Characterization of the E506Q and H537A dysfunctional mutants in the E. coli abc transporter MsbA

Biochemistry

Volumn 50, Issue 18, 2011, Pages 3599-3608

  Schultz, Kathryn M ^a   Merten, Jacqueline A ^a   Klug, Candice S ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ATP BINDING; ATP DETECTION; ATPASE DOMAIN; CELL VIABILITY; DRUG RESISTANCE; DYSFUNCTIONAL PROTEINS; E. COLI; EPR SPECTROSCOPY; GLOBAL EFFECTS; GRAM-NEGATIVE BACTERIA; HOMODIMERS; IN-VIVO; LIPID A; MUTANT PROTEINS; NUCLEOTIDE-BINDING DOMAIN;

ASSAYS; BACTERIA; BACTERIOLOGY; BINDING SITES; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; HYDROLYSIS; NUCLEOTIDES; PARAMAGNETIC RESONANCE;

PROTEINS;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; HOMODIMER; MSBA PROTEIN; MUTANT PROTEIN; NUCLEOTIDE BINDING PROTEIN;

ARTICLE; CELL GROWTH; CELL VIABILITY; CHEMICAL ANALYSIS; CONTROLLED STUDY; DOUBLE ELECTRON ELECTRON RESONANCE; ELECTRON SPIN RESONANCE; ESCHERICHIA COLI; GENE MUTATION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PURIFICATION; SPECTROSCOPY;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; CYSTEINE; DIMERIZATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; HYDROLYSIS; KINETICS; LIPID A; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEOTIDES; PROTEIN BINDING;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 79955628177     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101666p     Document Type: Article

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