakakibara-Konishi J, Oizumi S, Marquez VE, Nishimura M, Dosaka-Akita H: Epigenetic therapy with 3-deazaneplanocin a, an inhibitor of the histone methyltransferase ezh2, inhibits growth of non-small cell lung cancer cells. Lung Cancer 2012;78:138-143.
-
(2012)
Lung Cancer
, vol.78
, pp. 138-143
-
-
Kikuchi, J.1
Takashina, T.2
Kinoshita, I.3
Kikuchi, E.4
Shimizu, Y.5
Sakakibara-Konishi, J.6
Oizumi, S.7
Marquez, V.E.8
Nishimura, M.9
Dosaka-Akita, H.10
-
18
-
-
84861328765
-
Ezh2 silencing with rnai enhances irradiation-induced inhibition of human lung cancer growth in vitro and in vivo
-
Xia H, Yu CH, Zhang Y, Yu J, Li J, Zhang W, Zhang B, Li Y, Guo N: Ezh2 silencing with rnai enhances irradiation-induced inhibition of human lung cancer growth in vitro and in vivo. Oncol Lett 2012;4:135-140.
-
(2012)
Oncol Lett
, vol.4
, pp. 135-140
-
-
Xia, H.1
Yu, C.H.2
Zhang, Y.3
Yu, J.4
Li, J.5
Zhang, W.6
Zhang, B.7
Li, Y.8
Guo, N.9
-
19
-
-
77956231521
-
Rnai targeting ezh2 inhibits tumor growth and liver metastasis of pancreatic cancer in vivo
-
Chen Y, Xie D, Yin Li W, Man Cheung C, Yao H, Chan CY, Xu FP, Liu YH, Sung JJ, Kung HF: Rnai targeting ezh2 inhibits tumor growth and liver metastasis of pancreatic cancer in vivo. Cancer Lett 2010;297:109-116.
-
(2010)
Cancer Lett
, vol.297
, pp. 109-116
-
-
Chen, Y.1
Xie, D.2
Yin Li, W.3
Man Cheung, C.4
Yao, H.5
Chan, C.Y.6
Xu, F.P.7
Liu, Y.H.8
Sung, J.J.9
Kung, H.F.10
-
20
-
-
77950874502
-
Comprehensive evaluation of the role of ezh2 in the growth, invasion, and aggression of a panel of prostate cancer cell lines
-
Karanikolas BD, Figueiredo ML, Wu L: Comprehensive evaluation of the role of ezh2 in the growth, invasion, and aggression of a panel of prostate cancer cell lines. Prostate 2010;70:675-688.
-
(2010)
Prostate
, vol.70
, pp. 675-688
-
-
Karanikolas, B.D.1
Figueiredo, M.L.2
Wu, L.3
-
21
-
-
58149214373
-
Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2
-
Ougolkov AV, Bilim VN, Billadeau DD: Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2. Clin Cancer Res 2008;14:6790-6796.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6790-6796
-
-
Ougolkov, A.V.1
Bilim, V.N.2
Billadeau, D.D.3
-
22
-
-
47249091921
-
The mir-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of e-cadherin transcriptional repressors zeb1 and zeb2
-
Korpal M, Lee ES, Hu G, Kang Y: The mir-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of e-cadherin transcriptional repressors zeb1 and zeb2. J Biol Chem 2008;283:14910-14914.
-
(2008)
J Biol Chem
, vol.283
, pp. 14910-14914
-
-
Korpal, M.1
Lee, E.S.2
Hu, G.3
Kang, Y.4
-
23
-
-
41649091906
-
The mir-200 family determines the epithelial phenotype of cancer cells by targeting the e-cadherin repressors zeb1 and zeb2
-
Park SM, Gaur AB, Lengyel E, Peter ME: The mir-200 family determines the epithelial phenotype of cancer cells by targeting the e-cadherin repressors zeb1 and zeb2. Genes Dev 2008;22:894-907.
-
(2008)
Genes Dev
, vol.22
, pp. 894-907
-
-
Park, S.M.1
Gaur, A.B.2
Lengyel, E.3
Peter, M.E.4
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