Engineered Mammalian RNAi Can Elicit Antiviral Protection that Negates the Requirement for the Interferon Response

Cell Reports

Volumn 13, Issue 7, 2015, Pages 1456-1466

  Benitez, Asiel Arturo ^a   Spanko, Laura Adrienne ^a   Bouhaddou, Mehdi ^a   Sachs, David ^a   tenOever, Benjamin Robert ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; MICRORNA; NONSTRUCTURAL PROTEIN 1; SMALL INTERFERING RNA; SPACER DNA; VIRUS DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; GENETIC ENGINEERING; IN VIVO STUDY; INFECTION PREVENTION; INFLUENZA A VIRUS; INNATE IMMUNITY; INTERFERON RESPONSE; MAMMAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; RNA SYNTHESIS; SPECIES DIFFERENCE; VIRUS ATTENUATION; VIRUS INHIBITION; VIRUS LOAD; VIRUS STRAIN; ANIMAL; C57BL MOUSE; DISEASE RESISTANCE; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; INVERTED REPEAT; KNOCKOUT MOUSE; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ANIMALS; BASE SEQUENCE; DISEASE RESISTANCE; DNA, INTERGENIC; DNA, VIRAL; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INFLUENZA A VIRUS; INTERFERONS; INVERTED REPEAT SEQUENCES; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; RNA INTERFERENCE; SPECIES SPECIFICITY;

EID: 84947300871     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.10.020     Document Type: Article

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