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Volumn 289, Issue 36, 2014, Pages 25186-25198

Antiviral responses in mouse embryonic stem cells: Differential development of cellular mechanisms in type I interferon production and response

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CELL CULTURE; GENES; GLYCOPROTEINS; INTERFERONS; MAMMALS; TISSUE; VIRUSES;

EID: 84906962772     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.537746     Document Type: Article
Times cited : (29)

References (65)
  • 1
    • 33947308285 scopus 로고    scopus 로고
    • How is pluripotency determined and maintained?
    • Niwa, H. (2007) How is pluripotency determined and maintained? Development 134, 635-646
    • (2007) Development , vol.134 , pp. 635-646
    • Niwa, H.1
  • 2
    • 15544383394 scopus 로고    scopus 로고
    • Embryonic stem cells: Prospects for developmental biology and cell therapy
    • Wobus, A. M., and Boheler, K. R. (2005) Embryonic stem cells: prospects for developmental biology and cell therapy. Physiol. Rev. 85, 635-678
    • (2005) Physiol. Rev. , vol.85 , pp. 635-678
    • Wobus, A.M.1    Boheler, K.R.2
  • 4
    • 33745744362 scopus 로고    scopus 로고
    • TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications
    • Zampetaki, A., Xiao, Q., Zeng, L., Hu, Y., and Xu, Q. (2006) TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications. Biochem. Biophys. Res. Commun. 347, 89-99
    • (2006) Biochem. Biophys. Res. Commun. , vol.347 , pp. 89-99
    • Zampetaki, A.1    Xiao, Q.2    Zeng, L.3    Hu, Y.4    Xu, Q.5
  • 6
    • 54849431788 scopus 로고    scopus 로고
    • NF-κB, but not p38 MAP kinase, is required for TNF-α-induced expression of cell adhesion molecules in endothelial cells
    • Rajan, S., Ye, J., Bai, S., Huang, F., and Guo, Y. L. (2008) NF-κB, but not p38 MAP kinase, is required for TNF-α-induced expression of cell adhesion molecules in endothelial cells. J. Cell. Biochem. 105, 477-486
    • (2008) J. Cell. Biochem. , vol.105 , pp. 477-486
    • Rajan, S.1    Ye, J.2    Bai, S.3    Huang, F.4    Guo, Y.L.5
  • 7
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai, T., and Akira, S. (2011) Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34, 637-650
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 8
    • 80052143412 scopus 로고    scopus 로고
    • RIG-I-like receptors: Cytoplasmic sensors for non-self RNA
    • Kato, H., Takahasi, K., and Fujita, T. (2011) RIG-I-like receptors: cytoplasmic sensors for non-self RNA. Immunol. Rev. 243, 91-98
    • (2011) Immunol. Rev. , vol.243 , pp. 91-98
    • Kato, H.1    Takahasi, K.2    Fujita, T.3
  • 9
    • 0034769960 scopus 로고    scopus 로고
    • Viruses and interferons
    • Sen, G. C. (2001) Viruses and interferons. Annu. Rev. Microbiol. 55, 255-281
    • (2001) Annu. Rev. Microbiol. , vol.55 , pp. 255-281
    • Sen, G.C.1
  • 10
    • 35048854047 scopus 로고    scopus 로고
    • Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-α is rescued by HDAC inhibitor trichostatin A
    • Zampetaki, A., Zeng, L., Xiao, Q., Margariti, A., Hu, Y., and Xu, Q. (2007) Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-α is rescued by HDAC inhibitor trichostatin A. Am. J. Physiol. Cell Physiol. 293, C1226-C1238
    • (2007) Am. J. Physiol. Cell Physiol. , vol.293 , pp. C1226-C1238
    • Zampetaki, A.1    Zeng, L.2    Xiao, Q.3    Margariti, A.4    Hu, Y.5    Xu, Q.6
  • 11
    • 60549098416 scopus 로고    scopus 로고
    • Interaction of enteric bacterial pathogens with murine embryonic stem cells
