-
1
-
-
84890550163
-
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
-
Arpaia N., Campbell C., Fan X., Dikiy S., van der Veeken J., deRoos P., et al. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature 2013, 504(7480):451-455.
-
(2013)
Nature
, vol.504
, Issue.7480
, pp. 451-455
-
-
Arpaia, N.1
Campbell, C.2
Fan, X.3
Dikiy, S.4
van der Veeken, J.5
deRoos, P.6
-
2
-
-
46149098344
-
LXR signaling couples sterol metabolism to proliferation in the acquired immune response
-
Bensinger S.J., Bradley M.N., Joseph S.B., Zelcer N., Janssen E.M., Hausner M.A., Shih R., Parks J.S., Edwards P.A., Jamieson B.D., Tontonoz P. LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell 2008, 134:97-111.
-
(2008)
Cell
, vol.134
, pp. 97-111
-
-
Bensinger, S.J.1
Bradley, M.N.2
Joseph, S.B.3
Zelcer, N.4
Janssen, E.M.5
Hausner, M.A.6
Shih, R.7
Parks, J.S.8
Edwards, P.A.9
Jamieson, B.D.10
Tontonoz, P.11
-
3
-
-
84922080059
-
De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
-
Berod L., Friedrich C., Nandan A., et al. De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells. Nat. Med. 2014, 20(11):1327-1333.
-
(2014)
Nat. Med.
, vol.20
, Issue.11
, pp. 1327-1333
-
-
Berod, L.1
Friedrich, C.2
Nandan, A.3
-
5
-
-
84921309472
-
The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo
-
Blagih J., Coulombe F., Vincent E.E., et al. The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo. Immunity 2015, 42(1):41-54.
-
(2015)
Immunity
, vol.42
, Issue.1
, pp. 41-54
-
-
Blagih, J.1
Coulombe, F.2
Vincent, E.E.3
-
6
-
-
84925969707
-
Metabolic pathways promoting cancer cell survival and growth
-
Boroughs L.K., DeBerardinis R.J. Metabolic pathways promoting cancer cell survival and growth. Nat. Cell Biol. 2015, 17(4):351-359.
-
(2015)
Nat. Cell Biol.
, vol.17
, Issue.4
, pp. 351-359
-
-
Boroughs, L.K.1
DeBerardinis, R.J.2
-
7
-
-
84920518692
-
Autophagy in T-cell development, activation and differentiation
-
Bronietzki A.W., Schuster M., Schmitz I. Autophagy in T-cell development, activation and differentiation. Immunol. Cell Biol. 2015, 93(January (1)):25-34.
-
(2015)
Immunol. Cell Biol.
, vol.93
, Issue.JANUARY 1
, pp. 25-34
-
-
Bronietzki, A.W.1
Schuster, M.2
Schmitz, I.3
-
9
-
-
84905510173
-
Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells
-
Cao Y., Rathmell J.C., Macintyre A.N. Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. PLoS One 2014, 9(8).
-
(2014)
PLoS One
, vol.9
, Issue.8
-
-
Cao, Y.1
Rathmell, J.C.2
Macintyre, A.N.3
-
10
-
-
77955475969
-
Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation
-
Carr E.L., Kelman A., Wu G.S., Gopaul R., Senkevitch E., Aghvanyan A., et al. Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation. J. Immunol. 2010, 185:1037-1044.
-
(2010)
J. Immunol.
, vol.185
, pp. 1037-1044
-
-
Carr, E.L.1
Kelman, A.2
Wu, G.S.3
Gopaul, R.4
Senkevitch, E.5
Aghvanyan, A.6
-
12
-
-
84878831880
-
Posttranscriptional control of T cell effector function by aerobic glycolysis
-
Chang C.H., Curtis J.D., Maggi L.B., Faubert B., Villarino A.V., O'Sullivan D., et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 2013, 153(June (6)):1239-1251.
-
(2013)
Cell
, vol.153
, Issue.JUNE 6
, pp. 1239-1251
-
-
Chang, C.H.1
Curtis, J.D.2
Maggi, L.B.3
Faubert, B.4
Villarino, A.V.5
O'Sullivan, D.6
-
13
-
-
84860237060
-
Regulation and function of mTOR signalling in T cell fate decisions
-
Chi H. Regulation and function of mTOR signalling in T cell fate decisions. Nat. Rev. Immunol. 2012, 12:325-338.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 325-338
-
-
Chi, H.1
-
15
-
-
80052277906
-
Control of T(H) 17/T(reg) balance by hypoxia-inducible factor 1
-
Dang E.V., Barbi J., Yang H.Y., Jinasena D., Yu H., Zheng Y., et al. Control of T(H) 17/T(reg) balance by hypoxia-inducible factor 1. Cell 2011, 146:772-784.
