Borneol depresses P-glycoprotein function by a NF-κB signaling mediated mechanism in a blood brain barrier in vitro model

International Journal of Molecular Sciences

Volumn 16, Issue 11, 2015, Pages 27576-27588

  Fan, Xiang ^a   Chai, Lijuan ^a   Zhang, Han ^a   Wang, Yuefei ^a   Zhang, Boli ^a   Gao, Xiumei ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Blood brain barrier; Borneol; Brain microvascular endothelial cells; NF B; P glycoprotein

Indexed keywords

BORNEOL; CYCLOSPORIN A; DIGOXIN; GAMMA GLUTAMYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1A; RHODAMINE 123; UNCLASSIFIED DRUG; VERAPAMIL; BORNANE DERIVATIVE; ISOBORNEOL;

ANIMAL CELL; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; INTRACELLULAR SPACE; NONHUMAN; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CHEMISTRY; DRUG EFFECTS; ELECTROPHYSIOLOGY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; ASTROCYTES; BLOOD-BRAIN BARRIER; BORNANES; ELECTROPHYSIOLOGICAL PHENOMENA; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; IN VITRO TECHNIQUES; NF-KAPPA B; P-GLYCOPROTEIN; RATS; SIGNAL TRANSDUCTION;

EID: 84947573593     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms161126051     Document Type: Article

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