Saturated fatty acids regulate retinoic acid signalling and suppress tumorigenesis by targeting fatty acid-binding protein 5

Nature Communications

Volumn 6, Issue , 2015, Pages

  Levi, Liraz ^a   Wang, Zeneng ^a   Doud, Mary Kathryn ^a,b   Hazen, Stanley L ^a   Noy, Noa ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN 5; LONG CHAIN FATTY ACID; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; RETINOIC ACID; RETINOIC ACID RECEPTOR; SATURATED FATTY ACID; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID; FABP5 PROTEIN, HUMAN; FATTY ACID;

CANCER; CELLS AND CELL COMPONENTS; DRUG; FATTY ACID; GENE EXPRESSION; LIGAND; METABOLITE; PROTEIN; TUMOR;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CARCINOMA CELL; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MCF 7 CELL LINE; MOUSE; MTT ASSAY; NONHUMAN; PROSTATE CANCER CELL LINE; PROTEIN LIPID INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; DOWN REGULATION; GENETICS; METABOLISM; TUMOR CELL LINE;

CARCINOGENESIS; CELL LINE, TUMOR; DOWN-REGULATION; FATTY ACID-BINDING PROTEINS; FATTY ACIDS; HUMANS; PPAR DELTA; PPAR-BETA; RECEPTORS, RETINOIC ACID; SIGNAL TRANSDUCTION; TRETINOIN;

EID: 84947968203     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9794     Document Type: Article

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