-
(2011)
Cell
, vol.146
, pp. 772-784
-
-
Dang, E.V.1
Barbi, J.2
Yang, H.Y.3
Jinasena, D.4
Yu, H.5
Zheng, Y.6
-
16
-
-
84860512005
-
Links between metabolism and cancer
-
Dang C.V. Links between metabolism and cancer. Genes Dev. 2012, 26(May (9)):877-890.
-
(2012)
Genes Dev.
, vol.26
, Issue.MAY 9
, pp. 877-890
-
-
Dang, C.V.1
-
17
-
-
75149148563
-
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
-
DeBerardinis R.J., Cheng T. Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer. Oncogene 2010, 29(January (3)):313-324.
-
(2010)
Oncogene
, vol.29
, Issue.JANUARY 3
, pp. 313-324
-
-
DeBerardinis, R.J.1
Cheng, T.2
-
18
-
-
84922362257
-
Sugar, fat, and protein: new insights into what T cells crave
-
Delgoffe G.M., Powell J.D. Sugar, fat, and protein: new insights into what T cells crave. Curr. Opin. Immunol. 2015, 33(April):49-54.
-
(2015)
Curr. Opin. Immunol.
, vol.33
, Issue.APRIL
, pp. 49-54
-
-
Delgoffe, G.M.1
Powell, J.D.2
-
19
-
-
79952985551
-
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
-
Delgoffe G.M., et al. The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. Nat. Immunol. 2011, 12:295-303.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 295-303
-
-
Delgoffe, G.M.1
-
20
-
-
84857716739
-
Multiple biological activities of lactic acid in cancer: influences on tumor growth, angiogenesis and metastasis
-
Dhup S., Dadhich R.K., Porporato P.E., Sonveaux P. Multiple biological activities of lactic acid in cancer: influences on tumor growth, angiogenesis and metastasis. Curr. Pharm. Des. 2012, 18(10):1319-1330.
-
(2012)
Curr. Pharm. Des.
, vol.18
, Issue.10
, pp. 1319-1330
-
-
Dhup, S.1
Dadhich, R.K.2
Porporato, P.E.3
Sonveaux, P.4
-
21
-
-
79955579989
-
The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon
-
Donohoe D.R., Garge N., Zhang X., Sun W., O'Connell T.M., Bunger M.K., Bultman S.J. The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab. 2011, 13(5):517-526.
-
(2011)
Cell Metab.
, vol.13
, Issue.5
, pp. 517-526
-
-
Donohoe, D.R.1
Garge, N.2
Zhang, X.3
Sun, W.4
O'Connell, T.M.5
Bunger, M.K.6
Bultman, S.J.7
-
22
-
-
79151486083
-
Metabolism, migration and memory in cytotoxic T cells
-
Finlay D., Cantrell D.A. Metabolism, migration and memory in cytotoxic T cells. Nat. Rev. Immunol. 2011, 11:109-117.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 109-117
-
-
Finlay, D.1
Cantrell, D.A.2
-
23
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
Frauwirth K., Riley J., Harris M., Parry R., Rathmell J., Plas D., et al. The CD28 signaling pathway regulates glucose metabolism. Immunity 2002, 16:769-777.
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.1
Riley, J.2
Harris, M.3
Parry, R.4
Rathmell, J.5
Plas, D.6
-
24
-
-
84890564250
-
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
-
Furusawa Y., Obata Y., Fukuda S., Endo T.A., Nakato G., Takahashi D., et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 2013, 504(December (7480)):446-450.
-
(2013)
Nature
, vol.504
, Issue.DECEMBER 7480
, pp. 446-450
-
-
Furusawa, Y.1
Obata, Y.2
Fukuda, S.3
Endo, T.A.4
Nakato, G.5
Takahashi, D.6
-
25
-
-
79251500689
-
Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease
-
ra8
-
Gatza E., Wahl D.R., Opipari A.W., Sundberg T.B., Reddy P., Liu C., et al. Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease. Sci. Transl. Med. 2011, 3(67):67ra8.
-
(2011)
Sci. Transl. Med.
