Signalling pathways influencing basal and H2O 2-induced P-glycoprotein expression in endothelial cells derived from the blood-brain barrier

Journal of Neurochemistry

Volumn 87, Issue 4, 2003, Pages 1043-1051

  Nwaozuzu, Osi M ^a   Sellers, Lynda A ^b   Barrand, Margery A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

Blood brain barrier; Hydrogen peroxide; MAP kinases; NF B; P glycoprotein; Rat brain endothelium

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 MORPHOLINO 8 PHENYLCHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; GLYCOPROTEIN P; HYDROGEN PEROXIDE; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN C JUN; PROTEIN INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; SN 50; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN NERVE CELL; CELL CULTURE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; EXPOSURE; EXTRACELLULAR SPACE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENE EXPRESSION; HYDROGEN PEROXIDE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; OXIDANTS; P-GLYCOPROTEIN; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-JUN; RATS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0344393071     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02061.x     Document Type: Article

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