HPW-RX40 restores anoikis sensitivity of human breast cancer cells by inhibiting integrin/FAK signaling

Toxicology and Applied Pharmacology

Volumn 289, Issue 2, 2015, Pages 330-340

  Chen, I Hua ^a   Shih, Hsin Chu ^a   Hsieh, Pei Wen ^b   Chang, Fang Rong ^a,c   Wu, Yang Chang ^d   Wu, Chin Chung ^a,e  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Anoikis; Breast cancer; FAK; Integrin; Metastasis; Nitrostyrene

Indexed keywords

2 METHOXY 4 (2 NITROVINYL)PHENYL 2,3 DICHLOROBENZOATE; ANTINEOPLASTIC AGENT; BETA1 INTEGRIN; DOXORUBICIN; FOCAL ADHESION KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PAXILLIN; PROTEIN BCL 2; STEROID RECEPTOR COACTIVATOR 1; STYRENE DERIVATIVE; UNCLASSIFIED DRUG; 2-METHOXY-4-(2-NITROVINYL)PHENYL 2,3-DICHLOROBENZOATE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; APOPTOSIS REGULATORY PROTEIN; CHLOROBENZOIC ACID DERIVATIVE; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; FOCAL ADHESION KINASE 1; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PTK2 PROTEIN, HUMAN; PXN PROTEIN, HUMAN; QUINAZOLINE DERIVATIVE; TYRPHOSTIN;

ANOIKIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL ADHESION; CELL AGGREGATION; CELL DEATH; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; METASTASIS; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; FEMALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

ANOIKIS; ANTIGENS, CD29; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS REGULATORY PROTEINS; BREAST NEOPLASMS; CELL ADHESION; CELL AGGREGATION; CELL LINE, TUMOR; CHLOROBENZOATES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; FOCAL ADHESION KINASE 1; HUMANS; PAXILLIN; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STYRENES; TYRPHOSTINS;

EID: 84949229717     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.09.011     Document Type: Article

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