Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR Activation

Structure

Volumn 23, Issue 12, 2015, Pages 2349-2357

  Diebolder, Christoph A ^a,b   Halff, Els F ^b,c   Koster, Abraham J ^a   Huizinga, Eric G ^b   Koning, Roman I ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSOME; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CYCLIC GMP; CYCLIC GUANOSINE MONOPHOSPHATE DEPENDENT PROTEIN KINASE 1 ALPHA; FLAGELLIN; INFLAMMASOME; MULTIPROTEIN COMPLEX; NAIP5 PROTEIN; NLRC4 PROTEIN; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CALCIUM BINDING PROTEIN; IPAF PROTEIN, MOUSE; NAIP5 PROTEIN, MOUSE; NEURONAL APOPTOSIS INHIBITORY PROTEIN;

ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DENSITY; ELECTRON TOMOGRAPHY; EMBRYO; ENZYME ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; MOUSE; MURINE; NONHUMAN; OLIGOMERIZATION; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; STRUCTURE ANALYSIS; SURFACE PROPERTY; ANIMAL; CHEMISTRY; CRYOELECTRON MICROSCOPY; HEK293 CELL LINE; METABOLISM;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM-BINDING PROTEINS; CRYOELECTRON MICROSCOPY; ELECTRON MICROSCOPE TOMOGRAPHY; HEK293 CELLS; HUMANS; INFLAMMASOMES; MICE; NEURONAL APOPTOSIS-INHIBITORY PROTEIN;

EID: 84949201317     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2015.10.001     Document Type: Article

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