    • Yu, J., Rossi, R., Hale, C., Goulding, D., and Dougan, G. (2009) Interaction of enteric bacterial pathogens with murine embryonic stem cells. Infect. Immun. 77, 585-597
    • (2009) Infect. Immun. , vol.77 , pp. 585-597
    • Yu, J.1    Rossi, R.2    Hale, C.3    Goulding, D.4    Dougan, G.5
  • 13
    • 84878386885 scopus 로고    scopus 로고
    • Mouse embryonic stem cells are deficient in type I interferon expression in response to viral infections and double-stranded RNA
    • Wang, R., Wang, J., Paul, A. M., Acharya, D., Bai, F., Huang, F., and Guo, Y. L. (2013) Mouse embryonic stem cells are deficient in type I interferon expression in response to viral infections and double-stranded RNA. J. Biol. Chem. 288, 15926-15936
    • (2013) J. Biol. Chem. , vol.288 , pp. 15926-15936
    • Wang, R.1    Wang, J.2    Paul, A.M.3    Acharya, D.4    Bai, F.5    Huang, F.6    Guo, Y.L.7
  • 14
    • 84895754378 scopus 로고    scopus 로고
    • Mouse embryonic stem cells have underdeveloped antiviral mechanisms that can be exploited for the development of mRNA-mediated gene expression strategy
    • Wang, R., Teng, C., Spangler, J., Wang, J., Huang, F., and Guo, Y.-L. (2014) Mouse embryonic stem cells have underdeveloped antiviral mechanisms that can be exploited for the development of mRNA-mediated gene expression strategy. Stem Cells Dev. 23, 594-604
    • (2014) Stem Cells Dev. , vol.23 , pp. 594-604
    • Wang, R.1    Teng, C.2    Spangler, J.3    Wang, J.4    Huang, F.5    Guo, Y.-L.6
  • 15
    • 77956417791 scopus 로고    scopus 로고
    • Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells
    • Chen, L. L., Yang, L., and Carmichael, G. G. (2010) Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells. Cell Cycle 9, 3552-3564
    • (2010) Cell Cycle , vol.9 , pp. 3552-3564
    • Chen, L.L.1    Yang, L.2    Carmichael, G.G.3
  • 17
    • 0034767753 scopus 로고    scopus 로고
    • Antiviral actions of interferons
    • Samuel, C. E. (2001) Antiviral actions of interferons. Clin. Microbiol. Rev. 14, 778-809
    • (2001) Clin. Microbiol. Rev. , vol.14 , pp. 778-809
    • Samuel, C.E.1
  • 18
    • 36749086446 scopus 로고    scopus 로고
    • 5′-Triphosphate-dependent activation of PKR by RNAs with short stem-loops
    • Nallagatla, S. R., Hwang, J., Toroney, R., Zheng, X., Cameron, C. E., and Bevilacqua, P. C. (2007) 5′-Triphosphate-dependent activation of PKR by RNAs with short stem-loops. Science 318, 1455-1458
    • (2007) Science , vol.318 , pp. 1455-1458
    • Nallagatla, S.R.1    Hwang, J.2    Toroney, R.3    Zheng, X.4    Cameron, C.E.5    Bevilacqua, P.C.6
  • 19
    • 33748455338 scopus 로고    scopus 로고
    • Type I interferons in host defense
    • Stetson, D. B., and Medzhitov, R. (2006) Type I interferons in host defense. Immunity 25, 373-381
    • (2006) Immunity , vol.25 , pp. 373-381
    • Stetson, D.B.1    Medzhitov, R.2
  • 20
    • 84878417838 scopus 로고    scopus 로고
    • Innate immunity in pluripotent human cells: Attenuated response to interferon-β
    • Hong, X. X., and Carmichael, G. G. (2013) Innate immunity in pluripotent human cells: attenuated response to interferon-β. J. Biol. Chem. 288, 16196-16205
    • (2013) J. Biol. Chem. , vol.288 , pp. 16196-16205
    • Hong, X.X.1    Carmichael, G.G.2
  • 21
    • 15544387798 scopus 로고    scopus 로고
    • Use of RNA interference to prevent lethal murine West Nile Virus infection
    • Bai, F., Wang, T., Pal, U., Bao, F., Gould, L. H., and Fikrig, E. (2005) Use of RNA interference to prevent lethal murine West Nile Virus infection. J. Infect. Dis. 191, 1148-1154