, vol.3
, Issue.67
, pp. 67
-
-
Gatza, E.1
Wahl, D.R.2
Opipari, A.W.3
Sundberg, T.B.4
Reddy, P.5
Liu, C.6
-
26
-
-
84859140799
-
Metabolic pathways in T cell fate and function
-
Gerriets V.A., Rathmell J.C. Metabolic pathways in T cell fate and function. Trends Immunol. 2012, 33(4):168-173.
-
(2012)
Trends Immunol.
, vol.33
, Issue.4
, pp. 168-173
-
-
Gerriets, V.A.1
Rathmell, J.C.2
-
28
-
-
84904173553
-
Metabolism of stromal and immune cells in health and disease
-
Ghesquiere B., Wong B.W., Kuchnio A., Carmeliet P. Metabolism of stromal and immune cells in health and disease. Nature 2014, 511:167-176.
-
(2014)
Nature
, vol.511
, pp. 167-176
-
-
Ghesquiere, B.1
Wong, B.W.2
Kuchnio, A.3
Carmeliet, P.4
-
29
-
-
4043110513
-
Lactate metabolism: a new paradigm for the third millennium
-
Gladden L.B. Lactate metabolism: a new paradigm for the third millennium. J. Physiol. 2004, 558(Pt 1):5-30.
-
(2004)
J. Physiol.
, vol.558
, pp. 5-30
-
-
Gladden, L.B.1
-
30
-
-
3142696783
-
The mitogen-induced increase in T cell size involves PKC and NFAT activation of Rel/NF-kappaB-dependent c-myc expression
-
Grumont R., Lock P., Mollinari M., Shannon F.M., Moore A., Gerondakis S. The mitogen-induced increase in T cell size involves PKC and NFAT activation of Rel/NF-kappaB-dependent c-myc expression. Immunity 2004, 21:19-30.
-
(2004)
Immunity
, vol.21
, pp. 19-30
-
-
Grumont, R.1
Lock, P.2
Mollinari, M.3
Shannon, F.M.4
Moore, A.5
Gerondakis, S.6
-
31
-
-
84872348186
-
Macroautophagy in T lymphocyte development and function
-
He M.X., McLeod I.X., Jia W., He Y.W. Macroautophagy in T lymphocyte development and function. Front. Immunol. 2012, 3(Feb):22.
-
(2012)
Front. Immunol.
, vol.3
, Issue.FEB
, pp. 22
-
-
He, M.X.1
McLeod, I.X.2
Jia, W.3
He, Y.W.4
-
32
-
-
52649107626
-
Cancer cell metabolism: Warburg and beyond
-
Hsu P.P., Sabatini D.M. Cancer cell metabolism: Warburg and beyond. Cell 2008, 134(5):703-707.
-
(2008)
Cell
, vol.134
, Issue.5
, pp. 703-707
-
-
Hsu, P.P.1
Sabatini, D.M.2
-
33
-
-
44449165597
-
Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways
-
Jacobs S.R., Herman C.E., MacIver N.J., Wofford J.A., Wieman H.L., Hammen J.J., et al. Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. J. Immunol. 2008, 180:4476-4486.
-
(2008)
J. Immunol.
, vol.180
, pp. 4476-4486
-
-
Jacobs, S.R.1
Herman, C.E.2
MacIver, N.J.3
Wofford, J.A.4
Wieman, H.L.5
Hammen, J.J.6
-
34
-
-
84928771999
-
T cell exclusion, immune privilege, and the tumor microenvironment
-
Joyce J.A., Fearon D.T. T cell exclusion, immune privilege, and the tumor microenvironment. Science 2015, 348(6230):74-80.
-
(2015)
Science
, vol.348
, Issue.6230
, pp. 74-80
-
-
Joyce, J.A.1
Fearon, D.T.2
-
36
-
-
84876684375
-
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
-
Kidani Y., Elsaesser H., Hock M.B., Vergnes L., Williams K.J., Argus J.P., et al. Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat. Immunol. 2013, 14:489-499.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 489-499
-
-
Kidani, Y.1
Elsaesser, H.2
Hock, M.B.3
Vergnes, L.4
Williams, K.J.5
Argus, J.P.6
-
37
-
-
4744359216
-
Arginine and cancer
-
Lind D.S. Arginine and cancer. J. Nutr. 2004, 134(Suppl. 10):2837S-2841S.
-
(2004)
J. Nutr.
, vol.134
, pp. 2837S-2841S
-
-
Lind, D.S.1
-
38
-
-
67649432744
-
Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees
-
Lob S., Konigsrainer A. Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees. Nat. Rev. Cancer 2009, 9(6):445-452.
