Investigating the dynamic nature of the ABC transporters: ABCB1 and MsbA as examples for the potential synergies of MD theory and EPR applications

Biochemical Society Transactions

Volumn 43, Issue , 2015, Pages 1023-1032

  Stockner, Thomas ^a   Mullen, Anna ^b   MacMillan, Fraser ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

ABCB1; DEER; EPR; MD simulations; Modelling; MsbA; PELDOR; Protein dynamics

Indexed keywords

MSBA PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; ABC TRANSPORTER; ABCB1 PROTEIN, HUMAN; ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEIN; MSBA PROTEIN, BACTERIA; MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ELECTRON SPIN RESONANCE; HUMAN; MAGNITUDE ESTIMATION METHOD; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; SPIN LABELING; CHEMISTRY; METABOLISM; PROCEDURES; PROTEIN TERTIARY STRUCTURE; REPRODUCIBILITY; TRANSPORT AT THE CELLULAR LEVEL; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; CRYSTALLOGRAPHY, X-RAY; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; MOLECULAR DYNAMICS SIMULATION; P-GLYCOPROTEINS; PROTEIN STRUCTURE, TERTIARY; REPRODUCIBILITY OF RESULTS;

EID: 84947223826     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20150138     Document Type: Article

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