    • (2005) J. Infect. Dis. , vol.191 , pp. 1148-1154
    • Bai, F.1    Wang, T.2    Pal, U.3    Bao, F.4    Gould, L.H.5    Fikrig, E.6
  • 22
    • 84860428468 scopus 로고    scopus 로고
    • Efficient differentiation of embryonic stem cells into mesodermal precursors by BMP, retinoic acid, and Notch signalling
    • Torres, J., Prieto, J., Durupt, F. C., Broad, S., and Watt, F. M. (2012) Efficient differentiation of embryonic stem cells into mesodermal precursors by BMP, retinoic acid, and Notch signalling. PLoS ONE 7, e36405
    • (2012) PLoS ONE , vol.7 , pp. e36405
    • Torres, J.1    Prieto, J.2    Durupt, F.C.3    Broad, S.4    Watt, F.M.5
  • 25
    • 0028100466 scopus 로고
    • Cross-species antiviral and antiproliferative activity of human interferon-ω
    • Kubes, M., Fuchsberger, N., and Kontsek, P. (1994) Cross-species antiviral and antiproliferative activity of human interferon-ω. J. Interferon Res. 14, 57-59
    • (1994) J. Interferon Res. , vol.14 , pp. 57-59
    • Kubes, M.1    Fuchsberger, N.2    Kontsek, P.3
  • 26
    • 37249033113 scopus 로고    scopus 로고
    • p38α MAP kinase-deficient mouse embryonic stem cells can differentiate to endothelial cells, smooth muscle cells, and neurons
    • Guo, Y. L., Ye, J., and Huang, F. (2007) p38α MAP kinase-deficient mouse embryonic stem cells can differentiate to endothelial cells, smooth muscle cells, and neurons. Dev. Dyn. 236, 3383-3392
    • (2007) Dev. Dyn. , vol.236 , pp. 3383-3392
    • Guo, Y.L.1    Ye, J.2    Huang, F.3
  • 27
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl, M. W. (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, e45
    • (2001) Nucleic Acids Res. , vol.29 , pp. e45
    • Pfaffl, M.W.1
  • 28
    • 77956427364 scopus 로고    scopus 로고
    • Effects of oxidative stress on mouse embryonic stem cell proliferation, apoptosis, senescence, and self-renewal
    • Guo, Y. L., Chakraborty, S., Rajan, S. S., Wang, R., and Huang, F. (2010) Effects of oxidative stress on mouse embryonic stem cell proliferation, apoptosis, senescence, and self-renewal. Stem Cells Dev. 19, 1321-1331
    • (2010) Stem Cells Dev. , vol.19 , pp. 1321-1331
    • Guo, Y.L.1    Chakraborty, S.2    Rajan, S.S.3    Wang, R.4    Huang, F.5
  • 29
    • 84864316900 scopus 로고    scopus 로고
    • Transient inhibition of cell proliferation does not compromise self-renewal of mouse embryonic stem cells
    • Wang, R., and Guo, Y. L. (2012) Transient inhibition of cell proliferation does not compromise self-renewal of mouse embryonic stem cells. Exp. Cell Res. 318, 2094-2104
    • (2012) Exp. Cell Res. , vol.318 , pp. 2094-2104
    • Wang, R.1    Guo, Y.L.2
  • 30
    • 0032953984 scopus 로고    scopus 로고
    • Tumor necrosis factor-α and ceramide induce cell death through different mechanisms in rat mesangial cells
    • Guo, Y. L., Kang, B., Yang, L. J., and Williamson, J. R. (1999) Tumor necrosis factor-α and ceramide induce cell death through different mechanisms in rat mesangial cells. Am. J. Physiol. 276, F390-F397
    • (1999) Am. J. Physiol. , vol.276 , pp. F390-F397
    • Guo, Y.L.1    Kang, B.2    Yang, L.J.3    Williamson, J.R.4
  • 31
    • 0242416538 scopus 로고    scopus 로고
    • Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs
    • Streitenfeld, H., Boyd, A., Fazakerley, J. K., Bridgen, A., Elliott, R. M., and Weber, F. (2003) Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs. J. Virol. 77, 5507-5511
    • (2003) J. Virol. , vol.77 , pp. 5507-5511
    • Streitenfeld, H.1    Boyd, A.2    Fazakerley, J.K.3    Bridgen, A.4    Elliott, R.M.5    Weber, F.6