-
(2009)
Nat. Rev. Cancer
, vol.9
, Issue.6
, pp. 445-452
-
-
Lob, S.1
Konigsrainer, A.2
-
39
-
-
84964267895
-
Fatty acid metabolism in the regulation of T cell function
-
Lochner M., Berod L., Sparwasser T. Fatty acid metabolism in the regulation of T cell function. Trends Immune. 2015, 36(2):81-91.
-
(2015)
Trends Immune.
, vol.36
, Issue.2
, pp. 81-91
-
-
Lochner, M.1
Berod, L.2
Sparwasser, T.3
-
41
-
-
84904057246
-
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function
-
Macintyre A.N., Gerriets V.A., Nichols A.G., et al. The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function. Cell Metab. 2014, 20(July (1)):61-72.
-
(2014)
Cell Metab.
, vol.20
, Issue.JULY 1
, pp. 61-72
-
-
Macintyre, A.N.1
Gerriets, V.A.2
Nichols, A.G.3
-
42
-
-
84930576092
-
Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α
-
Mascanfroni I.D., Takenaka M.C., Yeste, et al. Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α. Nat. Med. 2015, 21(6):638-646.
-
(2015)
Nat. Med.
, vol.21
, Issue.6
, pp. 638-646
-
-
Mascanfroni, I.D.1
Takenaka, M.C.2
Yeste3
-
43
-
-
84919903877
-
Acetate is a bioenergetic substrate for human glioblastoma and brain metastases
-
Mashimo T., Pichumani K., Vemireddy V., Hatanpaa K.J., Singh D.K., Sirasanagandla S., et al. Acetate is a bioenergetic substrate for human glioblastoma and brain metastases. Cell 2014, 159(December (7)):1603-1614.
-
(2014)
Cell
, vol.159
, Issue.DECEMBER 7
, pp. 1603-1614
-
-
Mashimo, T.1
Pichumani, K.2
Vemireddy, V.3
Hatanpaa, K.J.4
Singh, D.K.5
Sirasanagandla, S.6
-
44
-
-
84923186422
-
Famine versus feast: understanding the metabolism of tumors in vivo
-
Mayers J.R., Vander Heiden M.G. Famine versus feast: understanding the metabolism of tumors in vivo. Trends Biochem. Sci. 2015, 40(3):130-140.
-
(2015)
Trends Biochem. Sci.
, vol.40
, Issue.3
, pp. 130-140
-
-
Mayers, J.R.1
Vander Heiden, M.G.2
-
45
-
-
59149090614
-
Monocarboxylate transporters: past, present, and future
-
Merezhinskaya N., Fishbein W.N. Monocarboxylate transporters: past, present, and future. Histol. Histopathol. 2009, 24(2):243-264.
-
(2009)
Histol. Histopathol.
, vol.24
, Issue.2
, pp. 243-264
-
-
Merezhinskaya, N.1
Fishbein, W.N.2
-
46
-
-
84873459097
-
Understanding metabolic regulation and its influence on cell physiology
-
Metallo C.M., Vander Heiden M.G. Understanding metabolic regulation and its influence on cell physiology. Mol. Cell. 2013, 49:388-398.
-
(2013)
Mol. Cell.
, vol.49
, pp. 388-398
-
-
Metallo, C.M.1
Vander Heiden, M.G.2
-
48
-
-
84928056873
-
The journey from discoveries in fundamental immunology to cancer immunotherapy
-
Miller J., Sadelain M. The journey from discoveries in fundamental immunology to cancer immunotherapy. Cancer Cell 2015, 27(4):439-449.
-
(2015)
Cancer Cell
, vol.27
, Issue.4
, pp. 439-449
-
-
Miller, J.1
Sadelain, M.2
-
49
-
-
34248173331
-
Indoleamine 2,3-dioxygenase and tumor-induced tolerance
-
Munn D.H., Mellor A.L. Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J. Clin. Invest. 2007, 117(5):1147-1154.
-
(2007)
J. Clin. Invest.
, vol.117
, Issue.5
, pp. 1147-1154
-
-
Munn, D.H.1
Mellor, A.L.2
-
50
-
-
84925545111
-
Clinical blockade of PD1 and LAG3-potential mechanisms of action
-
Nguyen Lt., Ohashi Ps. Clinical blockade of PD1 and LAG3-potential mechanisms of action. Nat. Rev. Immunol. 2015, 15(1):45-56.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, Issue.1
, pp. 45-56
-
-
Nguyen, L.1
Ohashi, P.2
-
51
-
-
59049087460
-
Bidirectional transport of amino acids regulates mTOR and autophagy
-
Nicklin P., Bergman P., Zhang B., Triantafellow E., Wang H., Nyfeler B., et al. Bidirectional transport of amino acids regulates mTOR and autophagy. Cell 2009, 136(February (3)):521-534.
