Improved blood-brain barrier distribution: Effect of borneol on the brain pharmacokinetics of kaempferol in rats by in vivo microdialysis sampling

Journal of Ethnopharmacology

Volumn 162, Issue , 2015, Pages 270-277

  Zhang, Qi ^a   Wu, Dong ^a   Wu, Juan ^a   Ou, Yong ^a   Mu, Chunlei ^a   Han, Bo ^a   Zhang, Qunlin ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Bloodbrain barrier; Borneol; Chemiluminescence; Kaempferol; Microdialysis; Pharmacokinetics

Indexed keywords

BORNEOL; KAEMPFEROL; BORNANE DERIVATIVE; ISOBORNEOL; KAEMPFEROL DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; CHEMOLUMINESCENCE; CHINESE MEDICINE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG GLUCURONIDATION; DRUG HALF LIFE; DRUG TRANSFORMATION; EC50; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; LIMIT OF DETECTION; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MEASUREMENT ACCURACY; MEMBRANE PERMEABILITY; MICRODIALYSIS; MOLECULAR WEIGHT; NONHUMAN; RAT; ANIMAL; DRUG INTERACTION; HALF LIFE TIME; METABOLISM; PROCEDURES; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; AREA UNDER CURVE; BLOOD-BRAIN BARRIER; BORNANES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG INTERACTIONS; HALF-LIFE; KAEMPFEROLS; MALE; MICRODIALYSIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84921646548     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.01.003     Document Type: Article

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