  • 32
    • 77957554950 scopus 로고    scopus 로고
    • Bunyaviruses and the type I interferon system
    • Elliott, R. M., and Weber, F. (2009) Bunyaviruses and the type I interferon system. Viruses 1, 1003-1021
    • (2009) Viruses , vol.1 , pp. 1003-1021
    • Elliott, R.M.1    Weber, F.2
  • 33
    • 77954537038 scopus 로고    scopus 로고
    • La Crosse virus (LACV) Gc fusion peptide mutants have impaired growth and fusion phenotypes, but remain neurotoxic
    • Soldan, S. S., Hollidge, B. S., Wagner, V., Weber, F., and González-Scarano, F. (2010) La Crosse virus (LACV) Gc fusion peptide mutants have impaired growth and fusion phenotypes, but remain neurotoxic. Virology 404, 139-147
    • (2010) Virology , vol.404 , pp. 139-147
    • Soldan, S.S.1    Hollidge, B.S.2    Wagner, V.3    Weber, F.4    González-Scarano, F.5
  • 35
    • 84866493776 scopus 로고    scopus 로고
    • Deciphering the differential response of two human fibroblast cell lines following Chikungunya virus infection
    • Thon-Hon, V. G., Denizot, M., Li-Pat-Yuen, G., Giry, C., Jaffar-Bandjee, M. C., and Gasque, P. (2012) Deciphering the differential response of two human fibroblast cell lines following Chikungunya virus infection. Virol. J. 9, 213
    • (2012) Virol. J. , vol.9 , pp. 213
    • Thon-Hon, V.G.1    Denizot, M.2    Li-Pat-Yuen, G.3    Giry, C.4    Jaffar-Bandjee, M.C.5    Gasque, P.6
  • 36
    • 34347225099 scopus 로고    scopus 로고
    • The dsRNA protein kinase PKR: Virus and cell control
    • García, M. A., Meurs, E. F., and Esteban, M. (2007) The dsRNA protein kinase PKR: virus and cell control. Biochimie 89, 799-811
    • (2007) Biochimie , vol.89 , pp. 799-811
    • García, M.A.1    Meurs, E.F.2    Esteban, M.3
  • 37
    • 77957785465 scopus 로고    scopus 로고
    • Emerging role of ISG15 in antiviral immunity
    • Skaug, B., and Chen, Z. J. (2010) Emerging role of ISG15 in antiviral immunity. Cell 143, 187-190
    • (2010) Cell , vol.143 , pp. 187-190
    • Skaug, B.1    Chen, Z.J.2
  • 38
    • 0015073685 scopus 로고
    • Priming: A nonantiviral function of interferon
    • Stewart, W. E., 2nd., Gosser, L. B., and Lockart, R. Z., Jr. (1971) Priming: a nonantiviral function of interferon. J. Virol. 7, 792-801
    • (1971) J. Virol. , vol.7 , pp. 792-801
    • Stewart, W.E.1    Gosser, L.B.2    Lockart, R.Z.3
  • 40
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I- and type-II-interferon-mediated signalling
    • Platanias, L. C. (2005) Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat. Rev. Immunol. 5, 375-386
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 375-386
    • Platanias, L.C.1
  • 42
    • 18844396119 scopus 로고    scopus 로고
    • Embryonic stem cell differentiation: Emergence of a new era in biology and medicine
    • Keller, G. (2005) Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev. 19, 1129-1155
    • (2005) Genes Dev. , vol.19 , pp. 1129-1155
    • Keller, G.1
  • 43
    • 0015752438 scopus 로고
    • Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division
    • Reznikoff, C. A., Brankow, D. W., and Heidelberger, C. (1973) Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division. Cancer Res. 33, 3231-3238
    • (1973) Cancer Res. , vol.33 , pp. 3231-3238
    • Reznikoff, C.A.1    Brankow, D.W.2    Heidelberger, C.3
  • 44
    • 0035159094 scopus 로고    scopus 로고
    • α-Smooth muscle actin expression upregulates fibroblast contractile activity