-
(2009)
Cell
, vol.136
, Issue.FEBRUARY 3
, pp. 521-534
-
-
Nicklin, P.1
Bergman, P.2
Zhang, B.3
Triantafellow, E.4
Wang, H.5
Nyfeler, B.6
-
52
-
-
84904392273
-
+ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development
-
+ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development. Immunity 2014, 41(July (1)):75-88.
-
(2014)
Immunity
, vol.41
, Issue.JULY 1
, pp. 75-88
-
-
O'Sullivan, D.1
van der Windt, G.J.2
Huang, S.C.3
-
53
-
-
84961290082
-
Targeting T. cell metabolism for therapy
-
O'sullivan D., Pearce E.L. Targeting T. cell metabolism for therapy. Trends Immunol. 2015, 36(2):71-80.
-
(2015)
Trends Immunol.
, vol.36
, Issue.2
, pp. 71-80
-
-
O'sullivan, D.1
Pearce, E.L.2
-
54
-
-
84930671843
-
+ T cell immunity through effects on mitochondrial respiration
-
+ T cell immunity through effects on mitochondrial respiration. Science 2015, 348(6238):995-1001.
-
(2015)
Science
, vol.348
, Issue.6238
, pp. 995-1001
-
-
Okoye, I.1
Wang, L.2
Pallmer, K.3
-
55
-
-
84856687289
-
The role of low-level lactate production in airway inflammation in asthma
-
Ostroukhova M., Goplen N., Karim M.Z., Michalec L., Guo L., Liang Q., et al. The role of low-level lactate production in airway inflammation in asthma. Am. J. Physiol. Lung Cell. Mol. Physiol. 2012, 302(3):L300-L307.
-
(2012)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.302
, Issue.3
, pp. L300-L307
-
-
Ostroukhova, M.1
Goplen, N.2
Karim, M.Z.3
Michalec, L.4
Guo, L.5
Liang, Q.6
-
56
-
-
27144496045
-
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
-
Parry R.V., Chemnitz J.M., Frauwirth K.A., et al. CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms. Mol. Cell Biol. 2005, 25(November (21)):9543-9553.
-
(2005)
Mol. Cell Biol.
, vol.25
, Issue.NOVEMBER 21
, pp. 9543-9553
-
-
Parry, R.V.1
Chemnitz, J.M.2
Frauwirth, K.A.3
-
57
-
-
84925688346
-
PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
-
Patsoukis N., Bardhan K., Chatterjee P., et al. PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation. Nat. Commun. 2015, 26(6):6692.
-
(2015)
Nat. Commun.
, vol.26
, Issue.6
, pp. 6692
-
-
Patsoukis, N.1
Bardhan, K.2
Chatterjee, P.3
-
58
-
-
84885670616
-
Fueling immunity: insights into metabolism and lymphocyte function
-
Pearce E.L., Poffenberger M.C., Chang C.H., Jones R.G. Fueling immunity: insights into metabolism and lymphocyte function. Science 2013, 342:1242454.
-
(2013)
Science
, vol.342
, pp. 1242454
-
-
Pearce, E.L.1
Poffenberger, M.C.2
Chang, C.H.3
Jones, R.G.4
-
59
-
-
78049287331
-
MTOR signalling and metabolic regulation of T cell differentiation
-
Peter C., Waldmann H., Cobbold S.P. mTOR signalling and metabolic regulation of T cell differentiation. Curr. Opin. Immunol. 2010, 22:655-661.
-
(2010)
Curr. Opin. Immunol.
, vol.22
, pp. 655-661
-
-
Peter, C.1
Waldmann, H.2
Cobbold, S.P.3
-
60
-
-
31044433796
-
Lactate-a signal coordinating cell and systemic function
-
Philp A., Macdonald A.L., Watt P.W. Lactate-a signal coordinating cell and systemic function. J. Exp. Biol. 2005, 208(Pt 24):4561-4575.
-
(2005)
J. Exp. Biol.
, vol.208
, pp. 4561-4575
-
-
Philp, A.1
Macdonald, A.L.2
Watt, P.W.3
-
61
-
-
84857136779
-
Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase
-
Pilotte L., Larrieu P., Proc Natl Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase. Acad. Sci. U. S. A. 2012, 109(7):2497-2502.
-
(2012)
Acad. Sci. U. S. A.
