Elucidating central metabolic redox obstacles hindering ethanol production in Clostridium thermocellum

Metabolic Engineering

Volumn 32, Issue , 2015, Pages 207-219

  Thompson, R Adam ^a   Layton, Donovan S ^a,b   Guss, Adam M ^a   Olson, Daniel G ^a,c   Lynd, Lee R ^a,c   Trinh, Cong T ^a,b  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

^b University of Tennessee   (United States)

^c DARTMOUTH COLLEGE   (United States)

Author keywords

Clostridium thermocellum; Elementary mode analysis; Energy metabolism; Ethanol; Minimal metabolic functionality; Redox metabolism

Indexed keywords

BACTERIA; CARBON; CLOSTRIDIUM; ETHANOL; METABOLISM; PHYSIOLOGY;

CLOSTRIDIUM THERMOCELLUM; ELEMENTARY MODE ANALYSIS; ENERGY METABOLISM; MINIMAL METABOLIC FUNCTIONALITY; REDOX METABOLISM;

METABOLIC ENGINEERING;

ACETYL COENZYME A; ALCOHOL; FERREDOXIN; GLYCOLYTIC ENZYME; PHOSPHOENOLPYRUVATE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; HYDROGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ALCOHOL PRODUCTION; ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL STRAIN; BACTERIUM MUTANT; BATCH FERMENTATION; BIOREACTOR; CLOSTRIDIUM THERMOCELLUM; COMPUTER MODEL; COMPUTER PREDICTION; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME SPECIFICITY; GENETIC MANIPULATION; GENOTYPE; METABOLIC ENGINEERING; NONHUMAN; OXIDATION REDUCTION STATE; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ALGORITHM; BIOMASS; ELECTRON; ENZYMOLOGY; FERMENTATION; GENETICS; GLYCOLYSIS; METABOLISM; MUTATION; OXIDATION REDUCTION REACTION;

ALGORITHMS; BIOMASS; CLOSTRIDIUM THERMOCELLUM; ELECTRONS; ETHANOL; FERMENTATION; FERREDOXINS; GLYCOLYSIS; HYDROGEN; METABOLIC ENGINEERING; MUTATION; NADP; OXIDATION-REDUCTION;

EID: 84948147201     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.10.004     Document Type: Article

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