    • Hinz, B., Celetta, G., Tomasek, J. J., Gabbiani, G., and Chaponnier, C. (2001) α-Smooth muscle actin expression upregulates fibroblast contractile activity. Mol. Biol. Cell 12, 2730-2741
    • (2001) Mol. Biol. Cell , vol.12 , pp. 2730-2741
    • Hinz, B.1    Celetta, G.2    Tomasek, J.J.3    Gabbiani, G.4    Chaponnier, C.5
  • 45
    • 4644269059 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization
    • Paik, J. H., Skoura, A., Chae, S. S., Cowan, A. E., Han, D. K., Proia, R. L., and Hla, T. (2004) Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization. Genes Dev. 18, 2392-2403
    • (2004) Genes Dev. , vol.18 , pp. 2392-2403
    • Paik, J.H.1    Skoura, A.2    Chae, S.S.3    Cowan, A.E.4    Han, D.K.5    Proia, R.L.6    Hla, T.7
  • 46
    • 0035670380 scopus 로고    scopus 로고
    • TGFβ is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells
    • Darland, D. C., and D'Amore, P. A. (2001) TGFβ is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells. Angiogenesis 4, 11-20
    • (2001) Angiogenesis , vol.4 , pp. 11-20
    • Darland, D.C.1    D'Amore, P.A.2
  • 47
    • 80055089437 scopus 로고    scopus 로고
    • Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis
    • Cheng, G., Liao, S., Kit Wong, H., Lacorre, D. A., di Tomaso, E., Au, P., Fukumura, D., Jain, R. K., and Munn, L. L. (2011) Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis. Blood 118, 4740-4749
    • (2011) Blood , vol.118 , pp. 4740-4749
    • Cheng, G.1    Liao, S.2    Kit Wong, H.3    Lacorre, D.A.4    Di Tomaso, E.5    Au, P.6    Fukumura, D.7    Jain, R.K.8    Munn, L.L.9
  • 48
    • 0037331234 scopus 로고    scopus 로고
    • Global expression profiling of fibroblast responses to transforming growth factor-β1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching
    • Chambers, R. C., Leoni, P., Kaminski, N., Laurent, G. J., and Heller, R. A. (2003) Global expression profiling of fibroblast responses to transforming growth factor-β1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching. Am. J. Pathol. 162, 533-546
    • (2003) Am. J. Pathol. , vol.162 , pp. 533-546
    • Chambers, R.C.1    Leoni, P.2    Kaminski, N.3    Laurent, G.J.4    Heller, R.A.5
  • 49
    • 0027517288 scopus 로고
    • The responsiveness of embryonic stem cells to α and β interferons provides the basis of an inducible expression system for analysis of developmental control genes
    • Whyatt, L. M., Düwel, A., Smith, A. G., and Rathjen, P. D. (1993) The responsiveness of embryonic stem cells to α and β interferons provides the basis of an inducible expression system for analysis of developmental control genes. Mol. Cell. Biol. 13, 7971-7976
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7971-7976
    • Whyatt, L.M.1    Düwel, A.2    Smith, A.G.3    Rathjen, P.D.4
  • 50
    • 0027140510 scopus 로고
    • Induction of type I interferon genes and interferon-inducible genes in embryonal stem cells devoid of interferon regulatory factor 1
    • Ruffner, H., Reis, L. F., Näf, D., and Weissmann, C. (1993) Induction of type I interferon genes and interferon-inducible genes in embryonal stem cells devoid of interferon regulatory factor 1. Proc. Natl. Acad. Sci. U.S.A. 90, 11503-11507
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 11503-11507
    • Ruffner, H.1    Reis, L.F.2    Näf, D.3    Weissmann, C.4
  • 52
    • 0037259517 scopus 로고    scopus 로고
    • Infection efficiency of human and mouse embryonic stem cells using adenoviral and adeno-associated viral vectors
    • Smith-Arica, J. R., Thomson, A. J., Ansell, R., Chiorini, J., Davidson, B., and McWhir, J. (2003) Infection efficiency of human and mouse embryonic stem cells using adenoviral and adeno-associated viral vectors. Cloning Stem Cells 5, 51-62