, vol.109
, Issue.7
, pp. 2497-2502
-
-
Pilotte, L.1
Larrieu, P.2
Proc, Natl3
-
62
-
-
82755160805
-
Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27
-
Pot C., Apetoh L., Awasthi A., Kuchroo V.K. Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27. Semin. Immunol. 2011, 23(6):438-445.
-
(2011)
Semin. Immunol.
, vol.23
, Issue.6
, pp. 438-445
-
-
Pot, C.1
Apetoh, L.2
Awasthi, A.3
Kuchroo, V.K.4
-
63
-
-
79951892537
-
The human serum metabolome
-
Psychogios N., Hau D.D., Peng J., Guo A.C., Mandal R., Bouatra S., et al. The human serum metabolome. PLoS One 2011, 6(2):e16957.
-
(2011)
PLoS One
, vol.6
, Issue.2
-
-
Psychogios, N.1
Hau, D.D.2
Peng, J.3
Guo, A.C.4
Mandal, R.5
Bouatra, S.6
-
65
-
-
84858758766
-
Adoptive immunotherapy for cancer: harnessing the T cell response
-
Restifo N.P., Dudley M.E., Rosenberg S.A. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat. Rev. Immunol. 2012, 12(March (3)):269-281.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, Issue.MARCH 3
, pp. 269-281
-
-
Restifo, N.P.1
Dudley, M.E.2
Rosenberg, S.A.3
-
66
-
-
0025826956
-
Regulation of interleukin 2 production, interleukin 2 mRNA expression and intracellular glutathione levels in ex vivo derived T lymphocytes by lactate
-
Roth S., Droge W. Regulation of interleukin 2 production, interleukin 2 mRNA expression and intracellular glutathione levels in ex vivo derived T lymphocytes by lactate. Eur. J. Immunol. 1991, 21(8):1933-1937.
-
(1991)
Eur. J. Immunol.
, vol.21
, Issue.8
, pp. 1933-1937
-
-
Roth, S.1
Droge, W.2
-
67
-
-
0025740787
-
Regulation of intracellular glutathione levels and lymphocyte functions by lactate
-
Roth S., Gmunder H., Droge W. Regulation of intracellular glutathione levels and lymphocyte functions by lactate. Cell. Immunol. 1991, 136(1):95-104.
-
(1991)
Cell. Immunol.
, vol.136
, Issue.1
, pp. 95-104
-
-
Roth, S.1
Gmunder, H.2
Droge, W.3
-
68
-
-
84891708632
-
B Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality
-
Saha A., Aoyama K., Taylor P.A., et al. B Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality. Blood 2013, 122(7):3062-3073.
-
(2013)
Blood
, vol.122
, Issue.7
, pp. 3062-3073
-
-
Saha, A.1
Aoyama, K.2
Taylor, P.A.3
-
70
-
-
84928774156
-
The future of immune checkpoint therapy
-
Sharma P., Allison J.P. The future of immune checkpoint therapy. Science 2015, 348(April (6230)):56-61.
-
(2015)
Science
, vol.348
, Issue.APRIL 6230
, pp. 56-61
-
-
Sharma, P.1
Allison, J.P.2
-
71
-
-
79960369458
-
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
Shi L.Z., Wang R., Huang G., Vogel P., Neale G., Green D.R., Chi H. HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. J. Exp. Med. 2011, 208:1367-1376.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1367-1376
-
-
Shi, L.Z.1
Wang, R.2
Huang, G.3
Vogel, P.4
Neale, G.5
Green, D.R.6
Chi, H.7
-
72
-
-
47249118348
-
Tumor-secreted lactic acid promotes IL-23/IL-17 proinflammatory pathway
-
Shime H., Yabu M., Akazawa T., Kodama K., Matsumoto M., Seya T., et al. Tumor-secreted lactic acid promotes IL-23/IL-17 proinflammatory pathway. J. Immunol. 2008, 180(11):7175-7183.
-
(2008)
J. Immunol.
, vol.180
, Issue.11
, pp. 7175-7183
-
-
Shime, H.1
Yabu, M.2
Akazawa, T.3
Kodama, K.4
Matsumoto, M.5
Seya, T.6
-
73
-
-
84923207192
-
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia
-
Erratum in: Cancer Metab. 2014; 2: 22
-
Shukla S.K., Gebregiworgis T., Purohit V., Chaika N.V., Gunda V., Radhakrishnan P., et al. Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia. Cancer Metab. 2014, 2(September (1)):18. Erratum in: Cancer Metab. 2014; 2: 22.
