Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells

Cancer Research

Volumn 61, Issue 19, 2001, Pages 7079-7090

  Hauck, Christof R ^a   Sieg, David J ^a   Hsia, Datsun A ^a   Loftus, Joseph C ^b   Gaarde, William A ^c   Monia, Brett P ^c   Schlaepfer, David D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b MAYO CLINIC   (United States)

^c ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTISENSE OLIGONUCLEOTIDE; BATIMASTAT; EPIDERMAL GROWTH FACTOR; FOCAL ADHESION KINASE; GELATINASE B; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE P60; PROTEIN P130; STRESS ACTIVATED PROTEIN KINASE; TYROSINE;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CARCINOMA CELL; CELL CULTURE; CELL INVASION; CELL MIGRATION; CELL MOTILITY; COMPLEX FORMATION; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; FIBROBLAST; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; CELL MOVEMENT; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; TUMOR CELLS, CULTURED;

EID: 0035476836     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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