Fatty acid-binding protein 5 (fabp5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferatoractivated receptor α/β (pparα/β) in the brain

Journal of Biological Chemistry

Volumn 289, Issue 18, 2014, Pages 12748-12758

  Yu, Shuiliang ^a   Levi, Liraz ^a   Casadesus, Gemma ^a   Kunos, George ^a   Noy, Noa ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; MAMMALS;

ANANDAMIDE; ANANDAMIDE LEVELS; COGNITIVE FUNCTIONS; ENDOCANNABINOID; FATTY ACID-BINDING PROTEINS; LEARNING AND MEMORY; NUCLEAR RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR;

CHEMICAL ACTIVATION;

ANANDAMIDE; ARACHIDONIC ACID; BRAIN PROTEIN; CANNABINOID 1 RECEPTOR; CELL NUCLEUS RECEPTOR; ENDOCANNABINOID; FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN 5; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CELL NUCLEUS; COGNITION; CONTROLLED STUDY; GENE CONTROL; GENETIC ASSOCIATION; HIPPOCAMPUS; HYDROLYSIS; IN VIVO STUDY; LEARNING DISORDER; MEMORY DISORDER; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; UPREGULATION;

ARACHIDONIC ACID; ENDOCANNABINOIDS; LIPID-BINDING PROTEIN; LIPIDS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR);

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ARACHIDONIC ACIDS; BLOTTING, WESTERN; BRAIN; CELL LINE, TUMOR; CELL NUCLEUS; COGNITION; ENDOCANNABINOIDS; FATTY ACID-BINDING PROTEINS; GENE REGULATORY NETWORKS; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYUNSATURATED ALKAMIDES; PPAR DELTA; PPAR-BETA; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIAZOLES; TRANSCRIPTOME;

EID: 84899735022     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.559062     Document Type: Article

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