-
(2014)
Cancer Metab.
, vol.2
, pp. 18
-
-
Shukla, S.K.1
Gebregiworgis, T.2
Purohit, V.3
Chaika, N.V.4
Gunda, V.5
Radhakrishnan, P.6
-
74
-
-
84926514026
-
T cell metabolic fitness in antitumor immunity
-
Siska P.J., Rathmell J.C. T cell metabolic fitness in antitumor immunity. Trends Immunol. 2015, 36(4):257-264.
-
(2015)
Trends Immunol.
, vol.36
, Issue.4
, pp. 257-264
-
-
Siska, P.J.1
Rathmell, J.C.2
-
75
-
-
0027938204
-
Demonstration of organic anion transport in T lymphocytes. l-Lactate and fluo-3 are target molecules
-
Sommer F., Bischof S., Rollinghoff M., Lohoff M. Demonstration of organic anion transport in T lymphocytes. l-Lactate and fluo-3 are target molecules. J. Immunol. 1994, 153(8):3523-3532.
-
(1994)
J. Immunol.
, vol.153
, Issue.8
, pp. 3523-3532
-
-
Sommer, F.1
Bischof, S.2
Rollinghoff, M.3
Lohoff, M.4
-
76
-
-
84907228811
-
Metformin attenuates experimental autoimmune arthritis through reciprocal regulation of Th17/Treg balance and osteoclastogenesis
-
(Epub August 20)
-
Son H.J., Lee J., Lee S.Y., et al. Metformin attenuates experimental autoimmune arthritis through reciprocal regulation of Th17/Treg balance and osteoclastogenesis. Mediators Inflamm. 2014, 2014:973986. (Epub August 20).
-
(2014)
Mediators Inflamm.
, vol.2014
-
-
Son, H.J.1
Lee, J.2
Lee, S.Y.3
-
77
-
-
75149123468
-
Ostrand-Rosenberg Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine
-
Srivastava M.K., Sinha P., Clements V.K., Rodriguez P., Ostrand-Rosenberg Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer 2010, 70(1):6.
-
(2010)
Cancer
, vol.70
, Issue.1
, pp. 6
-
-
Srivastava, M.K.1
Sinha, P.2
Clements, V.K.3
Rodriguez, P.4
-
78
-
-
84928062583
-
Immune checkpoint blockade: a common denominator approach to cancer therapy
-
Topalian S.L., Drake C.G., Pardoll D.M. Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell 2015, 27(April (4)):450-461.
-
(2015)
Cancer Cell
, vol.27
, Issue.APRIL 4
, pp. 450-461
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
79
-
-
0037383806
-
+ T lymphocyte responses
-
+ T lymphocyte responses. Nat. Immunol. 2003, 4(4):361-365.
-
(2003)
Nat. Immunol.
, vol.4
, Issue.4
, pp. 361-365
-
-
van Stipdonk, M.J.1
-
80
-
-
84865285455
-
Metabolic switching and fuel choice during T-cell differentiation and memory development
-
van der Windt G.J., Pearce E.L. Metabolic switching and fuel choice during T-cell differentiation and memory development. Immunol. Rev. 2013, 249:27-42.
-
(2013)
Immunol. Rev.
, vol.249
, pp. 27-42
-
-
van der Windt, G.J.1
Pearce, E.L.2
-
81
-
-
84865294745
-
Metabolic reprogramming and metabolic dependency in T cells
-
Wang R., Green D.R. Metabolic reprogramming and metabolic dependency in T cells. Immunol. Rev. 2012, 249:14-26.
-
(2012)
Immunol. Rev.
, vol.249
, pp. 14-26
-
-
Wang, R.1
Green, D.R.2
-
82
-
-
84860800305
-
The immune diet: meeting the metabolic demands of lymphocyte activation. F1000
-
Wang R., Green D.R. The immune diet: meeting the metabolic demands of lymphocyte activation. F1000. Biol. Rep. 2012, 4:9.
-
(2012)
Biol. Rep.
, vol.4
, pp. 9
-
-
Wang, R.1
Green, D.R.2
-
83
-
-
84866562625
-
Metabolic checkpoints in activated T cells
-
Wang R., Green D.R. Metabolic checkpoints in activated T cells. Nat. Immunol. 2012, 13:907-915.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 907-915
-
-
Wang, R.1
Green, D.R.2
-
84
-
-
84255199079
-
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
-
Wang R., Dillon Christopher P., Shi Lewis Z., Milasta S., Carter R., Finkelstein D., et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 2011, 35:871-882.
