Hepatic expression of HCV RNA-dependent RNA polymerase triggers innate immune signaling and cytokine production

Molecular Cell

Volumn 48, Issue 2, 2012, Pages 313-321

  Yu, Guann Yi ^a,b,c   He, Guobin ^a   Li, Chia Yang ^b   Tang, Martin ^a   Grivennikov, Sergei ^a   Tsai, Wan Ting ^b   Wu, Ming Sian ^b   Hsu, Chih Wen ^b   Tsai, Yu ^b   Wang, Lily Hui Ching ^d   Karin, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 6; NONSTRUCTURAL PROTEIN 5B; RNA DIRECTED RNA POLYMERASE;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; INNATE IMMUNITY; LIVER; LIVER CELL; LIVER INJURY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; HEPACIVIRUS; HEPATITIS C, CHRONIC; HEPATOCYTES; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; INTERLEUKIN-6; LIVER; MICE; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 84868090808     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2012.07.032     Document Type: Article

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