    • (2003) Cloning Stem Cells , vol.5 , pp. 51-62
    • Smith-Arica, J.R.1    Thomson, A.J.2    Ansell, R.3    Chiorini, J.4    Davidson, B.5    McWhir, J.6
  • 53
    • 0346121599 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling and immunity
    • Kubo, M., Hanada, T., and Yoshimura, A. (2003) Suppressors of cytokine signaling and immunity. Nat. Immunol. 4, 1169-1176
    • (2003) Nat. Immunol. , vol.4 , pp. 1169-1176
    • Kubo, M.1    Hanada, T.2    Yoshimura, A.3
  • 54
    • 0033517123 scopus 로고    scopus 로고
    • STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
    • Matsuda, T., Nakamura, T., Nakao, K., Arai, T., Katsuki, M., Heike, T., and Yokota, T. (1999) STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J. 18, 4261-4269
    • (1999) EMBO J. , vol.18 , pp. 4261-4269
    • Matsuda, T.1    Nakamura, T.2    Nakao, K.3    Arai, T.4    Katsuki, M.5    Heike, T.6    Yokota, T.7
  • 57
    • 0036709213 scopus 로고    scopus 로고
    • Signalling, cell cycle and pluripotency in embryonic stem cells
    • Burdon, T., Smith, A., and Savatier, P. (2002) Signalling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol. 12, 432-438
    • (2002) Trends Cell Biol. , vol.12 , pp. 432-438
    • Burdon, T.1    Smith, A.2    Savatier, P.3
  • 58
    • 58049202385 scopus 로고    scopus 로고
    • Exposing hidden dimensions of embryonic stem cell cycle control
    • Dalton, S. (2009) Exposing hidden dimensions of embryonic stem cell cycle control. Cell Stem Cell 4, 9-10
    • (2009) Cell Stem Cell , vol.4 , pp. 9-10
    • Dalton, S.1
  • 59
    • 67849092746 scopus 로고    scopus 로고
    • The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming
    • Singh, A. M., and Dalton, S. (2009) The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming. Cell Stem Cell 5, 141-149
    • (2009) Cell Stem Cell , vol.5 , pp. 141-149
    • Singh, A.M.1    Dalton, S.2
  • 60
    • 34247588114 scopus 로고    scopus 로고
    • Innate immunity of the newborn: Basic mechanisms and clinical correlates
    • Levy, O. (2007) Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat. Rev. Immunol. 7, 379-390
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 379-390
    • Levy, O.1
  • 62
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., and Mello, C. C. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 63
    • 84895749135 scopus 로고    scopus 로고
    • Distinct antiviral responses in pluripotent versus differentiated cells
    • Pare, J. M., and Sullivan, C. S. (2014) Distinct antiviral responses in pluripotent versus differentiated cells. PLoS Pathog. 10, e1003865
    • (2014) PLoS Pathog. , vol.10 , pp. e1003865
    • Pare, J.M.1    Sullivan, C.S.2
  • 64
    • 84886066428 scopus 로고    scopus 로고
    • Is RNA interference a physiologically relevant innate antiviral immune response in mammals?
    • Cullen, B. R., Cherry, S., and tenOever, B. R. (2013) Is RNA interference a physiologically relevant innate antiviral immune response in mammals? Cell Host Microbe 14, 374-378
    • (2013) Cell Host Microbe , vol.14 , pp. 374-378
    • Cullen, B.R.1    Cherry, S.2    TenOever, B.R.3
  • 65
    • 84862524446 scopus 로고    scopus 로고
    • RNAi in the regulation of mammalian viral infections
    • Jeang, K. T. (2012) RNAi in the regulation of mammalian viral infections. BMC Biol. 10, 58
    • (2012) BMC Biol. , vol.10 , pp. 58
    • Jeang, K.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.