Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells

Oncogene

Volumn 23, Issue 22, 2004, Pages 3962-3971

  Hecker, Timothy P ^a,b   Ding, Qiang ^a   Rege, Tanya A ^a,b,c   Hanks, Steven K ^d   Gladson, Candece L ^a,b,c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Astrocytoma; Focal adhesion kinase (FAK); Glioblastoma; Glioma; Proliferation; Ras; RasGAP

Indexed keywords

FOCAL ADHESION KINASE; MUTANT PROTEIN; PROTEIN P120; RAS PROTEIN; VITRONECTIN; FOCAL ADHESION KINASE 1; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; PROTEIN TYROSINE KINASE; PTK2 PROTEIN, HUMAN; PTK2 PROTEIN, RAT;

ARTICLE; ASTROCYTOMA CELL; BRAIN; CANCER CELL CULTURE; CELL AGGREGATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MALIGNANT NEOPLASTIC DISEASE; MONOLAYER CULTURE; MUTATION; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUSPENSION CELL CULTURE; TUMOR BIOPSY; ANIMAL; ASTROCYTOMA; CELL DIVISION; METABOLISM; PHYSIOLOGY; RAT;

ANIMALS; ASTROCYTOMA; CELL DIVISION; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GUANOSINE TRIPHOSPHATE; HUMANS; P120 GTPASE ACTIVATING PROTEIN; PROTEIN-TYROSINE KINASES; RAS PROTEINS; RATS;

EID: 2542511549     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207541     Document Type: Article

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