-
(2011)
Immunity
, vol.35
, pp. 871-882
-
-
Wang, R.1
Dillon Christopher, P.2
Shi Lewis, Z.3
Milasta, S.4
Carter, R.5
Finkelstein, D.6
-
85
-
-
84905673351
-
The intercellular metabolic interplay between tumor and immune cells
-
Wang T., Liu G., Wang R. The intercellular metabolic interplay between tumor and immune cells. Front. Immunol. 2014, 5:358.
-
(2014)
Front. Immunol.
, vol.5
, pp. 358
-
-
Wang, T.1
Liu, G.2
Wang, R.3
-
86
-
-
0001221508
-
On respiratory impairment in cancer cells
-
Warburg O. On respiratory impairment in cancer cells. Science 1956, 124:269-270.
-
(1956)
Science
, vol.124
, pp. 269-270
-
-
Warburg, O.1
-
87
-
-
84924975551
-
Mitochondria in the regulation of innate and adaptive immunity
-
Weinberg S.E., Sena L.A., Chandel N.S. Mitochondria in the regulation of innate and adaptive immunity. Immunity 2015, 42(3):406-417.
-
(2015)
Immunity
, vol.42
, Issue.3
, pp. 406-417
-
-
Weinberg, S.E.1
Sena, L.A.2
Chandel, N.S.3
-
88
-
-
58849092225
-
Epigenetic control of T-helper-cell differentiation
-
Wilson C.B., Rowell E., Sekimata M. Epigenetic control of T-helper-cell differentiation. Nat. Rev. Immunol. 2009, 9(February (2)):91-105.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, Issue.FEBRUARY 2
, pp. 91-105
-
-
Wilson, C.B.1
Rowell, E.2
Sekimata, M.3
-
89
-
-
77955281020
-
Glutamine addiction: a new therapeutic target in cancer
-
Wise D.R., Thompson C.B. Glutamine addiction: a new therapeutic target in cancer. Trends Biochem. Sci. 2010, 35(August (8)):427-433.
-
(2010)
Trends Biochem. Sci.
, vol.35
, Issue.AUGUST 8
, pp. 427-433
-
-
Wise, D.R.1
Thompson, C.B.2
-
90
-
-
84884188178
-
Nucleotide degradation and ribose salvage in yeast
-
Xu Y.F., Létisse F., Absalan F., Lu W., Kuznetsova E., Brown G., et al. Nucleotide degradation and ribose salvage in yeast. Mol. Syst. Biol. 2013, 9(May (14)):665.
-
(2013)
Mol. Syst. Biol.
, vol.9
, Issue.MAY 14
, pp. 665
-
-
Xu, Y.F.1
Létisse, F.2
Absalan, F.3
Lu, W.4
Kuznetsova, E.5
Brown, G.6
-
91
-
-
84911103917
-
+ T cell survival and memory formation
-
+ T cell survival and memory formation. Nat. Immunol. 2014, 15(December (12)):1152-1161.
-
(2014)
Nat. Immunol.
, vol.15
, Issue.DECEMBER 12
, pp. 1152-1161
-
-
Xu, X.1
Araki, K.2
Li, S.3
Han, J.H.4
Ye, L.5
Tan, W.G.6
-
92
-
-
78650359602
-
IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid
-
Yabu M., Shime H., Hara H., Saito T., Matsumoto M., Seya T., et al. IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid. Int. Immunol. 2011, 23(1):29-41.
-
(2011)
Int. Immunol.
, vol.23
, Issue.1
, pp. 29-41
-
-
Yabu, M.1
Shime, H.2
Hara, H.3
Saito, T.4
Matsumoto, M.5
Seya, T.6
-
93
-
-
84890137621
-
T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming
-
Yang K., Shrestha S., Zeng H., et al. T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming. Immunity 2013, 39(6):1043-1056.
-
(2013)
Immunity
, vol.39
, Issue.6
, pp. 1043-1056
-
-
Yang, K.1
Shrestha, S.2
Zeng, H.3
-
95
-
-
84922270824
-
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion
-
Zhang J., Fan J., Venneti S., Cross J.R., Takagi T., Bhinder B., et al. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. Mol. Cell. 2014, 56(October (2)):205-218.
-
(2014)
Mol. Cell.
, vol.56
, Issue.OCTOBER 2
, pp. 205-218
-
-
Zhang, J.1
Fan, J.2
Venneti, S.3
Cross, J.R.4
Takagi, T.5
Bhinder, B.6
|